Roger K W Smith

Summary

Affiliation: Royal Veterinary College
Country: UK

Publications

  1. ncbi The influence of ageing and exercise on tendon growth and degeneration--hypotheses for the initiation and prevention of strain-induced tendinopathies
    R K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK
    Comp Biochem Physiol A Mol Integr Physiol 133:1039-50. 2002
  2. ncbi The effect of early training and the adaptation and conditioning of skeletal tissues
    Roger K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Vet Clin North Am Equine Pract 24:37-51. 2008
  3. ncbi Gene expression markers of tendon fibroblasts in normal and diseased tissue compared to monolayer and three dimensional culture systems
    Sarah E Taylor
    Department of Veterinary Clinical Science, University of Liverpool, Neston, South Wirral, UK
    BMC Musculoskelet Disord 10:27. 2009
  4. ncbi Mesenchymal stem cell therapy for equine tendinopathy
    Roger K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, North Mymms, Hatfield, Hertfordshire, UK
    Disabil Rehabil 30:1752-8. 2008
  5. ncbi Harnessing the stem cell for the treatment of tendon injuries: heralding a new dawn?
    R K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, Hatfield, Herts AL9 7TA, UK
    Br J Sports Med 39:582-4. 2005
  6. ncbi Increased cartilage oligomeric matrix protein concentrations in equine digital flexor tendon sheath synovial fluid predicts intrathecal tendon damage
    Matthew R W Smith
    Royal Veterinary College, Equine Referral Hospital, North Mymms, UK
    Vet Surg 40:54-8. 2011
  7. ncbi Isolation and implantation of autologous equine mesenchymal stem cells from bone marrow into the superficial digital flexor tendon as a potential novel treatment
    R K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, University College, London, UK
    Equine Vet J 35:99-102. 2003
  8. ncbi In vitro evaluation of nonrigid support systems for the equine metacarpophalangeal joint
    R K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, UK
    Equine Vet J 34:726-31. 2002
  9. ncbi Tenocyte response to cyclical strain and transforming growth factor beta is dependent upon age and site of origin
    S A Goodman
    Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire, UK AL9 7TA
    Biorheology 41:613-28. 2004
  10. ncbi A molecular marker of type I collagen metabolism reflects changes in connective tissue remodelling associated with injury to the equine superficial digital flexor tendon
    B E Jackson
    Department of Veterinary Basic Sciences, The Royal Veterinary College, Royal College Street, London, NW1 OTU, UK
    Equine Vet J 35:211-3. 2003

Collaborators

Detail Information

Publications19

  1. ncbi The influence of ageing and exercise on tendon growth and degeneration--hypotheses for the initiation and prevention of strain-induced tendinopathies
    R K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK
    Comp Biochem Physiol A Mol Integr Physiol 133:1039-50. 2002
    ..Appropriate exercise regimes early in life may help to improve the quality of growing tendon, thereby reducing the incidence of injury during ageing or subsequent athletic career...
  2. ncbi The effect of early training and the adaptation and conditioning of skeletal tissues
    Roger K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Vet Clin North Am Equine Pract 24:37-51. 2008
    ..With appropriate monitoring owners, trainers, and veterinarians can apply the science underlying functional adaptation to the training of specific equine athletes, and so improve equine welfare...
  3. ncbi Gene expression markers of tendon fibroblasts in normal and diseased tissue compared to monolayer and three dimensional culture systems
    Sarah E Taylor
    Department of Veterinary Clinical Science, University of Liverpool, Neston, South Wirral, UK
    BMC Musculoskelet Disord 10:27. 2009
    ..This study aims to quantify gene expression markers that distinguish between tendon fibroblasts and other mesenchymal cells which may be used to investigate tenogenesis...
  4. ncbi Mesenchymal stem cell therapy for equine tendinopathy
    Roger K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, North Mymms, Hatfield, Hertfordshire, UK
    Disabil Rehabil 30:1752-8. 2008
    ..Autologous implantation of mesenchymal stem cells into tendon injuries may therefore improve clinical outcome although definitive proof of efficacy, which is still lacking, will require randomized controlled trials...
  5. ncbi Harnessing the stem cell for the treatment of tendon injuries: heralding a new dawn?
    R K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, Hatfield, Herts AL9 7TA, UK
    Br J Sports Med 39:582-4. 2005
  6. ncbi Increased cartilage oligomeric matrix protein concentrations in equine digital flexor tendon sheath synovial fluid predicts intrathecal tendon damage
    Matthew R W Smith
    Royal Veterinary College, Equine Referral Hospital, North Mymms, UK
    Vet Surg 40:54-8. 2011
    ..To evaluate digital flexor tendon sheath (DFTS) synovial fluid cartilage oligomeric matrix protein (COMP) concentrations as a molecular marker for intrathecal pathology...
  7. ncbi Isolation and implantation of autologous equine mesenchymal stem cells from bone marrow into the superficial digital flexor tendon as a potential novel treatment
    R K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, University College, London, UK
    Equine Vet J 35:99-102. 2003
  8. ncbi In vitro evaluation of nonrigid support systems for the equine metacarpophalangeal joint
    R K W Smith
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, UK
    Equine Vet J 34:726-31. 2002
    ..These data demonstrate that the contoured splint and the Dalmar tendon support boot (which is also easily fitted for use during exercise) are useful for the management of tendon/ligament injury and during rehabilitation...
  9. ncbi Tenocyte response to cyclical strain and transforming growth factor beta is dependent upon age and site of origin
    S A Goodman
    Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire, UK AL9 7TA
    Biorheology 41:613-28. 2004
    ..Our results suggest that tenocytes become differentiated at an early age and present tendon-specific responses...
  10. ncbi A molecular marker of type I collagen metabolism reflects changes in connective tissue remodelling associated with injury to the equine superficial digital flexor tendon
    B E Jackson
    Department of Veterinary Basic Sciences, The Royal Veterinary College, Royal College Street, London, NW1 OTU, UK
    Equine Vet J 35:211-3. 2003
  11. ncbi Two clinical manifestations of desmopathy of the accessory ligament of the deep digital flexor tendon in the hindlimb of 23 horses
    E Eliashar
    Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Equine Vet J 37:495-500. 2005
    ....
  12. ncbi Descriptive epidemiology of fracture, tendon and suspensory ligament injuries in National Hunt racehorses in training
    E R Ely
    Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Equine Vet J 41:372-8. 2009
    ..While fractures and tendon injuries are known to be important diseases in National Hunt (NH) racehorses during racing, there are no accurate estimates of their incidence in NH training yards...
  13. ncbi Ultrasonographic assessment of the superficial digital flexor tendons of National Hunt racehorses in training over two racing seasons
    C S Avella
    Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Equine Vet J 41:449-54. 2009
    ..It is important to ascertain the prevalence of superficial digital flexor tendon (SDFT) injuries and to improve methods of predicting injury in National Hunt (NH) racehorses...
  14. ncbi Evaluation of a filter-prepared platelet concentrate for the treatment of suspensory branch injuries in horses
    G Castelijns
    Equihealth Vetrinarios SL, Real Club de Polo de Barcelona, Barcelona, Spain
    Vet Comp Orthop Traumatol 24:363-9. 2011
    ..Platelet preparations have become a treatment for soft tissue injuries in horses. This study evaluated a novel filter-based system to concentrate platelets and assesses its value in the treatment of suspensory ligament branch desmitis...
  15. ncbi Osteoarthritis of the talocalcaneal joint in 18 horses
    R K W Smith
    Department of Veterinary Clinical Sciences, Royal Veterinary College, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Equine Vet J 37:166-71. 2005
    ..A novel surgical treatment is described which appears to offer significant improvement in the lameness. Further work is necessary to determine the causes of this condition and more effective management...
  16. ncbi Clinical update on the use of mesenchymal stem cells in equine orthopaedics
    D D Frisbie
    Colorado State University, Equine Orthopaedic Research Center, 300 West Drake Road, Fort Collins, Colorado 80523, USA and The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Equine Vet J 42:86-9. 2010
    ..This manuscript presents the genesis, issues and current state of stem cell treatment in equine medicine. Current literature supports the use of mesenchymal stem cells (MSCs) for treatment of orthopaedic problems...
  17. ncbi Treatment of chronic or recurrent proximal suspensory desmitis using radial pressure wave therapy in the horse
    O M Crowe
    Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Equine Vet J 36:313-6. 2004
    ..Further studies are required on the effect of RPWT employing histology and biomechanics in order to fully evaluate its use on equine tissues...
  18. ncbi Regenerative medicine for tendinous and ligamentous injuries of sport horses
    Lisa A Fortier
    Department of Clinical Sciences, VMC C3 181, Cornell University, Ithaca, NY 14853, USA
    Vet Clin North Am Equine Pract 24:191-201. 2008
    ..Successful restoration processes for any tissue are thought to recapitulate those of development, in which there are spatial and temporal interactions between scaffold, growth factors, and cell populations...
  19. ncbi Stem cell technology in equine tendon and ligament injuries
    Roger K W Smith
    Vet Rec 158:140. 2006