Klaus W J Wahle

Summary

Affiliation: Rowett Research Institute
Country: UK

Publications

  1. ncbi request reprint Polyunsaturated fatty acids and gene expression in mammalian systems
    Klaus W J Wahle
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Proc Nutr Soc 62:349-60. 2003
  2. ncbi request reprint Conjugated linoleic acid inhibits proliferation and modulates protein kinase C isoforms in human prostate cancer cells
    Hyun Ju Song
    The Rowett Research Institute, Bucksburn, Aberdeen, Scotland, UK
    Nutr Cancer 49:100-8. 2004
  3. ncbi request reprint Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid
    Alan A Sneddon
    Lipid and Redox Regulation Group, Vascular Health Programme, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Biochim Biophys Acta 1761:793-801. 2006
  4. doi request reprint Effect of a conjugated linoleic acid and omega-3 fatty acid mixture on body composition and adiponectin
    Alan A Sneddon
    Vascular Health Division, Rowett Research Institute, Aberdeen, UK
    Obesity (Silver Spring) 16:1019-24. 2008
  5. ncbi request reprint Regulation of selenoprotein GPx4 expression and activity in human endothelial cells by fatty acids, cytokines and antioxidants
    Alan A Sneddon
    Lipid and Redox Regulation Group, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Atherosclerosis 171:57-65. 2003
  6. ncbi request reprint Cytoprotective effects of phenolic antioxidants and essential fatty acids in human blood monocyte and neuroblastoma cell lines: surrogates for neurological damage in vivo
    Julie Young
    School of Pharmacy, The Robert Gordon University, Schoolhill, Aberdeen, UK
    Prostaglandins Leukot Essent Fatty Acids 78:45-59. 2008
  7. ncbi request reprint Potentiation of the anti-tumour effect of docetaxel by conjugated linoleic acids (CLAs) in breast cancer cells in vitro
    Alemu Fite
    Section of Surgical Oncology, Department of Surgery, University of Aberdeen, Medical School, Foresterhill, Aberdeen, Aberdeen, Scotland, UK
    Prostaglandins Leukot Essent Fatty Acids 77:87-96. 2007
  8. ncbi request reprint Age- and dose-dependent effects of an eicosapentaenoic acid-rich oil on cardiovascular risk factors in healthy male subjects
    Roberta Cazzola
    Department of Preclinical Sciences LITA Vialba, University of Milan, 74 Via G B Grassi, Milan 20157, Italy
    Atherosclerosis 193:159-67. 2007
  9. ncbi request reprint Induction of apoptosis and inhibition of NF-kappaB activation in human prostate cancer cells by the cis-9, trans-11 but not the trans-10, cis-12 isomer of conjugated linoleic acid
    Hyun Ju Song
    The Robert Gordon University, School of Life Sciences, St Andrews Street, Aberdeen, United Kingdom
    Prostate 66:839-46. 2006
  10. ncbi request reprint Atherosclerosis: cell biology and lipoproteins
    Marie Goua
    Curr Opin Lipidol 16:389-91. 2005

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Polyunsaturated fatty acids and gene expression in mammalian systems
    Klaus W J Wahle
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Proc Nutr Soc 62:349-60. 2003
    ..The latter will at least stimulate controversy in this exciting area of lipid research...
  2. ncbi request reprint Conjugated linoleic acid inhibits proliferation and modulates protein kinase C isoforms in human prostate cancer cells
    Hyun Ju Song
    The Rowett Research Institute, Bucksburn, Aberdeen, Scotland, UK
    Nutr Cancer 49:100-8. 2004
    ..Increased PKC-delta and decreased PKC-iota membrane abundance was consistent with CLAs eliciting increased apoptosis and, in part, with their antitumor effects...
  3. ncbi request reprint Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid
    Alan A Sneddon
    Lipid and Redox Regulation Group, Vascular Health Programme, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Biochim Biophys Acta 1761:793-801. 2006
    ....
  4. doi request reprint Effect of a conjugated linoleic acid and omega-3 fatty acid mixture on body composition and adiponectin
    Alan A Sneddon
    Vascular Health Division, Rowett Research Institute, Aberdeen, UK
    Obesity (Silver Spring) 16:1019-24. 2008
    ....
  5. ncbi request reprint Regulation of selenoprotein GPx4 expression and activity in human endothelial cells by fatty acids, cytokines and antioxidants
    Alan A Sneddon
    Lipid and Redox Regulation Group, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Atherosclerosis 171:57-65. 2003
    ..These results indicate that lipids, cytokines and antioxidants modulate GPx4 in a complex manner that in the presence of adequate selenium, may favour protection against potentially proatherogenic processes...
  6. ncbi request reprint Cytoprotective effects of phenolic antioxidants and essential fatty acids in human blood monocyte and neuroblastoma cell lines: surrogates for neurological damage in vivo
    Julie Young
    School of Pharmacy, The Robert Gordon University, Schoolhill, Aberdeen, UK
    Prostaglandins Leukot Essent Fatty Acids 78:45-59. 2008
    ..Robust in vitro systems are desirable, enabling a mechanistic investigation of the molecular mechanisms underpinning such effects and identification of further potentially efficacious nutraceuticals...
  7. ncbi request reprint Potentiation of the anti-tumour effect of docetaxel by conjugated linoleic acids (CLAs) in breast cancer cells in vitro
    Alemu Fite
    Section of Surgical Oncology, Department of Surgery, University of Aberdeen, Medical School, Foresterhill, Aberdeen, Aberdeen, Scotland, UK
    Prostaglandins Leukot Essent Fatty Acids 77:87-96. 2007
    ..Results show that CLA isomers augment anti-tumour effects of docetaxel in breast cancer cells and suggest possible dual treatment regimens...
  8. ncbi request reprint Age- and dose-dependent effects of an eicosapentaenoic acid-rich oil on cardiovascular risk factors in healthy male subjects
    Roberta Cazzola
    Department of Preclinical Sciences LITA Vialba, University of Milan, 74 Via G B Grassi, Milan 20157, Italy
    Atherosclerosis 193:159-67. 2007
    ..Young males are unlikely to suffer adverse consequences from high EPA intake, whereas older males may have an increased risk of lipoprotein peroxidation...
  9. ncbi request reprint Induction of apoptosis and inhibition of NF-kappaB activation in human prostate cancer cells by the cis-9, trans-11 but not the trans-10, cis-12 isomer of conjugated linoleic acid
    Hyun Ju Song
    The Robert Gordon University, School of Life Sciences, St Andrews Street, Aberdeen, United Kingdom
    Prostate 66:839-46. 2006
    ..The present study investigated the effects of CLAs (cis-9, trans-11, and trans-10, cis-12 isomers and a 50:50 mixture) on apoptosis and NF-kappaB activation in LNCaP cells...
  10. ncbi request reprint Atherosclerosis: cell biology and lipoproteins
    Marie Goua
    Curr Opin Lipidol 16:389-91. 2005
  11. ncbi request reprint Conjugated linoleic acids: are they beneficial or detrimental to health?
    Klaus W J Wahle
    School of Life Sciences, The Robert Gordon University, Aberdeen AB 25 1GH, UK
    Prog Lipid Res 43:553-87. 2004
    ....
  12. ncbi request reprint Atherosclerosis: cell biology and lipoproteins
    Klaus W J Wahle
    Curr Opin Lipidol 15:491-3. 2004
  13. ncbi request reprint Conjugated linoleic acids (CLAs) decrease prostate cancer cell proliferation: different molecular mechanisms for cis-9, trans-11 and trans-10, cis-12 isomers
    Julio J Ochoa
    Institute of Nutrition and Food Technology, Department of Physiology, University of Granada, C Ramon y Cajal 4, 18071, Granada, Spain
    Carcinogenesis 25:1185-91. 2004
    ..Trans-10, cis-12 seems to work preferentially through modulation of apoptosis and cell cycle control, while c9,t11 CLA isomer affects arachidonic acid metabolism...
  14. ncbi request reprint Olive oil phenolics: effects on DNA oxidation and redox enzyme mRNA in prostate cells
    Jose L Quiles
    Institute of Nutrition and Food Technology, Department of Physiology, University of Granada, Granada, Spain
    Br J Nutr 88:225-34; discussion 223-4. 2002
    ..Tyrosol appeared to exhibit pro-oxidant effects (only at high concentrations) and caffeic acid was neutral. Both number and position of hydroxyl groups appear to play a role in the cellular effects of hydroxytyrosol...