Research Topics
| C A WellsSummaryAffiliation: Queen Mary Country: UK Publications
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Detail Information
Publications
Non-operative breast pathology: apocrine lesionsC A Wells
St Bartholomew s Hospital, London, UK
J Clin Pathol 60:1313-20. 2007..This review considers the common apocrine metaplastic lesions seen in fibrocystic change as well as apocrine adenoma, apocrine change within sclerosing adenosis, atypical apocrine lesions and apocrine malignancies...
Consistency of staining and reporting of oestrogen receptor immunocytochemistry within the European Union--an inter-laboratory studyC A Wells
Department of Histopathology, St Bartholomew s Hospital Medical School, West Smithfield, London, EC1A 7BE, United Kingdom
Virchows Arch 445:119-28. 2004..The Quick score method of receptor assessment may also have too many categories for good concordance, and grouping of these into fewer categories may remove some of the variation among laboratories...
99mTc-labelled SM3 in the preoperative evaluation of axillary lymph nodes and primary breast cancer with change detection statistical processing as an aid to tumour detectionL Biassoni
Department of Nuclear Medicine and Research Laboratory, St Bartholomew s Hospital, The Royal Hospitals NHS Trust, London, UK
Br J Cancer 77:131-8. 1998..Sensitivity was 90% (nine out of ten), specificity 84% (16 out of 19) and accuracy 86%. These results encourage further assessment of this technique...
Modulation of very late activation-2 laminin receptor function in breast cancer metastasisG P Gui
Department of Surgery, St Bartholomew s Hospital, London, UK
Surgery 118:245-50. 1995..001). CONCLUSIONS. VLA-2-mediated adhesion of primary breast cancer cells to laminin differs with nodal status. Measurement of VLA-2 expression may thus be of clinical value as a prognostic indicator in the assessment of breast cancer...
Immunohistochemical localisation of androgen receptor in apocrine metaplasia and apocrine adenosis of the breast: relation to oestrogen and progesterone receptorsA G Selim
Department of Histopathology, St Bartholomew s Hospital, West Smithfield, London, UK
J Clin Pathol 52:838-41. 1999..To investigate the receptor status of the sex steroid hormones in apocrine metaplasia of the breast...
The role of radiotherapy in treating small early invasive breast cancerP Varghese
Breast Unit, St Bartholomew s Hospital, Queen Mary University of London, London, UK
Eur J Surg Oncol 34:369-76. 2008..The aim of the study was to identify if radiotherapy can be safely avoided in a selected subgroup of largely screening detected small invasive breast cancer...
Methylene blue dye versus combined dye-radioactive tracer technique for sentinel lymph node localisation in early breast cancerP Varghese
Breast Unit, St Bartholomew s Hospital, Queen Mary University of London, London, UK
Eur J Surg Oncol 33:147-52. 2007..The study compared the accuracy and success rate of two techniques, methylene blue alone versus combined methylene blue and radioactive colloid in sentinel lymph node localisation in the management early breast cancer...
Integrin expression and survival in human breast cancerM G Berry
Department of Academic Surgery, St Bartholomew's and The Royal London Hospitals School of Medicine and Dentistry, London, UK
Eur J Surg Oncol 30:484-9. 2004..Despite proven molecular importance in tumour cell adhesion, invasion and metastasis, integrin expression would appear not to translate clinically as independent indicators of prognosis, at least in the short-term...
Predictive markers in breast cancer--the presentS J L Payne
Tumour Biology Laboratory, Institute of Cancer, John Vane Science Centre, Queen Mary s School of Medicine and Dentistry, London, UK
Histopathology 52:82-90. 2008....
Loss of heterozygosity and allelic imbalance in apocrine adenosis of the breastA G Selim
Department of Histopathology, St Bartholomew's and the Royal London School of Medicine and Dentistry, St Bartholomew's Hospital, London, United Kingdom
Cancer Detect Prev 25:262-7. 2001....
Immunohistochemical localization of gross cystic disease fluid protein-15, -24 and -44 in ductal carcinoma in situ of the breast: relationship to the degree of differentiationA A Selim
Department of Histopathology, St Bartholomew s Hospital, St Bartholomew s and the Royal London School of Medicine and Dentistry, West Smithfield, London EC1A 7BE, UK
Histopathology 39:198-202. 2001..The aim of this study was to investigate the expression of these proteins in ductal carcinoma in situ (DCIS) of the breast and to relate their expression with the degree of differentiation of DCIS...
c-erbB2 oncoprotein expression, gene amplification, and chromosome 17 aneusomy in apocrine adenosis of the breastA G Selim
Department of Histopathology, St Bartholomew s Hospital, St Bartholomew s and the Royal London School of Medicine and Dentistry, University of London, UK
J Pathol 191:138-42. 2000..Amplification and numerical chromosome aberrations may occur later in the pathogenesis of apocrine-derived breast carcinomas...
Best Practice No 179. Guidelines for breast needle core biopsy handling and reporting in breast screening assessmentI O Ellis
Department of Histopathology, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
J Clin Pathol 57:897-902. 2004..This guidance has been produced by the UK National Coordinating Committee for Breast Screening Pathology and is endorsed by the European Commission working group on breast screening pathology...
Altered cell-matrix contact: a prerequisite for breast cancer metastasis?G P Gui
Department of Surgery, St Bartholomew s Hospital, West Smithfield, London, UK
Br J Cancer 75:623-33. 1997..This study demonstrates a link between altered integrin expression and function in primary breast cancers predisposed to metastasize...
How significant is detection of ductal carcinoma in situ in a breast screening programme?P Kessar
Department of Radiology, St Bartholomew s Hospital, London, UK
Clin Radiol 57:807-14. 2002..The aim was also to establish whether any particular mammographic features of DCIS can be used to predict tumour grade reliably...
Inadequate rates are lower when FNAC samples are taken by cytopathologistsN Singh
Department of Histopathology, St Bartholomew s Hospital, West Smithfield, London, UK
Cytopathology 14:327-31. 2003..These differences were mirrored in high IRs in breast cancer cases. IR was not significantly improved when non-cytopathologist FNAC was attended by a cytotechnician...
Axillary node status in breast cancer patients prior to surgery by imaging with Tc-99m humanised anti-PEM monoclonal antibody, hHMFG1A R Al Yasi
Department of Nuclear Medicine, St Bartholomew s Hospital, London EC1A 7BE, UK
Br J Cancer 86:870-8. 2002..A specificity of 93% and positive predictive value of 92% (both 100% if a second cancer in the axilla with negative nodes is considered) were found. A strategy for combining negative imaging with the sentinel node procedure is presented...
Androgen receptor expression in ductal carcinoma in situ of the breast: relation to oestrogen and progesterone receptorsA G A Selim
Department of Histopathology, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
J Clin Pathol 55:14-6. 2002..In contrast to the situation in invasive breast carcinoma, there are no reports on androgen receptor (AR) status in DCIS and few reports on oestrogen (ER) and progesterone (PR) receptors...
Angiosarcoma of the breast after wide local excision and radiotherapy for breast carcinomaT D Mills
St Bartholomew's Hospital, London, UK
Clin Radiol 57:63-6. 2002
Discrepancies in current practice of pathological evaluation of sentinel lymph nodes in breast cancer. Results of a questionnaire based survey by the European Working Group for Breast Screening PathologyG Cserni
Department of Pathology, Bacs Kiskun County Teaching Hospital, H 6000 Kecskemet, Hungary
J Clin Pathol 57:695-701. 2004....
Pathological work-up of sentinel lymph nodes in breast cancer. Review of current data to be considered for the formulation of guidelinesG Cserni
Department of Pathology, , , Hungary
Eur J Cancer 39:1654-67. 2003..e. approximately 2% of all patients initially staged by SN biopsy. The methods for the intraoperative and molecular assessment of SNs are also surveyed...
