Research Topics
| Parul J ShuklaSummaryCountry: UK Publications
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Publications
Modification in the technique of pancreaticoduodenectomy: supracolic division of jejunum to facilitate uncinate process dissectionP J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Hepatogastroenterology 54:1728-30. 2007..It helps in aligning the uncinate process with the jejunal mesentery thereby making the dissection of uncinate process from the superior mesenteric vessels safe and complete...
Detection of gall bladder cancer metastases in rare sites by PET scanParul J Shukla
Indian J Gastroenterol 26:303-4. 2007
Questionable benefit of short course radiotherapy for rectal cancerSavio George Barreto
Ann Surg 247:1086; author reply 1086-7. 2008
Vascular anomalies encountered during pancreatoduodenectomy: do they influence outcomes?Parul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Ann Surg Oncol 17:186-93. 2010..Because of the potential risk of hemorrhage or ischemia, the presence of vascular anomalies adds to the surgical challenge in pancreatoduodenectomy (PD)...
Can we do better than 'incidental' gallbladder cancer?Parul J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Hepatogastroenterology 54:2184-5. 2007....
Do transanastomotic pancreatic ductal stents after pancreatic resections improve outcomes?Parul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Pancreas 39:561-6. 2010..One such procedure, until now incompletely explored, is transanastomotic pancreatic (TAP) ductal stenting...
Is there a role for estrogen and progesterone receptors in gall bladder cancer?P J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
HPB (Oxford) 9:285-8. 2007..This study was carried out to determine the hormone receptors (ER/PR) expression level in gall bladder cancer using specific immunohistochemical assays and correlate it with patient and tumour histopathological characteristics...
Postoperative deep vein thrombosis in patients with colorectal cancerParul J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Indian J Gastroenterol 27:71-3. 2008..No episode of DVT occurred in either the drug arm or the observation arm. There was no death following surgery. The incidence of DVT in Indian patients operated for colorectal cancer in the lithotomy position was negligible...
Pancreato-enteric anastomosis: the duct evagination techniqueParul J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai 400 012, India
J Surg Oncol 100:277-8. 2009..The modification acts as an adjunct to an already established technique yielding good results...
Hepatoblastoma: a single institutional experience of 18 casesParul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai 400 012, India
Pediatr Surg Int 24:799-802. 2008....
A new scoring system for gallbladder cancer (aiding treatment algorithm): an analysis of 335 patientsParul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai 400 012, India
Ann Surg Oncol 15:3132-7. 2008..We thus sought to validate a new scoring system, the Tata Memorial Hospital Staging System (TMHSS), for gallbladder cancer...
The evolution of pancreatoduodenectomyParul J Shukla
Department of Gastointestinal and Hepato Pancreato Biliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Hepatogastroenterology 58:1409-12. 2011..This review aims at highlighting the important milestones in the history of pancreatoduodenectomy leading to its progressive development, whilst providing a scientific basis...
Does pancreatic ductal anatomy play a role in determining outcomes of pancreatic anastomoses?P J Shukla
Gastrointestinal and HPB Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Med Hypotheses 76:230-3. 2011..These factors would alert the surgeon about potential ductal variations and could facilitate the surgical approach...
Toward improving uniformity and standardization in the reporting of pancreatic anastomoses: a new classification system by the International Study Group of Pancreatic Surgery (ISGPS)Parul J Shukla
Department of Gastrointestinal and Hepato Pancreato Biliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Surgery 147:144-53. 2010..To date, there is no uniform and standardized manner of defining pancreatic anastomoses after pancreatic resection...
Application of Six Sigma towards improving surgical outcomesP J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Hepatogastroenterology 55:311-4. 2008..The aim of this study is to apply the Six Sigma methodology into a clinical surgical process and to assess the improvement (if any) in the outcomes and patient care...
Feasibility of laparoscopic abdomino-perineal resection for large-sized anorectal cancers: a single-institution experience of 59 casesParul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Indian J Med Sci 63:109-14. 2009..Laparoscopic surgery for anorectal carcinoma is steadily gaining acceptance. While feasibility has already been reported, there are no reports addressing the impact of the actual size of large tumors on laparoscopic resectability...
Impact of intra-operative ultrasonography in liver surgeryParul J Shukla
Department of GI Surgical Oncology, Tata Memorial Hospital, Mumbai
Indian J Gastroenterol 24:62-5. 2005..We assessed the impact of IOUS in liver surgery at our hospital, a tertiary-care cancer center...
Reoperative pancreaticoduodenectomy for periampullary carcinomaParul J Shukla
Department of Gastrointestinal Surgery, Tata Memorial Hospital, Parel, Bombay, India
ANZ J Surg 75:520-3. 2005..The purpose of the present paper was to determine the perioperative morbidity and mortality for patients undergoing reoperative pancreaticoduodenectomy at a major comprehensive cancer centre...
Breast metastases of gastric signet ring cell carcinoma: a differential diagnosis with primary breast signet ring cell carcinomaS S Qureshi
Department of Surgical Gastroenterology, Tata Memorial Hospital, Parel, Mumbai, India
J Postgrad Med 51:125-7. 2005..In this report, we present a case of signet ring cell stomach cancer with metastasis to the breast and discuss the differential diagnostic options...
Managing leaks following anterior resections: a new classification systemParul J Shukla
Tata Memorial Hospital, Mumbai, India
Hepatogastroenterology 58:1095-8. 2011..3%. The aim of our study was to identify those patients who had developed an anastomotic leak, and evaluate the indications for re-exploration as well as study the impact of covering colostomies on the subsequent outcome...
Simultaneous gallbladder and bile duct cancers: revisiting the pathological possibilitiesP J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
HPB (Oxford) 10:48-53. 2008....
Defining the role of surgery for complications after pancreatoduodenectomyParul J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
ANZ J Surg 79:33-7. 2009..The aim of the study was to define the role of surgery for dealing with complications following pancreatoduodenectomy...
Surgery for malignant liver tumorsParul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
J Cancer Res Ther 5:154-60. 2009..RFA is emerging as a useful, often complimentary tool, to surgery when dealing with complex tumors or tumors in patients with a poor liver function. Laparoscopic ultrasonography is useful in staging and performance of RFA...
Pancreatic fistula after pancreaticoduodenectomy: the impact of a standardized technique of pancreaticojejunostomyShailesh V Shrikhande
Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Ernest Borges Marg, Parel, Mumbai 400 012, India
Langenbecks Arch Surg 393:87-91. 2008..The role of standardization on outcomes after pancreaticoduodenectomy has not been sufficiently addressed...
Superior mesenteric artery first combined with uncinate process approach versus uncinate process first approach in pancreatoduodenectomy: a comparative study evaluating perioperative outcomesShailesh V Shrikhande
Department of Gastrointestinal and Hepato Pancreato Biliary Surgery, Tata Memorial Hospital, Mumbai, India
Langenbecks Arch Surg 396:1205-12. 2011..During pancreatoduodenectomy (PD), two techniques have been described to dissect the head of pancreas, viz. the superior mesenteric artery (SMA) approach by dissecting the uncinate process and the uncinate process first approach...
Three cases of unusual solid pseudopapillary tumors. Can radiology and histology aid decision-making?Soheil Shaikh
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital Mumbai, India
JOP 9:150-9. 2008..The tendency of some of these tumors to be locally aggressive and also to metastasize has been well recognized. It is not possible to predict the biologic behavior of these tumors based only on their morphology...
Borderline resectable pancreatic tumors: is there a need for further refinement of this stage?Shailesh V Shrikhande
Department of Hepato Pancreato Biliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Hepatobiliary Pancreat Dis Int 10:319-24. 2011..The aim of the present study was to identify specific findings on preoperative imaging that could help predict in which patients with BRT a complete resection, with or without vascular resection (VR), could be achieved...
Gastrointestinal stromal tumors: case series of 29 patients defining the role of imatinib prior to surgeryShailesh V Shrikhande
Department of Gastrointestinal and HPB Surgical Oncology, Tata Memorial Hospital, Ernest Borges Marg, Parel, Mumbai, 400012, Maharashtra, India
World J Surg 36:864-71. 2012..The aim of this study was to assess the role of neoadjuvant imatinib in redefining treatment for gastrointestinal stromal tumors (GISTs)...
Outcomes of resection for rectal cancer in India: the impact of the double stapling techniqueShailesh V Shrikhande
Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
World J Surg Oncol 5:35. 2007..However studies using this technique and their results, in the Indian scenario, as well as the rest of Asia, have been few and far between...
Complications as indicators of quality assurance after 401 consecutive colorectal cancer resections: the importance of surgeon volume in developing colorectal cancer units in IndiaGuruprasad S Shetty
Department of Gastrointestinal Surgical Oncology, Tata Memorial Centre, Mumbai, India
World J Surg Oncol 10:15. 2012..We evaluated the data of the senior author to better define the requirements that would enable development of specialized units in a country where colorectal cancer burden is increasing...
Systematic review: should routine resection of the extra-hepatic bile duct be performed in gallbladder cancer?Parul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Saudi J Gastroenterol 16:161-7. 2010..Complete surgical resection is associated with improved outcomes in gallbladder cancer. Whether the extra-hepatic bile duct (EHBD) should be routinely excised for gallbladder cancer is unclear...
D2 lymphadenectomy for gastric cancer in Tata Memorial Hospital: Indian data can now be incorporated in future international trialsShailesh V Shrikhande
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Dig Surg 23:192-7. 2006..While mortality rates after radical gastrectomy have decreased, there is considerable morbidity after D2 lymphadenectomy. In this study, we assessed the perioperative results of D2 gastrectomy for gastric cancer...
The vascular stapler in uncinate process division during pancreaticoduodenectomy: technical considerations and resultsMelroy A D'souza
Department of GI and HPB Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Dig Surg 27:175-81. 2010..Our aim is to discuss our technique and the peri-operative outcomes with the use of the linear vascular stapler for division of the uncinate process during PD...
Evolution of pancreatoduodenectomy in a tertiary cancer center in India: improved results from service reconfigurationShailesh V Shrikhande
Department of Gastrointestinal and Hepato Pancreato Biliary Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
Pancreatology 13:63-71. 2013..Over the years, refinements in technique of pancreatoduodenectomy (PD) may have improved outcomes. No data is available from India, South-Central, or South West Asia to assess the impact of these refinements...
The gray zone between postpancreaticoduodenectomy collections and pancreatic fistulaGeorge Barreto
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Pancreas 37:422-5. 2008..There is a recent report questioning the ISGPF criteria's ability to accurately predict pancreatic anastomotic failure and outlining new criteria. We decided to validate both proposed criteria based on our experience...
Hepatic resection for metastasis from adenoid cystic carcinoma of parotid glandSajid S Qureshi
Department of Surgical Gastroenterology, Tata Memorial Hospital, Mumbai-400 012, India
Indian J Gastroenterol 24:29-30. 2005..We present a 30-year-old woman with solitary liver metastasis from an adenoid cystic carcinoma of the parotid gland, which had been surgically treated 10 years ago. The patient underwent successful resection of this metastasis...
Pancreatic anastomoses after pancreaticoduodenectomy: do we need further studies?Shailesh V Shrikhande
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Dr Ernest Borges Marg, Parel, Mumbai, 400 012, India
World J Surg 29:1642-9. 2005....
Isolated gall bladder metastasis from renal cell carcinomaDurgatosh Pandey
Department of Surgical Oncology, Tata Memorial Hospital, Mumbai - 400 012, India
Indian J Gastroenterol 25:161-2. 2006..He underwent cholecystectomy and frozen section revealed the metastatic tumor. Sixteen months later, the patient is free of disease...
Perioperative outcomes after ultra low anterior resection in the era of neoadjuvant chemoradiotherapyShailesh V Shrikhande
Department of Gastrointestinal and Hepato Pancreato Biliary Surgical Oncology, Tata Memorial Centre, Dr Ernest Borges Marg, Parel, Mumbai, 400 012, India
Indian J Gastroenterol 32:90-7. 2013..Data on perioperative outcomes of sphincter preserving ultra low anterior resections (ULAR) following neoadjuvant chemoradiotherapy (NA-CTRT) is sparsely reported in literature...
Hepatocellular carcinoma recurring as isolated endobronchial metastasis 8 years after primary surgeryNilendu C Purandare
Bio Imaging Unit, Tata Memorial Hospital, Mumbai, India
J Thorac Imaging 24:147-9. 2009..Indolent course of the primary hepatocellular carcinoma and the solitary site of endobronchial recurrence prompted a surgical resection of the endobronchial metastasis...
Indigenous and austere technique of self-retaining abdominal retraction for facilitating surgical exposureSajid S Qureshi
Department of Surgical Oncology, Tata Memorial Hospital, Ernest Borges Road, Parel, Bombay, India
J Surg Oncol 93:420-1. 2006..However, these retractors are complex and unwieldy, causing hindrance in the movement of the surgeon. We describe a technique of self-retaining abdominal retraction that is simple and also obviates the need for an additional assistant...
Primary neuroendocrine carcinoma presenting as mesenteric cystAjay S Punpale
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Indian J Gastroenterol 26:137-8. 2007..Surgical resection is the best treatment modality, with a chance of cure. We present a 65-year-old man with large mesenteric cyst and absence of bowel involvement. Histology showed a well-differentiated neuroendocrine tumor...
Small intestinal tumoursSavio George Barreto
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
J Coll Physicians Surg Pak 19:459-63. 2009..Small bowel consciousness is crucial in diagnosing and treating these tumours. This review aims to increase awareness of small bowel tumours in terms of epidemiology, diagnosis and treatment...
Current status of laparoscopic surgery in gastrointestinal malignanciesParul J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Indian J Surg 70:261-4. 2008..Neither of these concerns have stood the test of time. Laparoscopy is being used increasingly in oncological surgery both for staging and respective surgery. This article outlines the present use of laparoscopy in GI cancer surgery...
Extended pancreatectomy for pancreatic cancersParul J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary, Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Indian J Surg 71:2-5. 2009..This review outlines the rationale for and technique of extended resections in pancreatic cancer...
Adjuvant radiation therapy in gall bladder cancers: 10 years experience at Tata Memorial HospitalUmesh M Mahantshetty
Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, India
J Cancer Res Ther 2:52-6. 2006..With an aim to evaluate the natural history of gall bladder cancers, role of radiation therapy (RT) and prognostication, a retrospective analysis was undertaken...
Anorectal melanoma: a large clinicopathologic study from IndiaGanesh Das
Gastrointestinal Service, Department of Surgical Oncology, Tata Memorial Hospital, Santacruz-W, Mumbai, India
Int Surg 88:21-4. 2003..5 months. A subset of patients with localized disease can benefit from radical surgery. In patients with large bulky localized disease, radical surgery provides better palliation than local excision...
Vitamin D3 in operable periampullary and pancreatic cancer: perioperative outcomes in a pilot study assessing safetySavio G Barreto
Pancreas 36:315-7. 2008
Defining the completeness of surgery for early gallbladder cancerSavio George Barreto
Ann Surg 248:896; author reply 896-7. 2008
