S Roberts

Summary

Affiliation: Robert Jones and Agnes Hunt Orthopaedic Hospital
Country: UK

Publications

  1. pmc Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis
    Mitsuhiko Sato
    Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki 23, Eiheiji, Fukui 910 1193, Japan
    Arthritis Res Ther 14:R31. 2012
  2. pmc Microarray analysis of expression of cell death-associated genes in rat spinal cord cells exposed to cyclic tensile stresses in vitro
    Kenzo Uchida
    Department of Orthopaedics and Rehabilitation Medicine, Fukui University Faculty of Medical Sciences, Shimoaizuki 23, Matsuoka, Fukui 910 1193, Japan
    BMC Neurosci 11:84. 2010
  3. pmc Intervertebral disc cells as competent phagocytes in vitro: implications for cell death in disc degeneration
    Philip Jones
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic and District Hospital NHS Trust, Oswestry, Shropshire, UK
    Arthritis Res Ther 10:R86. 2008
  4. pmc Glycosaminoglycan profiles of repair tissue formed following autologous chondrocyte implantation differ from control cartilage
    Aarti Sharma
    Institute of Science and Technology in Medicine, University of Keele, Staffordshire, ST5 5BG, UK
    Arthritis Res Ther 9:R79. 2007
  5. pmc The influence of serum, glucose and oxygen on intervertebral disc cell growth in vitro: implications for degenerative disc disease
    William E B Johnson
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, SY10 7AG, UK
    Arthritis Res Ther 10:R46. 2008
  6. pmc Immunohistochemical study of collagen types I and II and procollagen IIA in human cartilage repair tissue following autologous chondrocyte implantation
    S Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, UK
    Knee 16:398-404. 2009
  7. pmc Senescence in human intervertebral discs
    S Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic and District Hospital, NHS Trust, Oswestry, Shropshire, SY10 7AG, UK
    Eur Spine J 15:S312-6. 2006
  8. ncbi request reprint Histology and pathology of the human intervertebral disc
    Sally Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Oswestry, Shropshire SY10 7AG, United Kingdom
    J Bone Joint Surg Am 88:10-4. 2006
  9. doi request reprint Prospects of stem cell therapy in osteoarthritis
    Sally Roberts
    Tissue Engineering Centre, Arthritis Research UK, UK
    Regen Med 6:351-66. 2011
  10. pmc Bovine explant model of degeneration of the intervertebral disc
    Sally Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SY10 7AG, UK
    BMC Musculoskelet Disord 9:24. 2008

Collaborators

Detail Information

Publications57

  1. pmc Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis
    Mitsuhiko Sato
    Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki 23, Eiheiji, Fukui 910 1193, Japan
    Arthritis Res Ther 14:R31. 2012
    ..The aim of this study was to test the outcome of intra-articular transplantation of mesenchymal stem cells suspended in hyaluronic acid (HA) in the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis (OA)...
  2. pmc Microarray analysis of expression of cell death-associated genes in rat spinal cord cells exposed to cyclic tensile stresses in vitro
    Kenzo Uchida
    Department of Orthopaedics and Rehabilitation Medicine, Fukui University Faculty of Medical Sciences, Shimoaizuki 23, Matsuoka, Fukui 910 1193, Japan
    BMC Neurosci 11:84. 2010
    ..Changes in expression of 12 genes were validated with quantitative real-time reverse transcription polymerase chain reaction (RT-PCR)...
  3. pmc Intervertebral disc cells as competent phagocytes in vitro: implications for cell death in disc degeneration
    Philip Jones
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic and District Hospital NHS Trust, Oswestry, Shropshire, UK
    Arthritis Res Ther 10:R86. 2008
    ..We investigated whether disc cells themselves can be induced to become phagocytic and so have the ability to ingest and remove apoptotic disc cells, minimising the damage to their environment...
  4. pmc Glycosaminoglycan profiles of repair tissue formed following autologous chondrocyte implantation differ from control cartilage
    Aarti Sharma
    Institute of Science and Technology in Medicine, University of Keele, Staffordshire, ST5 5BG, UK
    Arthritis Res Ther 9:R79. 2007
    ..The composition of the repair tissue thus is not identical to mature articular cartilage...
  5. pmc The influence of serum, glucose and oxygen on intervertebral disc cell growth in vitro: implications for degenerative disc disease
    William E B Johnson
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, SY10 7AG, UK
    Arthritis Res Ther 10:R46. 2008
    ..Therefore, we have examined the relative influence of possible blood-borne factors on the growth characteristics of IVD cells in vitro...
  6. pmc Immunohistochemical study of collagen types I and II and procollagen IIA in human cartilage repair tissue following autologous chondrocyte implantation
    S Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, UK
    Knee 16:398-404. 2009
    ..This suggests that cartilage repair tissue produced following ACI treatment, is likely to take some years to mature...
  7. pmc Senescence in human intervertebral discs
    S Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic and District Hospital, NHS Trust, Oswestry, Shropshire, SY10 7AG, UK
    Eur Spine J 15:S312-6. 2006
    ....
  8. ncbi request reprint Histology and pathology of the human intervertebral disc
    Sally Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Oswestry, Shropshire SY10 7AG, United Kingdom
    J Bone Joint Surg Am 88:10-4. 2006
    ..Whatever the initial cause, a change in the morphology of the tissue is likely to alter the physiologic and mechanical functioning of the tissue...
  9. doi request reprint Prospects of stem cell therapy in osteoarthritis
    Sally Roberts
    Tissue Engineering Centre, Arthritis Research UK, UK
    Regen Med 6:351-66. 2011
    ..However, this would not be an issue if endogenous stem cells were activated to effect repair of an arthritic joint...
  10. pmc Bovine explant model of degeneration of the intervertebral disc
    Sally Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SY10 7AG, UK
    BMC Musculoskelet Disord 9:24. 2008
    ..Bovine explant model systems have many advantages but it is not possible to inject any significant volume into an intact disc. Therefore we have attempted to mimic disc degeneration in an explant bovine model via enzymatic digestion...
  11. ncbi request reprint Matrix turnover in human cartilage repair tissue in autologous chondrocyte implantation
    S Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, National Health Service Trust, Oswestry, Shropshire, UK
    Arthritis Rheum 44:2586-98. 2001
    ..We examined biopsy samples from the graft site using a panel of specific antibodies to investigate the cellular mechanisms involved and to determine whether remodeling of the matrix occurs...
  12. ncbi request reprint Mechanoreceptors in intervertebral discs. Morphology, distribution, and neuropeptides
    S Roberts
    J P O Brien Laboratory, Centre for Spinal Studies, RJAH Orthopaedic and District Hospital, Oswestry, Shropshire, UK
    Spine (Phila Pa 1976) 20:2645-51. 1995
    ..Their presence in the intervertebral disc and longitudinal ligament can have physiologic and clinical implications...
  13. ncbi request reprint Matrix metalloproteinases and aggrecanase: their role in disorders of the human intervertebral disc
    S Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, UK
    Spine (Phila Pa 1976) 25:3005-13. 2000
    ..A comprehensive immunohistochemical study of matrix metalloproteinase activity in discs from patients with different disc diseases...
  14. ncbi request reprint Transport properties of the human cartilage endplate in relation to its composition and calcification
    S Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic and District Hospital NHS Trust, Oswestry
    Spine (Phila Pa 1976) 21:415-20. 1996
    ..Hence, a major function of the cartilage endplate may be to prevent fragments of osmotically active proteoglycans from leaving the disc...
  15. ncbi request reprint Cell cluster formation in degenerate lumbar intervertebral discs is associated with increased disc cell proliferation
    W E Johnson
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, UK
    Connect Tissue Res 42:197-207. 2001
    ..These observations suggest that disc cell proliferation is associated with disc degeneration and is the likely cause of cell cluster formation...
  16. ncbi request reprint 1991 Volvo Award in basic sciences. Collagen types around the cells of the intervertebral disc and cartilage end plate: an immunolocalization study
    S Roberts
    Charles Salt Research Centre, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, England
    Spine (Phila Pa 1976) 16:1030-8. 1991
    ..In pathologic tissue the amount and distribution of the collagen types, and the organization of the pericellular capsule, differ from that seen in control material...
  17. ncbi request reprint Human intervertebral disc aggrecan inhibits nerve growth in vitro
    William E B Johnson
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SY10 7AG, UK
    Arthritis Rheum 46:2658-64. 2002
    ..To assess the effects of human intervertebral disc aggrecan on nerve growth and guidance, using in vitro techniques...
  18. ncbi request reprint Immunohistochemical detection of Schwann cells in innervated and vascularized human intervertebral discs
    W E Johnson
    J P O Brien Laboratory, Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SY10 7AG, United Kingdom
    Spine (Phila Pa 1976) 26:2550-7. 2001
    ..The ingrowth of nerves, blood vessels, and Schwann cells into human intervertebral discs was examined using immunohistochemistry for cell-type-specific markers...
  19. ncbi request reprint The presence of pleiotrophin in the human intervertebral disc is associated with increased vascularization: an immunohistologic study
    William E B Johnson
    Centre for Spinal Studies, Institute for Science and Technology in Medicine of Keele University, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, United Kingdom
    Spine (Phila Pa 1976) 32:1295-302. 2007
    ..An immunohistological study of surgical specimens of human intervertebral disc...
  20. pmc Disc cell clusters in pathological human intervertebral discs are associated with increased stress protein immunostaining
    Christopher A Sharp
    Charles Salt Centre for Human Metabolism, Robert Jones and Agnes Hunt Orthopaedic and District Hospital NHS Trust, Oswestry, Shropshire SY10 7AG, UK
    Eur Spine J 18:1587-94. 2009
    ..A better understanding of the stress response in IVD cells may allow its utilization in disc cell therapies...
  21. ncbi request reprint Human intervertebral disc cells promote nerve growth over substrata of human intervertebral disc aggrecan
    William E B Johnson
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, United Kingdom
    Spine (Phila Pa 1976) 31:1187-93. 2006
    ..Coculture assays of the migration and interaction of human intervertebral disc cells and chick sensory nerves on alternate substrata of collagen and aggrecan...
  22. ncbi request reprint Human intervertebral disc aggrecan inhibits endothelial cell adhesion and cell migration in vitro
    William E B Johnson
    J P O Brien Laboratory, Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, United Kingdom
    Spine (Phila Pa 1976) 30:1139-47. 2005
    ..The effect of human intervertebral disc aggrecan on endothelial cell growth was examined using cell culture assays...
  23. ncbi request reprint Inflammatory mediators as potential therapeutic targets in the spine
    Sally Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SY10 7AG, UK
    Curr Drug Targets Inflamm Allergy 4:257-66. 2005
    ....
  24. ncbi request reprint Autologous chondrocyte implantation in knee joint: MR imaging and histologic features at 1-year follow-up
    Bernhard J Tins
    Department of Radiology, Robert Jones and Agnes Hunt Orthopaedic and District Hospital, Oswestry SY10 7AG, England
    Radiology 234:501-8. 2005
    ..To evaluate magnetic resonance (MR) imaging features of autologous chondrocyte implantation (ACI) grafts and compare these with graft histologic features 1 year after ACI for treatment of femoral condylar defects...
  25. pmc TNFalpha-stimulated gene product (TSG-6) and its binding protein, IalphaI, in the human intervertebral disc: new molecules for the disc
    Sally Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital and Keele University, Oswestry, Shropshire, SY10 7AG, UK
    Eur Spine J 14:36-42. 2005
    ..Hence, the occurrence of TSG-6 and IalphaI in disc tissue could have implications in the aetiopathogenesis and future therapeutics of intervertebral disc disease...
  26. ncbi request reprint Cells from different regions of the intervertebral disc: effect of culture system on matrix expression and cell phenotype
    Heather A Horner
    Physiology Laboratory, Oxford University, Oxford, and the Centre for Spinal Studies, RJAH Orthopaedic Hospital, Oswestry, Shropshire, United Kingdom
    Spine (Phila Pa 1976) 27:1018-28. 2002
    ..This study examined how the culture system and region of cellular origin affect disc cell morphology and extracellular matrix production...
  27. pmc Topographical guidance of intervertebral disc cell growth in vitro: towards the development of tissue repair strategies for the anulus fibrosus
    William E Johnson
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, UK
    Eur Spine J 15:S389-96. 2006
    ..However, there is a need to optimise cell sources and/or environmental conditions (e.g. mechanical influences) to promote the synthesis of an aligned ECM...
  28. ncbi request reprint 'Rumours of my death may have been greatly exaggerated': a brief review of cell death in human intervertebral disc disease and implications for cell transplantation therapy
    W E B Johnson
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SY10 7AG, UK
    Biochem Soc Trans 35:680-2. 2007
    ....
  29. ncbi request reprint Innervation of the spondylolysis "ligament"
    S M Eisenstein
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, United Kingdom
    Spine (Phila Pa 1976) 19:912-6. 1994
    ..CONCLUSION. The movement that the ligament allows at the fracture site may result in stimulation of the nerve endings both in the ligament and in the surrounding soft tissue...
  30. ncbi request reprint Combined autologous chondrocyte implantation and allogenic meniscus transplantation: a biological knee replacement
    A M Bhosale
    Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Oswestry, SY10 7AG Shropshire, United Kingdom
    Knee 14:361-8. 2007
    ..2 years. We could not find any deleterious effects of the combination of these two techniques. So we conclude that the combination of these two techniques together may act a one step towards a true biological knee replacement...
  31. ncbi request reprint The cell culture expansion of bone marrow stromal cells from humans with spinal cord injury: implications for future cell transplantation therapy
    K T Wright
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, UK
    Spinal Cord 46:811-7. 2008
    ..Here, we have examined the growth in cell culture of MSCs isolated from individuals with SCI, compared with non-SCI donors...
  32. pmc Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology
    Sally Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Oswestry, Shropshire, UK
    Arthritis Res Ther 5:R60-73. 2003
    ..MRI scans provide a useful assessment of properties of the whole graft area and adjacent tissue and is a noninvasive technique for long-term follow-up. It correlated with histology (P = 0.02) in patients treated with ACI alone...
  33. ncbi request reprint The physiology of the disc and its clinical relevance
    S Eisenstein
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, England
    J Bone Joint Surg Br 85:633-6. 2003
  34. ncbi request reprint The Avon patellofemoral joint replacement: independent assessment of early functional outcomes
    I Starks
    Robert Jones and Agnes Hunt Orthopaedic Hospital, Gobowen, Shropshire, UK
    J Bone Joint Surg Br 91:1579-82. 2009
    ..Only one patient reported an unsatisfactory outcome. We conclude that the promising early results observed by the designing centre are reproducible and provide further support for the role of patellofemoral joint replacement...
  35. ncbi request reprint Biochemical and structural properties of the cartilage end-plate and its relation to the intervertebral disc
    S Roberts
    Charles Salt Research Centre, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, England
    Spine (Phila Pa 1976) 14:166-74. 1989
    ..Where these occurred, the disc, and in some cases the end-plate, showed loss of proteoglycan compared with the surrounding tissue...
  36. ncbi request reprint A histological comparison of the repair tissue formed when using either Chondrogide(®) or periosteum during autologous chondrocyte implantation
    H S McCarthy
    Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust and ISTM, Keele University, Oswestry, Shropshire SY10 7AG, UK Electronic address
    Osteoarthritis Cartilage 21:2048-57. 2013
    ..In this study, we compare the clinical and histological outcome between periosteum and Chondrogide(®) during autologous chondrocyte implantation (ACI)...
  37. ncbi request reprint Microscopic methods for the analysis of engineered tissues
    Sally Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Owestry, Shropshire, UK
    Methods Mol Biol 238:171-96. 2004
  38. ncbi request reprint Disc morphology in health and disease
    S Roberts
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SY10 7AG, UK
    Biochem Soc Trans 30:864-9. 2002
    ..This may lead to an increased supply of oxygen and nutrients to the disc, but can also introduce other cells types and molecules such as cytokines and growth factors...
  39. ncbi request reprint Bone marrow stromal cells stimulate neurite outgrowth over neural proteoglycans (CSPG), myelin associated glycoprotein and Nogo-A
    Karina T Wright
    Centre for Spinal Studies, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire SY10 7AG, UK
    Biochem Biophys Res Commun 354:559-66. 2007
    ..These findings suggest that MSC transplantation may promote axonal regeneration both by stimulating nerve growth via secreted factors and also by reducing the nerve-inhibitory effects of the extracellular molecules present...
  40. doi request reprint Collagen turnover in normal and degenerate human intervertebral discs as determined by the racemization of aspartic acid
    Sarit Sara Sivan
    Department of Biomedical Engineering, Technion Israel Institute of Technology, Haifa, Israel
    J Biol Chem 283:8796-801. 2008
    ....
  41. ncbi request reprint A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at five years
    Gunnar Knutsen
    Department of Orthopaedic Surgery, University of Tromsø, University Hospital North Norway, 9038 Tromsø, Norway
    J Bone Joint Surg Am 89:2105-12. 2007
    ..The objective of this randomized trial was to compare autologous chondrocyte implantation with microfracture. This paper represents an update, with presentation of the clinical results at five years...
  42. ncbi request reprint Increased nerve and blood vessel ingrowth associated with proteoglycan depletion in an ovine anular lesion model of experimental disc degeneration
    James Melrose
    Institute of Bone and Joint Research, at the Royal North Shore Hospital, University of Sydney, Department of Surgery, NSW, Australia
    Spine (Phila Pa 1976) 27:1278-85. 2002
    ..Nerves and blood vessel distribution in discs were localized immunohistochemically and correlated with the proteoglycan contents of normal and degenerate disc tissues...
  43. ncbi request reprint Aggrecan turnover in human intervertebral disc as determined by the racemization of aspartic acid
    Sarit S Sivan
    Department of Biomedical Engineering, Technion Israel Institute of Technology, Haifa 32000, Israel
    J Biol Chem 281:13009-14. 2006
    ....
  44. pmc Microfibrils, elastin fibres and collagen fibres in the human intervertebral disc and bovine tail disc
    Jing Yu
    Department of Physiology, Anatomy and Genetics, University of Oxford, UK
    J Anat 210:460-71. 2007
    ..The results of this study suggest the microfibrillar network of the annulus may play a mechanical role while that around the cells of the nucleus may be more involved in regulating cell function...
  45. ncbi request reprint Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial
    Gunnar Knutsen
    Department of Orthopaedic Surgery, University Hospital Tromsø, 9038 Tromsø, Norway
    J Bone Joint Surg Am 86:455-64. 2004
    ..The objective of the present study was to compare autologous chondrocyte implantation with microfracture in a randomized trial. We are not aware of any previous randomized studies comparing these methods...
  46. ncbi request reprint Promoting healthy sight and eye care
    Cheryl Holman
    City University, St Bartholomew School of Nursing and Midwifery, London
    Nurs Older People 17:37-8. 2005
  47. ncbi request reprint Value of broth cultures in detecting methicillin-resistant Staphylococcus aureus
    Sally Roberts
    N Z Med J 115:U191. 2002
  48. ncbi request reprint The elastic fiber network of the anulus fibrosus of the normal and scoliotic human intervertebral disc
    Jing Yu
    University Laboratory of Physiology, Oxford University, Oxford, United Kingdom
    Spine (Phila Pa 1976) 30:1815-20. 2005
    ..Immunohistochemical study of elastic fibers in human intervertebral discs (IVD) collected at surgery from patients with scoliosis...
  49. ncbi request reprint Promoting adequate hydration in older people
    Cheryl Holman
    Nurs Older People 17:31-2. 2005
  50. ncbi request reprint Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias
    Richard A Watson
    Cancer Research UK Institute for Cancer Studies, The Medical School, University of Birmingham, UK
    Carcinogenesis 23:1791-6. 2002
    ..In invasive squamous cell carcinomas, total cellular hDlg levels are greatly reduced. Our data suggest that loss of hDlg at sites of intercellular contact may be an important step in the development of epithelial cancers...
  51. ncbi request reprint Autologous chondrocyte implantation with bone grafting for osteochondral defect due to posttraumatic osteonecrosis of the hip--a case report
    Pavel Akimau
    Institute of Orthopaedics, Leopold Muller Arthritis Research Centre, UK
    Acta Orthop 77:333-6. 2006
  52. pmc Elastic fibre organization in the intervertebral discs of the bovine tail
    Jing Yu
    Laboratory of Physiology, Oxford University, UK
    J Anat 201:465-75. 2002
    ..The varying organization of the elastic fibres in the different regions of the disc is likely to relate to the different regional loading patterns...
  53. ncbi request reprint Using drawing to explore student nurses' perceptions of older age
    Sally Roberts
    City University, St Bartholomew s School of Nursing and Midwifery, London
    Nurs Older People 15:14-8. 2003
  54. ncbi request reprint Redistribution of the discs large tumor suppressor protein during mitosis
    Paola Massimi
    International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I 34012 Trieste, Italy
    Exp Cell Res 290:265-74. 2003
    ..We conclude that localisation of Dlg to the midbody indicates a role for Dlg at this critical point in cytokinesis...
  55. ncbi request reprint Histological assessment of cartilage repair: a report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS)
    Pierre Mainil-Varlet
    Institute of Pathology, University of Bern, Switzerland
    J Bone Joint Surg Am 85:45-57. 2003
  56. pmc Degeneration of the intervertebral disc
    Jill P G Urban
    University Laboratory of Physiology, Oxford University, Oxford, UK
    Arthritis Res Ther 5:120-30. 2003
    ..New developments, such as genetic and biological approaches, may allow better diagnosis and treatments in the future...
  57. pmc Cooperation between different forms of the human papillomavirus type 1 E4 protein to block cell cycle progression and cellular DNA synthesis
    Gillian L Knight
    Cancer Research UK Institute for Cancer Studies, University of Birmingham, Vincent Dr, Edgbaston, Birmingham B15 2TT, United Kingdom
    J Virol 78:13920-33. 2004
    ..We predict that these distinct biological activities of E4 act to support efficient amplification of the viral genome in suprabasal keratinocytes...