Affiliation: Royal Brompton Hospital
- The addition of mechanical insufflation/exsufflation shortens airway-clearance sessions in neuromuscular patients with chest infectionMichelle Chatwin
Academic and Clinical Department of Sleep and Breathing, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, United Kingdom
Respir Care 54:1473-9. 2009..We hypothesized that airway clearance in these patients would be more effective with in-exsufflation, compared to without in-exsufflation...
- High-frequency chest-wall oscillation in a noninvasive-ventilation-dependent patient with type 1 spinal muscular atrophyJoanna M Keating
Department of Physiotherapy, Brompton Hospital, London, UK
Respir Care 56:1840-3. 2011..In a patient with neuromuscular disease and severe respiratory infection and compromise, HFCWO can be used safely in combination with conventional secretion-clearance physiotherapy...
- Risk management protocol for gastrostomy and jejunostomy insertion in ventilator dependent infantsM Chatwin
Clinical and Academic Department of Sleep and Breathing, Royal Brompton and Harefield NHS Foundation Trust, United Kingdom
Neuromuscul Disord 23:289-97. 2013..Additionally this protocol can minimise post-operative complications and is associated with a good outcome in the majority...
- Randomised trial of inpatient versus outpatient initiation of home mechanical ventilation in patients with nocturnal hypoventilationMichelle Chatwin
Sleep and Ventilation Unit, Academic and Clinical Department of Sleep and Breathing, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
Respir Med 102:1528-35. 2008..Long-term home mechanical ventilation (HMV) is usually initiated in hospital. Admission to hospital has resource implications and may not be reimbursable in some healthcare systems...
- Analysis of home support and ventilator malfunction in 1,211 ventilator-dependent patientsM Chatwin
Sleep and Ventilation Unit, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK
Eur Respir J 35:310-6. 2010..Where no fault can be found during an equipment check, the patient themselves may be unwell and should receive early clinical evaluation. The patient may have mistaken clinical deterioration for an equipment problem...
- Outcome of goal-directed non-invasive ventilation and mechanical insufflation/exsufflation in spinal muscular atrophy type IM Chatwin
Sleep and Ventilation Unit, Clinical and Academic Department of Sleep and Breathing, Royal Brompton Hospital, Sydney Street, London, UK
Arch Dis Child 96:426-32. 2011..There are widely discrepant views on the respiratory management of infants with spinal muscular atrophy (SMA) type I. Typically, management is palliative...
- Randomized trial of 'intelligent' autotitrating ventilation versus standard pressure support non-invasive ventilation: impact on adherence and physiological outcomesJulia L Kelly
Sleep and Ventilation Department, NIHR Respiratory Disease Biomedical Research Unit at the Royal Brompton and Harefield NHS Foundation Trust and National Heart and Lung Institute, Imperial College London, London, UK
Respirology 19:596-603. 2014....
- Long term non-invasive ventilation in children: impact on survival and transition to adult careMichelle Chatwin
Academic and Clinical Department of Sleep and Breathing, Royal Brompton and Harefield NHS Foundation Trust, Sydney Street, London, United Kingdom NIHR Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, Sydney Street, London, United Kingdom
PLoS ONE 10:e0125839. 2015..However, the outcome of this intervention and the number of children transitioning to adult care as a consequence of longer survival is not yet clear...
- Exercise-induced depression of the diaphragm motor evoked potential is not affected by non-invasive ventilationMark J Dayer
Respiratory Muscle Laboratory, Royal Brompton Hospital, London SW3 6NP, United Kingdom
Respir Physiol Neurobiol 155:243-54. 2007..098). We conclude that the work of breathing during whole body exercise is not the primary driver of exercise-induced diaphragm MEP depression...