Eric Lim

Summary

Affiliation: Royal Brompton Hospital
Country: UK

Publications

  1. doi request reprint Therapeutic advances in non-small cell lung cancer
    Eric Vallieres
    Department of Thoracic Surgery, Swedish Cancer Institute, Seattle, WA, USA
    Thorax 67:1097-101. 2012
  2. doi request reprint Patients' perspective in the surgical decision-making process
    Eric Lim
    The Academic Division of Thoracic Surgery, The Royal Brompton Hospital, London, UK
    Thorac Surg Clin 22:539-43. 2012
  3. doi request reprint Proceedings of the IASLC International Workshop on Advances in Pulmonary Neuroendocrine Tumors 2007
    Eric Lim
    Imperial College and the Academic Division of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Oncol 3:1194-201. 2008
  4. doi request reprint The role of surgery in the treatment of limited disease small cell lung cancer: time to reevaluate
    Eric Lim
    Imperial College and Academic Division of Thoracic Surgery and Histopathology, Royal Brompton Hospital, London, UK
    J Thorac Oncol 3:1267-71. 2008
  5. ncbi request reprint Composite outcomes in cardiovascular research: a survey of randomized trials
    Eric Lim
    Papworth Hospital and Addenbrooke s Hospital, Cambridge, United Kingdom
    Ann Intern Med 149:612-7. 2008
  6. doi request reprint Preoperative versus postoperative chemotherapy in patients with resectable non-small cell lung cancer: systematic review and indirect comparison meta-analysis of randomized trials
    Eric Lim
    Imperial College and Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Oncol 4:1380-8. 2009
  7. doi request reprint Guidelines on the radical management of patients with lung cancer
    Eric Lim
    Academic Division of Thoracic Surgery, Royal Brompton Hospital, London, UK
    Thorax 65:iii1-27. 2010
  8. doi request reprint Non-small-cell lung cancer
    Peter Goldstraw
    Academic Department of Thoracic Surgery, Royal Brompton and Harefield NHS Foundation Trust, Imperial College School of Medicine, London, UK
    Lancet 378:1727-40. 2011
  9. ncbi request reprint Determinants of progression of coronary artery calcification in type 2 diabetes role of glycemic control and inflammatory/vascular calcification markers
    Dhakshinamurthy Vijay Anand
    Cardiac Imaging and Research Centre, Wellington Hospital, London, United Kingdom
    J Am Coll Cardiol 50:2218-25. 2007
  10. pmc Biological efficacy of low versus medium dose aspirin after coronary surgery: results from a randomized trial [NCT00262275]
    Eric Lim
    Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, CB3 8RE, UK
    BMC Med 4:12. 2006

Detail Information

Publications50

  1. doi request reprint Therapeutic advances in non-small cell lung cancer
    Eric Vallieres
    Department of Thoracic Surgery, Swedish Cancer Institute, Seattle, WA, USA
    Thorax 67:1097-101. 2012
    ..The contributors to this review are a distinguished international panel of experts who highlight recent advances in each of the major disciplines...
  2. doi request reprint Patients' perspective in the surgical decision-making process
    Eric Lim
    The Academic Division of Thoracic Surgery, The Royal Brompton Hospital, London, UK
    Thorac Surg Clin 22:539-43. 2012
    ....
  3. doi request reprint Proceedings of the IASLC International Workshop on Advances in Pulmonary Neuroendocrine Tumors 2007
    Eric Lim
    Imperial College and the Academic Division of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Oncol 3:1194-201. 2008
    ....
  4. doi request reprint The role of surgery in the treatment of limited disease small cell lung cancer: time to reevaluate
    Eric Lim
    Imperial College and Academic Division of Thoracic Surgery and Histopathology, Royal Brompton Hospital, London, UK
    J Thorac Oncol 3:1267-71. 2008
    ..Controversy remains as to when surgery should be considered. We sought to determine the survival after complete resection of SCLC and the prognostic impact of clinical and pathologic stage...
  5. ncbi request reprint Composite outcomes in cardiovascular research: a survey of randomized trials
    Eric Lim
    Papworth Hospital and Addenbrooke s Hospital, Cambridge, United Kingdom
    Ann Intern Med 149:612-7. 2008
    ..Composite end points are common in clinical trials...
  6. doi request reprint Preoperative versus postoperative chemotherapy in patients with resectable non-small cell lung cancer: systematic review and indirect comparison meta-analysis of randomized trials
    Eric Lim
    Imperial College and Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Oncol 4:1380-8. 2009
    ....
  7. doi request reprint Guidelines on the radical management of patients with lung cancer
    Eric Lim
    Academic Division of Thoracic Surgery, Royal Brompton Hospital, London, UK
    Thorax 65:iii1-27. 2010
    ....
  8. doi request reprint Non-small-cell lung cancer
    Peter Goldstraw
    Academic Department of Thoracic Surgery, Royal Brompton and Harefield NHS Foundation Trust, Imperial College School of Medicine, London, UK
    Lancet 378:1727-40. 2011
    ....
  9. ncbi request reprint Determinants of progression of coronary artery calcification in type 2 diabetes role of glycemic control and inflammatory/vascular calcification markers
    Dhakshinamurthy Vijay Anand
    Cardiac Imaging and Research Centre, Wellington Hospital, London, United Kingdom
    J Am Coll Cardiol 50:2218-25. 2007
    ....
  10. pmc Biological efficacy of low versus medium dose aspirin after coronary surgery: results from a randomized trial [NCT00262275]
    Eric Lim
    Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, CB3 8RE, UK
    BMC Med 4:12. 2006
    ..We conducted a double-blind randomised trial to establish the efficacy of low dose aspirin and to compare it against medium dose aspirin...
  11. ncbi request reprint Comparison of survival by allocation to medical therapy, surgery, or heart transplantation for ischemic advanced heart failure
    Eric Lim
    Transplant Unit, Papworth Hospital, Cambridge, UK
    J Heart Lung Transplant 24:983-9. 2005
    ..To ascertain survival of ischemic advanced heart failure patients by treatment allocation, we examined the outcome of transplant assessment patients allocated to medical therapy, high-risk conventional surgery, or transplantation...
  12. doi request reprint Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer
    Khaled M Sarraf
    Academic Division of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 137:425-8. 2009
    ..We sought to determine factors associated with increasing neutrophil/lymphocyte ratios and the stage-adjusted prognostic effect in patients undergoing resection for non-small cell lung cancer...
  13. doi request reprint A prospective, randomized trial comparing BioGlue and Vivostat for the control of alveolar air leak
    Elizabeth Belcher
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 140:32-8. 2010
    ..Vivostat (Vivostat A/S, Alleroed, Denmark) is an autologous fibrin sealant that confers certain advantages. It shows superior elastic properties, a faster absorption time, and the absence of risk of transmission of blood-borne diseases...
  14. pmc Predicting risk of intensive care unit admission after resection for non-small cell lung cancer: a validation study
    Lawrence Okiror
    Academic Division of Thoracic Surgery, Royal Brompton Hospital, London, UK
    Interact Cardiovasc Thorac Surg 14:31-3. 2012
    ..The area under the ROC curve was 0.66 (95% CI 0.53-0.79). The Brunelli scoring system had moderate discriminating ability to predict the risk of ICU admission after lung resection in our institution...
  15. doi request reprint The frequency of neuroendocrine cell hyperplasia in patients with pulmonary neuroendocrine tumours and non-neuroendocrine cell carcinomas
    Selim M H Rizvi
    Department of Histopathology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Histopathology 55:332-7. 2009
    ..To evaluate the frequency of neuroendocrine cell hyperplasia (NEH) in resected neuroendocrine tumours and non-neuroendocrine cell carcinomas and to study its relationship to selected clinical parameters...
  16. ncbi request reprint The impact of stage and cell type on the prognosis of pulmonary neuroendocrine tumors
    Eric Lim
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 130:969-72. 2005
    ..To clarify this relationship, we studied patients treated at our institution over a 23-year period...
  17. doi request reprint Prognostic significance of predominant histologic pattern and nuclear grade in resected adenocarcinoma of the lung: potential parameters for a grading system
    Jan H von der Thüsen
    Department of Histopathology, Royal Brompton and Harefield NHS Foundation Trust, London, UK
    J Thorac Oncol 8:37-44. 2013
    ..With a recently updated consensus classification, the aim of this study was to assess potential prognostic factors identifiable on routine histology, which might be used as grading parameters...
  18. doi request reprint Longitudinal study of the profile and predictors of left ventricular mass regression after stentless aortic valve replacement
    Eric Lim
    Department of Cardiac Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 85:2026-9. 2008
    ..The aim of this study was to evaluate the long-term profile and determine the factors that would influence the effect and rate of ventricular mass regression with time after aortic valve replacement with a stentless or a homograft valve...
  19. ncbi request reprint Dose-related efficacy of aspirin after coronary surgery in patients With Pl(A2) polymorphism (NCT00262275)
    Eric Lim
    Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, United Kingdom
    Ann Thorac Surg 83:134-8. 2007
    ....
  20. ncbi request reprint The relationship between plasma osteoprotegerin levels and coronary artery calcification in uncomplicated type 2 diabetic subjects
    Dhakshinamurthy Vijay Anand
    Cardiac Imaging and Research Centre, Wellington Hospital, St John s Wood, London, United Kingdom
    J Am Coll Cardiol 47:1850-7. 2006
    ....
  21. ncbi request reprint Intraoperative pleural lavage cytology is an independent prognostic indicator for staging non-small cell lung cancer
    Eric Lim
    Department of Thoracic Surgery, Royal Brompton Hospital, London, UK
    J Thorac Cardiovasc Surg 127:1113-8. 2004
    ..To ascertain the frequency and quantify the effect of this finding on survival, we performed a prospective study of intraoperative pleural lavage cytology...
  22. doi request reprint Debridement alone without decortication can achieve lung re-expansion in patients with empyema: an observational study
    Phoebe Kho
    Academic Division of Thoracic Surgery, The Royal Brompton Hospital, Imperial College, Sydney Street, London SW3 6NP, UK
    Interact Cardiovasc Thorac Surg 12:724-7. 2011
    ..937). Similar follow-up results were achieved by debridement alone without decortication in patients presenting with empyema, despite the presence of an underlying trapped lung...
  23. ncbi request reprint A prospective, randomized, controlled trial of the effectiveness of BioGlue in treating alveolar air leaks
    Patrick Tansley
    Department of Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London, United Kingdom
    J Thorac Cardiovasc Surg 132:105-12. 2006
    ..The aim of this study was to determine the effectiveness of BioGlue (CryoLife Europa Ltd, Hampshire, United Kingdom) in eliminating post-thoracotomy alveolar air leaks...
  24. ncbi request reprint Normal value of carotid intima-media thickness--a surrogate marker of atherosclerosis: quantitative assessment by B-mode carotid ultrasound
    Tiong K Lim
    Northwick Park Hospital and Institute of Post Graduate Medicine and Research, London, United Kingdom
    J Am Soc Echocardiogr 21:112-6. 2008
    ..The study is aimed to define the upper limit of carotid IMT at the common carotid artery (CCA) and its bifurcation among a healthy population in the United Kingdom...
  25. doi request reprint Breathlessness after pneumonectomy: consider postpneumonectomy syndrome
    Anthony J Bastin
    Unit of Critical Care, Royal Brompton Hospital, London, UK
    Clin Lung Cancer 11:423-5. 2010
    ..Clinicians caring for patients after pneumonectomy should be aware of this rare but treatable complication...
  26. doi request reprint Underestimation of duration of ventricular activation by 12-lead ECG compared with direct measurement of activation duration derived from implanted pacemaker leads
    Alison M Duncan
    Department of Echocardiography, Royal Brompton Hospital, London, United Kingdom
    Int J Cardiol 152:35-42. 2011
    ..To determine extent to which 12-lead ECG QRS duration (QRSd) reflects ventricular activation duration compared with time relations from unpaced ventricular myograms in cardiac resynchronisation therapy (CRT) patients...
  27. pmc Impact of collection and storage of lung tumor tissue on whole genome expression profiling
    Maxim B Freidin
    National Heart and Lung Institute, Imperial College London, London, United Kingdom
    J Mol Diagn 14:140-8. 2012
    ..Examination of FFPE specimens showed minimal correlation with fresh samples. This study shows that tissue collection immediately after lung resection with conservation in RNAlater is an optimal strategy for gene expression profiling...
  28. doi request reprint Surgical access rather than method of pleurodesis (pleurectomy or pleural abrasion) influences recurrence rates for pneumothorax surgery: systematic review and meta-analysis
    Andrea Billè
    Thoracic Surgery Department, Guy s and St Thomas Hospital, London SE1 9RT, UK
    Gen Thorac Cardiovasc Surg 60:321-5. 2012
    ..We aimed to evaluate the influence of the type of pleurodesis on recurrence whilst adjusting for surgical access by systematic review and meta-regression of randomised and non-randomised trials...
  29. doi request reprint Lung cancer: progress in diagnosis, staging and therapy
    Stephen G Spiro
    Royal Brompton Hospital, London SW3 6NP, UK
    Respirology 15:44-50. 2010
    ..Finally, targeted therapy for advanced non-small-cell lung cancer is highlighted as a development with early promise, but still much clarification is required, before it can be considered as a universal approach in late disease...
  30. ncbi request reprint Biological efficacy of low against medium dose aspirin regimen after coronary surgery: analysis of platelet function
    Jacqueline Cornelissen
    Department of Clinical Pharmacology, Papworth Hospital NHS Trust, Cambridge, CB3 8RE, UK
    Thromb Haemost 95:476-82. 2006
    ..In summary, there was no evidence for inherent or acquired aspirin-resistance in this surgical population, or for the involvement of either COX-2 or p38-MAPK...
  31. ncbi request reprint Remote ischemic preconditioning reduces myocardial and renal injury after elective abdominal aortic aneurysm repair: a randomized controlled trial
    Ziad A Ali
    Cambridge Cardiovascular Unit, Cambridge University Hospitals NHS Trust, Long Road, Cambridge, CB2 2QQ, UK
    Circulation 116:I98-105. 2007
    ..CONCLUSIONS: In patients undergoing elective open abdominal aortic aneurysm repair, RIPC reduces the incidence of postoperative myocardial injury, myocardial infarction, and renal impairment...
  32. pmc Innate immune responses to bacterial ligands in the peripheral human lung--role of alveolar epithelial TLR expression and signalling
    Andrew J Thorley
    Lung Cell Biology, Section of Pharmacology and Toxicology, National Heart and Lung Institute, Imperial College, London, United Kingdom
    PLoS ONE 6:e21827. 2011
    ....
  33. doi request reprint Clinical application of direct bronchial ultrasound to visualize and determine endobronchial tumor margins for surgical resection
    Khaled M Sarraf
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 86:1339-41. 2008
    ..We describe the first experience of direct bronchial (epi-bronchial) ultrasound to visualize and determine the endobronchial tumor margins for surgical resection...
  34. ncbi request reprint Regional ventricular dynamics during acute coronary occlusion: a comparison of invasive with non-invasive echocardiographic markers to detect and quantify myocardial ischaemia-observations made during off-pump coronary surgery
    Gerald S Carr-White
    Cardiac Department and Academic Department of Cardiac Surgery, Royal Brompton Hospital, Sydney Street, London SW3 6NP, United Kingdom
    Int J Cardiol 113:376-84. 2006
    ..We therefore sought to compare these non-invasive markers during acute coronary occlusion in humans...
  35. pmc A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses
    Timothy Gatheral
    Cardiothoracic Pharmacology, National Heart and Lung Institute, Imperial College, London, United Kingdom
    PLoS ONE 7:e42386. 2012
    ..This data supports the potential utility of NOD1 and RIP2 as therapeutic targets in human disease where vascular inflammation is a clinical feature, such as in sepsis and septic shock...
  36. ncbi request reprint A versatile technique for aortic root replacement without pre-manufactured composite graft: a 12-year experience
    James C Halstead
    Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, UK
    J Heart Valve Dis 13:717-21. 2004
    ..Separate graft and prosthetic valve components were used to allow freedom of valve choice and the use of an appropriately sized graft for the distal aortic anastomosis...
  37. ncbi request reprint A systematic review of randomized trials comparing revascularization rate and graft patency of off-pump and conventional coronary surgery
    Eric Lim
    Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, United Kingdom
    J Thorac Cardiovasc Surg 132:1409-13. 2006
    ..We sought to evaluate the impact of off-pump surgery on completeness of revascularization and graft patency compared with conventional surgery...
  38. ncbi request reprint Recurrence rates of video-assisted thoracoscopic versus open surgery in the prevention of recurrent pneumothoraces: a systematic review of randomised and non-randomised trials
    Allanah Barker
    Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, UK
    Lancet 370:329-35. 2007
    ..Our aim was to do a systematic review of randomised and non-randomised studies to compare recurrence rates between the two forms of surgical access...
  39. ncbi request reprint Allogenic blood transfusion does not predispose to infection after cardiac surgery
    Ziad A Ali
    Department of Cardiothoracic Surgery, Papworth Hospital, Papworth Everard, Cambridge, United Kingdom
    Ann Thorac Surg 78:1542-6. 2004
    ..Many retrospective studies report increased postoperative infection after allogenic blood transfusion. To investigate this phenomenon, we prospectively studied 232 patients undergoing cardiac surgery...
  40. ncbi request reprint A validated simple model to predict coexistent coronary disease in patients undergoing mitral valve surgery
    Eric Lim
    Department of Cardiothoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 129:1318-21. 2005
    ..We recommend screening angiography at 3 or more points. This model was previously derived from 359 patients at Papworth Hospital...
  41. ncbi request reprint Effect of dobutamine stress on left ventricular filling in ischemic dilated cardiomyopathy: pathophysiology and prognostic implications
    Alison M Duncan
    Department of Echocardiography, Royal Brompton Hospital, London, United Kingdom
    J Am Coll Cardiol 46:488-96. 2005
    ..The purpose of this research was to study the effect of dobutamine on left ventricular (LV) filling in ischemic cardiomyopathy (ICM) and to determine whether restrictive filling pattern (RFP) at peak stress has prognostic value...
  42. ncbi request reprint Comparison of segmental and global markers of dyssynchrony in predicting clinical response to cardiac resynchronization
    Alison M Duncan
    Department of Echocardiography, Royal Brompton Hospital and, Imperial College, Sydney Street, London SW3 6NP, UK
    Eur Heart J 27:2426-32. 2006
    ..We compared the extent to which the values of ventricular dyssynchrony and t-IVT predict clinical benefits of CRT...
  43. ncbi request reprint A surgeon's case volume of oesophagectomy for cancer strongly influences the operative mortality rate
    Marcello Migliore
    General Thoracic Surgery, Papworth Hospital, University of Cambridge Teaching Hospital, Cambridge, UK
    Eur J Cardiothorac Surg 32:375-80. 2007
    ..To assess if individual case volume of oesophagectomy for cancer influences the risk of mortality and long-term survival...
  44. ncbi request reprint Prevalence of silent myocardial ischemia in asymptomatic individuals with subclinical atherosclerosis detected by electron beam tomography
    D Vijay Anand
    Cardiac Imaging and Research Centre, The Wellington Hospital, London, United Kingdom
    J Nucl Cardiol 11:450-7. 2004
    ..Hence, we prospectively evaluated the prevalence of myocardial ischemia in asymptomatic patients with cardiovascular risk factors and subclinical atherosclerosis...
  45. ncbi request reprint A simple model to predict coronary disease in patients undergoing operation for mitral regurgitation
    Eric Lim
    Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, United Kingdom
    Ann Thorac Surg 75:1820-5. 2003
    ..This study aims to evaluate candidate selection strategy using risk factor identification and logistic regression and to develop an additive model for the prediction of coexistent coronary disease...
  46. ncbi request reprint Surgery for left ventricular free wall rupture: patch glue repair without extracorporeal circulation
    Sergio J Canovas
    Department of Cardiac Surgery, University General Hospital, Valencia, Spain
    Eur J Cardiothorac Surg 23:639-41. 2003
    ..We performed this technique on 17 patients from 1993 to 2001, with a operative (30-day) mortality of 23.5% with a post-discharge survival of 85% at 2.2 years...
  47. ncbi request reprint Midterm clinical and echocardiographic results with patch glue repair of left ventricular free wall rupture
    Sergio J Canovas
    Department of Cardiac Surgery, University General Hospital, Valencia, Spain
    Circulation 108:II237-40. 2003
    ..Left ventricular free wall rupture (LVFWR) is a dramatic complication after myocardial infarction. We present our mid-term clinical and echocardiographic results of LVFWR with an epicardial patch without cardiopulmonary bypass...
  48. ncbi request reprint Value of intraoperative pleural lavage in staging non-small cell lung cancer
    Peter Goldstraw
    J Thorac Cardiovasc Surg 128:331. 2004
  49. ncbi request reprint Surgical sealants for air leaks after pulmonary surgery
    Eric Lim
    Eur J Cardiothorac Surg 32:552-3. 2007
  50. ncbi request reprint Invited commentary
    Eric Lim
    Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, CB3 8RE United Kingdom
    Ann Thorac Surg 83:202-3. 2007