Hugh P Shanahan

Summary

Country: UK

Publications

  1. pmc Identifying DNA-binding proteins using structural motifs and the electrostatic potential
    Hugh P Shanahan
    EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 32:4732-41. 2004
  2. ncbi request reprint Amino acid architecture and the distribution of polar atoms on the surfaces of proteins
    H P Shanahan
    Department of Computer Science, Royal Holloway College, University of London, Egham, Surrey, TW20 0EX, England, UK
    Biopolymers 78:318-28. 2005
  3. pmc Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins
    Susan Jones
    EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 31:7189-98. 2003
  4. ncbi request reprint An examination of the conservation of surface patch polarity for proteins
    H P Shanahan
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Bioinformatics 20:2197-204. 2004

Detail Information

Publications4

  1. pmc Identifying DNA-binding proteins using structural motifs and the electrostatic potential
    Hugh P Shanahan
    EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 32:4732-41. 2004
    ..Similar true positive fractions are achieved for the HhH and HLH motifs. We see evidence of wide evolutionary diversity for DNA-binding proteins with an HTH motif, and much smaller diversity for those with an HhH or HLH motif...
  2. ncbi request reprint Amino acid architecture and the distribution of polar atoms on the surfaces of proteins
    H P Shanahan
    Department of Computer Science, Royal Holloway College, University of London, Egham, Surrey, TW20 0EX, England, UK
    Biopolymers 78:318-28. 2005
    ....
  3. pmc Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins
    Susan Jones
    EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 31:7189-98. 2003
    ..This method was used to make predictions for a data set of 56 non-homologous DNA-binding proteins. Correct predictions made for 68% of the data set...
  4. ncbi request reprint An examination of the conservation of surface patch polarity for proteins
    H P Shanahan
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Bioinformatics 20:2197-204. 2004
    ..This is computed for a set of 28 monomeric proteins and their homologues. The resulting distributions are compared with a set of randomized sequences, with the same residue content...