S H Duncan

Summary

Affiliation: Rowett Research Institute
Country: UK

Publications

  1. ncbi request reprint Effects of esculin and esculetin on the survival of Escherichia coli O157 in human faecal slurries, continuous-flow simulations of the rumen and colon and in calves
    Sylvia H Duncan
    Gut Microbiology and Immunology Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Br J Nutr 91:749-55. 2004
  2. ncbi request reprint Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov
    Sylvia H Duncan
    Division of Gut Microbiology and Immunology, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen A821 9SB, UK
    Int J Syst Evol Microbiol 52:2141-6. 2002
  3. ncbi request reprint Cultivable bacterial diversity from the human colon
    S H Duncan
    Rowett Research Institute, Microbial Ecology Group, Aberdeen, UK
    Lett Appl Microbiol 44:343-50. 2007
  4. ncbi request reprint Roseburia intestinalis sp. nov., a novel saccharolytic, butyrate-producing bacterium from human faeces
    Sylvia H Duncan
    Gut Microbiology and Immunology Division, Rowett Research Institute, Bucksburn, Aberdeen, UK
    Int J Syst Evol Microbiol 52:1615-20. 2002
  5. pmc Acetate utilization and butyryl coenzyme A (CoA):acetate-CoA transferase in butyrate-producing bacteria from the human large intestine
    Sylvia H Duncan
    Division of Gut Microbiology and Immunology, Rowett Research Institute Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 68:5186-90. 2002
  6. doi request reprint Proposal of a neotype strain (A1-86) for Eubacterium rectale. Request for an opinion
    Sylvia H Duncan
    Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, UK
    Int J Syst Evol Microbiol 58:1735-6. 2008
  7. ncbi request reprint Characteristics of sheep-rumen isolates of Pseudomonas aeruginosa inhibitory to the growth of Escherichia coli O157
    S H Duncan
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    FEMS Microbiol Lett 180:305-10. 1999
  8. ncbi request reprint Inhibitory activity of gut bacteria against Escherichia coli O157 mediated by dietary plant metabolites
    S H Duncan
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    FEMS Microbiol Lett 164:283-8. 1998
  9. ncbi request reprint Understanding the effects of diet on bacterial metabolism in the large intestine
    P Louis
    Microbial Ecology Group, Rowett Research Institute, Aberdeen, UK
    J Appl Microbiol 102:1197-208. 2007
  10. ncbi request reprint Dietary effects on the microbiological safety of food
    E C McWilliam Leitch
    Gut Microbiology and Immunology Division, Rowett Research Institute, Bucksburn, Aberdeen, UK
    Proc Nutr Soc 60:247-55. 2001

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Effects of esculin and esculetin on the survival of Escherichia coli O157 in human faecal slurries, continuous-flow simulations of the rumen and colon and in calves
    Sylvia H Duncan
    Gut Microbiology and Immunology Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Br J Nutr 91:749-55. 2004
    ..Coumarin compounds that occur naturally in dietary plants or when supplemented in the diet probably inhibit the survival of E. coli O157 in the gut...
  2. ncbi request reprint Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov
    Sylvia H Duncan
    Division of Gut Microbiology and Immunology, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen A821 9SB, UK
    Int J Syst Evol Microbiol 52:2141-6. 2002
    ..nov., comb. nov. ATCC 27768(T) (= NCIMB 13872(T)) (formerly Fusobacterium prausnitzii) as the type species together with ATCC 27766 and the newly isolated strains A2-165 and L2-6...
  3. ncbi request reprint Cultivable bacterial diversity from the human colon
    S H Duncan
    Rowett Research Institute, Microbial Ecology Group, Aberdeen, UK
    Lett Appl Microbiol 44:343-50. 2007
    ..Despite this many new species are being isolated and described that occupy distinct niches in the colonic microbial community. This review focuses on these under-studied yet important gut anaerobes...
  4. ncbi request reprint Roseburia intestinalis sp. nov., a novel saccharolytic, butyrate-producing bacterium from human faeces
    Sylvia H Duncan
    Gut Microbiology and Immunology Division, Rowett Research Institute, Bucksburn, Aberdeen, UK
    Int J Syst Evol Microbiol 52:1615-20. 2002
    ..It is proposed that a novel species, Roseburia intestinalis sp. nov., be created, with strain L1-82T (= DSM 14610T = NCIMB 13810T) as the type strain...
  5. pmc Acetate utilization and butyryl coenzyme A (CoA):acetate-CoA transferase in butyrate-producing bacteria from the human large intestine
    Sylvia H Duncan
    Division of Gut Microbiology and Immunology, Rowett Research Institute Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 68:5186-90. 2002
    ..These results demonstrate that different functionally distinct groups of butyrate-producing bacteria are present in the human large intestine...
  6. doi request reprint Proposal of a neotype strain (A1-86) for Eubacterium rectale. Request for an opinion
    Sylvia H Duncan
    Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, UK
    Int J Syst Evol Microbiol 58:1735-6. 2008
    ..It is therefore proposed that strain A1-86 (=DSM 17629=NCIMB 14373), isolated from human adult faeces, be formally recognized as the neotype strain of Eubacterium rectale...
  7. ncbi request reprint Characteristics of sheep-rumen isolates of Pseudomonas aeruginosa inhibitory to the growth of Escherichia coli O157
    S H Duncan
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    FEMS Microbiol Lett 180:305-10. 1999
    ..Tested strains attached in large numbers to cultured rumen epithelial cells, potentially providing a means of survival in this ecosystem...
  8. ncbi request reprint Inhibitory activity of gut bacteria against Escherichia coli O157 mediated by dietary plant metabolites
    S H Duncan
    Rowett Research Institute, Bucksburn, Aberdeen, UK
    FEMS Microbiol Lett 164:283-8. 1998
    ..coli O157 in the gut. Adding esculin to incubations of mixed rumen contents significantly reduced the survival of E. coli O157...
  9. ncbi request reprint Understanding the effects of diet on bacterial metabolism in the large intestine
    P Louis
    Microbial Ecology Group, Rowett Research Institute, Aberdeen, UK
    J Appl Microbiol 102:1197-208. 2007
    ..Better understanding of the colonic microbial ecosystem will help to explain and predict the effects of dietary additives, including nondigestible carbohydrates, probiotics and prebiotics...
  10. ncbi request reprint Dietary effects on the microbiological safety of food
    E C McWilliam Leitch
    Gut Microbiology and Immunology Division, Rowett Research Institute, Bucksburn, Aberdeen, UK
    Proc Nutr Soc 60:247-55. 2001
    ..This system may prove useful for the study of dietary effects on food-borne pathogens...
  11. doi request reprint Human colonic microbiota associated with diet, obesity and weight loss
    S H Duncan
    Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, Aberdeen, UK
    Int J Obes (Lond) 32:1720-4. 2008
    ..It has been proposed that the development of obesity in humans is influenced by the relative proportions of the two major phyla of bacteria (Bacteroidetes and Firmicutes) present in the large intestine...
  12. ncbi request reprint Binding and degradation of lectins by components of rumen liquor
    K Baintner
    Rowett Research Institute, Aberdeen, Scotland, UK
    J Appl Bacteriol 74:29-35. 1993
    ..Clearly, as some lectins were not fully degraded in the rumen, they could be expected to depress the utilization of the diet not only in single-stomach animals but, possibly, also in ruminants...
  13. pmc Restricted distribution of the butyrate kinase pathway among butyrate-producing bacteria from the human colon
    Petra Louis
    Division of Gut Microbiology and Immunology, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    J Bacteriol 186:2099-106. 2004
    ....
  14. ncbi request reprint Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces
    Andreas Schwiertz
    Department of Gastrointestinal Microbiology, German Institute of Human Nutrition, Bergholz Rehbrücke
    Syst Appl Microbiol 25:46-51. 2002
    ..Based on phenotypic and phylogenetic criteria, it is proposed that the two strains from faeces be classified as a new genus and species, Anaerostipes caccae. The type strain of Anaerostipes caccae is NCIMB 13811T (= DSM 14662T)...
  15. pmc Impact of pH on lactate formation and utilization by human fecal microbial communities
    Alvaro Belenguer
    Estación Agrícola Experimental, Finca Marzanas s n, 24346 Grulleros León, Spain
    Appl Environ Microbiol 73:6526-33. 2007
    ..9, but at pH 5.2 reduced utilization occurs while production is maintained, resulting in lactate accumulation...
  16. ncbi request reprint Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications
    Wendy R Russell
    Molecular Nutrition Group, Rowett Research Institute, Aberdeen, UK
    Mol Nutr Food Res 51:726-31. 2007
    ..Studies addressing a wide-range of well-characterised human volunteers will be required before such health claims can be fully established...
  17. ncbi request reprint Interactions and competition within the microbial community of the human colon: links between diet and health
    Harry J Flint
    Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB219SB, UK
    Environ Microbiol 9:1101-11. 2007
    ..Oligosaccharides used as dietary prebiotics must inevitably have complex effects upon the bacterial community that include non-target organisms and the consequences of metabolic cross-feeding and changes in the gut environment...
  18. pmc Oxalobacter formigenes and its potential role in human health
    Sylvia H Duncan
    Gut Microbiology and Immunology Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 68:3841-7. 2002
    ....
  19. ncbi request reprint The microbiology of butyrate formation in the human colon
    Susan E Pryde
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    FEMS Microbiol Lett 217:133-9. 2002
    ....
  20. ncbi request reprint Selective colonization of insoluble substrates by human faecal bacteria
    E Carol McWilliam Leitch
    Microbial Ecology Group, Aberdeen, UK
    Environ Microbiol 9:667-79. 2007
    ..This study suggests that a specific subset of bacteria is likely to be the primary colonizers of particular insoluble colonic substrates. For a given substrate, however, the primary colonizing species may vary between host individuals...
  21. pmc Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces
    Sylvia H Duncan
    Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Appl Environ Microbiol 73:1073-8. 2007
    ..1%, and 1.9%, respectively; P = 0.026) decreased as carbohydrate intake decreased. The abundance of butyrate-producing bacteria related to Roseburia spp. and E. rectale correlated well with the decline in fecal butyrate...
  22. ncbi request reprint Proposal of Roseburia faecis sp. nov., Roseburia hominis sp. nov. and Roseburia inulinivorans sp. nov., based on isolates from human faeces
    Sylvia H Duncan
    Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Int J Syst Evol Microbiol 56:2437-41. 2006
    ..nov. (type strain A2-183(T)=DSM 16839(T)=NCIMB 14029(T)), Roseburia inulinivorans sp. nov. (type strain A2-194(T)=DSM 16841(T)=NCIMB 14030(T)) and Roseburia faecis sp. nov. (type strain M72/1(T)=DSM 16840(T)=NCIMB 14031(T))...
  23. ncbi request reprint Oxalobacter formigenes and its role in oxalate metabolism in the human gut
    Colin S Stewart
    Division of Gut Microbiology and Immunology, Rowett Research Institute, Bucksburn, Aberdeen, UK
    FEMS Microbiol Lett 230:1-7. 2004
    ..formigenes, that are able to degrade toxic compounds in the gut, may, in future, find application for therapeutic use, with substantial benefit for human health and well-being...
  24. ncbi request reprint Contribution of acetate to butyrate formation by human faecal bacteria
    Sylvia H Duncan
    Gut Microbiology and Immunology Division, Rowett Research Institute, Aberdeen, UK
    Br J Nutr 91:915-23. 2004
    ..Variations in the dominant metabolic type of butyrate producer between individuals or with variations in diet are not ruled out, however, and could influence butyrate supply in the large intestine...
  25. pmc Effects of alternative dietary substrates on competition between human colonic bacteria in an anaerobic fermentor system
    Sylvia H Duncan
    Gut Microbiology and Immunology Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 69:1136-42. 2003
    ..Thus, considerable caution is necessary when workers attempt to predict the in vivo effects of probiotics and prebiotics from their effects in vitro...
  26. pmc pH and peptide supply can radically alter bacterial populations and short-chain fatty acid ratios within microbial communities from the human colon
    Alan W Walker
    Microbial Genetics Group, Rowett Research Institute, Greenburn Rd, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 71:3692-700. 2005
    ....
  27. pmc Two routes of metabolic cross-feeding between Bifidobacterium adolescentis and butyrate-producing anaerobes from the human gut
    Alvaro Belenguer
    Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 72:3593-9. 2006
    ..adolescentis and butyrate-forming bacteria may operate in gut ecosystems, one due to consumption of fermentation end products (lactate and acetate) and the other due to cross-feeding of partial breakdown products from complex substrates...
  28. pmc Molecular diversity, cultivation, and improved detection by fluorescent in situ hybridization of a dominant group of human gut bacteria related to Roseburia spp. or Eubacterium rectale
    Rustam I Aminov
    Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 72:6371-6. 2006
    ..Most of the diversity within this important group of butyrate-producing gut bacteria can apparently be retrieved through cultivation...
  29. ncbi request reprint Application of 16S rRNA gene-targetted fluorescence in situ hybridization and restriction fragment length polymorphism to study porcine microbiota along the gastrointestinal tract in response to different sources of dietary fibre
    Marisol Castillo
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Barcelona, Spain
    FEMS Microbiol Ecol 59:138-46. 2007
    ..Restriction fragment length polymorphism profiles showed changes related to diet, with pigs fed wheat bran having the lowest richness of all diets (P=0.008)...
  30. pmc Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product
    Sylvia H Duncan
    Microbial Genetics Group, Rowett Research Institute, Greenburn Rd, Bucksburn, Aberdeen AB21 9SB, UK
    Appl Environ Microbiol 70:5810-7. 2004
    ..The abundance of E. hallii in particular in the colonic ecosystem suggests that these bacteria play important roles in preventing lactate accumulation...
  31. pmc Metabolism of linoleic acid by human gut bacteria: different routes for biosynthesis of conjugated linoleic acid
    Estelle Devillard
    Rowett Research Institute, Bucksburn, Aberdeen, AB21 9SB, United Kingdom
    J Bacteriol 189:2566-70. 2007
    ..formed either vaccenic acid (trans-11-18:1) or a 10-hydroxy-18:1; these compounds are precursors of the health-promoting conjugated linoleic acid cis-9,trans-11-18:2 in human tissues and the intestine, respectively...