Marie Cahir

Summary

Affiliation: Queen's University Belfast
Country: UK

Publications

  1. ncbi request reprint Differential region-specific regulation of central alpha 1-adrenoceptor binding following chronic haloperidol and clozapine administration in the rat
    Marie Cahir
    Department of Therapeutics and Pharmacology, Queen s University of Belfast, Whitla Medical Building, 97 Lisburn Road, BT9 7BL Belfast, Northern Ireland
    Psychopharmacology (Berl) 172:196-201. 2004
  2. ncbi request reprint Acute tryptophan depletion does not alter central or plasma brain-derived neurotrophic factor in the rat
    Marie Cahir
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Northern Ireland, UK
    Eur Neuropsychopharmacol 18:317-22. 2008
  3. ncbi request reprint Acute and chronic tryptophan depletion differentially regulate central 5-HT1A and 5-HT 2A receptor binding in the rat
    Marie Cahir
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Whitla, 97 Lisburn Road, Northern Ireland, UK
    Psychopharmacology (Berl) 190:497-506. 2007
  4. ncbi request reprint British Association for Psychopharmacology Summer Meeting: 23-26 July 2006, Oxford, United Kingdom
    Marie Cahir
    Division of Psychiatry and Neuroscience, Queen s University, Whitla Medical Building, 97 Lisburn Rd, Belfast, UK
    Expert Opin Pharmacother 7:2007-10. 2006
  5. ncbi request reprint Antipsychotics lack alpha 1A/B adrenoceptor subtype selectivity in the rat
    Marie Cahir
    Department of Mental Health, The Queen s University of Belfast, Whitla Medical Building, 97 Lisburn Rd, Belfast BT9 7BL, UK
    Eur Neuropsychopharmacol 15:231-4. 2005
  6. ncbi request reprint Chronic haloperidol or clozapine treatment does not alter parvalbumin immunoreactivity in the rat frontal cortex or hippocampus
    Marie Cahir
    Department of Mental Health, The Queen s University of Belfast, Whitla Medical Building, 97 Lisburn Rd, Belfast, BT9 7BL, UK
    Neurosci Lett 373:57-60. 2005
  7. doi request reprint Tryptophan depletion impairs object-recognition memory in the rat: reversal by risperidone
    Trisha A Jenkins
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Northern Ireland, United Kingdom
    Behav Brain Res 208:479-83. 2010
  8. ncbi request reprint Clozapine, but not haloperidol, increases neuropeptide Y neuronal expression in the rat hypothalamus
    Shona L Kirk
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Belfast, UK
    J Psychopharmacol 20:577-9. 2006
  9. ncbi request reprint Synthesis and structure-activity relationship of fluoro analogues of 8-{2-[4-(4-methoxyphenyl)piperazin-1yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione as selective alpha(1d)-adrenergic receptor antagonists
    Michael J Konkel
    Lundbeck Research USA, Inc, 215 College Road, Paramus, New Jersey 07652, USA
    J Med Chem 48:3076-9. 2005
  10. ncbi request reprint Sub-chronic phencyclidine administration increases brain-derived neurotrophic factor in the RAT hippocampus
    Michael K Harte
    Schizophr Res 94:371-2. 2007

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Differential region-specific regulation of central alpha 1-adrenoceptor binding following chronic haloperidol and clozapine administration in the rat
    Marie Cahir
    Department of Therapeutics and Pharmacology, Queen s University of Belfast, Whitla Medical Building, 97 Lisburn Road, BT9 7BL Belfast, Northern Ireland
    Psychopharmacology (Berl) 172:196-201. 2004
    ..Many antipsychotics exhibit potent anti-alpha(1)-adrenergic receptor activity, which has been suggested to contribute to typical and atypical antipsychotic effects and to the production of centrally mediated side effects...
  2. ncbi request reprint Acute tryptophan depletion does not alter central or plasma brain-derived neurotrophic factor in the rat
    Marie Cahir
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Northern Ireland, UK
    Eur Neuropsychopharmacol 18:317-22. 2008
    ..However, plasma or central BDNF protein levels in the hippocampus and midbrain were not significantly altered by ATD. These results suggest that changes in central BDNF do not contribute to the cognitive or mood effects of ATD...
  3. ncbi request reprint Acute and chronic tryptophan depletion differentially regulate central 5-HT1A and 5-HT 2A receptor binding in the rat
    Marie Cahir
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Whitla, 97 Lisburn Road, Northern Ireland, UK
    Psychopharmacology (Berl) 190:497-506. 2007
    ..Tryptophan depletion is used to reduce central serotonergic function and to investigate its role in psychiatric illness. Despite widespread clinical use, its effects on serotonin (5-HT) receptors have not been well characterized...
  4. ncbi request reprint British Association for Psychopharmacology Summer Meeting: 23-26 July 2006, Oxford, United Kingdom
    Marie Cahir
    Division of Psychiatry and Neuroscience, Queen s University, Whitla Medical Building, 97 Lisburn Rd, Belfast, UK
    Expert Opin Pharmacother 7:2007-10. 2006
    ....
  5. ncbi request reprint Antipsychotics lack alpha 1A/B adrenoceptor subtype selectivity in the rat
    Marie Cahir
    Department of Mental Health, The Queen s University of Belfast, Whitla Medical Building, 97 Lisburn Rd, Belfast BT9 7BL, UK
    Eur Neuropsychopharmacol 15:231-4. 2005
    ....
  6. ncbi request reprint Chronic haloperidol or clozapine treatment does not alter parvalbumin immunoreactivity in the rat frontal cortex or hippocampus
    Marie Cahir
    Department of Mental Health, The Queen s University of Belfast, Whitla Medical Building, 97 Lisburn Rd, Belfast, BT9 7BL, UK
    Neurosci Lett 373:57-60. 2005
    ....
  7. doi request reprint Tryptophan depletion impairs object-recognition memory in the rat: reversal by risperidone
    Trisha A Jenkins
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Northern Ireland, United Kingdom
    Behav Brain Res 208:479-83. 2010
    ..These data show that chronic lowering of central serotonin is associated with impaired cognitive performance, and that this can be reversed by the atypical antipsychotic, risperidone...
  8. ncbi request reprint Clozapine, but not haloperidol, increases neuropeptide Y neuronal expression in the rat hypothalamus
    Shona L Kirk
    Division of Psychiatry and Neuroscience, Queen s University Belfast, Belfast, UK
    J Psychopharmacol 20:577-9. 2006
    ..p.) for 3 weeks. Clozapine, but not haloperidol, produced an increase in NPY immunoreactivity in the ARC, suggesting that effects on NPY may be involved in increases in body weight following clozapine treatment...
  9. ncbi request reprint Synthesis and structure-activity relationship of fluoro analogues of 8-{2-[4-(4-methoxyphenyl)piperazin-1yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione as selective alpha(1d)-adrenergic receptor antagonists
    Michael J Konkel
    Lundbeck Research USA, Inc, 215 College Road, Paramus, New Jersey 07652, USA
    J Med Chem 48:3076-9. 2005
    ....
  10. ncbi request reprint Sub-chronic phencyclidine administration increases brain-derived neurotrophic factor in the RAT hippocampus
    Michael K Harte
    Schizophr Res 94:371-2. 2007