Research Topics
Genomes and Genes
Species | Kenta YashiroSummaryAffiliation: Queen Mary Country: UK Publications
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Detail Information
Publications
Haemodynamics determined by a genetic programme govern asymmetric development of the aortic archKenta Yashiro
Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, 1 3 Yamada oka, Suita, Osaka 565 0871, Japan
Nature 450:285-8. 2007..Our results therefore indicate that haemodynamics, generated by a Pitx2-induced morphological change in the outflow tract, is responsible for the asymmetric remodelling of the great arteries...
Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterningMasayuki Uehara
Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan
Genes Dev 23:1689-98. 2009..These observations suggest that maternal RA must be removed by embryonic CYP26 for correct Nodal expression during embryonic patterning...- CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouseMasayuki Uehara
Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, Osaka 565 0871, Japan
Dev Biol 302:399-411. 2007.... 
Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryosAiko Kawasumi
Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, 1 3 Yamada oka, Suita, Osaka 565 0871, Japan
Dev Biol 353:321-30. 2011..Our results suggest that LPM is the direct target of Nodal secreted by the perinodal cells, and that an L>R distribution of active Nodal in the node is translated into the asymmetry in LPM...- Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition systemTetsuya Nakamura
Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University and CREST SORST, Japan Science and Technology Corporation, Suita, Osaka 565 0871, Japan
Dev Cell 11:495-504. 2006..Nodal and Lefty are deployed as a SELI system required to amplify this initial bias and convert it into robust asymmetry... - Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organsHidetaka Shiratori
Developmental Genetics Group, Graduate School for Frontier Biosciences, Osaka University, and CREST, Japan Science and Technology Corporation JST Yamada oka, Suita, Osaka 565 0871, Japan
Development 133:3015-25. 2006.... - EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteinsZili Lei
Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, 1 3 Yamada oka, Suita, Osaka 565 0871, Japan
Dev Biol 371:136-45. 2012..Finally, the barrier function of the intestinal epithelium was impaired in the mutant animals. These results suggest that EpCAM contributes to formation of intestinal barrier by recruiting claudins to cell-cell junctions... - Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limbKenta Yashiro
Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan
Dev Cell 6:411-22. 2004..These observations suggest that RA acts as a morphogen to determine proximodistal identity, and that CYP26B1 prevents apoptosis and promotes chondrocyte maturation, in the developing limb...