Research Topics
| Dominick E ShawSummaryCountry: UK Publications
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Detail Information
Publications
Association between neutrophilic airway inflammation and airflow limitation in adults with asthmaDominick E Shaw
Institute for Lung Health, Department of Respiratory Medicine and Thoracic Surgery, Glenfield Hospital, Leicester LE3 9QP, UK
Chest 132:1871-5. 2007..Chronic inflammation is assumed to be important, although there is limited and contradictory information about the relationship between airway inflammation and postbronchodilator FEV1...
The use of exhaled nitric oxide to guide asthma management: a randomized controlled trialDominick E Shaw
Institute for Lung Health, Department of Respiratory Medicine and Thoracic Surgery, Glenfield Hospital, Leicester, United Kingdom
Am J Respir Crit Care Med 176:231-7. 2007..Current asthma guidelines recommend adjusting antiinflammatory treatment on the basis of the results of lung function tests and symptom assessment, neither of which are closely associated with airway inflammation...
Evidence of a role of tumor necrosis factor alpha in refractory asthmaMike A Berry
Institute for Lung Health, University Hospital of Leicester National Health Service Trust, Glenfield Hospital, Leicester, United Kingdom
N Engl J Med 354:697-708. 2006..08 to 0.55; P=0.01). CONCLUSIONS: Patients with refractory asthma have evidence of up-regulation of the TNF-alpha axis. (ClinicalTrials.gov number, NCT00276029.)...
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthmaMike Berry
Institute for Lung Health, Glenfield Hospital, Leicester LE3 9QP, UK
Thorax 62:1043-9. 2007..However, little is known about the underlying airway immunopathology and there are no data from placebo-controlled studies examining the effect of inhaled corticosteroids...
Inflammometry to assess airway diseasesIan D Pavord
Department of Respiratory Medicine, Allergy and Thoracic Surgery, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester LE3 9QP, UK
Lancet 372:1017-9. 2008
