Charlotte Lawson

Summary

Affiliation: Royal Veterinary College
Country: UK

Publications

  1. pmc Agonistic anti-ICAM-1 antibodies in scleroderma: activation of endothelial pro-inflammatory cascades
    Sabine I Wolf
    Department of Comparative Biomedical Sciences, The Royal Veterinary College, London, UK
    Vascul Pharmacol 59:19-26. 2013
  2. pmc The oxidative state of chylomicron remnants influences their modulation of human monocyte activation
    Sandra Armengol Lopez
    Department of Physiology, Faculty of Medicine and Dentistry, University of the Basque Country, Sarriena s n, 48940 Leioa, Spain
    Int J Vasc Med 2012:942512. 2012
  3. pmc Influence of chylomicron remnants on human monocyte activation in vitro
    C Bentley
    Cardiovascular Biology and Inflammation Research Group, Veterinary Basic Sciences, Royal Veterinary College, Royal College Street, London NW1 0TU, UK
    Nutr Metab Cardiovasc Dis 21:871-8. 2011
  4. ncbi request reprint Anti-intercellular adhesion molecule-1 antibodies in sera of heart transplant recipients: a role in endothelial cell activation
    Charlotte Lawson
    Transplant Immunology Group, Imperial College, Heart Science Centre, Harefield Hospital, Harefield, Middlesex, United Kingdom
    Transplantation 80:264-71. 2005
  5. ncbi request reprint ICAM-1 signaling in endothelial cells
    Charlotte Lawson
    Veterinary Basic Sciences, Royal Veterinary College, London, UK
    Pharmacol Rep 61:22-32. 2009
  6. doi request reprint Expression of endothelial intercellular adhesion molecule-1 is determined by genotype: effects on efficiency of leukocyte adhesion to human endothelial cells
    Angela L Holder
    Transplant Immunology Group Imperial College London, Heart Science Centre, Harefield Hospital, Harefield, Middlesex UB9 6JH, United Kingdom
    Hum Immunol 69:71-8. 2008
  7. doi request reprint Microparticle formation after co-culture of human whole blood and umbilical artery in a novel in vitro model of flow
    Emma Holtom
    Department of Veterinary Basic Sciences, Royal Veterinary College, London, United Kingdom
    Cytometry A 81:390-9. 2012
  8. ncbi request reprint Microparticle formation after exposure of blood to activated endothelium under flow
    Marion G Macey
    Department of Haematology, The Royal London Hospital, London, UK
    Cytometry A 77:761-8. 2010
  9. doi request reprint Leucocyte adhesion under haemodynamic flow conditions
    Charlotte Lawson
    Veterinary Basic Sciences, Royal Veterinary College, London, UK
    Methods Mol Biol 616:31-47. 2010
  10. pmc Live Brugia malayi microfilariae inhibit transendothelial migration of neutrophils and monocytes
    Jan Hendrik Schroeder
    Royal Veterinary College, University of London, London, United Kingdom
    PLoS Negl Trop Dis 6:e1914. 2012

Collaborators

Detail Information

Publications14

  1. pmc Agonistic anti-ICAM-1 antibodies in scleroderma: activation of endothelial pro-inflammatory cascades
    Sabine I Wolf
    Department of Comparative Biomedical Sciences, The Royal Veterinary College, London, UK
    Vascul Pharmacol 59:19-26. 2013
    ....
  2. pmc The oxidative state of chylomicron remnants influences their modulation of human monocyte activation
    Sandra Armengol Lopez
    Department of Physiology, Faculty of Medicine and Dentistry, University of the Basque Country, Sarriena s n, 48940 Leioa, Spain
    Int J Vasc Med 2012:942512. 2012
    ..These studies suggest that the oxidative state of CMRs modulates their stimulation of the activation of peripheral blood human monocytes and that dietary antioxidants may provide some protection against these atherogenic effects...
  3. pmc Influence of chylomicron remnants on human monocyte activation in vitro
    C Bentley
    Cardiovascular Biology and Inflammation Research Group, Veterinary Basic Sciences, Royal Veterinary College, Royal College Street, London NW1 0TU, UK
    Nutr Metab Cardiovasc Dis 21:871-8. 2011
    ..Here, the contribution of CMR to activation of monocyte pro-inflammatory pathways was assessed using an in vitro model...
  4. ncbi request reprint Anti-intercellular adhesion molecule-1 antibodies in sera of heart transplant recipients: a role in endothelial cell activation
    Charlotte Lawson
    Transplant Immunology Group, Imperial College, Heart Science Centre, Harefield Hospital, Harefield, Middlesex, United Kingdom
    Transplantation 80:264-71. 2005
    ....
  5. ncbi request reprint ICAM-1 signaling in endothelial cells
    Charlotte Lawson
    Veterinary Basic Sciences, Royal Veterinary College, London, UK
    Pharmacol Rep 61:22-32. 2009
    ....
  6. doi request reprint Expression of endothelial intercellular adhesion molecule-1 is determined by genotype: effects on efficiency of leukocyte adhesion to human endothelial cells
    Angela L Holder
    Transplant Immunology Group Imperial College London, Heart Science Centre, Harefield Hospital, Harefield, Middlesex UB9 6JH, United Kingdom
    Hum Immunol 69:71-8. 2008
    ..This may explain the previously described associations of ICAM-1 polymorphisms with chronic inflammatory disease...
  7. doi request reprint Microparticle formation after co-culture of human whole blood and umbilical artery in a novel in vitro model of flow
    Emma Holtom
    Department of Veterinary Basic Sciences, Royal Veterinary College, London, United Kingdom
    Cytometry A 81:390-9. 2012
    ....
  8. ncbi request reprint Microparticle formation after exposure of blood to activated endothelium under flow
    Marion G Macey
    Department of Haematology, The Royal London Hospital, London, UK
    Cytometry A 77:761-8. 2010
    ..These data strongly suggest that interactions of blood with inflamed EC can modulate production of CD62P and TF bearing MP under flow conditions, and thus may contribute to a prothrombotic environment...
  9. doi request reprint Leucocyte adhesion under haemodynamic flow conditions
    Charlotte Lawson
    Veterinary Basic Sciences, Royal Veterinary College, London, UK
    Methods Mol Biol 616:31-47. 2010
    ....
  10. pmc Live Brugia malayi microfilariae inhibit transendothelial migration of neutrophils and monocytes
    Jan Hendrik Schroeder
    Royal Veterinary College, University of London, London, United Kingdom
    PLoS Negl Trop Dis 6:e1914. 2012
    ..Overall, this work presents important insights into the immunological function of the vascular endothelium during an infection with B. malayi...
  11. doi request reprint Inhibition of macrophage inflammatory cytokine secretion by chylomicron remnants is dependent on their uptake by the low density lipoprotein receptor
    Valerie S Graham
    Department of Veterinary Basic Sciences, The Royal Veterinary College, London, UK
    Biochim Biophys Acta 1811:209-20. 2011
    ..Thus, the receptor-mediated route of uptake of CMR plays a crucial role in modulating their effects on inflammatory processes in macrophages...
  12. ncbi request reprint IFN-gamma reverses the stop signal allowing migration of antigen-specific T cells into inflammatory sites
    Szun S Tay
    National Heart and Lung Institute, Imperial College School of Medicine, Harefield Hospital, Harefield, Middlesex, United Kingdom
    J Immunol 170:3315-22. 2003
    ..We conclude that cognate interaction between T cells and endothelial MHC class II initiates a stop signal possibly similar to an immunological synapse, but this is overcome in an inflammatory milieu...
  13. ncbi request reprint Expression of human ecto-5'-nucleotidase in pig endothelium increases adenosine production and protects from NK cell-mediated lysis
    Foy N Osborne
    Heart Science Centre, Imperial College at Harefield Hospital, Harefield, Middlesex, UK
    Am J Transplant 5:1248-55. 2005
    ..We suggest that overexpression of E5'N in EC of transgenic pigs is a possible strategy to ameliorate rejection after xenotransplantation...
  14. ncbi request reprint Human peripheral blood monocytes express protease receptor-2 and respond to receptor activation by production of IL-6, IL-8, and IL-1{beta}
    Ulrika Johansson
    Department of Haematology, Barts and The London NHS Trust, London, E1 1BB, UK
    J Leukoc Biol 78:967-75. 2005
    ..The results presented thus suggest that PAR-2 contributes to inflammatory responses by inducing the production of proinflammatory cytokines in peripheral blood monocytes...