H L Halliday

Summary

Affiliation: Queen's University Belfast
Country: UK

Publications

  1. pmc Peer-mentoring for first-time mothers from areas of socio-economic disadvantage: a qualitative study within a randomised controlled trial
    Christine A Murphy
    Royal Group of Hospitals, Belfast, Northern Ireland, 2Division of Public Health Medicine and Primary Care, Queen s University, Belfast, Northern Ireland
    BMC Health Serv Res 8:46. 2008
  2. ncbi request reprint Postnatal steroids and chronic lung disease in the newborn
    Henry L Halliday
    Royal Maternity Hospital and Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    Paediatr Respir Rev 5:S245-8. 2004
  3. ncbi request reprint Use of steroids in the perinatal period
    Henry L Halliday
    Royal Maternity Hospital, and Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    Paediatr Respir Rev 5:S321-7. 2004
  4. ncbi request reprint What interventions facilitate weaning from the ventilator? A review of the evidence from systematic reviews
    Henry L Halliday
    Department of Child Health, Queens, University of Belfast and Regional Neonatal Unit, Royal Maternity Hospital, Belfast, Northern Ireland
    Paediatr Respir Rev 5:S347-52. 2004
  5. doi request reprint Surfactants: past, present and future
    H L Halliday
    Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    J Perinatol 28:S47-56. 2008
  6. doi request reprint Neonatal management and long-term sequelae
    Henry L Halliday
    Perinatal Medicine, Royal Maternity Hospital, and Department of Child Health, Queen s University Belfast, Belfast, Northern Ireland
    Best Pract Res Clin Obstet Gynaecol 23:871-80. 2009
  7. ncbi request reprint Prevention strategies of chronic lung disease
    Henry L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    Pediatr Pulmonol Suppl 26:103-5. 2004
  8. ncbi request reprint Early postnatal dexamethasone and cerebral palsy
    Henry L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Department of Child Health, Queen s University of Belfast, Belfast BT 12 6BB Northern Ireland
    Pediatrics 109:1168-9. 2002
  9. ncbi request reprint The effect of postnatal steroids on growth and development
    H L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Department of Child Health, Queen s University Belfast, Belfast, Northern Ireland
    J Perinat Med 29:281-5. 2001
  10. ncbi request reprint Airway proteins--surfactants
    Henry L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    Pediatr Pulmonol Suppl 26:143-6. 2004

Collaborators

Detail Information

Publications50

  1. pmc Peer-mentoring for first-time mothers from areas of socio-economic disadvantage: a qualitative study within a randomised controlled trial
    Christine A Murphy
    Royal Group of Hospitals, Belfast, Northern Ireland, 2Division of Public Health Medicine and Primary Care, Queen s University, Belfast, Northern Ireland
    BMC Health Serv Res 8:46. 2008
    ..This paper describes the experiences of lay-workers, women and health professionals involved in the trial...
  2. ncbi request reprint Postnatal steroids and chronic lung disease in the newborn
    Henry L Halliday
    Royal Maternity Hospital and Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    Paediatr Respir Rev 5:S245-8. 2004
    ..Corticosteroids, because of their anti- inflammatory actions, have been used to modify the course of CLD. There have been almost 40 randomised controlled trials of postnatal dexamethasone and 12 of inhaled steroids...
  3. ncbi request reprint Use of steroids in the perinatal period
    Henry L Halliday
    Royal Maternity Hospital, and Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    Paediatr Respir Rev 5:S321-7. 2004
    ..Randomised controlled trials have been performed to evaluate the benefits and risks of perinatal corticosteroid therapy...
  4. ncbi request reprint What interventions facilitate weaning from the ventilator? A review of the evidence from systematic reviews
    Henry L Halliday
    Department of Child Health, Queens, University of Belfast and Regional Neonatal Unit, Royal Maternity Hospital, Belfast, Northern Ireland
    Paediatr Respir Rev 5:S347-52. 2004
    ..Shorter ventilation should reduce these risks and a number of interventions have been tested to facilitate earlier extubation...
  5. doi request reprint Surfactants: past, present and future
    H L Halliday
    Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    J Perinatol 28:S47-56. 2008
    ..Nevertheless, surfactant therapy has been a major contribution to care of the preterm newborn during the past 25 years...
  6. doi request reprint Neonatal management and long-term sequelae
    Henry L Halliday
    Perinatal Medicine, Royal Maternity Hospital, and Department of Child Health, Queen s University Belfast, Belfast, Northern Ireland
    Best Pract Res Clin Obstet Gynaecol 23:871-80. 2009
    ..Intrauterine growth restriction is also associated with a five- to seven-fold increased risk of cerebral palsy probably due to chronic placental insufficiency...
  7. ncbi request reprint Prevention strategies of chronic lung disease
    Henry L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    Pediatr Pulmonol Suppl 26:103-5. 2004
  8. ncbi request reprint Early postnatal dexamethasone and cerebral palsy
    Henry L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Department of Child Health, Queen s University of Belfast, Belfast BT 12 6BB Northern Ireland
    Pediatrics 109:1168-9. 2002
  9. ncbi request reprint The effect of postnatal steroids on growth and development
    H L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Department of Child Health, Queen s University Belfast, Belfast, Northern Ireland
    J Perinat Med 29:281-5. 2001
    ..Other non-drug interventions should be used to minimize the risk of chronic lung disease in very preterm infants...
  10. ncbi request reprint Airway proteins--surfactants
    Henry L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Department of Child Health, Queen s University of Belfast, Belfast, Northern Ireland
    Pediatr Pulmonol Suppl 26:143-6. 2004
  11. doi request reprint Useless perinatal therapies
    Henry L Halliday
    Department of Child Health, Queen s University Belfast and Perinatal Medicine, Royal Maternity Hospital, Belfast, UK
    Neonatology 97:358-65. 2010
    ..Even in the modern age, inappropriate therapies have been introduced on the basis of short-term beneficial outcomes without longer-term evaluation. Sometimes we are slow to learn the lessons of the past...
  12. ncbi request reprint Evidence-based neonatal care
    Henry L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Belfast and Department of Child Health, Queen s University of Belfast, Grosvenor Road, Belfast, Northern Ireland BT12 6BB, UK
    Best Pract Res Clin Obstet Gynaecol 19:155-66. 2005
    ..Most of the systematic reviews deal with neonatal care in the developed world, and there are only a few of interest to carers in the developing world...
  13. ncbi request reprint A multicenter, randomized open study of early corticosteroid treatment (OSECT) in preterm infants with respiratory illness: comparison of early and late treatment and of dexamethasone and inhaled budesonide
    H L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Belfast, Northern Ireland
    Pediatrics 107:232-40. 2001
    ..To compare early (<3 days) with late (>15 days) steroid therapy and dexamethasone with inhaled budesonide in very preterm infants at risk of developing chronic lung disease...
  14. ncbi request reprint History of surfactant from 1980
    Henry L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, and Department of Child Health, Queen s University of Belfast, Northern Ireland, UK
    Biol Neonate 87:317-22. 2005
    ..Future studies will focus on widening the indications for surfactant treatment, developing non-invasive means of administration and assessing the role of the newer synthetic surfactants...
  15. ncbi request reprint Recent clinical trials of surfactant treatment for neonates
    Henry L Halliday
    Regional Neonatal Unit, Royal Jubilee Maternity Service, Royal Maternity Hospital and Department of Child Health, Queen s University Belfast, Northern Ireland, UK
    Biol Neonate 89:323-9. 2006
    ..To search for recent clinical trials of neonatal surfactant treatment and report their findings...
  16. pmc Chorioamnionitis increases matrix metalloproteinase-8 concentrations in bronchoalveolar lavage fluid from preterm babies
    A E Curley
    Department of Child Health, Queen s University Belfast, and the Regional Neonatal Unit, Royal Maternity Hospital, Belfast, Northern Ireland
    Arch Dis Child Fetal Neonatal Ed 89:F61-4. 2004
    ..To determine the effects of chorioamnionitis and antenatal corticosteroids on matrix metalloproteinase-8 (MMP-8) concentrations in bronchoalveolar lavage (BAL) fluid from preterm babies in the first week of life...
  17. ncbi request reprint The role of matrix metalloproteinases -9 and -2 in development of neonatal chronic lung disease
    D G Sweet
    Department of Child Health, Queen s University of Belfast, Institute of Clinical Science, Belfast, Northern Ireland, UK
    Acta Paediatr 93:791-6. 2004
    ..We determined factors influencing MMP levels in neonatal bronchoalveolar lavage (BAL) fluid to establish whether an imbalance between MMP and its inhibitor could be implicated in CLD...
  18. ncbi request reprint Clinical trials of postnatal corticosteroids: inhaled and systemic
    H L Halliday
    Department of Child Health, The Queen s University of Belfast and Regional Neonatal Unit, Royal Maternity Hospital, Belfast, Northern Ireland
    Biol Neonate 76:29-40. 1999
    ..Further research is necessary to define the roles of systemic and inhaled steroids in the prevention and treatment of CLD and to allow comparison of benefits to costs...
  19. pmc Study of maternal influences on fetal iron status at term using cord blood transferrin receptors
    D G Sweet
    Department of Child Health, The Queen s University of Belfast and Regional Neonatal Unit, Royal Maternity Hospital, Belfast, UK
    Arch Dis Child Fetal Neonatal Ed 84:F40-3. 2001
    ..To determine effects of maternal iron depletion and smoking on iron status of term babies using serum transferrin receptors (STfR) and their ratio to ferritin (TfR-F index) in cord blood...
  20. ncbi request reprint Oxidative stress and increased type-IV collagenase levels in bronchoalveolar lavage fluid from newborn babies
    B C Schock
    Department of Clinical Biochemistry, Institute of Clinical Science, The Queen's University of Belfast, Belfast BT12 6BJ, Northern Ireland, UK
    Pediatr Res 50:29-33. 2001
    ..Increased oxidative stress may damage the lung by increasing type-IV collagenase activity, causing disruption of the extracellular matrix...
  21. doi request reprint Intra-uterine growth restriction and increased risk of hypertension in adult life: a follow-up study of 50-year-olds
    D Spence
    School of Nursing and Midwifery, Queen s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK
    Public Health 126:561-5. 2012
    ....
  22. ncbi request reprint Postnatal dexamethasone: what is the real cost-benefit ratio?
    H L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Department of Child Health, Queen s University of Belfast, Northern Ireland h halliday qub ac uk
    Acta Paediatr 92:888-9. 2003
    ..CONCLUSION: Further research is needed to determine the lowest dose of corticosteroid that will improve lung function and minimize risks to the developing brain...
  23. ncbi request reprint The present status of exogenous surfactant for the newborn
    A E Curley
    Regional Neonatal Unit, Royal Maternity Hospital, Grosvenor Road, BT12 6BB, Northern Ireland, Belfast, UK
    Early Hum Dev 61:67-83. 2001
    ....
  24. doi request reprint Quantification of Hox and surfactant protein-B transcription during murine lung development
    David G Grier
    Regional Neonatal Unit, Royal Maternity Hospital, Grosvenor Road, Belfast BT12 6BB, UK
    Neonatology 96:50-60. 2009
    ..Hox genes are involved in the lung branching morphogenesis and maturation of respiratory epithelium, but their expression pattern remains to be defined...
  25. pmc Cord blood transferrin receptors to assess fetal iron status
    D G Sweet
    Royal Maternity Hospital, Grosvenor Road, Belfast BT12 6BB, Northern Ireland
    Arch Dis Child Fetal Neonatal Ed 85:F46-8. 2001
    ..To study iron status at different gestational ages using cord blood serum transferrin receptors (STfRs)...
  26. ncbi request reprint Randomized trial of novel tetracaine patch to provide local anaesthesia in neonates undergoing venepuncture
    C P Long
    School of Pharmacy, Queen s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK
    Br J Anaesth 91:514-8. 2003
    ..We assessed a novel tetracaine-based self-adhesive patch in providing controlled local anaesthesia before venepuncture...
  27. doi request reprint A RCT of peer-mentoring for first-time mothers in socially disadvantaged areas (the MOMENTS Study)
    M E Cupples
    Department of General Practice and Primary Care, Queen s University Belfast, Belfast, UK
    Arch Dis Child 96:252-8. 2011
    ..The authors aimed to examine the effect of an innovative tailored peer-mentoring programme, based on perceived needs, for first-time mothers in socio-economically deprived communities...
  28. pmc Does intrauterine growth restriction affect quality of life in adulthood?
    Dale Spence
    Nursing and Midwifery Research Unit, Queen s University Belfast, Belfast, Northern Ireland, UK
    Arch Dis Child 92:700-3. 2007
    ....
  29. pmc HOX genes: seductive science, mysterious mechanisms
    Terence R J Lappin
    Haematology Research Group, Centre for Cancer Research and Cell Biology, Queen s University Belfast, Belfast City Hospital
    Ulster Med J 75:23-31. 2006
    ..Investigation of the role of HOX genes in cancer has led to the concept that oncology may recapitulate ontology, a challenging postulate for experimentalists in view of the functional redundancy implicit in the HOX gene network...
  30. ncbi request reprint Case 4: assessment. Early chronic lung disease
    D G Sweet
    Maternity Hospital, Belfast, Northern Ireland, UK
    Paediatr Respir Rev 3:162, 164-5. 2002
  31. doi request reprint The use of surfactants in 2009
    D G Sweet
    Regional Neonatal Unit, Royal Maternity Hospital, Belfast BT12 6BJ, Northern Ireland, UK
    Arch Dis Child Educ Pract Ed 94:78-83. 2009
    ..Finally, the quest goes on to develop a synthetic product that can match the effects of animal derived natural surfactants and could be produced at lower cost...
  32. ncbi request reprint Which interventions for neonatal respiratory failure are effective?
    H L Halliday
    Regional Neonatal Unit, Royal Maternity Hospital, Belfast, BT12 6BB, Northern Ireland
    Croat Med J 39:165-70. 1998
    ..To review the evidence from clinical trials of various interventions to treat and prevent respiratory failure in the neonate and to determine which interventions are effective and which require further study...
  33. ncbi request reprint Airway remodelling in chronic lung disease of prematurity
    David G Sweet
    Perinatal Room, Royal Maternity Hospital, Grosvenor Road, Belfast BT12 6BB, Northern Ireland, UK
    Paediatr Respir Rev 3:140-6. 2002
    ..This so called "new chronic lung disease" resulting from airways remodelling and arrested lung development is characterised pathologically by fewer, larger alveoli and less pulmonary fibrosis than previously described...
  34. ncbi request reprint Neurodevelopmental and respiratory follow-up results at 7 years for children from the United Kingdom and Ireland enrolled in a randomized trial of early and late postnatal corticosteroid treatment, systemic and inhaled (the Open Study of Early Corticoster
    Trevor T Wilson
    Regional Neonatal Unit, Royal Maternity Hospital, Belfast BT12 6BB, Northern Ireland
    Pediatrics 117:2196-205. 2006
    ....
  35. ncbi request reprint Modeling and remodeling of the lung in neonatal chronic lung disease: implications for therapy
    David G Sweet
    Regional Neonatal Unit, Royal Maternity Hospital, Belfast, Northern Ireland
    Treat Respir Med 4:347-59. 2005
    ....
  36. ncbi request reprint Corticosteroids in the prevention and management of bronchopulmonary dysplasia
    David G Grier
    Regional Neonatal Unit, Royal Maternity Hospital, BT12 6BB, Northern Ireland, Belfast, UK
    Semin Neonatol 8:83-91. 2003
    ..This review attempts to provide evidence-based guidelines for postnatal steroid therapy in the management of chronic lung disease...
  37. ncbi request reprint Effects of glucocorticoids on fetal and neonatal lung development
    David G Grier
    Department of Child Health, Queen s University Belfast, Northern Ireland, UK
    Treat Respir Med 3:295-306. 2004
    ....
  38. pmc Type I collagenases in bronchoalveolar lavage fluid from preterm babies at risk of developing chronic lung disease
    D G Sweet
    Department of Child Health, The Queen s University of Belfast and Regional Neonatal Unit, Royal Maternity Hospital, Belfast, Northern Ireland
    Arch Dis Child Fetal Neonatal Ed 84:F168-71. 2001
    ..To assess whether increased collagenolysis precedes severe chronic lung disease (CLD)...
  39. ncbi request reprint Lyso-phosphatidylcholine and outcome of preterm babies with respiratory distress syndrome treated with surfactant
    M M O'Hare
    Department of Child Health, Queen s University of Belfast, Ireland, UK
    Early Hum Dev 49:135-41. 1997
    ....
  40. ncbi request reprint Interventions to prevent hypothermia at birth in preterm and/or low birthweight infants
    Emma M McCall
    School of Medicine, Dentistry and Biomedical Sciences, Queen s University Belfast, Microbiology Building, Grosvenor Road, Belfast, Northern Ireland, UK, BT12 6BN
    Cochrane Database Syst Rev 3:CD004210. 2010
    ..However, the small numbers of infants and studies and the absence of long-term follow-up mean that firm recommendations for clinical practice cannot be given...
  41. ncbi request reprint Chorioamnionitis and increased neonatal lung lavage fluid matrix metalloproteinase-9 levels: implications for antenatal origins of chronic lung disease
    Anna E Curley
    Department of Child Health, Queen s University of Belfast, Institute of Clinical Science, Belfast, Northern Ireland
    Am J Obstet Gynecol 188:871-5. 2003
    ..We studied the effects of chorioamnionitis and antenatal corticosteroids on bronchoalveolar lavage (BAL) fluid levels of MMP-9, and its inhibitor, TIMP-1 in preterm infants...
  42. ncbi request reprint Gastro-intestinal complications following neonatal cardiac catheterisation
    D G Sweet
    Royal Maternity Hospital, Belfast, Northern Ireland
    J Perinat Med 26:196-200. 1998
    ..We examined a cohort of infants with congenital cyanotic heart disease in order to assess the role of cardiac catheterisation in the pathogenesis of NEC...
  43. pmc Intravenous indometacin in preterm infants with symptomatic patent ductus arteriosus. A population pharmacokinetic study
    J M Smyth
    Clinical and Practice Research Group, School of Pharmacy, Queen s University, Belfast, UK
    Br J Clin Pharmacol 58:249-58. 2004
    ..To characterize the population pharmacokinetics of indometacin in preterm infants with symptomatic patent ductus arteriosus and to investigate the influence of various factors on the response to treatment...
  44. ncbi request reprint Management of bronchopulmonary dysplasia in infants: guidelines for corticosteroid use
    David G Grier
    Department of Child Health, Queen s University, Belfast, Northern Ireland, UK
    Drugs 65:15-29. 2005
    ..Further randomised trials of low-dose corticosteroids given after the first week of life are warranted and should assess both short- and long-term outcomes...
  45. doi request reprint Maternal betamethasone and chorioamnionitis induce different collagenases during lung maturation in fetal sheep
    David G Sweet
    Department of Child Health, The Queen s University of Belfast, UK
    Neonatology 94:79-86. 2008
    ..The effectors of this antenatally-induced lung maturation are not understood. Matrix metalloproteinases (MMPs) 2 and 9 are type-IV collagenases that can degrade alveolar basement membranes...
  46. doi request reprint European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants - 2010 update
    David G Sweet
    Regional Neonatal Unit, Royal Maternity Hospital, Belfast, UK
    Neonatology 97:402-17. 2010
    ....
  47. ncbi request reprint Neonatology. Preface
    Dominique Haumont
    Neonatology 93:282-3. 2008
  48. ncbi request reprint Impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: effect modification by risk for chronic lung disease
    Lex W Doyle
    Division of Paediatrics, Royal Women s Hospital, 132 Grattan St, Carlton 3053, Australia
    Pediatrics 115:655-61. 2005
    ..The objective of this study was to determine the effect of systemic postnatal corticosteroid treatment on death and CP and to assess any modification of effect arising from risk for CLD...
  49. ncbi request reprint Lucinactant versus poractant-alpha in premature lambs
    Henry L Halliday
    Pediatrics 117:2324-5; author reply 2325. 2006