Research Topics
Species | Lorcan P McGarveySummaryAffiliation: Queen's University Belfast Country: UK Publications
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Detail Information
Publications
Psychogenic cough in a schoolboy: evaluation using an ambulatory cough recorderLorcan P A McGarvey
Department of Respiratory Medicine, Belfast City Hospital, Northern Ireland, UK
Pediatr Pulmonol 36:73-5. 2003..Objective cough monitoring may therefore improve the evaluation and management of chronic cough...
General and respiratory health outcomes in adult survivors of bronchopulmonary dysplasia: a systematic reviewAisling Gough
Nursing and Midwifery Research Unit, Queen s University of Belfast, 97 Lisburn Rd, Belfast, BT9 7BL, Northern Ireland
Chest 141:1554-67. 2012..The purpose of this systematic literature review was to examine current empirical research on general and respiratory health outcomes in adult survivors of bronchopulmonary dysplasia (BPD)...
Cause-specific mortality adjudication in the UPLIFT® COPD trial: findings and recommendationsLorcan P McGarvey
Centre for Infection and Immunity, Queen s University Belfast, Belfast BT9 7BL, Northern Ireland, UK
Respir Med 106:515-21. 2012..Future multicentre COPD trials should plan appropriate infrastructure before study initiation to ensure collection and interpretation of fatal events data...
Does idiopathic cough exist?Lorcan P A McGarvey
Department of Medicine, The Queen s University of Belfast, Belfast, Northern Ireland, UK
Lung 186:S78-81. 2008..Almost nothing else is known about this clinical entity and currently no specific therapy exists...
The management of cough: a clinical year in reviewLorcan McGarvey
Respiratory Medicine Research Group, Centre for Infection and Immunity, The Queen s University of Belfast, Grosvenor Road, Belfast, BT12 6BJ, Northern Ireland
Lung 188:S3-8. 2010..While this article reflects a personal commentary of the literature, it is hoped that it will contribute to improving "evidence-based" care for the many individuals burdened with a troublesome cough...
Are there clinical features of a sensitized cough reflex?L McGarvey
Regional Respiratory Centre, Belfast City Hospital, Belfast, N Ireland
Pulm Pharmacol Ther 22:59-64. 2009..Identifying such agents remains a clinical, scientific and pharmacological challenge...
Common causes and current guidelinesL P A McGarvey
Department of Medicine, Queen s University of Belfast, Belfast, UK
Chron Respir Dis 4:215-23. 2007..Such progress will be critical in the search for new and effective treatments for cough...
Patterns of cough in the clinicL P A McGarvey
Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen s University Belfast, Health Sciences Building, 97 Lisburn Road, Belfast BT9 7BL, Ireland
Pulm Pharmacol Ther 24:300-3. 2011..In this article the current knowledge of the clinical patterns of cough is discussed and the potential for new technology to record cough patterns in a meaningful way is considered...
Ascertainment of cause-specific mortality in COPD: operations of the TORCH Clinical Endpoint CommitteeLorcan P McGarvey
The Queen s University of Belfast, Grosvenor Road, Belfast BT12 6BJ, UK
Thorax 62:411-5. 2007..The primary outcome is all-cause mortality. Cause-specific mortality and deaths related to COPD are additional outcome measures, but systematic methods for ascertainment of these outcomes have not previously been described...
Clinical cough and its mechanismsL P A McGarvey
Department of Medicine, The Queen s University of Belfast, Grosvenor Road, Belfast BT12 6BJ, N Ireland, UK
Respir Physiol Neurobiol 152:363-71. 2006....
Idiopathic cough, prevalence and underlying mechanismsL P A McGarvey
Department of Medicine, The Queen s University of Belfast, Grosvenor Road, Belfast BT126BJ, Northern Ireland, UK
Pulm Pharmacol Ther 17:435-9. 2004..This paper seeks to investigate some of the possible causes of idiopathic cough...
Acute and chronic coughL P A McGarvey
Department of Medicine, The Queen s University of Belfast, Grosvenor Road, Belfast BT126BJ, N Ireland, UK
Pulm Pharmacol Ther 17:351-4. 2004..The development of effective treatments for cough remains a challenge and will require co-operation between clinicians, scientists and the pharmaceutical industry...
Cough . 6: Which investigations are most useful in the diagnosis of chronic cough?L P A McGarvey
Department of Medicine, Institute of Clinical Science, The Queen s University of Belfast, Grosvenor Road, Belfast, UK
Thorax 59:342-6. 2004..More precise diagnostic tools and improved therapeutic options are required. Until then, the management of chronic cough will remain a clinical challenge...
Future directions in treating coughLorcan P A McGarvey
Centre for Infection and Immunity, The Queen s University of Belfast, Belfast, Northern Ireland, UK
Otolaryngol Clin North Am 43:199-211, xii. 2010..In addition, the article provides an overview of some of the diagnostic technologies and promising drug targets likely to emerge from current clinical and scientific endeavor...
Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthmaClaire A Butler
Centre for Infection and Immunity, Queens University Belfast, Level 8, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, Northern Ireland, UK
Thorax 67:392-8. 2012....
The utility of fractional exhaled nitric oxide suppression in the identification of nonadherence in difficult asthmaDiarmuid M McNicholl
Centre for Infection and Immunity, Queen s University of Belfast, Level 8, Belfast City Hospital, Lisburn Road, Belfast, Northern Ireland BT9 7AB, UK
Am J Respir Crit Care Med 186:1102-8. 2012..Conclusions: Fe(NO) suppression after DOICS provides an objective test to distinguish adherent from nonadherent patients with difficult asthma. Clinical trial registered with www.clinicaltrials.gov (NCT 01219036)...
The utility of cardiopulmonary exercise testing in difficult asthmaDiarmuid M McNicholl
Centre for Infection and Immunity, Queen s University Belfast, Northern Ireland
Chest 139:1117-23. 2011..Cardiopulmonary exercise testing (CPX) may help identify the mechanism causing these symptoms, allowing appropriate management...
Oesophageal pH monitoring is of limited value in the diagnosis of "reflux-cough"R N Patterson
Dept of Medicine, Queen s University Belfast, Belfast, Northern Ireland, UK
Eur Respir J 24:724-7. 2004..No features on pH monitoring accurately predicted response. Short-term response did not predict long-term response. The precise role for pH monitoring in the assessment of chronic cough remains to be defined...
Cytokine concentrations and neutrophil elastase activity in bronchoalveolar lavage and induced sputum from patients with cystic fibrosis, mild asthma and healthy volunteersL P A McGarvey
Department of Respiratory Medicine, Level 8, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, Northern Ireland, UK
J Cyst Fibros 1:269-75. 2002..The aim of this study was to compare both methods in patients with cystic fibrosis (CF). The possible differences between subjects with CF, mild asthma and healthy volunteers (HV) was also assessed...
Pseudodextrocardia in bronchiectasisM G Kelly
Department of Respiratory Medicine, Belfast City Hospital, Belfast BT9 7AB
Hosp Med 63:304-5. 2002
Increased tachykinin levels in induced sputum from asthmatic and cough patients with acid refluxRobert N Patterson
Department of Medicine, Queen s University Belfast, and Regional Respiratory Centre, Belfast City Hospital, Grosvenor Road, Belfast BT12 6BJ, UK
Thorax 62:491-5. 2007..Acid reflux may aggravate airway disease including asthma and chronic cough. One postulated mechanism concerns a vagally-mediated oesophageal-tracheobronchial reflex with airway sensory nerve activation and tachykinin release...
