S G Wannamethee

Summary

Affiliation: Royal Free and University College Medical School
Country: UK

Publications

  1. ncbi Alcohol, coronary heart disease and stroke: an examination of the J-shaped curve
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, London, UK
    Neuroepidemiology 17:288-95. 1998
  2. ncbi Physical activity and mortality in older men with diagnosed coronary heart disease
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Circulation 102:1358-63. 2000
  3. ncbi HDL-Cholesterol, total cholesterol, and the risk of stroke in middle-aged British men
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Stroke 31:1882-8. 2000
  4. ncbi Physical activity, metabolic factors, and the incidence of coronary heart disease and type 2 diabetes
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, England
    Arch Intern Med 160:2108-16. 2000
  5. ncbi Physical activity and the prevention of stroke
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, UK
    J Cardiovasc Risk 6:213-6. 1999
  6. ncbi Nonfasting serum glucose and insulin concentrations and the risk of stroke
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, England
    Stroke 30:1780-6. 1999
  7. ncbi Type of alcoholic drink and risk of major coronary heart disease events and all-cause mortality
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, London, England
    Am J Public Health 89:685-90. 1999
  8. ncbi Serum true insulin concentration and the risk of clinical non-insulin dependent diabetes during long-term follow-up
    I J Perry
    Department of Primary Care and Population Sciences, The Royal Free Hospital School of Medicine, London, UK
    Int J Epidemiol 28:735-41. 1999
  9. ncbi Smoking as a modifiable risk factor for type 2 diabetes in middle-aged men
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, U K
    Diabetes Care 24:1590-5. 2001
  10. ncbi Prospective study of circulating soluble CD40 ligand concentrations and the incidence of cardiovascular disease in a nested prospective case-control study of older men and women
    B J Jefferis
    Department of Primary Care and Population Health, UCL Medical School, Rowland Hill Street, London, UK
    J Thromb Haemost 9:1452-9. 2011

Detail Information

Publications45

  1. ncbi Alcohol, coronary heart disease and stroke: an examination of the J-shaped curve
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, London, UK
    Neuroepidemiology 17:288-95. 1998
    ..The public health message should emphasise the potential harm of heavier drinking rather than concentrating on the possible benefits of light drinking...
  2. ncbi Physical activity and mortality in older men with diagnosed coronary heart disease
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Circulation 102:1358-63. 2000
    ..We have studied the relations between physical activity, types of physical activity, and changes in physical activity and all-cause mortality in men with established coronary heart disease (CHD)...
  3. ncbi HDL-Cholesterol, total cholesterol, and the risk of stroke in middle-aged British men
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Stroke 31:1882-8. 2000
    ..The purpose of this study was to examine the relation between serum HDL cholesterol and total cholesterol and risk of stroke...
  4. ncbi Physical activity, metabolic factors, and the incidence of coronary heart disease and type 2 diabetes
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, England
    Arch Intern Med 160:2108-16. 2000
    ..To examine the role of nonfasting serum insulin level and components of the insulin resistance syndrome in the relationship between physical activity and the incidence of coronary heart disease and type 2 diabetes...
  5. ncbi Physical activity and the prevention of stroke
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, UK
    J Cardiovasc Risk 6:213-6. 1999
    ..Sporting (vigorous) activity does not appear to be essential to achieve this benefit. Moderate levels of physical activity may be sufficient to achieve a significant reduction in stroke risk and overall cardiovascular risk...
  6. ncbi Nonfasting serum glucose and insulin concentrations and the risk of stroke
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, England
    Stroke 30:1780-6. 1999
    ..We have examined the relationship between established diabetes, nonfasting serum glucose and serum insulin concentrations, and subsequent risk of stroke...
  7. ncbi Type of alcoholic drink and risk of major coronary heart disease events and all-cause mortality
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, London, England
    Am J Public Health 89:685-90. 1999
    ..This study examined the effects of beer, spirits, and wine drinking on coronary heart disease (CHD) events (fatal and nonfatal) and all-cause mortality...
  8. ncbi Serum true insulin concentration and the risk of clinical non-insulin dependent diabetes during long-term follow-up
    I J Perry
    Department of Primary Care and Population Sciences, The Royal Free Hospital School of Medicine, London, UK
    Int J Epidemiol 28:735-41. 1999
    ..Using a specific assay, we have addressed the hypothesis that an elevation of serum true insulin concentration, reflecting insulin resistance, is an early event in the pathogenesis of NIDDM...
  9. ncbi Smoking as a modifiable risk factor for type 2 diabetes in middle-aged men
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, U K
    Diabetes Care 24:1590-5. 2001
    ..To examine the effects of cigarette smoking, giving up smoking, and primary or secondary pipe or cigar smoking on the risk of type 2 diabetes...
  10. ncbi Prospective study of circulating soluble CD40 ligand concentrations and the incidence of cardiovascular disease in a nested prospective case-control study of older men and women
    B J Jefferis
    Department of Primary Care and Population Health, UCL Medical School, Rowland Hill Street, London, UK
    J Thromb Haemost 9:1452-9. 2011
    ..CD40 ligand(CD40L) is implicated in atherosclerotic plaque formation...
  11. ncbi Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men
    S G Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Royal Free Campus, London NW3 2PF, UK
    J Thromb Haemost 7:1605-11. 2009
    ....
  12. ncbi Assessing prediction of diabetes in older adults using different adiposity measures: a 7 year prospective study in 6,923 older men and women
    S G Wannamethee
    Department of Primary Care and Population Health, University College London Medical School, Hampstead Campus, Rowland Hill St, London NW3 2PF, UK
    Diabetologia 53:890-8. 2010
    ..The aim of this study was to examine whether waist circumference (WC) or WHR improve diabetes prediction beyond body mass index in older men and women, and to define optimal cut-off points...
  13. ncbi Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women's Heart Health Study
    S G Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Hampstead Campus, Rowland Hill St, London, NW3 2PF, UK
    Diabetologia 55:80-7. 2012
    ....
  14. ncbi The value of gamma-glutamyltransferase in cardiovascular risk prediction in men without diagnosed cardiovascular disease or diabetes
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Atherosclerosis 201:168-75. 2008
    ..We have examined the relationship between gamma-glutamyltransferase (GGT) and major coronary heart disease (CHD) and stroke events and cardiovascular mortality in men free of cardiovascular disease (CVD)...
  15. ncbi Extent of social inequalities in disability in the elderly: results from a population-based study of British men
    Sheena E Ramsay
    Division of Population Health, University College London, St George s University of London, London, UK
    Ann Epidemiol 18:896-903. 2008
    ..Little is known about social inequalities in disability in the elderly. We examined the extent and determinants of socioeconomic inequalities in disability and functional limitation in elderly men in Britain...
  16. ncbi Cotinine-assessed second-hand smoke exposure and risk of cardiovascular disease in older adults
    B J Jefferis
    UCL Department of Primary Care and Population Health, UCL Medical School, London, UK
    Heart 96:854-9. 2010
    ..To examine whether second-hand smoke (SHS) exposure measured by serum cotinine is associated with increased coronary heart disease (CHD) and stroke risk among contemporary older British adults...
  17. ncbi Socioeconomic inequalities in coronary heart disease risk in older age: contribution of established and novel coronary risk factors
    S E Ramsay
    Division of Population Health, UCL, London, UK
    J Thromb Haemost 7:1779-86. 2009
    ..Little is also known about the contributions that novel coronary risk factors (particularly inflammatory/hemostatic markers) make to socioeconomic inequalities in CHD...
  18. ncbi Alcohol consumption and the incidence of type II diabetes
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    J Epidemiol Community Health 56:542-8. 2002
    ..This study examines the relation between alcohol and type II diabetes and the possible mediating effects of HDL-cholesterol and serum insulin...
  19. ncbi Inter-relationships of interleukin-6, cardiovascular risk factors and the metabolic syndrome among older men
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    J Thromb Haemost 5:1637-43. 2007
    ..Interleukin-6 (IL-6) has been implicated in the development of cardiovascular disease. We have examined the relationship between plasma IL-6 and insulin resistance, and metabolic, inflammatory and hemostatic markers...
  20. ncbi Is socioeconomic position related to the prevalence of metabolic syndrome?: influence of social class across the life course in a population-based study of older men
    Sheena E Ramsay
    Division of Population Health, University College London, London, UK
    Diabetes Care 31:2380-2. 2008
    ..To examine whether adult social class and childhood social class are related to metabolic syndrome in later life, independent of adult behavioral factors...
  21. ncbi Variability of angina symptoms and the risk of major ischemic heart disease events
    F C Lampe
    Cardiovascular Research Unit, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Epidemiol 153:1173-82. 2001
    ..In middle-aged men, exertional chest pain is a strong indicator of major coronary risk but frequently appears transient in the longer term. Persistently reported symptoms are associated with severe disease and a poor prognosis...
  22. ncbi Are social inequalities in mortality in Britain narrowing? Time trends from 1978 to 2005 in a population-based study of older men
    S E Ramsay
    Department of Primary Care and Population Sciences, Royal Free Hospital and University College Medical School, London, UK
    J Epidemiol Community Health 62:75-80. 2008
    ..To examine whether social inequalities in all-cause and coronary heart disease (CHD) mortality in Britain have reduced between 1978 and 2005...
  23. ncbi Are childhood socio-economic circumstances related to coronary heart disease risk? Findings from a population-based study of older men
    Sheena E Ramsay
    Department of Primary Care and Population Sciences, Royal Free Hospital and University College Medical School, Rowland Hill Street, London, UK
    Int J Epidemiol 36:560-6. 2007
    ..We examined the extent to which childhood socio-economic circumstances are related to the risk of coronary heart disease (CHD) in older British men, taking account of adult social class and behavioural risk factors...
  24. ncbi Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women
    B J Jefferis
    Department Primary Care and Population Health, UCL Medical School, Rowland Hill St, NW3 2PF, London, UK
    Atherosclerosis 208:550-6. 2010
    ..Therefore we investigate associations between SHS exposure and CHD risk factors, to clarify how SHS exposure may raise risk of CHD...
  25. ncbi Associations of adiponectin with metabolic and vascular risk parameters in the British Regional Heart Study reveal stronger links to insulin resistance-related than to coronory heart disease risk-related parameters
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Int J Obes (Lond) 31:1089-98. 2007
    ..We examined the relationship between adiponectin and insulin resistance, metabolic, inflammatory and haemostatic risk factors and hepatic function...
  26. ncbi Measuring the prevalence of disease in middle-aged British men
    M Walker
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Royal Free Campus, London
    J R Coll Physicians Lond 33:351-8. 1999
    ..To identify and validate a measure of disease prevalence in a town or other subpopulation for the purpose of estimating variations in morbidity and health care needs between groups...
  27. ncbi Geographic variation in incidence of coronary heart disease in Britain: the contribution of established risk factors
    R W Morris
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK
    Heart 86:277-83. 2001
    ..To determine the extent to which geographic variation in the incidence of major coronary heart disease (CHD) in Great Britain may be explained by established risk factors...
  28. ncbi Weight change, body weight and mortality: the impact of smoking and ill health
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, Rowland Hill St, London NW3 2PF, UK
    Int J Epidemiol 30:777-86. 2001
    ....
  29. ncbi Longitudinal associations of socioeconomic position in childhood and adulthood with decline in lung function over 20 years: results from a population-based cohort of British men
    Sheena E Ramsay
    Department of Primary Care and Population Health, UCL, London, UK
    Thorax 66:1058-64. 2011
    ..The aim of this study was to investigate the associations between socioeconomic position both in adulthood and childhood with changes in lung function over a 20-year period...
  30. ncbi Cardiovascular disease incidence and mortality in older men with diabetes and in men with coronary heart disease
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, UK
    Heart 90:1398-403. 2004
    ..To examine the relation of diabetes and coronary heart disease (CHD; myocardial infarction (MI) or angina) to the incidence of major CHD and stroke events and total mortality...
  31. ncbi Social engagement and the risk of cardiovascular disease mortality: results of a prospective population-based study of older men
    Sheena Ramsay
    Department of Primary Care and Population Sciences, University College London, London, UK
    Ann Epidemiol 18:476-83. 2008
    ....
  32. ncbi Physical activity and risk of cancer in middle-aged men
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, NW3 2PF, UK
    Br J Cancer 85:1311-6. 2001
    ..Moderately-vigorous or vigorous levels involving sporting activities are required to achieve such benefit...
  33. ncbi Insulin resistance, haemostatic and inflammatory markers and coronary heart disease risk factors in Type 2 diabetic men with and without coronary heart disease
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London, NW3 2PF, UK
    Diabetologia 47:1557-65. 2004
    ..We have examined markers of haemostasis and inflammation in men with diabetes, coronary heart disease (CHD) or both, and assessed their associations with insulin resistance in men with Type 2 diabetes...
  34. ncbi Alcohol intake in middle age and risk of cardiovascular disease and mortality: accounting for intake variation over time
    J R Emberson
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Am J Epidemiol 161:856-63. 2005
    ..The findings suggest that considerable caution may be needed before any recommendations regarding acceptable limits of alcohol consumption are made...
  35. ncbi Alcohol intake and mortality in middle aged men with diagnosed coronary heart disease
    A G Shaper
    Department of Primary Care and Population Sciences, Royal Free and University College Medical Schools, Rowland Hill Street, London NW3 2PF, UK
    Heart 83:394-9. 2000
    ..To examine the effects of alcohol on risk of mortality from coronary heart disease (CHD), cardiovascular disease, and all causes in men with established CHD...
  36. ncbi The relations of body composition and adiposity measures to ill health and physical disability in elderly men
    Sheena E Ramsay
    Department of Primary Care and Population Sciences, Royal Free Hospital and University College Medical School, London, United Kingdom
    Am J Epidemiol 164:459-69. 2006
    ..Prevention of weight gain with increasing age is likely to reduce morbidity and disability among older men...
  37. ncbi Taking up regular drinking in middle age: effect on major coronary heart disease events and mortality
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, UK
    Heart 87:32-6. 2002
    ..To examine effects of taking up regular drinking by middle aged non-drinkers and occasional drinkers on major coronary heart disease events and total mortality...
  38. ncbi Missed opportunities for secondary prevention of cerebrovascular disease in elderly British men from 1999 to 2005: a population-based study
    Sheena E Ramsay
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, UCL Hampstead Campus, Rowland Hill Street, London NW3 2PF, UK
    J Public Health (Oxf) 29:251-7. 2007
    ..We examined patterns in medication use for secondary prevention of cerebrovascular disease in older British men from 1999 to 2005, and investigated socio-demographic and disease-related influences on medication use...
  39. ncbi Alcohol and adiposity: effects of quantity and type of drink and time relation with meals
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Int J Obes (Lond) 29:1436-44. 2005
    ..It has been suggested that the effects of alcohol on body weight and fat distribution may be influenced by the quantity and type of drink and may differ according to whether the alcohol is consumed with meals or not...
  40. ncbi The metabolic syndrome and cardiovascular risk in the British Regional Heart Study
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, UK
    Int J Obes (Lond) 32:S25-9. 2008
    ..To evaluate the metabolic syndrome as an overall risk assessment tool for cardiovascular disease (CVD) and diabetes in middle-aged British men...
  41. ncbi Pipe and cigar smoking and major cardiovascular events, cancer incidence and all-cause mortality in middle-aged British men
    A G Shaper
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, 8 Wentworth Hall, The Ridgeway, Mill Hill, London NW7 1RJ, UK
    Int J Epidemiol 32:802-8. 2003
    ..Pipe and cigar smoking are still regarded by many as less hazardous to health than cigarette smoking...
  42. ncbi Prospective study of seasonal patterns in hemostatic factors in older men and their relation to excess winter coronary heart disease deaths
    M A Ghebre
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    J Thromb Haemost 10:352-8. 2012
    ..The potential contributions of these hemostatic activation measures to excess winter mortality are unknown...
  43. ncbi Physical activity in the prevention of cardiovascular disease: an epidemiological perspective
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, England
    Sports Med 31:101-14. 2001
    ..Taking up regular light or moderate physical activity in middle or older age confers significant benefit for CVD and all-cause mortality...
  44. ncbi Birthweight of offspring and paternal insulin resistance and paternal diabetes in late adulthood: cross sectional survey
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, Rowland Hill St, NW3 2PF London, UK
    Diabetologia 47:12-8. 2004
    ..To confirm this we examined the association between offspring birthweight and paternal insulin resistance and diabetes in late adulthood...
  45. ncbi Serum uric acid is not an independent risk factor for coronary heart disease
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Curr Hypertens Rep 3:190-6. 2001
    ..This review finds little support for an independent causal role for serum uric acid in the development of coronary heart disease...