Grzegorz Skibinski

Summary

Affiliation: Queen's University Belfast
Country: UK

Publications

  1. ncbi The role of hepatocyte growth factor/c-met interactions in the immune system
    Grzegorz Skibinski
    Respiratory Research Group, Department of Clinical Biochemistry, Institute of Clinical Science, Queen s University of Belfast, Belfast BT12 6BJ, Northern Ireland, UK
    Arch Immunol Ther Exp (Warsz) 51:277-82. 2003
  2. pmc The role of hepatocyte growth factor and its receptor c-met in interactions between lymphocytes and stromal cells in secondary human lymphoid organs
    G Skibinski
    Department of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, UK
    Immunology 102:506-14. 2001
  3. ncbi Hepatocyte growth factor (HGF) protects c-met-expressing Burkitt's lymphoma cell lines from apoptotic death induced by DNA damaging agents
    G Skibinski
    Department of Clinical and Surgical Sciences, University of Edinburgh, Royal Infirmary, Edinburgh EH3 9YW, UK
    Eur J Cancer 37:1562-9. 2001
  4. ncbi Bronchial epithelial cell growth regulation in fibroblast cocultures: the role of hepatocyte growth factor
    Grzegorz Skibinski
    Respiratory Medicine Research Cluster, School of Medicine and Dentistry, Queen s University Belfast, Belfast, Northern Ireland, United Kingdom
    Am J Physiol Lung Cell Mol Physiol 293:L69-76. 2007
  5. pmc Chronic IL9 and IL-13 exposure leads to an altered differentiation of ciliated cells in a well-differentiated paediatric bronchial epithelial cell model
    Jeremy C Parker
    Centre for Infection and Immunity, Queen s University Belfast, Belfast, Northern Ireland
    PLoS ONE 8:e61023. 2013
  6. doi A 3-D well-differentiated model of pediatric bronchial epithelium demonstrates unstimulated morphological differences between asthmatic and nonasthmatic cells
    Jeremy Parker
    Centre for Infection and Immunity and School of Medicine, Queen s University Belfast, Belfast, BT12 6BN, Northern Ireland
    Pediatr Res 67:17-22. 2010
  7. doi Effects of IL-13 on mucociliary differentiation of pediatric asthmatic bronchial epithelial cells
    Surendran Thavagnanam
    Centre for Infection and Immunity, Queen s University Belfast, Belfast BT12 6BN, Northern Ireland, United Kingdom
    Pediatr Res 69:95-100. 2011
  8. pmc Cytopathogenesis of Sendai virus in well-differentiated primary pediatric bronchial epithelial cells
    Remi Villenave
    Queen s University Belfast, Medical Biology Centre, Belfast BT9 7BL, Northern Ireland
    J Virol 84:11718-28. 2010
  9. pmc Differential cytopathogenesis of respiratory syncytial virus prototypic and clinical isolates in primary pediatric bronchial epithelial cells
    Remi Villenave
    Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, Belfast BT9 7BL, Northern Ireland
    Virol J 8:43. 2011
  10. doi Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma
    Claire A Butler
    Centre for Infection and Immunity, Queens University Belfast, Level 8, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, Northern Ireland, UK
    Thorax 67:392-8. 2012

Collaborators

Detail Information

Publications12

  1. ncbi The role of hepatocyte growth factor/c-met interactions in the immune system
    Grzegorz Skibinski
    Respiratory Research Group, Department of Clinical Biochemistry, Institute of Clinical Science, Queen s University of Belfast, Belfast BT12 6BJ, Northern Ireland, UK
    Arch Immunol Ther Exp (Warsz) 51:277-82. 2003
    ..This paper discusses expression of HGF and c-met within the immune system and their interactions in the control of immune cell functions...
  2. pmc The role of hepatocyte growth factor and its receptor c-met in interactions between lymphocytes and stromal cells in secondary human lymphoid organs
    G Skibinski
    Department of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, UK
    Immunology 102:506-14. 2001
    ..In this way HGF may indirectly influence immunoglobulin secretion by B cells...
  3. ncbi Hepatocyte growth factor (HGF) protects c-met-expressing Burkitt's lymphoma cell lines from apoptotic death induced by DNA damaging agents
    G Skibinski
    Department of Clinical and Surgical Sciences, University of Edinburgh, Royal Infirmary, Edinburgh EH3 9YW, UK
    Eur J Cancer 37:1562-9. 2001
    ..Overall, these studies suggest that the accumulation of HGF within the microenvironment of neoplastic cells may contribute to the development of a chemoresistant phenotype...
  4. ncbi Bronchial epithelial cell growth regulation in fibroblast cocultures: the role of hepatocyte growth factor
    Grzegorz Skibinski
    Respiratory Medicine Research Cluster, School of Medicine and Dentistry, Queen s University Belfast, Belfast, Northern Ireland, United Kingdom
    Am J Physiol Lung Cell Mol Physiol 293:L69-76. 2007
    ....
  5. pmc Chronic IL9 and IL-13 exposure leads to an altered differentiation of ciliated cells in a well-differentiated paediatric bronchial epithelial cell model
    Jeremy C Parker
    Centre for Infection and Immunity, Queen s University Belfast, Belfast, Northern Ireland
    PLoS ONE 8:e61023. 2013
    ..This suggests an alternative role for IL-9 in airways remodelling and reaffirms IL-9 as a potential therapeutic target...
  6. doi A 3-D well-differentiated model of pediatric bronchial epithelium demonstrates unstimulated morphological differences between asthmatic and nonasthmatic cells
    Jeremy Parker
    Centre for Infection and Immunity and School of Medicine, Queen s University Belfast, Belfast, BT12 6BN, Northern Ireland
    Pediatr Res 67:17-22. 2010
    ..A well-differentiated model of pediatric epithelium has been developed that will be useful for more in vivo like study of the mechanisms at play during asthma...
  7. doi Effects of IL-13 on mucociliary differentiation of pediatric asthmatic bronchial epithelial cells
    Surendran Thavagnanam
    Centre for Infection and Immunity, Queen s University Belfast, Belfast BT12 6BN, Northern Ireland, United Kingdom
    Pediatr Res 69:95-100. 2011
    ..05. IL-13 drives PBEC(N) toward an asthmatic phenotype and worsens the phenotype in PBEC(A) with reduced ciliated cell numbers and increased goblet cells...
  8. pmc Cytopathogenesis of Sendai virus in well-differentiated primary pediatric bronchial epithelial cells
    Remi Villenave
    Queen s University Belfast, Medical Biology Centre, Belfast BT9 7BL, Northern Ireland
    J Virol 84:11718-28. 2010
    ..Alternatively, such robust responses might constitute appropriate normal host responses to viral infection and be a prerequisite for the induction of efficient immune responses...
  9. pmc Differential cytopathogenesis of respiratory syncytial virus prototypic and clinical isolates in primary pediatric bronchial epithelial cells
    Remi Villenave
    Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, Belfast BT9 7BL, Northern Ireland
    Virol J 8:43. 2011
    ..We hypothesized that such strains may be poorly representative of recent clinical isolates in terms of virus/host interactions in primary human bronchial epithelial cells (PBECs)...
  10. doi Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma
    Claire A Butler
    Centre for Infection and Immunity, Queens University Belfast, Level 8, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, Northern Ireland, UK
    Thorax 67:392-8. 2012
    ....
  11. doi Wild-type measles virus infection of primary epithelial cells occurs via the basolateral surface without syncytium formation or release of infectious virus
    Martin Ludlow
    Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen s University of Belfast, Belfast BT9 7BL, UK
    J Gen Virol 91:971-9. 2010
    ..o.i. The low numbers of MV-infected epithelial cells observed in vivo in conjunction with the absence of infectious virus release from infected primary cell cultures suggest that epithelial cells have a peripheral role in MV transmission...
  12. pmc Staphylococcus aureus enterotoxins induce IL-8 secretion by human nasal epithelial cells
    Garrett J O'Brien
    Respiratory Research Group, School of Medicine and Dentistry, Queen s University Belfast, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland, UK
    Respir Res 7:115. 2006
    ..Staphylococcus aureus produces a set of proteins which act both as superantigens and toxins. Although their mode of action as superantigens is well understood, little is known about their effects on airway epithelial cells...