Wendy R Russell

Summary

Affiliation: Rowett Research Institute
Country: UK

Publications

  1. ncbi request reprint Extent of incorporation of hydroxycinnamaldehydes into lignin in cinnamyl alcohol dehydrogenase-downregulated plants
    W R Russell
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    J Biotechnol 79:73-85. 2000
  2. ncbi request reprint Radical formation and coupling of hydroxycinnamic acids containing 1,2-dihydroxy substituents
    Wendy R Russell
    Rowett Research Institute, Greenburn Road, Bucksburn, AB21 9SB Aberdeen, UK
    Bioorg Chem 31:206-15. 2003
  3. ncbi request reprint Structural modification of phenylpropanoid-derived compounds and the effects on their participation in redox processes
    Wendy R Russell
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Bioorg Med Chem 13:2537-46. 2005
  4. doi request reprint Anti-inflammatory implications of the microbial transformation of dietary phenolic compounds
    Wendy R Russell
    Molecular Nutrition Group, Rowett Research Institute, Aberdeen, United Kingdom
    Nutr Cancer 60:636-42. 2008
  5. ncbi request reprint Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications
    Wendy R Russell
    Molecular Nutrition Group, Rowett Research Institute, Aberdeen, UK
    Mol Nutr Food Res 51:726-31. 2007
  6. doi request reprint Selective bio-availability of phenolic acids from Scottish strawberries
    Wendy R Russell
    Molecular Nutrition Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK
    Mol Nutr Food Res 53:S85-91. 2009
  7. ncbi request reprint Salicylate modulates oxidative stress in the rat colon: a proteomic approach
    Janice E Drew
    Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB Scotland, UK
    Biochem Pharmacol 72:204-16. 2006
  8. ncbi request reprint Salicylic acid modulates oxidative stress and glutathione peroxidase activity in the rat colon
    Janice E Drew
    Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
    Biochem Pharmacol 70:888-93. 2005
  9. doi request reprint Major phenylpropanoid-derived metabolites in the human gut can arise from microbial fermentation of protein
    Wendy R Russell
    Molecular Nutrition Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK
    Mol Nutr Food Res 57:523-35. 2013
  10. ncbi request reprint EPR investigation into the effects of substrate structure on peroxidase-catalyzed phenylpropanoid oxidation
    Wendy R Russell
    Molecular Nutrition Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, United Kingdom
    Biomacromolecules 7:268-73. 2006

Detail Information

Publications19

  1. ncbi request reprint Extent of incorporation of hydroxycinnamaldehydes into lignin in cinnamyl alcohol dehydrogenase-downregulated plants
    W R Russell
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    J Biotechnol 79:73-85. 2000
    ....
  2. ncbi request reprint Radical formation and coupling of hydroxycinnamic acids containing 1,2-dihydroxy substituents
    Wendy R Russell
    Rowett Research Institute, Greenburn Road, Bucksburn, AB21 9SB Aberdeen, UK
    Bioorg Chem 31:206-15. 2003
    ..In contrast, when methoxylated at C3, as in 4,5-dihydroxy-3-methoxycinnamic acid, radical coupling proceeds with the major product resulting from 8-O-3 radical coupling and formation of a substituted 2,3-dihydro-1,4-dioxin ring...
  3. ncbi request reprint Structural modification of phenylpropanoid-derived compounds and the effects on their participation in redox processes
    Wendy R Russell
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Bioorg Med Chem 13:2537-46. 2005
    ..The importance of quinone formation in compounds containing more than one hydroxyl substituent was highlighted, as this was found to have a significant effect on stabilisation and therefore, their participation in redox processes...
  4. doi request reprint Anti-inflammatory implications of the microbial transformation of dietary phenolic compounds
    Wendy R Russell
    Molecular Nutrition Group, Rowett Research Institute, Aberdeen, United Kingdom
    Nutr Cancer 60:636-42. 2008
    ..This suggests that the microbial transformation of dietary compounds will have important inflammatory implications in the chemoprevention of colon cancer...
  5. ncbi request reprint Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications
    Wendy R Russell
    Molecular Nutrition Group, Rowett Research Institute, Aberdeen, UK
    Mol Nutr Food Res 51:726-31. 2007
    ..Studies addressing a wide-range of well-characterised human volunteers will be required before such health claims can be fully established...
  6. doi request reprint Selective bio-availability of phenolic acids from Scottish strawberries
    Wendy R Russell
    Molecular Nutrition Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK
    Mol Nutr Food Res 53:S85-91. 2009
    ..If selective absorption of phenolic acids is observed with consumption of other plant-based foods, this is likely to have implications for the bioactive role of these compounds in chronic disease prevention...
  7. ncbi request reprint Salicylate modulates oxidative stress in the rat colon: a proteomic approach
    Janice E Drew
    Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB Scotland, UK
    Biochem Pharmacol 72:204-16. 2006
    ....
  8. ncbi request reprint Salicylic acid modulates oxidative stress and glutathione peroxidase activity in the rat colon
    Janice E Drew
    Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
    Biochem Pharmacol 70:888-93. 2005
    ..The ability of salicylic acid to modulate antioxidant enzymes in colon tissue may be an important mechanism in inhibiting colon cancer development...
  9. doi request reprint Major phenylpropanoid-derived metabolites in the human gut can arise from microbial fermentation of protein
    Wendy R Russell
    Molecular Nutrition Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK
    Mol Nutr Food Res 57:523-35. 2013
    ..Although they have the potential to be derived from diets rich in plant-based foods, evidence suggests that these compounds can be derived from the microbial fermentation of aromatic amino acids (AAAs) in the colon...
  10. ncbi request reprint EPR investigation into the effects of substrate structure on peroxidase-catalyzed phenylpropanoid oxidation
    Wendy R Russell
    Molecular Nutrition Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, United Kingdom
    Biomacromolecules 7:268-73. 2006
    ..The results indicate that the polymer grows primarily as a result of the reactivity of the monomers and that polymerization to high molecular weight may be restricted to methoxylated species...
  11. doi request reprint Inhibition of 15-lipoxygenase-catalysed oxygenation of arachidonic acid by substituted benzoic acids
    Wendy R Russell
    Molecular Nutrition Group, Rowett Research Institute, Aberdeen, AB21 9SB, Scotland, UK
    Bioorg Med Chem 16:4589-93. 2008
    ..No correlation was observed with the ability to act as reductants, supporting the hypothesis that their mode of inhibition may not be by a direct redox effect on the non-haem iron...
  12. doi request reprint High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health
    Wendy R Russell
    Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom
    Am J Clin Nutr 93:1062-72. 2011
    ..However, the effect of such diets on microbiota-derived metabolites that influence colonic health has not been established...
  13. ncbi request reprint Inhibition of cytokine-induced prostanoid biogenesis by phytochemicals in human colonic fibroblasts
    Wendy R Russell
    Gut Health Division, Molecular Nutrition Group, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
    Biochim Biophys Acta 1762:124-30. 2006
    ..Common structural features of the inhibitors were the presence of 4-hydroxyl and 3-methoxyl substituents on the aromatic ring and/or the presence of a three-carbon side-chain on C1...
  14. doi request reprint Colonic bacterial metabolites and human health
    Wendy R Russell
    Rowett Institute of Nutrition and Health, University of Aberdeen, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Curr Opin Microbiol 16:246-54. 2013
    ..In addition, the role of the gut microbiota in choline deficiency in non-alcoholic fatty liver disease (NAFLD) and insulin resistance is receiving increased attention. ..
  15. doi request reprint The gut microbial metabolome: modulation of cancer risk in obese individuals
    Wendy R Russell
    Lifelong Health Division, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB21 9SB, UK
    Proc Nutr Soc 72:178-88. 2013
    ..It is clear that only if the link between microbial diversity and metabolic functionality is firmly established, will the mechanism by which gut microbiota maintains health or contributes to disease development be elucidated...
  16. ncbi request reprint Copper-homocysteine complexes and potential physiological actions
    Margarita D Apostolova
    Department of Cellular Integrity, Rowett Research Institute, Aberdeen AB219SB, UK
    J Inorg Biochem 95:321-33. 2003
    ..Together, these observations suggest that Cu-hCys complexes actively participate in the biochemical responses of endothelial cells that are involved in the aethiopathogenesis of atherosclerosis...
  17. ncbi request reprint A proteomics approach to identify changes in protein profiles in pre-cancerous colon
    Janice E Drew
    Cellular Integrity Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB Scotland, UK
    Biochem Biophys Res Commun 330:81-7. 2005
    ..These changes may have a potential role in the identification of pre-pathological features preceding colon tumorigenesis...
  18. doi request reprint Mechanism of conjugated linoleic acid and vaccenic acid formation in human faecal suspensions and pure cultures of intestinal bacteria
    Freda M McIntosh
    Gut Health Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Microbiology 155:285-94. 2009
    ..A hydrogen-abstraction enzymic mechanism is proposed that may explain the role of a 10-OH-18 : 1 intermediate in 9,11-CLA formation in pure and mixed cultures...
  19. ncbi request reprint Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifolium
    Lutfun Nahar
    School of Life Sciences, The Robert Gordon University, Aberdeen AB25 1HG, Scotland, UK
    Acta Pharm 55:187-93. 2005
    ..In the DPPH assay for antioxidant activity, the IC(50) values of 1 and 2 were 1.50 x 10(-3) and 2.55 x 10(-3) mg mL(-1), respectively, compared to 2.88 x 10(-5) mg mL(-1) of quercetin, a natural antioxidant...