Research Topics
Species | J E DrewSummaryAffiliation: Rowett Research Institute Country: UK Publications
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Detail Information
Publications
Oxidative stress in colon tissue induced by vitamin E depletionJ E Drew
Cellular Integrity, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
Biochem Soc Trans 32:979-81. 2004..These changes in colon tissue are potentially important in disease pathogenesis of the colon linked with oxidative stress or other direct consequences of inadequate levels of vitamin E...
Salicylic acid modulates oxidative stress and glutathione peroxidase activity in the rat colonJanice E Drew
Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
Biochem Pharmacol 70:888-93. 2005..The ability of salicylic acid to modulate antioxidant enzymes in colon tissue may be an important mechanism in inhibiting colon cancer development...
Insulin, leptin, and adiponectin receptors in colon: regulation relative to differing body adiposity independent of diet and in response to dimethylhydrazineJanice E Drew
Gut Health Division, Rowett Research Institute, Greenburn Rd, Bucksburn, Aberdeen, AB21 9SB, Scotland, UK
Am J Physiol Gastrointest Liver Physiol 293:G682-91. 2007..These findings do not support a direct link between the deregulation of insulin and adipokine levels observed in obese rats and an increased risk of colon carcinogenesis...
Complex regulation of mucosal pentraxin (Mptx) revealed by discrete micro-anatomical locations in colonJanice E Drew
Molecular Nutrition, Gut Health, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
Biochim Biophys Acta 1762:844-8. 2006..This study demonstrates that consideration of regional differences in Mptx gene expression and micro-anatomical location is necessary in the interpretation and deciphering of its regulation in colon...
Inhibition of cytokine-induced prostanoid biogenesis by phytochemicals in human colonic fibroblastsWendy R Russell
Gut Health Division, Molecular Nutrition Group, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
Biochim Biophys Acta 1762:124-30. 2006..Common structural features of the inhibitors were the presence of 4-hydroxyl and 3-methoxyl substituents on the aromatic ring and/or the presence of a three-carbon side-chain on C1...
Salicylate modulates oxidative stress in the rat colon: a proteomic approachJanice E Drew
Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB Scotland, UK
Biochem Pharmacol 72:204-16. 2006....
Influence of increased adiposity on mitochondrial-associated proteins of the rat colon: a proteomic and transcriptomic analysisSara Padidar
Molecular Nutrition, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB, Scotland, UK
Biochim Biophys Acta 1782:532-41. 2008..The changes in these mitochondrial protein profiles were not correlated with changes at the gene expression level assessed using real-time PCR arrays...
Anti-inflammatory implications of the microbial transformation of dietary phenolic compoundsWendy R Russell
Molecular Nutrition Group, Rowett Research Institute, Aberdeen, United Kingdom
Nutr Cancer 60:636-42. 2008..This suggests that the microbial transformation of dietary compounds will have important inflammatory implications in the chemoprevention of colon cancer...
Novel sites of cytosolic glutathione peroxidase expression in colonJanice E Drew
Gut Health Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
FEBS Lett 579:6135-9. 2005..These results support the potential for Gpx1 and Gpx2 redundancy in lymphatic tissue, but not in epithelial cells of the colon crypt or in the lamina propria, sub-mucosa, muscularis or serosa...
Localization of the melatonin-related receptor in the rodent brain and peripheral tissuesJ E Drew
Molecular Neuroendocrinology Group, Rowett Research Institute, Bucksburn, Aberdeen, UK
J Neuroendocrinol 13:453-8. 2001..These results suggest a conserved function in neuroendocrine regulation and a potential role in coordinating physiological responses in the central nervous system and peripheral tissues...
Profiling of mitochondrial associated proteins from rat colonSara Padidar
Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
J Cell Biochem 103:78-97. 2008....
