Frederick C Campbell

Summary

Affiliation: Queen's University Belfast
Country: UK

Publications

  1. doi request reprint Vitamin D receptor modulates the neoplastic phenotype through antagonistic growth regulatory signals
    Haibo Xu
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Belfast, UK
    Mol Carcinog 48:758-72. 2009
  2. pmc PTEN regulates colorectal epithelial apoptosis through Cdc42 signalling
    R Deevi
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Lisburn Road, Belfast BT97BL, UK
    Br J Cancer 105:1313-21. 2011
  3. pmc Metallothionein crypt-restricted immunopositivity indices (MTCRII) correlate with aberrant crypt foci (ACF) in mouse colon
    E T Donnelly
    Departments of Surgery, Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Clinical Sciences Building, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland, UK
    Br J Cancer 92:2160-5. 2005
  4. pmc Expression of osteopontin coregulators in primary colorectal cancer and associated liver metastases
    D J Mole
    Clinical and Surgical Sciences Surgery, The University of Edinburgh, Edinburgh EH8 9YL, Scotland, UK
    Br J Cancer 104:1007-12. 2011
  5. ncbi request reprint Chemopreventive properties of curcumin
    Frederick C Campbell
    Queen s University of Belfast, Department of Surgery, Centre for Cancer and Cell Biology, Belfast, BT12 6BJ, Ireland
    Future Oncol 1:405-14. 2005
  6. pmc The yin and yang of vitamin D receptor (VDR) signaling in neoplastic progression: operational networks and tissue-specific growth control
    F C Campbell
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Lisburn Rd, Belfast BT9 7BL, Northern Ireland, UK
    Biochem Pharmacol 79:1-9. 2010
  7. ncbi request reprint Rationale for cancer prevention strategies in high-risk ulcerative colitis
    F C Campbell
    Centre for Cancer Research and Cell Biology, Lisburn Road, Queen s University of Belfast
    Surgeon 7:96-100. 2009
  8. pmc Apc(MIN) modulation of vitamin D secosteroid growth control
    Haibo Xu
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Northern Ireland, UK
    Carcinogenesis 31:1434-41. 2010
  9. ncbi request reprint Modulation of N-methyl-N-nitrosourea-induced crypt restricted metallothionein immunopositivity in mouse colon by a non-genotoxic diet-related chemical
    Eilish T Donnelly
    Department of Surgery, Cancer Centre, Queen s University Belfast, Belfast BT12 6BJ, Northern Ireland, UK
    Carcinogenesis 25:847-55. 2004
  10. ncbi request reprint The Drosophila ortholog of the endolysosomal membrane protein, endolyn, regulates cell proliferation
    Guang Qian Zhou
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Belfast, UK
    J Cell Biochem 99:1380-96. 2006

Collaborators

Detail Information

Publications11

  1. doi request reprint Vitamin D receptor modulates the neoplastic phenotype through antagonistic growth regulatory signals
    Haibo Xu
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Belfast, UK
    Mol Carcinog 48:758-72. 2009
    ..These findings may be relevant to the cell- or tissue-specificity of vitamin D growth regulation...
  2. pmc PTEN regulates colorectal epithelial apoptosis through Cdc42 signalling
    R Deevi
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Lisburn Road, Belfast BT97BL, UK
    Br J Cancer 105:1313-21. 2011
    ..Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) regulation of the Rho-like GTPase Cdc42 has a central role in epithelial polarised growth, but effects of this molecular network on apoptosis remain unclear...
  3. pmc Metallothionein crypt-restricted immunopositivity indices (MTCRII) correlate with aberrant crypt foci (ACF) in mouse colon
    E T Donnelly
    Departments of Surgery, Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Clinical Sciences Building, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland, UK
    Br J Cancer 92:2160-5. 2005
    ..MTCRII could thus provide the basis for a novel medium-term murine bioassay relevant to early-stage colorectal tumorigenesis...
  4. pmc Expression of osteopontin coregulators in primary colorectal cancer and associated liver metastases
    D J Mole
    Clinical and Surgical Sciences Surgery, The University of Edinburgh, Edinburgh EH8 9YL, Scotland, UK
    Br J Cancer 104:1007-12. 2011
    ..This study investigates expression and prognostic significance of the OPN-TRC in primary human CRC and associated colorectal liver metastases (CRLM)...
  5. ncbi request reprint Chemopreventive properties of curcumin
    Frederick C Campbell
    Queen s University of Belfast, Department of Surgery, Centre for Cancer and Cell Biology, Belfast, BT12 6BJ, Ireland
    Future Oncol 1:405-14. 2005
    ..This review will summarize the unique properties of curcumin that may be exploited for successful clinical cancer prevention...
  6. pmc The yin and yang of vitamin D receptor (VDR) signaling in neoplastic progression: operational networks and tissue-specific growth control
    F C Campbell
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Lisburn Rd, Belfast BT9 7BL, Northern Ireland, UK
    Biochem Pharmacol 79:1-9. 2010
    ..We highlight some differences of VDR growth control relevant to colonic, esophageal, prostate, pancreatic and other cancers and assess the potential for development of selective prevention or treatment strategies...
  7. ncbi request reprint Rationale for cancer prevention strategies in high-risk ulcerative colitis
    F C Campbell
    Centre for Cancer Research and Cell Biology, Lisburn Road, Queen s University of Belfast
    Surgeon 7:96-100. 2009
    ..Against this background, indications for surveillance and prophylactic colectomy in specific clinical situations will be discussed...
  8. pmc Apc(MIN) modulation of vitamin D secosteroid growth control
    Haibo Xu
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Northern Ireland, UK
    Carcinogenesis 31:1434-41. 2010
    ..APC heterozygosity may promote favourable tissue- or tumour-specific conditions for growth control by vitamin D secosteroid treatment...
  9. ncbi request reprint Modulation of N-methyl-N-nitrosourea-induced crypt restricted metallothionein immunopositivity in mouse colon by a non-genotoxic diet-related chemical
    Eilish T Donnelly
    Department of Surgery, Cancer Centre, Queen s University Belfast, Belfast BT12 6BJ, Northern Ireland, UK
    Carcinogenesis 25:847-55. 2004
    ..This study has shown that exposure to a non-genotoxic diet-related compound (lambdaCgN) modulates the effective NOC dosimetry for induction of MT crypt restricted immunopositivity...
  10. ncbi request reprint The Drosophila ortholog of the endolysosomal membrane protein, endolyn, regulates cell proliferation
    Guang Qian Zhou
    Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Belfast, UK
    J Cell Biochem 99:1380-96. 2006
    ..Taken together, these results demonstrate that endolyn is an evolutionarily conserved sialomucin fundamentally involved in cell proliferation in both the human and Drosophila melanogaster...
  11. ncbi request reprint Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells
    Gavin P Collett
    Department of Surgery, Centre for Cancer Research and Cell Biology, Queen s University Belfast, Belfast BT12 6BJ, UK
    Carcinogenesis 27:1285-91. 2006
    ..Furthermore, curcumin/p65 synergy in promotion of apoptosis cannot be attributed to active repression of NFkappaB anti-apoptotic genes...