D Kelly

Summary

Affiliation: Rowett Research Institute
Country: UK

Publications

  1. ncbi Escherichia coli K88 receptor expression in intestine of disease-susceptible weaned pigs
    M D Jeyasingham
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    Vet Microbiol 68:219-34. 1999
  2. ncbi Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA
    Denise Kelly
    Gut Immunology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
    Nat Immunol 5:104-12. 2004
  3. ncbi Early nutrition and the development of immune function in the neonate
    D Kelly
    Department of Intestinal Cell Biology and Immunology, Rowett Research Institute, Bucksburn, Aberdeen, UK
    Proc Nutr Soc 59:177-85. 2000
  4. ncbi Bacterial modulation of mucosal innate immunity
    Denise Kelly
    Gut Immunology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Mol Immunol 42:895-901. 2005
  5. ncbi Importance of microbial colonization of the gut in early life to the development of immunity
    Denise Kelly
    Rowett Research Institute, Aberdeen, Scotland
    Mutat Res 622:58-69. 2007
  6. ncbi Inflammatory bowel disease, gut bacteria and probiotic therapy
    Caroline Reiff
    Department of Gut Immunology, Rowett Institute of Nutrition and Health, Greenburn Road, Bucksburn, AB21 9SB Aberdeen, UK
    Int J Med Microbiol 300:25-33. 2010
  7. ncbi Novel immunostimulatory agent based on CpG oligodeoxynucleotide linked to the nontoxic B subunit of cholera toxin
    Jenni Adamsson
    Department of Medical Microbiology and Immunology, Göteborg University Vaccine Research Institute, Goteborg University, Goteborg, Sweden
    J Immunol 176:4902-13. 2006
  8. ncbi Flagellin suppresses epithelial apoptosis and limits disease during enteric infection
    Matam Vijay-Kumar
    Department of Pathology and Laboratory Medicine, Epithelial Pathobiology Unit, Emory University School of Medicine, Atlanta, GA 30322, USA
    Am J Pathol 169:1686-700. 2006

Collaborators

  • Andrew Neish
  • M D Jeyasingham
  • Caroline Reiff
  • Matam Vijay-Kumar
  • Jenni Adamsson
  • Timothy P King
  • Huixia Wu
  • George Grant
  • Ali M Harandi
  • Annika Lundqvist
  • Marianne Lindblad
  • Rheinallt Jones
  • Andrew T Gewirtz
  • Jan Holmgren
  • Brian Babbin

Detail Information

Publications8

  1. ncbi Escherichia coli K88 receptor expression in intestine of disease-susceptible weaned pigs
    M D Jeyasingham
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    Vet Microbiol 68:219-34. 1999
    ..These results suggest that genetic differences in the glycosyl moieties of the receptor complex provide the basis for disease susceptibility to K88-positive E. coli...
  2. ncbi Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA
    Denise Kelly
    Gut Immunology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
    Nat Immunol 5:104-12. 2004
    ..thetaiotaomicron. This PPAR-gamma-dependent anti-inflammatory mechanism defines new cellular targets for therapeutic drug design and interventions for the treatment of chronic inflammation...
  3. ncbi Early nutrition and the development of immune function in the neonate
    D Kelly
    Department of Intestinal Cell Biology and Immunology, Rowett Research Institute, Bucksburn, Aberdeen, UK
    Proc Nutr Soc 59:177-85. 2000
    ..One factor that has been proposed to contribute to the increase in the incidence of immune-based disorders, e.g. atopic diseases in Western countries, is thought to be the increased prevalence of formula-feeding...
  4. ncbi Bacterial modulation of mucosal innate immunity
    Denise Kelly
    Gut Immunology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Mol Immunol 42:895-901. 2005
    ..Hence, the possibility exists that bacterially derived effector molecules, with defined modes of action, may have clinical relevance and application...
  5. ncbi Importance of microbial colonization of the gut in early life to the development of immunity
    Denise Kelly
    Rowett Research Institute, Aberdeen, Scotland
    Mutat Res 622:58-69. 2007
    ..However, much remains to be elucidated about how commensal bacteria influence the function of cells of both the innate and adaptive immune systems in health and disease...
  6. ncbi Inflammatory bowel disease, gut bacteria and probiotic therapy
    Caroline Reiff
    Department of Gut Immunology, Rowett Institute of Nutrition and Health, Greenburn Road, Bucksburn, AB21 9SB Aberdeen, UK
    Int J Med Microbiol 300:25-33. 2010
    ..Bacterial-host events, including interactions with pattern recognition receptors (PRRs) expressed on epithelial cells and dendritic cells (DCs) and the resultant impact on immune responses at mucosal surfaces will be discussed...
  7. ncbi Novel immunostimulatory agent based on CpG oligodeoxynucleotide linked to the nontoxic B subunit of cholera toxin
    Jenni Adamsson
    Department of Medical Microbiology and Immunology, Göteborg University Vaccine Research Institute, Goteborg University, Goteborg, Sweden
    J Immunol 176:4902-13. 2006
    ..To our knowledge, CTB is the first nontoxic derivative of microbial toxins discovered that when chemically linked to CpG remarkably augments the CpG-mediated immune responses...
  8. ncbi Flagellin suppresses epithelial apoptosis and limits disease during enteric infection
    Matam Vijay-Kumar
    Department of Pathology and Laboratory Medicine, Epithelial Pathobiology Unit, Emory University School of Medicine, Atlanta, GA 30322, USA
    Am J Pathol 169:1686-700. 2006
    ..This notion is consistent with the emerging paradigm that specific TLR ligands may have a fundamental cytoprotective effect during inflammatory stress...