Diana Bilton

Summary

Affiliation: Royal Brompton Hospital
Country: UK

Publications

  1. pmc What did we learn from the North American Cystic Fibrosis Conference?
    Diana Bilton
    Department of Respiratory Medicine, Royal Brompton Hospital Sydney Street, London SW3 6NP, UK
    J R Soc Med 101:S6-9. 2008
  2. ncbi Fertility issues in cystic fibrosis
    Angela Lyon
    Adult CF Centre, Papworth Hospital NHS Trust, Cambridge, UK
    Paediatr Respir Rev 3:236-40. 2002
  3. ncbi End of life care for adult cystic fibrosis patients: facilitating a good enough death
    Elizabeth Chapman
    Adult Cystic Fibrosis Centre, Papworth NHS Trust, Papworth Everard, Cambridge CB3 8RE United Kingdom
    J Cyst Fibros 4:249-57. 2005
  4. ncbi Managing adults with cystic fibrosis
    Diana Bilton
    Adult Cystic Fibrosis Centre, Papworth Hospital NHS Foundation Trust, Cambridge
    Practitioner 251:46, 48, 50 passim. 2007
  5. doi Update on non-cystic fibrosis bronchiectasis
    Diana Bilton
    Royal Brompton Hospital, Sydney Street, London, UK
    Curr Opin Pulm Med 14:595-9. 2008
  6. doi Phase 3 randomized study of the efficacy and safety of inhaled dry powder mannitol for the symptomatic treatment of non-cystic fibrosis bronchiectasis
    Diana Bilton
    Department of Respiratory Medicine, Royal Brompton Hospital, London, England
    Chest 144:215-25. 2013
  7. doi Pooled analysis of two large randomised phase III inhaled mannitol studies in cystic fibrosis
    Diana Bilton
    Royal Brompton Hospital, London, United Kingdom
    J Cyst Fibros 12:367-76. 2013
  8. doi Pulmonary exacerbation: towards a definition for use in clinical trials. Report from the EuroCareCF Working Group on outcome parameters in clinical trials
    D Bilton
    Royal Brompton Hospital, Respiratory Medicine, London, UK
    J Cyst Fibros 10:S79-81. 2011
  9. doi Inhaled dry powder mannitol in cystic fibrosis: an efficacy and safety study
    D Bilton
    Royal Brompton Hospital, London, SW3 6NP, UK
    Eur Respir J 38:1071-80. 2011
  10. doi Inhaled mannitol for the treatment of cystic fibrosis
    Katharine Hurt
    Department of Cystic Fibrosis, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK
    Expert Rev Respir Med 6:19-26. 2012

Collaborators

Detail Information

Publications24

  1. pmc What did we learn from the North American Cystic Fibrosis Conference?
    Diana Bilton
    Department of Respiratory Medicine, Royal Brompton Hospital Sydney Street, London SW3 6NP, UK
    J R Soc Med 101:S6-9. 2008
  2. ncbi Fertility issues in cystic fibrosis
    Angela Lyon
    Adult CF Centre, Papworth Hospital NHS Trust, Cambridge, UK
    Paediatr Respir Rev 3:236-40. 2002
    ..For females, successful pregnancy is possible but careful planning is required. The practical and ethical aspects of reproductive health in CF are discussed...
  3. ncbi End of life care for adult cystic fibrosis patients: facilitating a good enough death
    Elizabeth Chapman
    Adult Cystic Fibrosis Centre, Papworth NHS Trust, Papworth Everard, Cambridge CB3 8RE United Kingdom
    J Cyst Fibros 4:249-57. 2005
    ..This study examined how a number of recent deaths have been handled in an adult CF centre in the UK...
  4. ncbi Managing adults with cystic fibrosis
    Diana Bilton
    Adult Cystic Fibrosis Centre, Papworth Hospital NHS Foundation Trust, Cambridge
    Practitioner 251:46, 48, 50 passim. 2007
  5. doi Update on non-cystic fibrosis bronchiectasis
    Diana Bilton
    Royal Brompton Hospital, Sydney Street, London, UK
    Curr Opin Pulm Med 14:595-9. 2008
    ..There has been debate regarding the requirement for investigations to establish an underlying cause of bronchiectasis. Furthermore, there has been growing interest in establishing the role of bacteria in disease progression...
  6. doi Phase 3 randomized study of the efficacy and safety of inhaled dry powder mannitol for the symptomatic treatment of non-cystic fibrosis bronchiectasis
    Diana Bilton
    Department of Respiratory Medicine, Royal Brompton Hospital, London, England
    Chest 144:215-25. 2013
    ..Inhaled dry powder mannitol enhanced mucus clearance and improved quality of life over 2 weeks in non-cystic fibrosis bronchiectasis. This study's objective was to investigate the efficacy and safety of dry powder mannitol over 12 weeks...
  7. doi Pooled analysis of two large randomised phase III inhaled mannitol studies in cystic fibrosis
    Diana Bilton
    Royal Brompton Hospital, London, United Kingdom
    J Cyst Fibros 12:367-76. 2013
    ..To evaluate safety and efficacy of inhaled mannitol treatment in subgroups of a large global CF population...
  8. doi Pulmonary exacerbation: towards a definition for use in clinical trials. Report from the EuroCareCF Working Group on outcome parameters in clinical trials
    D Bilton
    Royal Brompton Hospital, Respiratory Medicine, London, UK
    J Cyst Fibros 10:S79-81. 2011
    ..Which parameters to include as well as the problems associated with the use of scoring systems and symptom clusters are being discussed...
  9. doi Inhaled dry powder mannitol in cystic fibrosis: an efficacy and safety study
    D Bilton
    Royal Brompton Hospital, London, SW3 6NP, UK
    Eur Respir J 38:1071-80. 2011
    ..Mannitol showed sustained, clinically meaningful benefit in airway function in CF, irrespective of concomitant rhDNase use. Mannitol appears to have an acceptable safety profile for patients with CF...
  10. doi Inhaled mannitol for the treatment of cystic fibrosis
    Katharine Hurt
    Department of Cystic Fibrosis, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK
    Expert Rev Respir Med 6:19-26. 2012
    ..Its formulation as a dry powder makes it quick and convenient to take...
  11. doi Quantification of neutrophil migration into the lungs of patients with chronic obstructive pulmonary disease
    Prina Ruparelia
    Department of Respiratory Medicine, University of Cambridge School of Clinical Medicine, Cambridge, UK
    Eur J Nucl Med Mol Imaging 38:911-9. 2011
    ..To quantify neutrophil migration into the lungs of patients with chronic pulmonary obstructive disease (COPD)...
  12. doi Primary care summary of the British Thoracic Society Guideline on the management of non-cystic fibrosis bronchiectasis
    Adam T Hill
    Department of Respiratory Medicine, Royal Infirmary and University of Edinburgh, Scotland, UK
    Prim Care Respir J 20:135-40. 2011
    ..Management in primary care is aimed at improving morbidity, and includes; patient education, treatment and monitoring, as well as appropriate referral to secondary care including assessment for long term antibiotics...
  13. doi Predictors of outcome in patients with cystic fibrosis requiring endotracheal intubation
    Andrew Jones
    Department of Cystic Fibrosis, Royal Brompton Hospital, London, UK
    Respirology 18:630-6. 2013
    ....
  14. ncbi Bugs, biofilms, and resistance in cystic fibrosis
    Jane C Davies
    Department of Gene Therapy, Imperial College, Emmanuel Kaye Building, Manresa Road, London SW3 6NP, United Kingdom
    Respir Care 54:628-40. 2009
    ..Future work should aim to develop clinically applicable methods to identify these and to determine which have the potential to impact pulmonary health. We outline the basic tenets of infection control and treatment...
  15. doi Oral contraceptives do not appear to affect cystic fibrosis disease severity
    Natalie G Kernan
    Dept of Gene Therapy, Imperial College London, London, UK
    Eur Respir J 41:67-73. 2013
    ..Our data suggests that the use of OCs does not affect CF disease severity...
  16. doi Chest physiotherapy techniques in bronchiectasis
    Lizzie J Flude
    Physiotherapy Department, The Royal Brompton and Harefield NHS Foundation Trust, Royal Brompton Hospital, London, UK
    Clin Chest Med 33:351-61. 2012
    ..Physiotherapists aim to teach patients one of a variety of airway clearance techniques to regularly perform as part of their daily management...
  17. ncbi Patients' knowledge of cystic fibrosis: genetic determinism and implications for treatment
    Elizabeth Chapman
    Centre for Family Research, University of Cambridge, Cambridge, UK
    J Genet Couns 13:369-85. 2004
    ..Any important gaps in patient knowledge could usefully be discussed at transition from pediatric to adult care and issues relating to control and genetic determinism discussed with the patients individually...
  18. ncbi Cystic fibrosis pulmonary disease is not a contra-indication to live-related renal transplantation
    Damian J McKeon
    Nephrol Dial Transplant 20:664. 2005
  19. ncbi Addition of inhaled tobramycin to ciprofloxacin for acute exacerbations of Pseudomonas aeruginosa infection in adult bronchiectasis
    Diana Bilton
    Papworth Hospital, Adult CF Centre, Papworth Everard Cambridge, Cambridge CB38RE, UK
    Chest 130:1503-10. 2006
    ....
  20. ncbi Safety and efficacy of recombinant alpha(1)-antitrypsin therapy in cystic fibrosis
    S Lorraine Martin
    School of Pharmacy, Queen s University Belfast, Belfast, Northern Ireland, UK
    Pediatr Pulmonol 41:177-83. 2006
    ..This study demonstrated that nebulized rAAT is safe and well-tolerated, but has a limited effect on NE activity and other markers of inflammation...
  21. ncbi Osteoclastogenesis during infective exacerbations in patients with cystic fibrosis
    Elizabeth F Shead
    Department of Haematology, NHS Foundation Trust, Addenbrooke s Hospital, Cambridge, United Kingdom
    Am J Respir Crit Care Med 174:306-11. 2006
    ..Adults with cystic fibrosis (CF) are at increased risk of developing osteoporosis. During infective exacerbations, increased production of proinflammatory cytokines and markers of bone resorption have been reported...
  22. pmc Genetic determinants and epidemiology of cystic fibrosis-related diabetes: results from a British cohort of children and adults
    Amanda I Adler
    Addenbrooke s Hospital, Cambridge, UK
    Diabetes Care 31:1789-94. 2008
    ..In this study we documented the incidence of CFRD and evaluated the association between mutations responsible for cystic fibrosis and incident CFRD, while identifying potential risk factors...
  23. doi A randomized controlled trial of a new behavioral home-based nutrition education program, "Eat Well with CF," in adults with cystic fibrosis
    Helen Watson
    Department of Nutrition and Dietetics, Papworth Hospital, Papworth Everard, Cambridge, CB3 8RE, UK
    J Am Diet Assoc 108:847-52. 2008
    ..These need to be identified when subjects progress from pediatric to adult care, and programs such as "Eat Well with CF" are a useful adjunct for registered dietitians trying to manage this diverse but growing population...
  24. ncbi The relationship of clinical and inflammatory markers to outcome in stable patients with cystic fibrosis
    Damian G Downey
    Adult Cystic Fibrosis Centre, Belfast City Hospital and Queens University, Belfast, Northern Ireland
    Pediatr Pulmonol 42:216-20. 2007
    ..3 pM/mg creatinine (P = 0.001), in those patients who subsequently died compared to those that survived. These data suggest there is increased neutrophil degranulation in patients infected with Bc and these patients have a poor outcome...