Kenta Yashiro

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. ncbi request reprint Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch
    Kenta Yashiro
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, 1 3 Yamada oka, Suita, Osaka 565 0871, Japan
    Nature 450:285-8. 2007
  2. pmc Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning
    Masayuki Uehara
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan
    Genes Dev 23:1689-98. 2009
  3. ncbi request reprint CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse
    Masayuki Uehara
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, Osaka 565 0871, Japan
    Dev Biol 302:399-411. 2007
  4. doi request reprint Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos
    Aiko Kawasumi
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, 1 3 Yamada oka, Suita, Osaka 565 0871, Japan
    Dev Biol 353:321-30. 2011
  5. ncbi request reprint Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system
    Tetsuya Nakamura
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University and CREST SORST, Japan Science and Technology Corporation, Suita, Osaka 565 0871, Japan
    Dev Cell 11:495-504. 2006
  6. ncbi request reprint Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
    Hidetaka Shiratori
    Developmental Genetics Group, Graduate School for Frontier Biosciences, Osaka University, and CREST, Japan Science and Technology Corporation JST Yamada oka, Suita, Osaka 565 0871, Japan
    Development 133:3015-25. 2006
  7. doi request reprint EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins
    Zili Lei
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, 1 3 Yamada oka, Suita, Osaka 565 0871, Japan
    Dev Biol 371:136-45. 2012
  8. ncbi request reprint Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb
    Kenta Yashiro
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan
    Dev Cell 6:411-22. 2004

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch
    Kenta Yashiro
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, 1 3 Yamada oka, Suita, Osaka 565 0871, Japan
    Nature 450:285-8. 2007
    ..Our results therefore indicate that haemodynamics, generated by a Pitx2-induced morphological change in the outflow tract, is responsible for the asymmetric remodelling of the great arteries...
  2. pmc Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning
    Masayuki Uehara
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan
    Genes Dev 23:1689-98. 2009
    ..These observations suggest that maternal RA must be removed by embryonic CYP26 for correct Nodal expression during embryonic patterning...
  3. ncbi request reprint CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse
    Masayuki Uehara
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, Osaka 565 0871, Japan
    Dev Biol 302:399-411. 2007
    ....
  4. doi request reprint Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos
    Aiko Kawasumi
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, 1 3 Yamada oka, Suita, Osaka 565 0871, Japan
    Dev Biol 353:321-30. 2011
    ..Our results suggest that LPM is the direct target of Nodal secreted by the perinodal cells, and that an L>R distribution of active Nodal in the node is translated into the asymmetry in LPM...
  5. ncbi request reprint Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system
    Tetsuya Nakamura
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University and CREST SORST, Japan Science and Technology Corporation, Suita, Osaka 565 0871, Japan
    Dev Cell 11:495-504. 2006
    ..Nodal and Lefty are deployed as a SELI system required to amplify this initial bias and convert it into robust asymmetry...
  6. ncbi request reprint Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
    Hidetaka Shiratori
    Developmental Genetics Group, Graduate School for Frontier Biosciences, Osaka University, and CREST, Japan Science and Technology Corporation JST Yamada oka, Suita, Osaka 565 0871, Japan
    Development 133:3015-25. 2006
    ....
  7. doi request reprint EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins
    Zili Lei
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, 1 3 Yamada oka, Suita, Osaka 565 0871, Japan
    Dev Biol 371:136-45. 2012
    ..Finally, the barrier function of the intestinal epithelium was impaired in the mutant animals. These results suggest that EpCAM contributes to formation of intestinal barrier by recruiting claudins to cell-cell junctions...
  8. ncbi request reprint Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb
    Kenta Yashiro
    Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan
    Dev Cell 6:411-22. 2004
    ..These observations suggest that RA acts as a morphogen to determine proximodistal identity, and that CYP26B1 prevents apoptosis and promotes chondrocyte maturation, in the developing limb...