S R Durham

Summary

Affiliation: Royal Brompton Hospital
Country: UK

Publications

  1. ncbi Long-term clinical efficacy of grass-pollen immunotherapy
    S R Durham
    Department of Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, United Kingdom
    N Engl J Med 341:468-75. 1999
  2. ncbi Grass pollen immunotherapy: symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season
    D R Wilson
    Department of Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, Dovehouse St, London, SW3 6LY, UK
    J Allergy Clin Immunol 107:971-6. 2001
  3. ncbi Basophil recruitment and IL-4 production during human allergen-induced late asthma
    K T Nouri-Aria
    Department of Upper Respiratory Medicine, Imperial College at National Heart and Lung Institute and Royal Brompton Hospital, London, United Kingdom
    J Allergy Clin Immunol 108:205-11. 2001
  4. ncbi Grass pollen immunotherapy for seasonal rhinitis and asthma: a randomized, controlled trial
    S M Walker
    Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK
    J Allergy Clin Immunol 107:87-93. 2001
  5. ncbi Grass pollen immunotherapy inhibits seasonal increases in basophils and eosinophils in the nasal epithelium
    D R Wilson
    Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK
    Clin Exp Allergy 31:1705-13. 2001
  6. ncbi Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
    V A Varney
    Department of Allergy and Clinical Immunology, National Heart and Lung Institute, London, United Kingdom
    J Clin Invest 92:644-51. 1993

Collaborators

Detail Information

Publications6

  1. ncbi Long-term clinical efficacy of grass-pollen immunotherapy
    S R Durham
    Department of Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, United Kingdom
    N Engl J Med 341:468-75. 1999
    ..Pollen immunotherapy is effective in selected patients with IgE-mediated seasonal allergic rhinitis, although it is questionable whether there is long-term benefit after the discontinuation of treatment...
  2. ncbi Grass pollen immunotherapy: symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season
    D R Wilson
    Department of Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, Dovehouse St, London, SW3 6LY, UK
    J Allergy Clin Immunol 107:971-6. 2001
    ..6, P <.02) correlated with symptoms after immunotherapy. CONCLUSION: Improvement in symptoms after grass pollen immunotherapy may result, at least in part, from inhibition of IL-5-dependent tissue eosinophilia during the pollen season...
  3. ncbi Basophil recruitment and IL-4 production during human allergen-induced late asthma
    K T Nouri-Aria
    Department of Upper Respiratory Medicine, Imperial College at National Heart and Lung Institute and Royal Brompton Hospital, London, United Kingdom
    J Allergy Clin Immunol 108:205-11. 2001
    ....
  4. ncbi Grass pollen immunotherapy for seasonal rhinitis and asthma: a randomized, controlled trial
    S M Walker
    Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK
    J Allergy Clin Immunol 107:87-93. 2001
    ..CONCLUSION: Grass pollen immunotherapy improves quality of life in seasonal allergic rhinitis and reduces seasonal asthma symptoms and bronchial hyperresponsiveness...
  5. ncbi Grass pollen immunotherapy inhibits seasonal increases in basophils and eosinophils in the nasal epithelium
    D R Wilson
    Upper Respiratory Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK
    Clin Exp Allergy 31:1705-13. 2001
    ..Immunotherapy may act, at least in part, by reducing seasonal recruitment of basophils and eosinophils into the epithelium...
  6. ncbi Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
    V A Varney
    Department of Allergy and Clinical Immunology, National Heart and Lung Institute, London, United Kingdom
    J Clin Invest 92:644-51. 1993
    ..The results support the view that immunotherapy may possibly be working through induction of T cell tolerance...