Research Topics
| Robert WilsonSummaryAffiliation: Royal Brompton Hospital Country: UK Publications
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Detail Information
Publications
A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomesRobert Wilson
Royal Brompton Hospital, London, England
Clin Ther 24:639-52. 2002..Gemifloxacin is an enhanced-affinity quinolone with potent activity against lower respiratory tract pathogens...- Oral gemifloxacin once daily for 5 days compared with sequential therapy with i.v. ceftriaxone/oral cefuroxime (maximum of 10 days) in the treatment of hospitalized patients with acute exacerbations of chronic bronchitisR Wilson
Royal Brompton Hospital, London, U K
Respir Med 97:242-9. 2003..A 5-day course of oral gemifloxacin was shown by this study to be at least equivalent to sequential i.v. ceftriaxone/cefuroxime axetil (for up to 10 days) in patients with AECB who require hospital treatment... - Short-term and long-term outcomes of moxifloxacin compared to standard antibiotic treatment in acute exacerbations of chronic bronchitisRobert Wilson
Royal Brompton Hospital, London, UK
Chest 125:953-64. 2004..To compare the effectiveness of oral moxifloxacin with standard antibiotic therapy in acute exacerbation of chronic bronchitis (AECB)... 
Moxifloxacin versus amoxicillin/clavulanic acid in outpatient acute exacerbations of COPD: MAESTRAL resultsRobert Wilson
Host Defence Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
Eur Respir J 40:17-27. 2012..The MAESTRAL study showed that moxifloxacin was as effective as amoxicillin/clavulanic acid in the treatment of outpatients with AECOPD. Both therapies were well tolerated...- Newer fluoroquinolones in the treatment of acute exacerbations of COPDAmit Patel
Royal Brompton Hospital, London, UK
Int J Chron Obstruct Pulmon Dis 1:243-50. 2006..Recent antibiotic trials have compared fluoroquinolones with "standard" antibiotics and found, in the main, longer exacerbation-free intervals and better bacterial eradication rates in those treated with fluoroquinolones... - A novel study design for antibiotic trials in acute exacerbations of COPD: MAESTRAL methodologyRobert Wilson
Host Defence Unit, Royal Brompton Hospital, London, England, UK
Int J Chron Obstruct Pulmon Dis 6:373-83. 2011..Patients are stratified according to oral corticosteroid use to control their effect across antibiotic treatment arms. Secondary endpoints include quality of life, symptom assessments and health care resource use... 
Respiratory infection in noncystic fibrosis bronchiectasisZaid Zoumot
Host Defence Unit, Royal Brompton Hospital, London, UK
Curr Opin Infect Dis 23:165-70. 2010..We highlight some of the main developments in the investigation and management of bronchiectasis, a condition causing susceptibility to airway infections and in more severe cases chronic bronchial suppuration...- Pulmonary hypertension in patients with bronchiectasis: prognostic significance of CT signsAnand Devaraj
Department of Radiology, Royal Brompton Hospital, Sydney St, London, SW3 6NP, UK
AJR Am J Roentgenol 196:1300-4. 2011..The purpose of this study was to evaluate the association between pulmonary hypertension estimated with CT and outcome among patients with bronchiectasis... - Ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis: a phase II randomised studyRobert Wilson
Royal Brompton Hospital, London
Eur Respir J 41:1107-15. 2013..Ciprofloxacin DPI 32.5 mg twice daily for 28 days was well tolerated and achieved significant reductions in total bacterial load compared with placebo in subjects with non-cystic fibrosis bronchiectasis... - Pharmacotherapy for bronchiectasisMichael R Loebinger
Royal Brompton Hospital, Host Defence Unit, Fulham Road, London, SW3 6NP, UK
Expert Opin Pharmacother 8:3183-93. 2007..This article discusses the management of bronchiectasis with particular reference to the pathophysiological processes involved in the condition. It then looks at the available evidence supporting such a management plan... - In vitro models of infection I--human respiratory tissue organ cultureAndrew M Middleton
Department of Microbiology, Royal Brompton Hospital, Host Defense Unit, Imperial College School of Science, Technology and Medicine, National Heart and Lung Institute, London, United Kingdom
Methods Mol Med 71:277-95. 2003 - MOSAIC acronymRobert Wilson
Chest 126:1708. 2004 - Short course of antibiotic treatment in acute exacerbations of COPDRobert Wilson
Thorax 63:390-2. 2008 - Endothelial dysfunction in patients with recent myocardial infarction and hyperhomocysteinaemia: effects of vitamin supplementationStanley Chia
Department of Cardiology, National Heart Centre, 17 Hospital Avenue, Singapore 168752, Republic of Singapore
Clin Sci (Lond) 108:65-72. 2005..This endothelial vasomotor dysfunction is unaltered by vitamin supplementation... - Bacteria and airway inflammation in chronic obstructive pulmonary disease: more evidenceRobert Wilson
Am J Respir Crit Care Med 172:147-8. 2005 - Multiple simultaneous complications of acute otitis media in a child diagnosed with chronic granulomatous disease: a case reportRobert Wilson
Department of Surgery, Division of Otolaryngology, University of Kentucky College of Medicine, 800 Rose St, Lexington, KY 40536 0298, USA
Ear Nose Throat J 87:271-2, 279. 2008..The presented case should encourage physicians to investigate the possibility of an underlying immunodeficiency when treating patients with multiple simultaneous complications of acute otitis media...