T M Reynolds
- National Institute for Health and Clinical Excellence guidelines on preoperative tests: the use of routine preoperative tests for elective surgeryT M Reynolds
Clinical Chemistry Department, Queen s Hospital, Belvedere Road, Burton on Trent, Staffordshire DE13 0RB, UK
Ann Clin Biochem 43:13-6. 2006..The resultant matrix may be suitable for use as a template for future research, but is extremely complex and inadequately rigorous for routine use...
- Down's syndrome risk estimates demonstrate considerable heterogeneity despite homogeneity of inputTim Reynolds
Clinical Chemistry Dept, Queen s Hospital, Burton on Trent, UK and Division of Sciences, Wolverhampton University, Wolverhampton, UK
Ann Clin Biochem 41:464-8. 2004..Due to concerns about screening quality, Down's syndrome screening laboratories were surveyed to identify the range of variation in risk-calculation software...
- Assessment of a prognostic biochemical indicator of nutrition and inflammation for identification of pressure ulcer riskT M Reynolds
Clinical Chemistry Department, Queen s Hospital, Burton on Trent, Staffordshire, UK
J Clin Pathol 59:308-10. 2006..Pressure ulcers represent a major cost to the healthcare systems of the world but preventative measures are expensive and could be better targeted. Current risk screening mechanisms are often subjective and could be improved...
- Risk assessment for prevention of morbidity and mortality: lessons for pressure ulcer preventionT M Reynolds
Department of Clinical Chemistry, Queen s Hospital, Burton upon Trent, UK
J Tissue Viability 17:115-20. 2008..Finally, this paper details some suggestions for future research to combine risk tests that may offer a prospect for improving ulcer risk screening tools...
- Evaluation of Down's syndrome screening population data sets by simulation: analyser-specific parameters may be superior to meta-analysis-derived parametersT M Reynolds
Division of Clinical Sciences, Queens Hospital, Wolverhampton University, Burton on Trent, Staffordshire, UK
Int J Clin Pract 62:735-43. 2008..Choice of parameter sets used to calculate Down's syndrome risks is complicated. Published population statistics were compared with assay-specific parameters to optimise screening efficiency...
- Median parameters for Down's syndrome screening should be calculated using a moving time-window methodT M Reynolds
Clinical Chemistry Department, Queen s Hospital, Belvedere Road, Burton on Trent, Staffordshire DE13 0RB
Ann Clin Biochem 45:567-70. 2008..DQASS recommends monitoring by cumulative sum plot...
- Weight correction of MoM values: which method?T M Reynolds
Queens Hospital, Burton on Trent, Staffordshire, UK
J Clin Pathol 59:753-8. 2006..The choice of model for taking maternal weight into account is, however, rarely explicitly evaluated...
- Down's syndrome screening: a controversial test, with more controversy to come!T M Reynolds
Queen s Hospital and Division of Clinical Sciences, Wolverhampton University, Wolverhampton WV1 1SB, UK
J Clin Pathol 53:893-8. 2000..Furthermore, if a national policy is decided upon, worldwide patent searches should be carried out to determine whether there are any possible unforeseen legal consequences of any recommendation...
- Targeting treatment using calculated cardiovascular disease risk: effective? A shot in the dark? Or is it time to change the paradigm?T M Reynolds
Clinical Chemistry Department, Queen s Hospital, Burton on Trent, UK
Int J Clin Pract 63:1785-91. 2009..This is marginally effective with somewhere between 199 and 999 people receiving lipid-lowering therapy and consequently being exposed to the drug-related risk without receiving any benefit...
- How accurate are pressure ulcer grades? An image-based survey of nurse performanceL J Russell
Queen s Hospital, Burton on Trent
J Tissue Viability 11:67, 70-5. 2001....
- Using image analysis to determine cause, severity, status and healing prognosis in wound managementL Russell
Burton Hospitals NHS Trust, Burton on Trent, UK
J Wound Care 14:433-6. 2005..It is vital to evaluate the visual appearance of a wound when considering potential management options. However, where human vision lacks precision, image analysis has been shown to offer a more reliable method of assessment...
- Randomized comparison trial of the RIK and the Nimbus 3 mattressesL Russell
Queen s Hospital, Burton on Trent, Staffordshire
Br J Nurs 12:254, 256-9. 2003..For a significant proportion of patients, a static (RIK) mattress can be as effective as an active (Nimbus 3) mattress for management of pressure ulcers...
- Haemoglobin Le Lamentin (alpha 20 (B1) His-->Gln) in a British family: identification by electrospray mass spectrometryT M Reynolds
Queen s Hospital, Burton on Trent, Staffordshire, UK Clinical Chemistry Department
J Clin Pathol 51:467-70. 1998..Identification of the haemoglobin variant was by electrospray mass spectrometry...
- The role of CA125 in clinical practiceE L Moss
Department of Obstetrics and Gynaecology, Queen s Hospital, Belvedere Road, Burton upon Trent, Staffordshire DE13 0RB, UK
J Clin Pathol 58:308-12. 2005..The sensitivity and specificity of CA125 are poor and there are no guidelines produced by the Royal College of Pathologists or the Association of Clinical Biochemists to aid clinicians and laboratories in its most appropriate use...
- The future of nutrition and wound healingT M Reynolds
Queen's Hospital, Division of Clinical Sciences, Wolverhampton, UK
J Tissue Viability 11:5-13. 2001..This review considers the nutritional factors affecting wound healing and some developments that may alter the future of therapy...
- Comparison between transcutaneous bilirubinometry and total serum bilirubin measurements in preterm infants <35 weeks gestationM Ahmed
Department of Paediatrics, Queen s Hospital, Burton upon Trent, UK
Ann Clin Biochem 47:72-7. 2010..However, repeated blood sampling is not only traumatic but may also be a cause of anaemia in neonates. We evaluated a transcutaneous bilirubin assay method to determine whether it was suitable for routine use in preterm infants...
- Down's syndrome screening is unethical: views of today's research ethics committeesT M Reynolds
Clinical Chemistry Department, Queen s Hospital, Burton on Trent, Staffordshire, UK
J Clin Pathol 56:268-70. 2003..This study investigated the attitudes of research ethics committee members to several conditions varying in clinical severity and prognosis, including Down's syndrome...
- Down's syndrome screening: population statistic dependency of screening performanceTim Reynolds
Queens Hospital Burton on Trent, Clinical Chemistry Department, Staffordshire, UK
Clin Chem Lab Med 46:639-47. 2008..Screening efficiency realized with measurement procedure-specific population parameters is compared with selected population sets available in the literature...
- Screening for Down's syndrome. Conclusions do not reflect realityTim Reynolds
BMJ 324:111. 2002
- A regression analysis of the Waterlow score in pressure ulcer risk assessmentDenis Anthony
Mary Seacole Research Centre, School of Nursing and Midwifery, De Montfort University, Leicester, UK
Clin Rehabil 17:216-23. 2003..To explore the predictive value of the Waterlow score, and the subscores of age and gender...
- Giving antioxidants to infants with Down's syndromeTim Reynolds
BMJ 336:568-9. 2008
- Ethnicity in pressure ulcer risk assessment, with specific relation to the Pakistani ethnic minority in Burton, EnglandDenis Anthony
Nursing Informatics, Mary Seacole Research Centre, School of Nursing and Midwifery, De Montfort University, Leicester, UK
J Adv Nurs 38:592-7. 2002..There has been little work on ethnicity related to pressure ulcers in general and little or nothing specific to South Asians, and the Pakistani ethnic group in particular...
- The potential risk from 222radon posed to archaeologists and earth scientists: reconnaissance study of radon concentrations, excavations, and archaeological shelters in the Great Cave of Niah, Sarawak, MalaysiaGavin Gillmore
School of Archaeological and Environmental Sciences, University of Bradford, Bradford BD7 1DP, UK
Ecotoxicol Environ Saf 60:213-27. 2005..42 mSv). The data here presented also demonstrate that there is considerable local variation in radon levels in such environments as these...
- Preoperative axillary staging in breast cancer-saving time and resourcesMohammad Tahir
Department of Breast Surgery, Queen s Hospital, Queens Hospital Burton on Trent, Staffordshire DE13 0RB, UK
Breast J 14:369-71. 2008..These cases can be planned for axillary lymph nodes clearance straightaway therefore saving patients from undergoing further surgery as well as time and resources...