Chris R Cardwell

Summary

Affiliation: Queen's University Belfast
Country: UK

Publications

  1. ncbi request reprint Low-dose aspirin use after diagnosis of colorectal cancer does not increase survival: a case-control analysis of a population-based cohort
    Chris R Cardwell
    Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen s University Belfast, Belfast, Northern Ireland Electronic address
    Gastroenterology 146:700-708.e2. 2014
  2. doi request reprint Drugs affecting the renin-angiotensin system and survival from cancer: a population based study of breast, colorectal and prostate cancer patient cohorts
    Chris R Cardwell
    Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen s University Belfast, Belfast, Northern Ireland
    BMC Med 12:28. 2014
  3. doi request reprint Low-dose aspirin and survival in men with prostate cancer: a study using the UK Clinical Practice Research Datalink
    Chris R Cardwell
    Centre for Public Health, Queen s University Belfast, Belfast, BT12 6BA, Northern Ireland, UK
    Cancer Causes Control 25:33-43. 2014
  4. pmc Breast-feeding and childhood-onset type 1 diabetes: a pooled analysis of individual participant data from 43 observational studies
    Chris R Cardwell
    School of Medicine and Dentistry, Queen s University Belfast, Belfast, UK
    Diabetes Care 35:2215-25. 2012
  5. pmc Exposure to oral bisphosphonates and risk of cancer
    Chris R Cardwell
    Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen s University Belfast, United Kingdom
    Int J Cancer 131:E717-25. 2012
  6. pmc Interbirth interval is associated with childhood type 1 diabetes risk
    Chris R Cardwell
    Centre for Public Health, Queen s University Belfast, Belfast, UK
    Diabetes 61:702-7. 2012
  7. pmc Infections in early life and childhood leukaemia risk: a UK case-control study of general practitioner records
    C R Cardwell
    Department of Epidemiology and Public Health, School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
    Br J Cancer 99:1529-33. 2008
  8. pmc Maternal age at birth and childhood type 1 diabetes: a pooled analysis of 30 observational studies
    Chris R Cardwell
    Centre for Public Health, Queen s University Belfast, Belfast, UK
    Diabetes 59:486-94. 2010
  9. doi request reprint Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient data
    C R Cardwell
    Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen s University Belfast, Grosvenor Road, Belfast BT12 6BJ, UK
    Diabetologia 53:641-51. 2010
  10. pmc Exposure to oral bisphosphonates and risk of esophageal cancer
    Chris R Cardwell
    Centre for Public Health, Queen s University Belfast, Grosvenor Rd, Belfast BT12 6BJ, United Kingdom
    JAMA 304:657-63. 2010

Detail Information

Publications43

  1. ncbi request reprint Low-dose aspirin use after diagnosis of colorectal cancer does not increase survival: a case-control analysis of a population-based cohort
    Chris R Cardwell
    Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen s University Belfast, Belfast, Northern Ireland Electronic address
    Gastroenterology 146:700-708.e2. 2014
    ..We investigated survival times of patients who begin taking low-dose aspirin after a diagnosis of colorectal cancer in a large population-based cohort study...
  2. doi request reprint Drugs affecting the renin-angiotensin system and survival from cancer: a population based study of breast, colorectal and prostate cancer patient cohorts
    Chris R Cardwell
    Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen s University Belfast, Belfast, Northern Ireland
    BMC Med 12:28. 2014
    ..We investigated whether ACEI or ARB use after breast, colorectal or prostate cancer diagnosis was associated with increased risk of cancer-specific mortality...
  3. doi request reprint Low-dose aspirin and survival in men with prostate cancer: a study using the UK Clinical Practice Research Datalink
    Chris R Cardwell
    Centre for Public Health, Queen s University Belfast, Belfast, BT12 6BA, Northern Ireland, UK
    Cancer Causes Control 25:33-43. 2014
    ..Aspirin use is associated with reduced risk of, and death from, prostate cancer. Our aim was to determine whether low-dose aspirin use after a prostate cancer diagnosis was associated with reduced prostate cancer-specific mortality...
  4. pmc Breast-feeding and childhood-onset type 1 diabetes: a pooled analysis of individual participant data from 43 observational studies
    Chris R Cardwell
    School of Medicine and Dentistry, Queen s University Belfast, Belfast, UK
    Diabetes Care 35:2215-25. 2012
    ..To investigate if there is a reduced risk of type 1 diabetes in children breastfed or exclusively breastfed by performing a pooled analysis with adjustment for recognized confounders...
  5. pmc Exposure to oral bisphosphonates and risk of cancer
    Chris R Cardwell
    Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen s University Belfast, United Kingdom
    Int J Cancer 131:E717-25. 2012
    ..Although reductions in breast and colorectal cancer incidence were observed in bisphosphonate users it is unclear, particularly for breast cancer, to what extent confounding by low bone density may explain the association...
  6. pmc Interbirth interval is associated with childhood type 1 diabetes risk
    Chris R Cardwell
    Centre for Public Health, Queen s University Belfast, Belfast, UK
    Diabetes 61:702-7. 2012
    ..93]). Adjustments for various potential confounders little altered this estimate. In conclusion, there was evidence of a 20% reduction in the risk of childhood diabetes in children born to mothers after interbirth intervals <3 years...
  7. pmc Infections in early life and childhood leukaemia risk: a UK case-control study of general practitioner records
    C R Cardwell
    Department of Epidemiology and Public Health, School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
    Br J Cancer 99:1529-33. 2008
    ..05, 95%CI 0.64-1.74; P=0.84). Our study provides no support for the Greaves hypothesis, which proposes that reduced or delayed exposure to infections in early life increases the risk of childhood ALL...
  8. pmc Maternal age at birth and childhood type 1 diabetes: a pooled analysis of 30 observational studies
    Chris R Cardwell
    Centre for Public Health, Queen s University Belfast, Belfast, UK
    Diabetes 59:486-94. 2010
    ..The aim if the study was to investigate whether children born to older mothers have an increased risk of type 1 diabetes by performing a pooled analysis of previous studies using individual patient data to adjust for recognized confounders...
  9. doi request reprint Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient data
    C R Cardwell
    Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen s University Belfast, Grosvenor Road, Belfast BT12 6BJ, UK
    Diabetologia 53:641-51. 2010
    ..We investigated whether children who are heavier at birth have an increased risk of type 1 diabetes...
  10. pmc Exposure to oral bisphosphonates and risk of esophageal cancer
    Chris R Cardwell
    Centre for Public Health, Queen s University Belfast, Grosvenor Rd, Belfast BT12 6BJ, United Kingdom
    JAMA 304:657-63. 2010
    ..Esophagitis is a known adverse effect of bisphosphonate use, and recent reports suggest a link between bisphosphonate use and esophageal cancer, but this has not been robustly investigated...
  11. ncbi request reprint A meta-analysis of the association between childhood type 1 diabetes and atopic disease
    Chris R Cardwell
    Department of Epidemiology and Public Health, Queen s University of Belfast, Belfast, Northern Ireland, UK
    Diabetes Care 26:2568-74. 2003
    ..To review the published literature and perform a meta-analysis summarizing the evidence in support of an inverse association between type 1 diabetes and the atopic disorders: asthma, eczema, and allergic rhinitis in children...
  12. doi request reprint Birth order and childhood type 1 diabetes risk: a pooled analysis of 31 observational studies
    Chris R Cardwell
    Centre for Public Health, Queen s University Belfast, Belfast, UK
    Int J Epidemiol 40:363-74. 2011
    ..We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous studies...
  13. ncbi request reprint Parental age at delivery, birth order, birth weight and gestational age are associated with the risk of childhood Type 1 diabetes: a UK regional retrospective cohort study
    C R Cardwell
    Department of Epidemiology and Public Health, The Queen s University of Belfast, Belfast, UK
    Diabet Med 22:200-6. 2005
    ..To investigate perinatal risk factors for childhood Type 1 diabetes in a UK population cohort...
  14. pmc Diabetes care provision and glycaemic control in Northern Ireland: a UK regional audit
    C R Cardwell
    Department of Epidemiology and Public Health, The Queen s University of Belfast, UK
    Arch Dis Child 90:468-73. 2005
    ..To assess the care received, compared to national guidelines, and to investigate factors associated with glycaemic control in children and adolescents with type 1 diabetes attending clinics in Northern Ireland...
  15. ncbi request reprint Higher incidence of childhood-onset type 1 diabetes mellitus in remote areas: a UK regional small-area analysis
    C R Cardwell
    School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
    Diabetologia 49:2074-7. 2006
    ..We investigated the association between the incidence of type 1 diabetes mellitus and remoteness (a proxy measure for exposure to infections) using recently developed techniques for statistical analysis of small-area data...
  16. ncbi request reprint Secular trends, disease maps and ecological analyses of the incidence of childhood onset Type 1 diabetes in Northern Ireland, 1989-2003
    C R Cardwell
    School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
    Diabet Med 24:289-95. 2007
    ..To highlight geographical variations in the incidence of Type 1 diabetes by producing disease maps and to compare incidence rates by relevant area characteristics...
  17. ncbi request reprint Tonsillectomy and adenoidectomy are not associated with an altered risk of childhood-onset type 1 diabetes
    Chris R Cardwell
    Epidemiology Research Group, School of Medicine and Dentistry, The Queen s University of Belfast, Grosvenor Road, Belfast BT12 6BJ, UK
    Diabetes Care 30:2564-5. 2007
  18. doi request reprint Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies
    C R Cardwell
    Department of Epidemiology and Public Health, School of Medicine and Dentistry, Queen s University Belfast, Grosvenor Road, Belfast, BT12 6BJ, UK
    Diabetologia 51:726-35. 2008
    ....
  19. ncbi request reprint Atopy, home environment and the risk of childhood-onset type 1 diabetes: a population-based case-control study
    Chris R Cardwell
    Department of Epidemiology and Public Health, School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
    Pediatr Diabetes 9:191-6. 2008
    ..The marked increases in the incidence of type 1 diabetes in recent decades strongly suggest the role of environmental influences. These environmental influences remain largely unknown...
  20. doi request reprint Glycemic index, glycemic load, and risk of digestive tract neoplasms: a systematic review and meta-analysis
    Helen G Mulholland
    Cancer Epidemiology and Prevention Research Group, Centre for Clinical and Population Sciences, Queen s University Belfast, Mulhouse Building, Royal Victoria Hospital Site, Belfast, Northern Ireland
    Am J Clin Nutr 89:568-76. 2009
    ..Habitual consumption of diets with a high glycemic index (GI) and a high glycemic load (GL) may influence cancer risk via hyperinsulinemia and the insulin-like growth factor axis...
  21. doi request reprint Multidimensional rehabilitation programmes for adult cancer survivors
    David A Scott
    Centre for Health Improvement, Queen s University Belfast, Belfast, UK
    Cochrane Database Syst Rev 3:CD007730. 2013
    ..MDRPs comprise a physical component and a psychosocial component. Studies of the effectiveness of these programmes have not been reviewed and synthesised...
  22. doi request reprint The effect of androgen deprivation therapy on body composition in men with prostate cancer: systematic review and meta-analysis
    Farhana Haseen
    Centre for Public Health, Queen s University Belfast, Belfast, Northern Ireland, UK
    J Cancer Surviv 4:128-39. 2010
    ..Limited information exists regarding the rate and extent of these changes. This systematic review was conducted to determine the effects of ADT on body composition in prostate cancer patients...
  23. doi request reprint Dietary fiber and the risk of precancerous lesions and cancer of the esophagus: a systematic review and meta-analysis
    Helen G Coleman
    Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen s University Belfast, Belfast, Northern Ireland
    Nutr Rev 71:474-82. 2013
    ..31-1.20). Dietary fiber is associated with protective effects against esophageal carcinogenesis, most notably esophageal adenocarcinoma. Potential methods of action include modification of gastroesophageal reflux and/or weight control. ..
  24. ncbi request reprint PTGS2 (Cyclooxygenase-2) expression and survival among colorectal cancer patients: a systematic review
    Andrew T Kunzmann
    Centre of Excellence for Public Health North Ireland, Queen s University Belfast, Belfast, Northern Ireland
    Cancer Epidemiol Biomarkers Prev 22:1490-7. 2013
    ..However, results to date have been mixed...
  25. ncbi request reprint Beta-blocker usage and prostate cancer survival: A nested case-control study in the UK Clinical Practice Research Datalink cohort
    Chris R Cardwell
    Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen s University Belfast, Northern Ireland, UK
    Cancer Epidemiol 38:279-85. 2014
    ..Conclusions: Beta-blocker usage after diagnosis was not associated with cancer-specific or all-cause mortality in prostate cancer patients in this large UK study...
  26. doi request reprint Psychosocial interventions to improve quality of life and emotional wellbeing for recently diagnosed cancer patients
    Karen Galway
    School of Nursing andMidwifery, Queen sUniversity Belfast, Belfast, UK
    Cochrane Database Syst Rev 11:CD007064. 2012
    ..A cancer diagnosis may lead to significant psychological distress in up to 75% of cases. There is a lack of clarity about the most effective ways to address this psychological distress...
  27. doi request reprint Dietary patterns and bone mineral status in young adults: the Northern Ireland Young Hearts Project
    Claire R Whittle
    School of Medicine, Dentistry and Biomedical Sciences, Centre for Public Health, Queen s University Belfast, Grosvenor Road, Belfast BT12 6BJ, UK
    Br J Nutr 108:1494-504. 2012
    ..In conclusion, adherence to a 'Nuts and Meat' dietary pattern may be associated with greater BMS in young women and a 'Refined' dietary pattern may be detrimental for bone health in young men...
  28. doi request reprint Can physical activity modulate pancreatic cancer risk? a systematic review and meta-analysis
    Michael A O'Rorke
    Cancer Epidemiology Health Services Research Group, Centre for Public Health, Queen s University Belfast, Belfast, Northern Ireland, United Kingdom
    Int J Cancer 126:2957-68. 2010
    ..Despite indications of an inverse relationship with higher levels of work and total activity, there was little evidence of such associations with recreational and other activity exposures...
  29. ncbi request reprint Protocolized vs. non-protocolized weaning for reducing the duration of mechanical ventilation in critically ill adult patients: Cochrane review protocol
    Bronagh Blackwood
    Nursing and Midwifery Research Unit, School of Nursing and Midwifery, Queen s University Belfast, UK
    J Adv Nurs 65:957-64. 2009
    ....
  30. doi request reprint The appropriateness of red blood cell use and the extent of overtransfusion: right decision? Right amount?
    Paul J Barr
    Centre for Excellence in Public Health, Queens University Belfast, the Clinical Research Support Centre, Royal Hospitals, Belfast, Northern Ireland
    Transfusion 51:1684-94. 2011
    ..This study aimed to ascertain the levels of inappropriate practice and factors associated with it...
  31. pmc Dietary glycaemic index, glycaemic load and endometrial and ovarian cancer risk: a systematic review and meta-analysis
    H G Mulholland
    Cancer Epidemiology and Prevention Research Group, Centre for Clinical and Population Sciences, Queens University Belfast, Mulhouse Building, Royal Victoria Hospital Site, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland
    Br J Cancer 99:434-41. 2008
    ..A high GL, but not a high GI, diet is positively associated with the risk of endometrial cancer, particularly among obese women...
  32. pmc Dietary glycaemic index, glycaemic load and breast cancer risk: a systematic review and meta-analysis
    H G Mulholland
    Cancer Epidemiology and Prevention Research Group, Centre for Clinical and Population Sciences, Queens University Belfast, Royal Victoria Hospital Site, Grosvenor Road, Belfast, BT12 6BJ, UK
    Br J Cancer 99:1170-5. 2008
    ..Pooled cohort study results indicated no association between postmenopausal risk and GL intake (RR 1.03, 95% CI 0.94-1.12). Our findings do not provide strong support of an association between dietary GI and GL and breast cancer risk...
  33. ncbi request reprint Is hyperfiltration associated with the future risk of developing diabetic nephropathy? A meta-analysis
    G M Magee
    Regional Centre for Diabetes and Endocrinology, Level 1, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, UK
    Diabetologia 52:691-7. 2009
    ..We performed a systematic review and meta-analysis of observational studies that compared the risk of developing diabetic nephropathy in patients with and without glomerular hyperfiltration and also explored the impact of baseline GFR...
  34. doi request reprint Identifying additional patients with diabetic nephropathy using the UK primary care initiative
    G M Magee
    Regional Centre for Diabetes and Endocrinology, Royal Victoria Hospital, Belfast, Co Antrim, UK
    Diabet Med 27:1372-8. 2010
    ....
  35. ncbi request reprint Evaluation of a psychoeducational intervention for patients with advanced cancer who have cachexia and their lay carers (EPACaCC): study protocol
    Joanne Reid
    School of Nursing and Midwifery, Queen s University Belfast, UK
    J Adv Nurs 70:1174-83. 2014
    ..To evaluate a psychoeducational intervention for patients with advanced cancer who have cachexia and their lay carers...
  36. doi request reprint Dietary patterns and breast cancer risk: a systematic review and meta-analysis
    Sarah F Brennan
    Nutrition and Metabolism Group, Centre for Public Health, Queen s University Belfast, Royal Victoria Hospital, Belfast, United Kingdom
    Am J Clin Nutr 91:1294-302. 2010
    ..Dietary patterns, which represent whole-diet and possible food and nutrient interactions, have been linked to the risk of various cancers. However, the associations of these dietary patterns with breast cancer remain unclear...
  37. doi request reprint No association between routinely recorded infections in early life and subsequent risk of childhood-onset Type 1 diabetes: a matched case-control study using the UK General Practice Research Database
    C R Cardwell
    School of Medicine and Dentistry, The Queen s University of Belfast, Belfast, UK
    Diabet Med 25:261-7. 2008
    ..To determine whether children with infections in early life (recorded routinely in general practice) have a reduced risk of Type 1 diabetes, as would be expected from the hygiene hypothesis...
  38. doi request reprint Thalidomide for managing cancer cachexia
    Joanne Reid
    Nursing and Midwifery Research Unit, School of Nursing, Queen s University Belfast, Belfast, UK
    Cochrane Database Syst Rev 4:CD008664. 2012
    ..Preliminary studies of thalidomide have demonstrated encouraging results...
  39. doi request reprint Neonatal jaundice is associated with a small increase in the risk of childhood type 1 diabetes: a meta-analysis of observational studies
    Maria B McNamee
    Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, UK
    Acta Diabetol 49:83-7. 2012
    ..Jaundice caused by blood group incompatibility or requiring phototherapy may be associated with a greater increase in type 1 diabetes risk and deserves further study...
  40. pmc Maternal body mass index and risk of testicular cancer in male offspring: a systematic review and meta-analysis
    Shama S Alam
    Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen s University Belfast, Northern Ireland, United Kingdom
    Cancer Epidemiol 34:509-15. 2010
    ..This systematic review and meta-analysis investigated the nature of this association...
  41. doi request reprint Interventions to improve the appropriate use of polypharmacy for older people
    Susan M Patterson
    Health and Social Care Board, Belfast, UK
    Cochrane Database Syst Rev 5:CD008165. 2012
    ..Choosing the best interventions to improve appropriate polypharmacy is a priority, hence there is growing interest in appropriate polypharmacy, where many medicines may be used to achieve better clinical outcomes for patients...
  42. pmc A systematic review of population based epidemiological studies in Myasthenia Gravis
    Aisling S Carr
    Department of Neurology, Royal Victoria Hospital, Belfast, Northern Ireland, UK
    BMC Neurol 10:46. 2010
    ..To synthesize data on incidence rate (IR), prevalence rate (PR) and mortality rate (MR) of the condition and investigate the influence of environmental and technical factors on any trends or variation observed...
  43. doi request reprint A meta-analysis of the association between Caesarean section and childhood asthma
    S Thavagnanam
    Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland
    Clin Exp Allergy 38:629-33. 2008
    ..The results of previous studies that have investigated the association between Caesarean section and asthma have been conflicting...