Charlotte Lawson

Summary

Affiliation: Royal Veterinary College
Country: UK

Publications

  1. ncbi Influence of chylomicron remnants on human monocyte activation in vitro
    C Bentley
    Cardiovascular Biology and Inflammation Research Group, Veterinary Basic Sciences, Royal Veterinary College, Royal College Street, London NW1 0TU, UK
    Nutr Metab Cardiovasc Dis 21:871-8. 2011
  2. ncbi Anti-intercellular adhesion molecule-1 antibodies in sera of heart transplant recipients: a role in endothelial cell activation
    Charlotte Lawson
    Transplant Immunology Group, Imperial College, Heart Science Centre, Harefield Hospital, Harefield, Middlesex, United Kingdom
    Transplantation 80:264-71. 2005
  3. ncbi ICAM-1 signaling in endothelial cells
    Charlotte Lawson
    Veterinary Basic Sciences, Royal Veterinary College, London, UK
    Pharmacol Rep 61:22-32. 2009
  4. ncbi Expression of endothelial intercellular adhesion molecule-1 is determined by genotype: effects on efficiency of leukocyte adhesion to human endothelial cells
    Angela L Holder
    Transplant Immunology Group Imperial College London, Heart Science Centre, Harefield Hospital, Harefield, Middlesex UB9 6JH, United Kingdom
    Hum Immunol 69:71-8. 2008
  5. ncbi Microparticle formation after co-culture of human whole blood and umbilical artery in a novel in vitro model of flow
    Emma Holtom
    Department of Veterinary Basic Sciences, Royal Veterinary College, London, United Kingdom
    Cytometry A 81:390-9. 2012
  6. ncbi Leucocyte adhesion under haemodynamic flow conditions
    Charlotte Lawson
    Veterinary Basic Sciences, Royal Veterinary College, London, UK
    Methods Mol Biol 616:31-47. 2010
  7. ncbi Microparticle formation after exposure of blood to activated endothelium under flow
    Marion G Macey
    Department of Haematology, The Royal London Hospital, London, UK
    Cytometry A 77:761-8. 2010
  8. ncbi Inhibition of macrophage inflammatory cytokine secretion by chylomicron remnants is dependent on their uptake by the low density lipoprotein receptor
    Valerie S Graham
    Department of Veterinary Basic Sciences, The Royal Veterinary College, London, UK
    Biochim Biophys Acta 1811:209-20. 2011
  9. ncbi Expression of human ecto-5'-nucleotidase in pig endothelium increases adenosine production and protects from NK cell-mediated lysis
    Foy N Osborne
    Heart Science Centre, Imperial College at Harefield Hospital, Harefield, Middlesex, UK
    Am J Transplant 5:1248-55. 2005
  10. ncbi IFN-gamma reverses the stop signal allowing migration of antigen-specific T cells into inflammatory sites
    Szun S Tay
    National Heart and Lung Institute, Imperial College School of Medicine, Harefield Hospital, Harefield, Middlesex, United Kingdom
    J Immunol 170:3315-22. 2003

Collaborators

Detail Information

Publications10

  1. ncbi Influence of chylomicron remnants on human monocyte activation in vitro
    C Bentley
    Cardiovascular Biology and Inflammation Research Group, Veterinary Basic Sciences, Royal Veterinary College, Royal College Street, London NW1 0TU, UK
    Nutr Metab Cardiovasc Dis 21:871-8. 2011
    ..Here, the contribution of CMR to activation of monocyte pro-inflammatory pathways was assessed using an in vitro model...
  2. ncbi Anti-intercellular adhesion molecule-1 antibodies in sera of heart transplant recipients: a role in endothelial cell activation
    Charlotte Lawson
    Transplant Immunology Group, Imperial College, Heart Science Centre, Harefield Hospital, Harefield, Middlesex, United Kingdom
    Transplantation 80:264-71. 2005
    ....
  3. ncbi ICAM-1 signaling in endothelial cells
    Charlotte Lawson
    Veterinary Basic Sciences, Royal Veterinary College, London, UK
    Pharmacol Rep 61:22-32. 2009
    ....
  4. ncbi Expression of endothelial intercellular adhesion molecule-1 is determined by genotype: effects on efficiency of leukocyte adhesion to human endothelial cells
    Angela L Holder
    Transplant Immunology Group Imperial College London, Heart Science Centre, Harefield Hospital, Harefield, Middlesex UB9 6JH, United Kingdom
    Hum Immunol 69:71-8. 2008
    ..This may explain the previously described associations of ICAM-1 polymorphisms with chronic inflammatory disease...
  5. ncbi Microparticle formation after co-culture of human whole blood and umbilical artery in a novel in vitro model of flow
    Emma Holtom
    Department of Veterinary Basic Sciences, Royal Veterinary College, London, United Kingdom
    Cytometry A 81:390-9. 2012
    ....
  6. ncbi Leucocyte adhesion under haemodynamic flow conditions
    Charlotte Lawson
    Veterinary Basic Sciences, Royal Veterinary College, London, UK
    Methods Mol Biol 616:31-47. 2010
    ....
  7. ncbi Microparticle formation after exposure of blood to activated endothelium under flow
    Marion G Macey
    Department of Haematology, The Royal London Hospital, London, UK
    Cytometry A 77:761-8. 2010
    ..These data strongly suggest that interactions of blood with inflamed EC can modulate production of CD62P and TF bearing MP under flow conditions, and thus may contribute to a prothrombotic environment...
  8. ncbi Inhibition of macrophage inflammatory cytokine secretion by chylomicron remnants is dependent on their uptake by the low density lipoprotein receptor
    Valerie S Graham
    Department of Veterinary Basic Sciences, The Royal Veterinary College, London, UK
    Biochim Biophys Acta 1811:209-20. 2011
    ..Thus, the receptor-mediated route of uptake of CMR plays a crucial role in modulating their effects on inflammatory processes in macrophages...
  9. ncbi Expression of human ecto-5'-nucleotidase in pig endothelium increases adenosine production and protects from NK cell-mediated lysis
    Foy N Osborne
    Heart Science Centre, Imperial College at Harefield Hospital, Harefield, Middlesex, UK
    Am J Transplant 5:1248-55. 2005
    ..We suggest that overexpression of E5'N in EC of transgenic pigs is a possible strategy to ameliorate rejection after xenotransplantation...
  10. ncbi IFN-gamma reverses the stop signal allowing migration of antigen-specific T cells into inflammatory sites
    Szun S Tay
    National Heart and Lung Institute, Imperial College School of Medicine, Harefield Hospital, Harefield, Middlesex, United Kingdom
    J Immunol 170:3315-22. 2003
    ..We conclude that cognate interaction between T cells and endothelial MHC class II initiates a stop signal possibly similar to an immunological synapse, but this is overcome in an inflammatory milieu...