Research Topics
| Chris R CardwellSummaryAffiliation: Queen's University Belfast Country: UK Publications
| Collaborators
|
Detail Information
Publications
Breast-Feeding and Childhood-Onset Type 1 Diabetes: A pooled analysis of individual participant data from 43 observational studiesChris R Cardwell
Corresponding author Chris R Cardwell
Diabetes Care 35:2215-25. 2012..However, these findings are difficult to interpret because of the marked variation in effect and possible biases (particularly recall bias) inherent in the included studies...- Exposure to oral bisphosphonates and risk of cancerChris R Cardwell
Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen s University Belfast, United Kingdom
Int J Cancer 131:E717-25. 2012..Although reductions in breast and colorectal cancer incidence were observed in bisphosphonate users it is unclear, particularly for breast cancer, to what extent confounding by low bone density may explain the association... - Interbirth interval is associated with childhood type 1 diabetes riskChris R Cardwell
Centre for Public Health, Queen s University Belfast, Belfast, UK
Diabetes 61:702-7. 2012..93]). Adjustments for various potential confounders little altered this estimate. In conclusion, there was evidence of a 20% reduction in the risk of childhood diabetes in children born to mothers after interbirth intervals <3 years... 
A meta-analysis of the association between childhood type 1 diabetes and atopic diseaseChris R Cardwell
Department of Epidemiology and Public Health, Queen s University of Belfast, Belfast, Northern Ireland, UK
Diabetes Care 26:2568-74. 2003..To review the published literature and perform a meta-analysis summarizing the evidence in support of an inverse association between type 1 diabetes and the atopic disorders: asthma, eczema, and allergic rhinitis in children...
Birth order and childhood type 1 diabetes risk: a pooled analysis of 31 observational studiesChris R Cardwell
Centre for Public Health, Queen s University Belfast, Belfast, UK
Int J Epidemiol 40:363-74. 2011..We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous studies...- Exposure to oral bisphosphonates and risk of esophageal cancerChris R Cardwell
Centre for Public Health, Queen s University Belfast, Grosvenor Rd, Belfast BT12 6BJ, United Kingdom
JAMA 304:657-63. 2010..Esophagitis is a known adverse effect of bisphosphonate use, and recent reports suggest a link between bisphosphonate use and esophageal cancer, but this has not been robustly investigated... - Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient dataC R Cardwell
Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen s University Belfast, Grosvenor Road, Belfast BT12 6BJ, UK
Diabetologia 53:641-51. 2010..We investigated whether children who are heavier at birth have an increased risk of type 1 diabetes... - Maternal age at birth and childhood type 1 diabetes: a pooled analysis of 30 observational studiesChris R Cardwell
Centre for Public Health, Queen s University Belfast, Belfast, UK
Diabetes 59:486-94. 2010..The aim if the study was to investigate whether children born to older mothers have an increased risk of type 1 diabetes by performing a pooled analysis of previous studies using individual patient data to adjust for recognized confounders... - Infections in early life and childhood leukaemia risk: a UK case-control study of general practitioner recordsC R Cardwell
Department of Epidemiology and Public Health, School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
Br J Cancer 99:1529-33. 2008..05, 95%CI 0.64-1.74; P=0.84). Our study provides no support for the Greaves hypothesis, which proposes that reduced or delayed exposure to infections in early life increases the risk of childhood ALL... - Atopy, home environment and the risk of childhood-onset type 1 diabetes: a population-based case-control studyChris R Cardwell
Department of Epidemiology and Public Health, School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
Pediatr Diabetes 9:191-6. 2008..The marked increases in the incidence of type 1 diabetes in recent decades strongly suggest the role of environmental influences. These environmental influences remain largely unknown... - Tonsillectomy and adenoidectomy are not associated with an altered risk of childhood-onset type 1 diabetesChris R Cardwell
Epidemiology Research Group, School of Medicine and Dentistry, The Queen's University of Belfast, Grosvenor Road, Belfast BT12 6BJ, UK
Diabetes Care 30:2564-5. 2007 - Parental age at delivery, birth order, birth weight and gestational age are associated with the risk of childhood Type 1 diabetes: a UK regional retrospective cohort studyC R Cardwell
Department of Epidemiology and Public Health, The Queen s University of Belfast, Belfast, UK
Diabet Med 22:200-6. 2005..To investigate perinatal risk factors for childhood Type 1 diabetes in a UK population cohort... - Diabetes care provision and glycaemic control in Northern Ireland: a UK regional auditC R Cardwell
Department of Epidemiology and Public Health, The Queen s University of Belfast, UK
Arch Dis Child 90:468-73. 2005..To assess the care received, compared to national guidelines, and to investigate factors associated with glycaemic control in children and adolescents with type 1 diabetes attending clinics in Northern Ireland... - Higher incidence of childhood-onset type 1 diabetes mellitus in remote areas: a UK regional small-area analysisC R Cardwell
School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
Diabetologia 49:2074-7. 2006..We investigated the association between the incidence of type 1 diabetes mellitus and remoteness (a proxy measure for exposure to infections) using recently developed techniques for statistical analysis of small-area data... - Secular trends, disease maps and ecological analyses of the incidence of childhood onset Type 1 diabetes in Northern Ireland, 1989-2003C R Cardwell
School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
Diabet Med 24:289-95. 2007..To highlight geographical variations in the incidence of Type 1 diabetes by producing disease maps and to compare incidence rates by relevant area characteristics... - Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studiesC R Cardwell
Department of Epidemiology and Public Health, School of Medicine and Dentistry, Queen s University Belfast, Grosvenor Road, Belfast, BT12 6BJ, UK
Diabetologia 51:726-35. 2008.... - Glycemic index, glycemic load, and risk of digestive tract neoplasms: a systematic review and meta-analysisHelen G Mulholland
Cancer Epidemiology and Prevention Research Group, Centre for Clinical and Population Sciences, Queen s University Belfast, Mulhouse Building, Royal Victoria Hospital Site, Belfast, Northern Ireland
Am J Clin Nutr 89:568-76. 2009..Habitual consumption of diets with a high glycemic index (GI) and a high glycemic load (GL) may influence cancer risk via hyperinsulinemia and the insulin-like growth factor axis... - Psychosocial interventions to improve quality of life and emotional wellbeing for recently diagnosed cancer patientsKaren Galway
School of Nursing andMidwifery, Queen sUniversity Belfast, Belfast, UK
Cochrane Database Syst Rev 11:CD007064. 2012..A cancer diagnosis may lead to significant psychological distress in up to 75% of cases. There is a lack of clarity about the most effective ways to address this psychological distress... - Dietary patterns and bone mineral status in young adults: the Northern Ireland Young Hearts ProjectClaire R Whittle
School of Medicine, Dentistry and Biomedical Sciences, Centre for Public Health, Queen s University Belfast, Grosvenor Road, Belfast BT12 6BJ, UK
Br J Nutr 108:1494-504. 2012..In conclusion, adherence to a 'Nuts and Meat' dietary pattern may be associated with greater BMS in young women and a 'Refined' dietary pattern may be detrimental for bone health in young men... - Can physical activity modulate pancreatic cancer risk? a systematic review and meta-analysisMichael A O'Rorke
Cancer Epidemiology Health Services Research Group, Centre for Public Health, Queen s University Belfast, Belfast, Northern Ireland, United Kingdom
Int J Cancer 126:2957-68. 2010..Despite indications of an inverse relationship with higher levels of work and total activity, there was little evidence of such associations with recreational and other activity exposures... - The appropriateness of red blood cell use and the extent of overtransfusion: right decision? Right amount?Paul J Barr
Centre for Excellence in Public Health, Queens University Belfast, the Clinical Research Support Centre, Royal Hospitals, Belfast, Northern Ireland
Transfusion 51:1684-94. 2011..This study aimed to ascertain the levels of inappropriate practice and factors associated with it... - Protocolized vs. non-protocolized weaning for reducing the duration of mechanical ventilation in critically ill adult patients: Cochrane review protocolBronagh Blackwood
Nursing and Midwifery Research Unit, School of Nursing and Midwifery, Queen s University Belfast, UK
J Adv Nurs 65:957-64. 2009.... - Dietary glycaemic index, glycaemic load and breast cancer risk: a systematic review and meta-analysisH G Mulholland
Cancer Epidemiology and Prevention Research Group, Centre for Clinical and Population Sciences, Queens University Belfast, Royal Victoria Hospital Site, Grosvenor Road, Belfast, BT12 6BJ, UK
Br J Cancer 99:1170-5. 2008..Pooled cohort study results indicated no association between postmenopausal risk and GL intake (RR 1.03, 95% CI 0.94-1.12). Our findings do not provide strong support of an association between dietary GI and GL and breast cancer risk... - Is hyperfiltration associated with the future risk of developing diabetic nephropathy? A meta-analysisG M Magee
Regional Centre for Diabetes and Endocrinology, Level 1, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, UK
Diabetologia 52:691-7. 2009..We performed a systematic review and meta-analysis of observational studies that compared the risk of developing diabetic nephropathy in patients with and without glomerular hyperfiltration and also explored the impact of baseline GFR... - Dietary glycaemic index, glycaemic load and endometrial and ovarian cancer risk: a systematic review and meta-analysisH G Mulholland
Cancer Epidemiology and Prevention Research Group, Centre for Clinical and Population Sciences, Queens University Belfast, Mulhouse Building, Royal Victoria Hospital Site, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland
Br J Cancer 99:434-41. 2008..A high GL, but not a high GI, diet is positively associated with the risk of endometrial cancer, particularly among obese women... - Identifying additional patients with diabetic nephropathy using the UK primary care initiativeG M Magee
Regional Centre for Diabetes and Endocrinology, Royal Victoria Hospital, Belfast, Co Antrim, UK
Diabet Med 27:1372-8. 2010.... - Dietary patterns and breast cancer risk: a systematic review and meta-analysisSarah F Brennan
Nutrition and Metabolism Group, Centre for Public Health, Queen s University Belfast, Royal Victoria Hospital, Belfast, United Kingdom
Am J Clin Nutr 91:1294-302. 2010..Dietary patterns, which represent whole-diet and possible food and nutrient interactions, have been linked to the risk of various cancers. However, the associations of these dietary patterns with breast cancer remain unclear... - The effect of androgen deprivation therapy on body composition in men with prostate cancer: systematic review and meta-analysisFarhana Haseen
Centre for Public Health, Queen s University Belfast, Belfast, Northern Ireland, UK
J Cancer Surviv 4:128-39. 2010..Limited information exists regarding the rate and extent of these changes. This systematic review was conducted to determine the effects of ADT on body composition in prostate cancer patients... - No association between routinely recorded infections in early life and subsequent risk of childhood-onset Type 1 diabetes: a matched case-control study using the UK General Practice Research DatabaseC R Cardwell
School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
Diabet Med 25:261-7. 2008..To determine whether children with infections in early life (recorded routinely in general practice) have a reduced risk of Type 1 diabetes, as would be expected from the hygiene hypothesis... - Thalidomide for managing cancer cachexiaJoanne Reid
Nursing and Midwifery Research Unit, School of Nursing, Queen s University Belfast, Belfast, UK
Cochrane Database Syst Rev 4:CD008664. 2012..Preliminary studies of thalidomide have demonstrated encouraging results... - Neonatal jaundice is associated with a small increase in the risk of childhood type 1 diabetes: a meta-analysis of observational studiesMaria B McNamee
Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, UK
Acta Diabetol 49:83-7. 2012..Jaundice caused by blood group incompatibility or requiring phototherapy may be associated with a greater increase in type 1 diabetes risk and deserves further study... - Maternal body mass index and risk of testicular cancer in male offspring: a systematic review and meta-analysisShama S Alam
Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen s University Belfast, Northern Ireland, United Kingdom
Cancer Epidemiol 34:509-15. 2010..This systematic review and meta-analysis investigated the nature of this association... - A systematic review of population based epidemiological studies in Myasthenia GravisAisling S Carr
Department of Neurology, Royal Victoria Hospital, Belfast, Northern Ireland, UK
BMC Neurol 10:46. 2010..To synthesize data on incidence rate (IR), prevalence rate (PR) and mortality rate (MR) of the condition and investigate the influence of environmental and technical factors on any trends or variation observed... - A meta-analysis of the association between Caesarean section and childhood asthmaS Thavagnanam
Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland
Clin Exp Allergy 38:629-33. 2008..The results of previous studies that have investigated the association between Caesarean section and asthma have been conflicting...