Research Topics
| Wendy R RussellSummaryAffiliation: Rowett Research Institute Country: UK Publications
| Collaborators |
Detail Information
Publications
Extent of incorporation of hydroxycinnamaldehydes into lignin in cinnamyl alcohol dehydrogenase-downregulated plantsW R Russell
Rowett Research Institute, Bucksburn, Aberdeen, UK
J Biotechnol 79:73-85. 2000....- Radical formation and coupling of hydroxycinnamic acids containing 1,2-dihydroxy substituentsWendy R Russell
Rowett Research Institute, Greenburn Road, Bucksburn, AB21 9SB Aberdeen, UK
Bioorg Chem 31:206-15. 2003..In contrast, when methoxylated at C3, as in 4,5-dihydroxy-3-methoxycinnamic acid, radical coupling proceeds with the major product resulting from 8-O-3 radical coupling and formation of a substituted 2,3-dihydro-1,4-dioxin ring... - Structural modification of phenylpropanoid-derived compounds and the effects on their participation in redox processesWendy R Russell
Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
Bioorg Med Chem 13:2537-46. 2005..The importance of quinone formation in compounds containing more than one hydroxyl substituent was highlighted, as this was found to have a significant effect on stabilisation and therefore, their participation in redox processes... 
Anti-inflammatory implications of the microbial transformation of dietary phenolic compoundsWendy R Russell
Molecular Nutrition Group, Rowett Research Institute, Aberdeen, United Kingdom
Nutr Cancer 60:636-42. 2008..This suggests that the microbial transformation of dietary compounds will have important inflammatory implications in the chemoprevention of colon cancer...- Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implicationsWendy R Russell
Molecular Nutrition Group, Rowett Research Institute, Aberdeen, UK
Mol Nutr Food Res 51:726-31. 2007..Studies addressing a wide-range of well-characterised human volunteers will be required before such health claims can be fully established... - Selective bio-availability of phenolic acids from Scottish strawberriesWendy R Russell
Molecular Nutrition Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK
Mol Nutr Food Res 53:S85-91. 2009..If selective absorption of phenolic acids is observed with consumption of other plant-based foods, this is likely to have implications for the bioactive role of these compounds in chronic disease prevention... - Salicylate modulates oxidative stress in the rat colon: a proteomic approachJanice E Drew
Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB Scotland, UK
Biochem Pharmacol 72:204-16. 2006.... - Salicylic acid modulates oxidative stress and glutathione peroxidase activity in the rat colonJanice E Drew
Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
Biochem Pharmacol 70:888-93. 2005..The ability of salicylic acid to modulate antioxidant enzymes in colon tissue may be an important mechanism in inhibiting colon cancer development... - EPR investigation into the effects of substrate structure on peroxidase-catalyzed phenylpropanoid oxidationWendy R Russell
Molecular Nutrition Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, United Kingdom
Biomacromolecules 7:268-73. 2006..The results indicate that the polymer grows primarily as a result of the reactivity of the monomers and that polymerization to high molecular weight may be restricted to methoxylated species... - Inhibition of 15-lipoxygenase-catalysed oxygenation of arachidonic acid by substituted benzoic acidsWendy R Russell
Molecular Nutrition Group, Rowett Research Institute, Aberdeen, AB21 9SB, Scotland, UK
Bioorg Med Chem 16:4589-93. 2008..No correlation was observed with the ability to act as reductants, supporting the hypothesis that their mode of inhibition may not be by a direct redox effect on the non-haem iron... - High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic healthWendy R Russell
Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom
Am J Clin Nutr 93:1062-72. 2011..However, the effect of such diets on microbiota-derived metabolites that influence colonic health has not been established... - Inhibition of cytokine-induced prostanoid biogenesis by phytochemicals in human colonic fibroblastsWendy R Russell
Gut Health Division, Molecular Nutrition Group, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
Biochim Biophys Acta 1762:124-30. 2006..Common structural features of the inhibitors were the presence of 4-hydroxyl and 3-methoxyl substituents on the aromatic ring and/or the presence of a three-carbon side-chain on C1... - Major phenylpropanoid-derived metabolites in the human gut can arise from microbial fermentation of proteinWendy R Russell
Molecular Nutrition Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK
Mol Nutr Food Res 57:523-35. 2013..Although they have the potential to be derived from diets rich in plant-based foods, evidence suggests that these compounds can be derived from the microbial fermentation of aromatic amino acids (AAAs) in the colon... - Copper-homocysteine complexes and potential physiological actionsMargarita D Apostolova
Department of Cellular Integrity, Rowett Research Institute, Aberdeen AB219SB, UK
J Inorg Biochem 95:321-33. 2003..Together, these observations suggest that Cu-hCys complexes actively participate in the biochemical responses of endothelial cells that are involved in the aethiopathogenesis of atherosclerosis... - A proteomics approach to identify changes in protein profiles in pre-cancerous colonJanice E Drew
Cellular Integrity Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB Scotland, UK
Biochem Biophys Res Commun 330:81-7. 2005..These changes may have a potential role in the identification of pre-pathological features preceding colon tumorigenesis... - The gut microbial metabolome: modulation of cancer risk in obese individualsWendy R Russell
Lifelong Health Division, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB21 9SB, UK
Proc Nutr Soc 72:178-88. 2013..It is clear that only if the link between microbial diversity and metabolic functionality is firmly established, will the mechanism by which gut microbiota maintains health or contributes to disease development be elucidated... - Mechanism of conjugated linoleic acid and vaccenic acid formation in human faecal suspensions and pure cultures of intestinal bacteriaFreda M McIntosh
Gut Health Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
Microbiology 155:285-94. 2009..A hydrogen-abstraction enzymic mechanism is proposed that may explain the role of a 10-OH-18 : 1 intermediate in 9,11-CLA formation in pure and mixed cultures... - Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifoliumLutfun Nahar
School of Life Sciences, The Robert Gordon University, Aberdeen AB25 1HG, Scotland, UK
Acta Pharm 55:187-93. 2005..In the DPPH assay for antioxidant activity, the IC(50) values of 1 and 2 were 1.50 x 10(-3) and 2.55 x 10(-3) mg mL(-1), respectively, compared to 2.88 x 10(-5) mg mL(-1) of quercetin, a natural antioxidant...