O M El-Agnaf

Summary

Affiliation: Queen's University Belfast
Country: UK

Publications

  1. ncbi request reprint Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease
    O M El-Agnaf
    Centre for Peptide and Protein Engineering, School of Biology and Biochemistry, Queen s University Belfast, UK
    FEBS Lett 440:67-70. 1998
  2. ncbi request reprint Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments
    O M El-Agnaf
    Centre for Peptide and Protein Engineering, School of Biology and Biochemistry, Queen s University Belfast, UK
    FEBS Lett 440:71-5. 1998

Detail Information

Publications2

  1. ncbi request reprint Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease
    O M El-Agnaf
    Centre for Peptide and Protein Engineering, School of Biology and Biochemistry, Queen s University Belfast, UK
    FEBS Lett 440:67-70. 1998
    ..These findings suggest that accumulation of alpha-syn as insoluble deposits of amyloid may play a major role in the pathogenesis of these neurodegenerative diseases...
  2. ncbi request reprint Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments
    O M El-Agnaf
    Centre for Peptide and Protein Engineering, School of Biology and Biochemistry, Queen s University Belfast, UK
    FEBS Lett 440:71-5. 1998
    ..These findings indicate that accumulation of alpha-syn and its degradation products may play a major role in the development of the pathogenesis of these neurodegenerative diseases...