J Wallace

Summary

Affiliation: Rowett Research Institute
Country: UK

Publications

  1. ncbi request reprint Effect of post-ovulation nutritional status in ewes on early conceptus survival and growth in vivo and luteotrophic protein secretion in vitro
    J M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    Reprod Fertil Dev 6:253-9. 1994
  2. ncbi request reprint Growth and metabolism of fetal and maternal muscles of adolescent sheep on adequate or high feed intake: possible role of protein kinase C-alpha in fetal muscle growth
    R M Palmer
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    Br J Nutr 79:351-7. 1998
  3. ncbi request reprint Influence of progesterone supplementation during the first third of pregnancy on fetal and placental growth in overnourished adolescent ewes
    J M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Reproduction 126:481-7. 2003
  4. ncbi request reprint Nutritionally mediated placental growth restriction in the growing adolescent: consequences for the fetus
    Jacqueline M Wallace
    The Rowett Research Institute, Bucksburn, Aberdeen, AB21 9SB United Kingdom
    Biol Reprod 71:1055-62. 2004
  5. pmc Placental glucose transport in growth-restricted pregnancies induced by overnourishing adolescent sheep
    Jacqueline M Wallace
    The Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    J Physiol 547:85-94. 2003
  6. ncbi request reprint Maternal growth hormone treatment from day 35 to 80 of gestation alters nutrient partitioning in favor of uteroplacental growth in the overnourished adolescent sheep
    Jacqueline M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Biol Reprod 70:1277-85. 2004
  7. ncbi request reprint Blood flows and nutrient uptakes in growth-restricted pregnancies induced by overnourishing adolescent sheep
    Jacqueline M Wallace
    The Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Am J Physiol Regul Integr Comp Physiol 282:R1027-36. 2002
  8. ncbi request reprint Nutrient partitioning during adolescent pregnancy
    J Wallace
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Reproduction 122:347-57. 2001
  9. pmc Investigating the causes of low birth weight in contrasting ovine paradigms
    J M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    J Physiol 565:19-26. 2005
  10. ncbi request reprint The effect of overnourishing singleton-bearing adult ewes on nutrient partitioning to the gravid uterus
    Jacqueline M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Br J Nutr 94:533-9. 2005

Detail Information

Publications31

  1. ncbi request reprint Effect of post-ovulation nutritional status in ewes on early conceptus survival and growth in vivo and luteotrophic protein secretion in vitro
    J M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    Reprod Fertil Dev 6:253-9. 1994
    ..abstract truncated at 250 words)..
  2. ncbi request reprint Growth and metabolism of fetal and maternal muscles of adolescent sheep on adequate or high feed intake: possible role of protein kinase C-alpha in fetal muscle growth
    R M Palmer
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    Br J Nutr 79:351-7. 1998
    ..This was the only isoform to demonstrate nutritionally related changes in it subcellular compartmentation suggesting that it may mediate some aspects of the change in fetal growth rate...
  3. ncbi request reprint Influence of progesterone supplementation during the first third of pregnancy on fetal and placental growth in overnourished adolescent ewes
    J M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Reproduction 126:481-7. 2003
    ..Thus, progesterone did not directly affect the growth of the fetal cotyledon but may have influenced placental vascularity, blood flow or nutrient transfer capacity or alternatively the development of the embryonic inner cell mass...
  4. ncbi request reprint Nutritionally mediated placental growth restriction in the growing adolescent: consequences for the fetus
    Jacqueline M Wallace
    The Rowett Research Institute, Bucksburn, Aberdeen, AB21 9SB United Kingdom
    Biol Reprod 71:1055-62. 2004
    ..In addition, the paradigm provides a robust model of placental growth restriction that replicates many of the key features of human intrauterine growth restriction per se...
  5. pmc Placental glucose transport in growth-restricted pregnancies induced by overnourishing adolescent sheep
    Jacqueline M Wallace
    The Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    J Physiol 547:85-94. 2003
    ..This confirms that the small size of the placenta per se is the major limitation to placental glucose transfer in the overnourished adolescent pregnant sheep...
  6. ncbi request reprint Maternal growth hormone treatment from day 35 to 80 of gestation alters nutrient partitioning in favor of uteroplacental growth in the overnourished adolescent sheep
    Jacqueline M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Biol Reprod 70:1277-85. 2004
    ..It remains to be established whether these effects are due wholly to alterations in maternal metabolism or if they also reflect an effect of bGH and/or the IGF system at the level of the uteroplacenta...
  7. ncbi request reprint Blood flows and nutrient uptakes in growth-restricted pregnancies induced by overnourishing adolescent sheep
    Jacqueline M Wallace
    The Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Am J Physiol Regul Integr Comp Physiol 282:R1027-36. 2002
    ..This indicates that increased fetal glucose clearance and/or insulin sensitivity may be operating as compensatory mechanisms to preserve normal fetal metabolism while fetal growth is sacrificed...
  8. ncbi request reprint Nutrient partitioning during adolescent pregnancy
    J Wallace
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Reproduction 122:347-57. 2001
    ....
  9. pmc Investigating the causes of low birth weight in contrasting ovine paradigms
    J M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    J Physiol 565:19-26. 2005
    ..Maintained utilization of these substrates, in a substrate-deficient environment, suggests increased sensitivities to metabolic signals, which may play a role in the development of metabolic diseases in later adult life...
  10. ncbi request reprint The effect of overnourishing singleton-bearing adult ewes on nutrient partitioning to the gravid uterus
    Jacqueline M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Br J Nutr 94:533-9. 2005
    ..Thus, adult sheep appear to be relatively insensitive to the oversupply of nutrients during pregnancy and have the ability to meet the nutrient requirements for normal conceptus growth in spite of their increased adiposity...
  11. ncbi request reprint Nutritional modulation of adolescent pregnancy outcome -- a review
    J M Wallace
    Development, Growth and Function Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB, UK
    Placenta 27:S61-8. 2006
    ..Thus, while the underlying mechanisms differ, maternal intake at both ends of the nutritional spectrum is a powerful determinant of fetal growth in pregnant adolescents...
  12. ncbi request reprint Late but not early gestational maternal growth hormone treatment increases fetal adiposity in overnourished adolescent sheep
    Jacqueline M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Biol Reprod 75:231-9. 2006
    ..Treatment during late pregnancy has a modest effect on fetal growth independent of placental size and a profound effect on fetal adiposity, which may have implications beyond the fetal period...
  13. ncbi request reprint Effect of diet composition on pregnancy outcome in overnourished rapidly growing adolescent sheep
    Jacqueline M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Br J Nutr 96:1060-8. 2006
    ..The data imply that it is high-energy intakes that are the primary cause of impaired placental development and adverse pregnancy outcome in rapidly growing adolescent sheep...
  14. ncbi request reprint Influence of placentally mediated fetal growth restriction on the onset of puberty in male and female lambs
    P Da Silva
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Reproduction 122:375-83. 2001
    ..01) but the timing of maximum peak concentrations was similar. Peak testosterone concentrations were lower (P < 0.05) in growth-restricted than in normal male lambs...
  15. doi request reprint Serial measurement of uterine blood flow from mid to late gestation in growth restricted pregnancies induced by overnourishing adolescent sheep dams
    J M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Placenta 29:718-24. 2008
    ..These data are commensurate with the reported decrease in placental angiogenic growth factor expression at mid gestation, and, indicate that attenuated UtBF is an early defect in this adolescent paradigm...
  16. ncbi request reprint Impact of maternal nutrition during pregnancy on pituitary gonadotrophin gene expression and ovarian development in growth-restricted and normally grown late gestation sheep fetuses
    P Da Silva
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Reproduction 123:769-77. 2002
    ..01). Thus, a high maternal nutrient intake during adolescent pregnancy had a negative influence on ovarian follicular development in fetuses as determined during late gestation...
  17. ncbi request reprint Circulating leptin during ovine pregnancy in relation to maternal nutrition, body composition and pregnancy outcome
    L Thomas
    Aberdeen Centre for Energy Regulation and Obesity, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    J Endocrinol 169:465-76. 2001
    ..The presence of leptin protein and leptin receptor gene expression in the placenta suggests that leptin could be involved in nutrient partitioning during placental and/or fetal development...
  18. ncbi request reprint Nutrient partitioning during pregnancy: adverse gestational outcome in overnourished adolescent dams
    J M Wallace
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Proc Nutr Soc 59:107-17. 2000
    ..Finally, the consequences of this form of inappropriate nutrient partitioning on the growth and development of the fetus and neonate are described with particular emphasis on the reproductive axis...
  19. ncbi request reprint Relationship between nutritionally-mediated placental growth restriction and fetal growth, body composition and endocrine status during late gestation in adolescent sheep
    J M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen, AB21 9SB, UK
    Placenta 21:100-8. 2000
    ..Thus, over-nourishing adolescent sheep is associated with a major restriction in placental growth which mediates a gradual slowing of fetal growth during the final third of pregnancy...
  20. ncbi request reprint Effect of maternal overnutrition during pregnancy on pituitary gonadotrophin gene expression and gonadal morphology in female and male foetal sheep at day 103 of gestation
    P Da Silva
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Placenta 24:248-57. 2003
    ..The latter effect was independent of gonadotrophin secretion.Crown..
  21. ncbi request reprint The effect of prenatal photoperiodic history on the postnatal endocrine status of female lambs
    R J Helliwell
    Rowett Research Institute, Aberdeen, UK
    Anim Reprod Sci 47:303-14. 1997
    ....
  22. ncbi request reprint Conceptus interferon in uterine flush, endometrial concentrations of oxytocin receptors and prostaglandin F2 alpha release in vitro after transfer of conceptuses to ewes induced to ovulate at 28 days postpartum
    J M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    J Reprod Fertil 103:299-305. 1995
    ..Similarly, basal and oxytocin-stimulated endometrial PGF2 alpha release during a 4 h incubation were higher (P < 0.01) in pregnant postpartum versus control recipients.(ABSTRACT TRUNCATED AT 250 WORDS)..
  23. ncbi request reprint Nutritional paradigms of ovine fetal growth restriction: implications for human pregnancy
    Justin S Luther
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    Hum Fertil (Camb) 8:179-87. 2005
    ..At the other end of the nutritional spectrum, undernourishing the adolescent sheep to gradually deplete nutrient reserves, results in fetal growth restriction which is independent of alterations in placental mass...
  24. doi request reprint Expression of energy balance regulatory genes in the developing ovine fetal hypothalamus at midgestation and the influence of hyperglycemia
    Clare L Adam
    Obesity and Metabolic Health Division, Rowett Research Institute, Bucksburn, Aberdeen, United Kingdom
    Am J Physiol Regul Integr Comp Physiol 294:R1895-900. 2008
    ..Such changes provide a potential mechanism for the prenatal origins of postnatal energy balance dysregulation and obesity...
  25. ncbi request reprint Sensitivity to metabolic signals in late-gestation growth-restricted fetuses from rapidly growing adolescent sheep
    Jacqueline M Wallace
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    Am J Physiol Endocrinol Metab 293:E1233-41. 2007
    ....
  26. pmc An immunohistochemical study of the localization and developmental expression of ghrelin and its functional receptor in the ovine placenta
    Joanne L Harrison
    School of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, WA, Australia
    Reprod Biol Endocrinol 5:25. 2007
    ..We tested the hypotheses that ghrelin and its functional receptor, GHSR-1a, are present in tissues of the ovine placenta, and that their expression is linked to the stage of development...
  27. ncbi request reprint The expression of ovine placental lactogen, StAR and progesterone-associated steroidogenic enzymes in placentae of overnourished growing adolescent ewes
    Richard G Lea
    School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Sutton Bonington LE12 5RD, UK
    Reproduction 133:785-96. 2007
    ..Restricted placental growth and reduced biosynthesis may account for reduced progesterone in day 130 H+IUGR ewes...
  28. ncbi request reprint Influence of maternal nutrition on messenger RNA expression of placental angiogenic factors and their receptors at midgestation in adolescent sheep
    Dale A Redmer
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Biol Reprod 72:1004-9. 2005
    ..This may impact placental vascularity and explain why uteroplacental mass, blood flow, and nutrient uptake are compromised in late pregnancy, resulting in low-birth-weight offspring...
  29. ncbi request reprint Overnourishing pregnant adolescent ewes preserves perirenal fat deposition in their growth-restricted fetuses
    Masatoshi Matsuzaki
    National Agricultural Research Center for Kyushu Okinawa Region, Nishigoshi machi, Kumamoto 861 1192, Japan
    Reprod Fertil Dev 18:357-64. 2006
    ..01). Thus, overnourishing pregnant adolescent sheep preserves fat deposition in their growth-restricted fetuses, which may have implications for neonatal thermogenesis and for programming of postnatal adiposity...
  30. ncbi request reprint Developmental indices of nutritionally induced placental growth restriction in the adolescent sheep
    Richard G Lea
    Ovine Pregnancy Group, Rowett Research Institute, Bucksburn, Aberdeen, Scotland
    Pediatr Res 57:599-604. 2005
    ..These observations indicate that reduced placental size at term may be due to reduced placental cell proliferation and possibly increased apoptosis occurring much earlier in gestation...
  31. pmc Evidence for altered placental blood flow and vascularity in compromised pregnancies
    Lawrence P Reynolds
    Center for Nutrition and Pregnancy, and Department of Animal and Range Sciences, North Dakota State University, Fargo ND 58105 5727, USA
    J Physiol 572:51-8. 2006
    ..Placental blood flow and vascular development are thus potential therapeutic targets in compromised pregnancies...