Christine A Lee

Summary

Affiliation: Royal Brompton Hospital
Country: UK

Publications

  1. ncbi request reprint The evidence behind inhibitor treatment with porcine factor VIII
    Christine A Lee
    The Haemophilia Centre and Haemostasis Unit, Royal Free Hospital NHS Trust, London, UK
    Pathophysiol Haemost Thromb 32:5-8. 2002
  2. ncbi request reprint The natural history and antiviral treatment of hepatitis C in haemophilia
    C Lee
    The Haemophilia Centre and Haemostasis Unit, The Royal Free Hospital, London, UK
    Haemophilia 8:322-9. 2002
  3. doi request reprint Inherited bleeding disorders in older women
    Rezan A Kadir
    The Royal Free Hospital, London, UK
    Maturitas 72:35-41. 2012
  4. doi request reprint The obstetric experience of women with factor XI deficiency
    Claudia Chi
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    Acta Obstet Gynecol Scand 88:1095-100. 2009
  5. ncbi request reprint Transfusion-transmitted infection in hemophilia in developing countries
    Thynn Thynn Yee
    Haemophilia Centre and Haemostasis Unit, The Royal Free Hospital, London, United Kingdom
    Semin Thromb Hemost 31:527-37. 2005
  6. ncbi request reprint Markers of HIV-1 disease progression in individuals with haemophilia coinfected with hepatitis C virus: a longitudinal study
    Caroline A Sabin
    Department of Primary Care and Population Sciences, Royal Free Centre for HIV Medicine, Royal Free and University College Medical School, London, UK
    Lancet 360:1546-51. 2002
  7. ncbi request reprint von Willebrand factor: the new treatment paradigm--introduction
    Christine A Lee
    Haemophilia Centre and Haemostasis Unit, Royal Free Hospital, London, UK
    Blood Coagul Fibrinolysis 16:S1-2. 2005
  8. ncbi request reprint Molecular challenges and viral diseases
    Simon A Brown
    Katharine Dormandy Haemophilia Centre and Haemostasis Unit, Royal Free Hospital, London, UK
    Haemophilia 9:727-37. 2003
  9. doi request reprint Puerperal loss (lochia) in women with or without inherited bleeding disorders
    Claudia Chi
    Department of Obstetrics and Gynaecology, and Katharine Dormandy Haemophilia Centre and Thrombosis Unit, Royal Free Hospital, Pond Street, London, UK
    Am J Obstet Gynecol 203:56.e1-5. 2010
  10. ncbi request reprint von Willebrand disease in women with menorrhagia: a systematic review
    Meena Shankar
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    BJOG 111:734-40. 2004

Collaborators

Detail Information

Publications24

  1. ncbi request reprint The evidence behind inhibitor treatment with porcine factor VIII
    Christine A Lee
    The Haemophilia Centre and Haemostasis Unit, Royal Free Hospital NHS Trust, London, UK
    Pathophysiol Haemost Thromb 32:5-8. 2002
    ..Efforts to secure source plasma free of viral markers, particularly porcine parvovirus, have limited the supply of this therapeutic product...
  2. ncbi request reprint The natural history and antiviral treatment of hepatitis C in haemophilia
    C Lee
    The Haemophilia Centre and Haemostasis Unit, The Royal Free Hospital, London, UK
    Haemophilia 8:322-9. 2002
    ..Liver transplantation is indicated for patients with haemophilia who have decompensated hepatitis C infection...
  3. doi request reprint Inherited bleeding disorders in older women
    Rezan A Kadir
    The Royal Free Hospital, London, UK
    Maturitas 72:35-41. 2012
    ..Awareness of IBDs among health care providers, early diagnosis and appropriate management in a multidisciplinary approach is required to minimise the bleeding complications for women with IBDs...
  4. doi request reprint The obstetric experience of women with factor XI deficiency
    Claudia Chi
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    Acta Obstet Gynecol Scand 88:1095-100. 2009
    ..The unpredictable nature of their bleeding tendency demands careful planning and close collaborations between obstetricians and hematologists...
  5. ncbi request reprint Transfusion-transmitted infection in hemophilia in developing countries
    Thynn Thynn Yee
    Haemophilia Centre and Haemostasis Unit, The Royal Free Hospital, London, United Kingdom
    Semin Thromb Hemost 31:527-37. 2005
    ..However, there are still several challenges in delivering antiretroviral treatment that must be addressed before the full impact of these transmitted infections is known...
  6. ncbi request reprint Markers of HIV-1 disease progression in individuals with haemophilia coinfected with hepatitis C virus: a longitudinal study
    Caroline A Sabin
    Department of Primary Care and Population Sciences, Royal Free Centre for HIV Medicine, Royal Free and University College Medical School, London, UK
    Lancet 360:1546-51. 2002
    ..We aimed to assess the relation between markers of liver function and progression to AIDS and death in individuals with haemophilia infected with HIV-1 and hepatitis C virus...
  7. ncbi request reprint von Willebrand factor: the new treatment paradigm--introduction
    Christine A Lee
    Haemophilia Centre and Haemostasis Unit, Royal Free Hospital, London, UK
    Blood Coagul Fibrinolysis 16:S1-2. 2005
  8. ncbi request reprint Molecular challenges and viral diseases
    Simon A Brown
    Katharine Dormandy Haemophilia Centre and Haemostasis Unit, Royal Free Hospital, London, UK
    Haemophilia 9:727-37. 2003
  9. doi request reprint Puerperal loss (lochia) in women with or without inherited bleeding disorders
    Claudia Chi
    Department of Obstetrics and Gynaecology, and Katharine Dormandy Haemophilia Centre and Thrombosis Unit, Royal Free Hospital, Pond Street, London, UK
    Am J Obstet Gynecol 203:56.e1-5. 2010
    ..To assess the quantity and duration of lochia in women with or without inherited bleeding disorders and to identify factors that influence lochial loss...
  10. ncbi request reprint von Willebrand disease in women with menorrhagia: a systematic review
    Meena Shankar
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    BJOG 111:734-40. 2004
    ..To determine the prevalence of von Willebrand disease in women presenting with menorrhagia...
  11. ncbi request reprint NKT cell subsets in infection and inflammation
    Woon Ling Chan
    Department of Biochemical Pharmacology, Queen Mary s School of Medicine, University of London, London, UK
    Immunol Lett 85:159-63. 2003
    ..Our data therefore demonstrate that ST2L and IL-18R could serve as important determinants of the immune status of human diseases...
  12. ncbi request reprint Single-dose pharmacokinetics of porcine factor VIII (Hyate C)
    Cedric Hermans
    Thromb Haemost 87:352-3. 2002
  13. ncbi request reprint Periarticular aneurysm following total knee replacement in hemophilic arthropathy. A case report
    Haroon A Mann
    Haemophilia Centre and Haemostasis Unit, Royal Free and University College School of Medicine Royal Free Campus, Pond Street, Hampstead, London NW3 2QG, United Kingdom
    J Bone Joint Surg Am 85:2437-40. 2003
  14. ncbi request reprint The prognostic value of a single hepatitis C virus RNA load measurement taken early after human immunodeficiency virus seroconversion
    Esteban Herrero-Martinez
    Department of Virology, Royal Free and University College Medical School, Royal Free Hospital, London, United Kingdom
    J Infect Dis 186:470-6. 2002
    ..25; P=.01). Adjusting for HIV RNA levels, CD4 cell counts, and the age effect, HCV RNA load >5.90 log(10) copies/mL was predictive of progression to AIDS and all-cause mortality over a period of at least 15 years...
  15. ncbi request reprint Haemostasis: from bench to bedside
    Simon A Brown
    Haemophilia 8:685-93. 2002
  16. ncbi request reprint Mortality rates, life expectancy, and causes of death in people with hemophilia A or B in the United Kingdom who were not infected with HIV
    Sarah C Darby
    Clinical Trial Service Unit, University of Oxford, Oxford, UK
    Blood 110:815-25. 2007
    ..There was no evidence of any death from variant Creutzfeldt-Jakob disease or from conditions that could be confused with it...
  17. ncbi request reprint Inhibitor development in hemophiliacs: the roles of genetic versus environmental factors
    Christine A Lee
    Haemophilia Centre and Haemostasis Unit, Royal Free and University College Medical School, UCL, London, United Kingdom
    Semin Thromb Hemost 32:10-4. 2006
    ..There is much interest in identifying such genetic and treatment-related factors to help minimize the risk of inhibitor development and improve treatment outcomes...
  18. ncbi request reprint Cost-utility analysis of primary prophylaxis versus treatment on-demand for individuals with severe haemophilia
    Alexander H Miners
    Health Economics Research Group, Brunel University, Uxbridge, United Kingdom
    Pharmacoeconomics 20:759-74. 2002
    ..To assess the cost effectiveness of primary prophylaxis with clotting factor instead of treatment following a bleed (on-demand) for individuals with severe haemophilia...
  19. pmc Twenty five years of HIV infection in haemophilic men in Britain: an observational study
    Caroline A Sabin
    Department of Primary Care and Population Sciences, Royal Free and UC Medical School, London NW3 2PF
    BMJ 331:997-8. 2005
  20. ncbi request reprint Long-term patterns of hepatitis C virus RNA concentrations in a cohort of HIV seronegative men with bleeding disorders
    Caroline A Sabin
    Haemophilia Centre and Haemostasis Unit and Department of Primary Care and Population Sciences, Royal Free and University Medical School, London, United Kingdom
    J Med Virol 68:68-75. 2002
    ....
  21. ncbi request reprint The incidence of lymphoma in the UK haemophilia population between 1978 and 1999
    Jonathan T Wilde
    Department of Haematology, University Hospital Birmingham NHS Trust, Edgbaston, Birmingham B15 2TH, UK
    AIDS 16:1803-7. 2002
    ..To determine the incidence of non-Hodgkin's lymphoma (NHL) and Hodgkin's disease (HD) in the UK haemophilia population during the 22 year period 1978-1999...
  22. ncbi request reprint The impact of HIV on mortality rates in the complete UK haemophilia population
    Sarah C Darby
    AIDS 18:525-33. 2004
    ..To estimate the effect of HIV-1 infection on subsequent mortality in a complete population...
  23. ncbi request reprint Prevalence, causes, and characterization of factor XI inhibitors in patients with inherited factor XI deficiency
    Ophira Salomon
    Thrombosis and Hemostasis Research Institute, Tissue Typing Laboratory, Sheba Medical Center, Tel Hashomer, Israel
    Blood 101:4783-8. 2003
    ..The results imply that patients with a very low factor XI level are susceptible to development of an inhibitor following plasma replacement...
  24. ncbi request reprint The effect of highly active antiretroviral therapy for HIV on the anti-HCV specific humoral immune response
    Esteban Herrero-Martinez
    Department of Virology, Royal Free and University College Medical School, London, United Kingdom
    J Med Virol 72:187-93. 2004
    ..The relationship disappeared or was obscured after therapy (R = 0.24, P = 0.30 and R = 0.16, P = 0.50, respectively). Thus, we show that HAART affects the HCV specific humoral immune responses without affecting the HCV RNA level...