Research Topics
| Holger A VolkSummaryAffiliation: Royal Veterinary College Country: UK Publications
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Detail Information
Publications
Neuromuscular disorders in the cat: clinical approach to weaknessHolger A Volk
Department of Veterinary Clinical Sciences, Royal Veterinary College, Hatfield, UK
J Feline Med Surg 13:837-49. 2011..The evidence base for the treatment of feline neuromuscular diseases remains very limited...
The efficacy and tolerability of levetiracetam in pharmacoresistant epileptic dogsHolger A Volk
Department of Veterinary Clinical Sciences, Neurology, Royal Veterinary College, Hatfield, UK
Vet J 176:310-9. 2008..Levetiracetam was well tolerated by all dogs and sedation was the only side-effect reported in just one of the 14 dogs...- Surgical treatment of an intracranial epidermoid cyst in a dogSteven De Decker
Department of Veterinary Clinical Sciences, Royal Veterinary College, University of London, England
Vet Surg 41:766-71. 2012..To report challenges and complications associated with surgical intracranial epidermoid cyst removal from the fourth ventricle of a dog... 
Increase in cerebellar volume in Cavalier King Charles Spaniels with Chiari-like malformation and its role in the development of syringomyeliaThomas A Shaw
Department of Veterinary Clinical Sciences, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
PLoS ONE 7:e33660. 2012....- Distribution of syringomyelia along the entire spinal cord in clinically affected Cavalier King Charles SpanielsShenja Loderstedt
Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, Hawkshead Lane, North Mymns, Hatfield, Hertfordshire AL9 7TA, UK
Vet J 190:359-63. 2011..MRI restricted to the cervical region may underestimate the extent of SM and the severity of the disease process in the majority of dogs... - Behavioral changes in dogs associated with the development of idiopathic epilepsyNadia Shihab
Department of Veterinary Clinical Sciences, Royal Veterinary College, Hertfordshire, UK
Epilepsy Behav 21:160-7. 2011..The aim of the study was to demonstrate behavioral changes with the development of epilepsy in dogs, a species proposed as a naturally occurring animal model for human epilepsy... - Changes over time in craniocerebral morphology and syringomyelia in cavalier King Charles spaniels with Chiari-like malformationColin J Driver
Department of Veterinary Clinical Sciences, Royal Veterinary College, London, UK
BMC Vet Res 8:215. 2012..A retrospective morphometric analysis was undertaken in 12 CKCS with CM for which repeat magnetic resonance images were available without surgical intervention... - Imaging diagnosis--spinal cord hemangioma in two dogsPhilip Jull
Department of Veterinary Clinical Sciences, Royal Veterinary College, London, UK
Vet Radiol Ultrasound 52:653-7. 2011..In T1w images, there was a large isointense centre with a relatively small hyperintense periphery. Such characteristics should prioritize hemangioma as a consideration in a progressive myelopathy due to an intramedullary mass... - Questionnaire-based behaviour analysis of Cavalier King Charles spaniels with neuropathic pain due to Chiari-like malformation and syringomyeliaLynda Rutherford
Department of Veterinary Clinical Sciences, Royal Veterinary College, Hatfield, UK
Vet J 194:294-8. 2012..50). Severity of NeP was positively associated with certain fear-associated behaviour and with decreased owner-perceived QoL. Thus, neurobehavioural changes should be considered in the management of NeP in CKCS with CM/SM... - Intervertebral disk width in dogs with and without clinical signs of disk associated cervical spondylomyelopathySteven De Decker
Royal Veterinary College, University of London, Department of Veterinary Clinical Sciences, Hawkshead Lane, North Mymms AL97TA, UK
BMC Vet Res 8:126. 2012.... - Treatment of hydrocephalus with ventriculoperitoneal shunting in twelve dogsNadia Shihab
Department of Veterinary Clinical Sciences, Royal Veterinary College, North Mymms, UK
Vet Surg 40:477-84. 2011..To report use of ventriculoperitoneal shunt in dogs for management of hydrocephalus for which no cause could be identified... - Imaging the cranial nervesAndrew T Parry
Department of Veterinary Clinical Sciences, Royal Veterinary College, University of London, UK
Vet Radiol Ultrasound 52:S32-41. 2011..The function and anatomy of the CN in the dog are reviewed and selected examples of lesions affecting the CN are illustrated... - Evaluation of cerebrospinal fluid in Cavalier King Charles Spaniel dogs diagnosed with Chiari-like malformation with or without concurrent syringomyeliaDanielle E Whittaker
Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL97TA, UK
J Vet Diagn Invest 23:302-7. 2011..Development of syringomyelia is accompanied by alterations in cerebrospinal fluid composition. The pathogenesis of syringomyelia has not been fully elucidated; therefore, the exact origin of cerebrospinal fluid changes remains unclear... - Prophylactic treatment with levetiracetam after status epilepticus: lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in ratsClaudia Brandt
Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine, Bunteweg 17, D 30559 Hannover, Germany
Neuropharmacology 53:207-21. 2007..These data do not support the idea that administration of LEV after SE prevents or reduces the long-term alterations developing after such brain insult in rats... - Antiepileptic drug-resistant rats differ from drug-responsive rats in hippocampal neurodegeneration and GABA(A) receptor ligand binding in a model of temporal lobe epilepsyHolger A Volk
Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Hannover, Germany
Neurobiol Dis 21:633-46. 2006..The present data indicate that neurodegeneration and associated GABA(A) receptor changes in the dentate gyrus are critically involved in the mechanisms underlying refractoriness of seizures in TLE... - Multidrug resistance in epilepsy: rats with drug-resistant seizures exhibit enhanced brain expression of P-glycoprotein compared with rats with drug-responsive seizuresHolger A Volk
Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover, Hannover, Germany
Brain 128:1358-68. 2005.... - Striking differences in individual anticonvulsant response to phenobarbital in rats with spontaneous seizures after status epilepticusClaudia Brandt
Department of Pharmacology, Toxicology, and Pharmacy, School of Veterinary Medicine, Hannover, Germany
Epilepsia 45:1488-97. 2004.... - Pharmacoresistance and expression of multidrug transporter P-glycoprotein in kindled ratsHeidrun Potschka
Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine, Bunteweg 17, D 30559 Hannover, Germany
Neuroreport 15:1657-61. 2004..The data indicate that P-glycoprotein expression levels in the kindled focus have a critical impact on the anticonvulsant response to antiepileptic drugs...