Peter Goldstraw

Summary

Affiliation: Royal Brompton Hospital
Country: UK

Publications

  1. doi request reprint New staging system: how does it affect our practice?
    Peter Goldstraw
    National Heart and Lung Institute, Imperial College, London, United Kingdom
    J Clin Oncol 31:984-91. 2013
  2. doi request reprint Updated staging system for lung cancer
    Peter Goldstraw
    Academic Department of Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Surg Oncol Clin N Am 20:655-66. 2011
  3. ncbi request reprint The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours
    Peter Goldstraw
    Royal Brompton Hospital, Imperial College, London, United Kingdom
    J Thorac Oncol 2:706-14. 2007
  4. ncbi request reprint A prospective, randomized, controlled trial of the effectiveness of BioGlue in treating alveolar air leaks
    Patrick Tansley
    Department of Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London, United Kingdom
    J Thorac Cardiovasc Surg 132:105-12. 2006
  5. doi request reprint Non-small-cell lung cancer
    Peter Goldstraw
    Academic Department of Thoracic Surgery, Royal Brompton and Harefield NHS Foundation Trust, Imperial College School of Medicine, London, UK
    Lancet 378:1727-40. 2011
  6. doi request reprint A prospective, randomized trial comparing BioGlue and Vivostat for the control of alveolar air leak
    Elizabeth Belcher
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 140:32-8. 2010
  7. doi request reprint The role of surgery in the treatment of limited disease small cell lung cancer: time to reevaluate
    Eric Lim
    Imperial College and Academic Division of Thoracic Surgery and Histopathology, Royal Brompton Hospital, London, UK
    J Thorac Oncol 3:1267-71. 2008
  8. doi request reprint The frequency of neuroendocrine cell hyperplasia in patients with pulmonary neuroendocrine tumours and non-neuroendocrine cell carcinomas
    Selim M H Rizvi
    Department of Histopathology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Histopathology 55:332-7. 2009
  9. pmc Assessment of cell line models of primary human cells by Raman spectral phenotyping
    Robin J Swain
    Department of Materials, Imperial College London, London, United Kingdom
    Biophys J 98:1703-11. 2010
  10. pmc Innate immune responses to bacterial ligands in the peripheral human lung--role of alveolar epithelial TLR expression and signalling
    Andrew J Thorley
    Lung Cell Biology, Section of Pharmacology and Toxicology, National Heart and Lung Institute, Imperial College, London, United Kingdom
    PLoS ONE 6:e21827. 2011

Detail Information

Publications73

  1. doi request reprint New staging system: how does it affect our practice?
    Peter Goldstraw
    National Heart and Lung Institute, Imperial College, London, United Kingdom
    J Clin Oncol 31:984-91. 2013
    ..In this article, the changes to the classification are described, and their possible impacts on clinical care and research are discussed...
  2. doi request reprint Updated staging system for lung cancer
    Peter Goldstraw
    Academic Department of Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Surg Oncol Clin N Am 20:655-66. 2011
    ..There have been changes to certain tumor and metastasis descriptors and the resultant stage groupings. This article describes these changes, provides more in-depth discussion of the changes, and provides much additional information...
  3. ncbi request reprint The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours
    Peter Goldstraw
    Royal Brompton Hospital, Imperial College, London, United Kingdom
    J Thorac Oncol 2:706-14. 2007
    ..The recommendations of this committee for changes to the T, N, and M descriptors have been published. This report contains the proposals for the new stage groupings...
  4. ncbi request reprint A prospective, randomized, controlled trial of the effectiveness of BioGlue in treating alveolar air leaks
    Patrick Tansley
    Department of Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London, United Kingdom
    J Thorac Cardiovasc Surg 132:105-12. 2006
    ..The aim of this study was to determine the effectiveness of BioGlue (CryoLife Europa Ltd, Hampshire, United Kingdom) in eliminating post-thoracotomy alveolar air leaks...
  5. doi request reprint Non-small-cell lung cancer
    Peter Goldstraw
    Academic Department of Thoracic Surgery, Royal Brompton and Harefield NHS Foundation Trust, Imperial College School of Medicine, London, UK
    Lancet 378:1727-40. 2011
    ....
  6. doi request reprint A prospective, randomized trial comparing BioGlue and Vivostat for the control of alveolar air leak
    Elizabeth Belcher
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 140:32-8. 2010
    ..Vivostat (Vivostat A/S, Alleroed, Denmark) is an autologous fibrin sealant that confers certain advantages. It shows superior elastic properties, a faster absorption time, and the absence of risk of transmission of blood-borne diseases...
  7. doi request reprint The role of surgery in the treatment of limited disease small cell lung cancer: time to reevaluate
    Eric Lim
    Imperial College and Academic Division of Thoracic Surgery and Histopathology, Royal Brompton Hospital, London, UK
    J Thorac Oncol 3:1267-71. 2008
    ..Controversy remains as to when surgery should be considered. We sought to determine the survival after complete resection of SCLC and the prognostic impact of clinical and pathologic stage...
  8. doi request reprint The frequency of neuroendocrine cell hyperplasia in patients with pulmonary neuroendocrine tumours and non-neuroendocrine cell carcinomas
    Selim M H Rizvi
    Department of Histopathology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Histopathology 55:332-7. 2009
    ..To evaluate the frequency of neuroendocrine cell hyperplasia (NEH) in resected neuroendocrine tumours and non-neuroendocrine cell carcinomas and to study its relationship to selected clinical parameters...
  9. pmc Assessment of cell line models of primary human cells by Raman spectral phenotyping
    Robin J Swain
    Department of Materials, Imperial College London, London, United Kingdom
    Biophys J 98:1703-11. 2010
    ..The findings have far-reaching implications for the assessment of cell lines as suitable primary cellular models in live cultures...
  10. pmc Innate immune responses to bacterial ligands in the peripheral human lung--role of alveolar epithelial TLR expression and signalling
    Andrew J Thorley
    Lung Cell Biology, Section of Pharmacology and Toxicology, National Heart and Lung Institute, Imperial College, London, United Kingdom
    PLoS ONE 6:e21827. 2011
    ....
  11. ncbi request reprint Feasibility of the detection of the sentinel lymph node in peripheral non-small cell lung cancer with radio isotopic and blue dye techniques
    Olivier Tiffet
    FRCS, Department of Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK
    Chest 127:443-8. 2005
    ....
  12. ncbi request reprint Intraoperative pleural lavage cytology is an independent prognostic indicator for staging non-small cell lung cancer
    Eric Lim
    Department of Thoracic Surgery, Royal Brompton Hospital, London, UK
    J Thorac Cardiovasc Surg 127:1113-8. 2004
    ..To ascertain the frequency and quantify the effect of this finding on survival, we performed a prospective study of intraoperative pleural lavage cytology...
  13. doi request reprint Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer
    Khaled M Sarraf
    Academic Division of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 137:425-8. 2009
    ..We sought to determine factors associated with increasing neutrophil/lymphocyte ratios and the stage-adjusted prognostic effect in patients undergoing resection for non-small cell lung cancer...
  14. doi request reprint Secondary vascular changes in pulmonary sequestrations
    Saral Desai
    Department of Histopathology, Royal Brompton and Harefield NHS Trust, London, UK
    Histopathology 57:121-7. 2010
    ..The aim of this study was to retrospectively review morphological changes within sequestrations, concentrating on vascular changes and associations with clinical parameters...
  15. ncbi request reprint Differential regulation of cytokine release and leukocyte migration by lipopolysaccharide-stimulated primary human lung alveolar type II epithelial cells and macrophages
    Andrew J Thorley
    Lung Cell Biology, Section of Airways Disease, National Heart and Lung Institute, Imperial College, London, United Kingdom
    J Immunol 178:463-73. 2007
    ....
  16. pmc Physiological properties of human diaphragm muscle fibres and the effect of chronic obstructive pulmonary disease
    Alison K Stubbings
    Molecular Medicine Section, National Heart and Lung Institute, Imperial College London, South Kensington Campus, London SW7 2AZ, UK
    J Physiol 586:2637-50. 2008
    ....
  17. doi request reprint Reducing cardiac injury during minimally invasive repair of pectus excavatum
    Elizabeth Belcher
    Department of Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London SW3 6NP, United Kingdom
    Eur J Cardiothorac Surg 33:931-3. 2008
    ..Cardiovascular complications represent a rare but catastrophic complication of this cosmetic operation. We describe a modification to the technique following a case of cardiac puncture...
  18. pmc Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake
    Sarah J Kemp
    Lung Cell Biology, National Heart and Lung Institute, Imperial College, London, UK
    Am J Respir Cell Mol Biol 39:591-7. 2008
    ..AT1 cells could be important in translocation of particles from the lung into the circulation...
  19. pmc Spectral monitoring of surfactant clearance during alveolar epithelial type II cell differentiation
    Robin J Swain
    Department of Materials and Institute of Biomedical Engineering, Imperial College London, London, United Kingdom
    Biophys J 95:5978-87. 2008
    ..These results demonstrate the first spectral characterization of primary human ATII cells, and provide insight into the biochemical properties of alveolar surfactant in its unperturbed cellular environment...
  20. ncbi request reprint Thyroid transcription factor 1 immunohistochemistry as an intraoperative diagnostic tool at frozen section for distinction between primary and secondary lung tumors
    David N Butcher
    Department of Histopathology, Royal Brompton Hospital, London SW3 6NP, United Kingdom
    Arch Pathol Lab Med 131:582-7. 2007
    ..Intraoperative distinction between primary and metastatic carcinomas in the lung at frozen section remains problematic...
  21. doi request reprint Unilateral extrapulmonary airway bypass in advanced emphysema
    Alastair J Moore
    Department of Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, United Kingdom
    Ann Thorac Surg 89:899-906, 906.e1-2. 2010
    ..We tested the hypothesis that a direct connection between the lung parenchyma and the atmosphere could increase expiratory flow and thereby potentially improve dyspnea through the relief of gas trapping...
  22. doi request reprint Proceedings of the IASLC International Workshop on Advances in Pulmonary Neuroendocrine Tumors 2007
    Eric Lim
    Imperial College and the Academic Division of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Oncol 3:1194-201. 2008
    ....
  23. ncbi request reprint Cystic lung lesions in the pediatric and adult population: surgical experience at the Brompton Hospital
    Konstantinos Papagiannopoulos
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 73:1594-8. 2002
    ..Cystic lung lesions are found in the adult and pediatric populations. We present our 19-year experience with such lesions from a single institution...
  24. doi request reprint Prognostic factors for survival after surgical palliation of malignant pleural effusion
    John E Pilling
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Oncol 5:1544-50. 2010
    ..To investigate prognostic factors for patient survival after surgical palliation of malignant pleural effusion (MPE)...
  25. ncbi request reprint Invited commentary
    Peter Goldstraw
    Department of Thoracic Surgery, Royal Brompton Hospital, Sydney St, London, SW3 6NP United Kingdom
    Ann Thorac Surg 83:1849. 2007
  26. ncbi request reprint Idiopathic tracheal and bronchial stenosis in two pediatric patients
    Emma Beddow
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 77:1829-32. 2004
    ..Here we report two pediatric cases, one with the rarer condition of idiopathic bronchial stenosis, and we discuss the management and histopathologic findings...
  27. ncbi request reprint The impact of stage and cell type on the prognosis of pulmonary neuroendocrine tumors
    Eric Lim
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 130:969-72. 2005
    ..To clarify this relationship, we studied patients treated at our institution over a 23-year period...
  28. ncbi request reprint Nuss procedure improves the quality of life in young male adults with pectus excavatum deformity
    George Krasopoulos
    Royal Brompton Hospital, Department of Thoracic Surgery, Sydney Street, London SW3 6NP, UK
    Eur J Cardiothorac Surg 29:1-5. 2006
    ..The Nuss procedure is a minimally invasive pectus repair. This study represents an attempt towards exploring the changes in quality of life and overall satisfaction in young male adults who underwent a Nuss procedure...
  29. ncbi request reprint Passive properties of the diaphragm in COPD
    Alastair J Moore
    Respiratory Muscle Laboratory, Royal Brompton Hospital and National Heart Lung Institute, London SW3 6NP, UK
    J Appl Physiol 101:1400-5. 2006
    ..This may assist the muscle with the energetic changes in the length of the diaphragm required during breathing in COPD...
  30. doi request reprint The mortality from acute respiratory distress syndrome after pulmonary resection is reducing: a 10-year single institutional experience
    Sarah S K Tang
    Department of Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London SW36NP, UK
    Eur J Cardiothorac Surg 34:898-902. 2008
    ..Ann Thorac Surg 2000;69:376-80]. The current study compares our recent experience with this historical data to assess if improved recognition of ARDS and treatment strategies has had an impact on the incidence and mortality...
  31. ncbi request reprint Large cell neuroendocrine carcinoma and large cell carcinomas with neuroendocrine morphology of the lung: prognosis after complete resection and systematic nodal dissection
    Joseph Zacharias
    Department of Thoracic Surgery and Histopathology, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 75:348-52. 2003
    ..We retrospectively reviewed a cohort of patients at our institution who had this type of tumor to determine factors that might influence survival...
  32. ncbi request reprint Tracheobronchial obstruction in children: experience with endoscopic airway stenting
    Pankaj Kumar
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 75:1579-86. 2003
    ..We reviewed our experience to determine the role of endoscopic airway stents in children with tracheobronchial obstruction...
  33. ncbi request reprint An assessment of the expanded classification of congenital cystic adenomatoid malformations and their relationship to malignant transformation
    Fergus Macsweeney
    Department of Histopathology, Royal Brompton Hospital, London, UK
    Am J Surg Pathol 27:1139-46. 2003
    ..However, stromal cellularity in a type 4 CCAM should raise the possibility of blastomatous transformation...
  34. ncbi request reprint Surgery for small cell lung cancer
    Michael Dusmet
    The Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Hematol Oncol Clin North Am 18:323-41. 2004
  35. ncbi request reprint A clinicopathologic study of 12 neuroendocrine tumors arising in the thymus
    Olivier Tiffet
    Department of Thoracic Surgery, Royal Brompton Hospital, London, UK
    Chest 124:141-6. 2003
    ..To determine whether the new classification system for thymic carcinoid tumors/neuroendocrine carcinomas provides prognostic data, and to study the presentation, diagnosis, treatment, and prognostic factors of these rare tumors...
  36. ncbi request reprint Primary human alveolar type II epithelial cell CCL20 (macrophage inflammatory protein-3alpha)-induced dendritic cell migration
    Andrew J Thorley
    Lung Cell Biology, National Heart and Lung Institute, Imperial College, Dovehouse Street, London SW3 6LY, UK
    Am J Respir Cell Mol Biol 32:262-7. 2005
    ....
  37. ncbi request reprint Fixed and dynamic airway obstruction in polychondritis
    Babu T Muntimadugu
    Department of Thoracic Surgery, Royal Brompton Hospital, London SW3 6NP, UK
    Eur J Cardiothorac Surg 27:705. 2005
  38. ncbi request reprint Invited commentary
    Simon Jordan
    Department of Thoracic Surgery, Royal Brompton Hospital, Sydney St, London, SW3 6NP United Kingdom
    Ann Thorac Surg 83:1139. 2007
  39. doi request reprint Limb salvage surgery in the excision of a massive fibromatosis
    Karen C Redmond
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 92:e53-5. 2011
    ..Function and structure preserving procedures are important as the primary goal, if not even more important...
  40. ncbi request reprint Prolonged survival due to spontaneous regression and surgical excision of malignant mesothelioma
    John E Pilling
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 83:314-5. 2007
    ..During a 12-year follow-up there was a single recurrence, which was a lesion in the chest wall at 6 years that was surgically excised. A prominent host response to tumor was seen in both the primary tumor and the recurrence...
  41. ncbi request reprint Inter-observer variability in systematic nodal dissection: comparison of European and Japanese nodal designation
    Shun ichi Watanabe
    Department of Thoracic Surgery, Royal Brompton Hospital, London, England
    Ann Thorac Surg 73:245-8; discussion 248-9. 2002
    ..The objective of this study was to assess the inter-observer variability in the interpretation of lymph node stations...
  42. ncbi request reprint Invited commentary
    Peter Goldstraw
    Department of Thoracic Surgery, Royal Brompton Hospital, Sydney St, London, SW3 6NP, United Kingdom
    Ann Thorac Surg 80:2324-5. 2005
  43. ncbi request reprint Effect of bronchoscopic lung volume reduction on dynamic hyperinflation and exercise in emphysema
    Nicholas S Hopkinson
    Respiratory Muscle Laboratory, Department of Respiratory Medicine, Royal Brompton Hospital, Fulham Road, London SW3 6NP, UK
    Am J Respir Crit Care Med 171:453-60. 2005
    ..47; p = 0.03). Endobronchial valve placement can improve lung volumes and gas transfer in patients with chronic obstructive pulmonary disease and prolong exercise time by reducing dynamic hyperinflation...
  44. ncbi request reprint Intrapleural tumor dissemination after video-assisted thoracoscopic surgery metastasectomy
    Keng Leong Ang
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 75:1643-5. 2003
    ..This case highlights tumor dissemination as one of the pitfalls of VATS metastasectomy and raises concerns about using VATS in this situation...
  45. ncbi request reprint Asymmetric ARDS following pulmonary resection: CT findings initial observations
    Simon P G Padley
    Department of Radiology, Royal Brompton Hospital, Fulham Rd, London SW3 6NP, England
    Radiology 223:468-73. 2002
    ....
  46. ncbi request reprint Variation in iron homeostasis genes between patients with ARDS and healthy control subjects
    Anna L Lagan
    Unit of Critical Care, Royal Brompton Hospital, London, UK
    Chest 133:1302-11. 2008
    ..Evidence suggests that genetic predisposition is relevant to the pathogenesis of ARDS. We therefore explored the hypothesis that polymorphisms from a panel of genes encoding iron-metabolizing proteins determine susceptibility to ARDS...
  47. ncbi request reprint Mediastinoscopy and mediastinotomy after cardiac surgery: are safety and efficacy affected by prior sternotomy?
    Pankaj Kumar
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 76:872-6; discussion 876-7. 2003
    ..Left anterior mediastinotomy is of further value in assessing left upper lobe tumors. However the efficacy and safety of both these procedures after median sternotomy for cardiac surgery is unknown...
  48. ncbi request reprint Airway obstruction and ventilator dependency in young children with congenital cardiac defects: a role for self-expanding metal stents
    Pankaj Kumar
    Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Intensive Care Med 28:190-5. 2002
    ..Young children with congenital cardiac defect and airway obstruction leading to ventilator dependency present a significant clinical challenge with uncertain outcome...
  49. ncbi request reprint Plombage thoracoplasty with Lucite balls
    Cagatay Saim Tezel
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 79:1063. 2005
  50. ncbi request reprint Primary human alveolar type II epithelial cell chemokine release: effects of cigarette smoke and neutrophil elastase
    Ian R Witherden
    Lung Cell Biology, National Heart and Lung Institute, Imperial College of Science, London, United Kingdom
    Am J Respir Cell Mol Biol 30:500-9. 2004
    ..We hypothesize that reduced ATII cell-derived chemokine levels compromise alveolar repair, contributing to cigarette smoke-induced alveolar damage and emphysema...
  51. ncbi request reprint Liposarcoma of the thyroid gland mimicking retrosternal goiter
    Wael I Awad
    Department of Thoracic Surgery, Royal Brompton Hospital, London, England
    Ann Thorac Surg 75:566-8. 2003
    ..Patient 2 had a long-term history of benign goiter, a previous partial thyroidectomy, and more recent biopsies showing liposarcoma. The management of such rare conditions is always challenging...
  52. ncbi request reprint Abdominal compartment syndrome: a rare complication of plication of the diaphragm
    Joideep Phadnis
    Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom
    Ann Thorac Surg 82:334-6. 2006
    ..We believe this is the only report of this complication after diaphragmatic plication and one of very few reported thoracic causes of abdominal compartment syndrome...
  53. ncbi request reprint Frequency and prognostic significance of preoperatively detected enlarged regional lymph nodes in patients with pathological stage I non-small cell lung cancer following resection
    Jenny K Hoang
    Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA
    J Thorac Oncol 2:1103-6. 2007
    ..To explore the clinical significance of enlarged regional lymph nodes in patients with pathological stage I non-small cell lung cancer (NSCLC)...
  54. ncbi request reprint Surgery for bronchioloalveolar carcinoma and "very early" adenocarcinoma: an evolving standard of care?
    Valerie W Rusch
    Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 1:S27-31. 2006
    ..To improve our management of very early AC, much more information is needed about the molecular abnormalities of AC and their relationship to clinical outcomes...
  55. ncbi request reprint The IASLC Lung Cancer Staging Project: proposals for the revision of the T descriptors in the forthcoming (seventh) edition of the TNM classification for lung cancer
    Ramon Rami-Porta
    Thoracic Surgery Service, Hospital Mutua de Terrassa, Terrassa, Barcelona, Spain
    J Thorac Oncol 2:593-602. 2007
    ..To propose changes in the seventh revision of the tumor, node, metastasis (TNM) classification for lung cancer...
  56. ncbi request reprint Value of intraoperative pleural lavage in staging non-small cell lung cancer
    Peter Goldstraw
    J Thorac Cardiovasc Surg 128:331. 2004
  57. ncbi request reprint Is radical mediastinal dissection mandatory for curative resection of NSCLC?
    Elizabeth Belcher
    Eur J Cardiothorac Surg 31:142-3; author reply 143-4. 2007
  58. ncbi request reprint The IASLC Lung Cancer Staging Project: proposals for the revision of the N descriptors in the forthcoming seventh edition of the TNM classification for lung cancer
    Valerie W Rusch
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 2:603-12. 2007
    ..We sought to determine whether the current N descriptors should be maintained or revised for the next edition of the international lung cancer staging system...
  59. ncbi request reprint Surgical sealants for air leaks after pulmonary surgery
    Eric Lim
    Eur J Cardiothorac Surg 32:552-3. 2007
  60. ncbi request reprint Gene expression signature for angiogenic and nonangiogenic non-small-cell lung cancer
    Jiangting Hu
    Cancer Research UK Tumour Pathology Group, Nuffield Department of Clinical Laboratory Science, University of Oxford, John Radcliffe Hospital, Headington OX3 9DU, Oxford, UK
    Oncogene 24:1212-9. 2005
    ..We raise the hypothesis that in nonangiogenic tumours, hypoxia leads to a higher activation of the mitochondrial respiratory chain, which allows tumour growth without triggering angiogenesis...
  61. ncbi request reprint Complete resection in lung cancer surgery: proposed definition
    Ramon Rami-Porta
    Complete Resection Subcommittee of the IASLC Staging Committee, Thoracic Surgery Service, Hospital Mutua de Terrassa, University of Barcelona, Plaza Dr Robert, 5, 08221 Terrassa, Barcelona, Spain
    Lung Cancer 49:25-33. 2005
    ..To propose an internationally accepted definition of complete resection in lung cancer surgery...
  62. ncbi request reprint The IASLC Lung Cancer Staging Project: validation of the proposals for revision of the T, N, and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
    Patti A Groome
    Queen s Cancer Research Institute, Kingston, Ontario, Canada
    J Thorac Oncol 2:694-705. 2007
    ..In this article, we describe the methods and validation approaches used and discuss the internal and external validity of the recommended changes...
  63. doi request reprint The impact of additional prognostic factors on survival and their relationship with the anatomical extent of disease expressed by the 6th Edition of the TNM Classification of Malignant Tumors and the proposals for the 7th Edition
    Jean Paul Sculier
    Institut Jules Bordet, Universite Libre de Bruxelles ULB, Brussels, Belgium
    J Thorac Oncol 3:457-66. 2008
    ..To identify, in the international staging database of the International Association for the Study of Lung Cancer, those prognostic factors that were significant and independent of clinical stage...
  64. ncbi request reprint Selection of patients for surgery after induction chemotherapy for N2 non-small-cell lung cancer
    Peter Goldstraw
    J Clin Oncol 24:3317-8. 2006
  65. ncbi request reprint The IASLC Lung Cancer Staging Project: proposals for revision of the M descriptors in the forthcoming (seventh) edition of the TNM classification of lung cancer
    Pieter E Postmus
    Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    J Thorac Oncol 2:686-93. 2007
    ..To analyze all nonlymphatic metastatic components (T4 and M1) of the current TNM system of lung cancer, with the objective of providing suggestions for the next edition of the TNM classification for lung cancer...
  66. ncbi request reprint The International Association for the Study of Lung Cancer lung cancer staging project: proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancer
    Frances A Shepherd
    Department of Medicine, Division of Medical Oncology and Hematology of the University Health Network, Princess Margaret Hospital and the University of Toronto, Ontario, Canada
    J Thorac Oncol 2:1067-77. 2007
    ..The current analysis looks to the impact of the TNM system on the clinical staging of SCLC and of the new International Association for the study of Lung Cancer (IASLC) proposals...
  67. ncbi request reprint Results of lung metastasectomy from breast cancer: prognostic criteria on the basis of 467 cases of the International Registry of Lung Metastases
    Godehard Friedel
    Department of Thoracic Surgery, Klink Schillerhoehe, Solitudestrasse 18, D 70839 Gerlingen, Germany
    Eur J Cardiothorac Surg 22:335-44. 2002
    ..Although the prognosis after resection of isolated metastases to the lung is much better than after chemotherapy most oncologists and gynecologists disapprove of lung metastasectomy...
  68. pmc Recurrent KRAS codon 146 mutations in human colorectal cancer
    Sarah Edkins
    Cancer Genome Project, Welcome Trust Sanger Institute, Hinxton, UK
    Cancer Biol Ther 5:928-32. 2006
    ....
  69. ncbi request reprint Preoperative chemotherapy in patients with resectable non-small cell lung cancer: results of the MRC LU22/NVALT 2/EORTC 08012 multicentre randomised trial and update of systematic review
    David Gilligan
    Addenbrooke s Hospital, Cambridge, UK
    Lancet 369:1929-37. 2007
    ....
  70. ncbi request reprint Detecting lung cancer in plasma with the use of multiple genetic markers
    Francesca Andriani
    Department of Experimental Oncology, Istituto Nazionale Tumori, Milan, Italy
    Int J Cancer 108:91-6. 2004
    ..2%) of stage I patients whose tumors had an alteration. These results provide the proof of principle that plasma DNA alterations are tumor-specific in most cases and support blood testing as a noninvasive strategy for early detection...
  71. ncbi request reprint Somatic mutations of the protein kinase gene family in human lung cancer
    Helen Davies
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, United Kingdom
    Cancer Res 65:7591-5. 2005
    ..The results suggest that several mutated protein kinases may be contributing to lung cancer development, but that mutations in each one are infrequent...
  72. ncbi request reprint Somatic genetic changes accompanying lung tumor development
    Nicola A Foster
    MRC Molecular Oncology Group, Department of Oncology, University of Cambridge, MRC Centre, Cambridge, United Kingdom
    Genes Chromosomes Cancer 44:65-75. 2005
    ..demonstration of sequential genetic changes raises the possibility that this approach, unencumbered by interpatient variability between lesions, will greatly facilitate the identification of molecular events driving the invasive process..
  73. ncbi request reprint Lung cancer: intragenic ERBB2 kinase mutations in tumours
    Philip Stephens
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK
    Nature 431:525-6. 2004
    ..ERBB2 inhibitors, which have so far proved to be ineffective in treating lung cancer, should now be clinically re-evaluated in the specific subset of patients with lung cancer whose tumours carry ERBB2 mutations...