David Wald

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. pmc Randomized Polypill crossover trial in people aged 50 and over
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
    PLoS ONE 7:e41297. 2012
  2. ncbi request reprint Randomized trial of preventive angioplasty in myocardial infarction
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
    N Engl J Med 369:1115-23. 2013
  3. doi request reprint The polypill and the prevention of heart attacks and strokes
    David S Wald
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, London, EC1M 6BQ, UK
    Future Cardiol 9:465-6. 2013
  4. doi request reprint Implementation of a simple age-based strategy in the prevention of cardiovascular disease: the Polypill approach
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, Charterhouse Square, London, UK
    J Eval Clin Pract 18:612-5. 2012
  5. doi request reprint Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials
    David S Wald
    Wolfson Institute of Preventive Medicine at Barts and The London Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London, United Kingdom
    Am J Med 122:290-300. 2009
  6. doi request reprint Carotid ultrasound screening for coronary heart disease: results based on a meta-analysis of 18 studies and 44,861 subjects
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London, UK
    J Med Screen 16:147-54. 2009
  7. doi request reprint Combining carotid intima-media thickness with carotid plaque on screening for coronary heart disease
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London, UK
    J Med Screen 16:155-9. 2009
  8. doi request reprint The polypill in the primary prevention of cardiovascular disease
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University, London EC1M 6BQ, UK
    Fundam Clin Pharmacol 24:29-35. 2010
  9. doi request reprint The value of C-reactive protein in screening for future coronary heart disease events
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, Charterhouse Square, London EC1M 6BQ, UK
    J Med Screen 16:212-4. 2009
  10. doi request reprint Effect of folic acid, with or without other B vitamins, on cognitive decline: meta-analysis of randomized trials
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London, UK
    Am J Med 123:522-527.e2. 2010

Collaborators

Detail Information

Publications30

  1. pmc Randomized Polypill crossover trial in people aged 50 and over
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
    PLoS ONE 7:e41297. 2012
    ..A Polypill is proposed for the primary prevention of cardiovascular disease in people judged to be at risk on account of their age alone. Its efficacy in reducing cholesterol and blood pressure is uncertain...
  2. ncbi request reprint Randomized trial of preventive angioplasty in myocardial infarction
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
    N Engl J Med 369:1115-23. 2013
    ..The value of PCI in noninfarct coronary arteries with major stenoses (preventive PCI) is unknown...
  3. doi request reprint The polypill and the prevention of heart attacks and strokes
    David S Wald
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, London, EC1M 6BQ, UK
    Future Cardiol 9:465-6. 2013
    ....
  4. doi request reprint Implementation of a simple age-based strategy in the prevention of cardiovascular disease: the Polypill approach
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, Charterhouse Square, London, UK
    J Eval Clin Pract 18:612-5. 2012
    ....
  5. doi request reprint Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials
    David S Wald
    Wolfson Institute of Preventive Medicine at Barts and The London Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London, United Kingdom
    Am J Med 122:290-300. 2009
    ....
  6. doi request reprint Carotid ultrasound screening for coronary heart disease: results based on a meta-analysis of 18 studies and 44,861 subjects
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London, UK
    J Med Screen 16:147-54. 2009
    ..Carotid artery ultrasound is a possible screening test for future coronary heart disease (CHD) events to select individuals for preventive treatment...
  7. doi request reprint Combining carotid intima-media thickness with carotid plaque on screening for coronary heart disease
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London, UK
    J Med Screen 16:155-9. 2009
    ..Ultrasound-detected carotid artery intima-media thickness (IMT) and carotid plaque are possible screening tests for coronary heart disease (CHD) among asymptomatic individuals...
  8. doi request reprint The polypill in the primary prevention of cardiovascular disease
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University, London EC1M 6BQ, UK
    Fundam Clin Pharmacol 24:29-35. 2010
    ..Age alone is effective and a simpler means of selecting people for preventive treatment using the polypill...
  9. doi request reprint The value of C-reactive protein in screening for future coronary heart disease events
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, Charterhouse Square, London EC1M 6BQ, UK
    J Med Screen 16:212-4. 2009
    ..65 mg/L); a poor screening test. Whatever CRP cut-off is used, the overlap in CRP values between affected and unaffected individuals is too great for CRP to usefully discriminate between those who will and will not have a CHD event...
  10. doi request reprint Effect of folic acid, with or without other B vitamins, on cognitive decline: meta-analysis of randomized trials
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London, UK
    Am J Med 123:522-527.e2. 2010
    ..We aimed to quantify the effect of folic acid supplementation on the prevention of cognitive decline...
  11. pmc Reconciling the evidence on serum homocysteine and ischaemic heart disease: a meta-analysis
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom
    PLoS ONE 6:e16473. 2011
    ..We aimed to update meta-analyses on each type of study using the latest published data and test a hypothesis based on antiplatelet therapy use in the trials to explain the discrepancy...
  12. doi request reprint Serum homocysteine and dementia: meta-analysis of eight cohort studies including 8669 participants
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom
    Alzheimers Dement 7:412-7. 2011
    ..Prospective cohort studies have not been consistent in showing an association between serum homocysteine and dementia...
  13. doi request reprint Child-parent screening for familial hypercholesterolemia
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    J Pediatr 159:865-7. 2011
    ..Simultaneous immunization-cholesterol measurement was successful in all children. Population child-parent screening is feasible and acceptable when combined with pediatric immunization...
  14. doi request reprint Commentary: Controversies in NICE guidance on familial hypercholesterolaemia
    David Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, London EC1M 6BQ
    BMJ 337:a1304. 2008
  15. pmc Bureaucracy of ethics applications
    David S Wald
    Wolfson Institute of Preventive Medicine, London EC1M 6BQ
    BMJ 329:282-4. 2004
  16. pmc Folic acid, homocysteine, and cardiovascular disease: judging causality in the face of inconclusive trial evidence
    David S Wald
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, London EC1M 6BQ
    BMJ 333:1114-7. 2006
  17. pmc Child-parent screening for familial hypercholesterolaemia: screening strategy based on a meta-analysis
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, London EC1M 6BQ
    BMJ 335:599. 2007
    ..To develop a population screening strategy for familial hypercholesterolaemia...
  18. ncbi request reprint The future of coronary heart disease prevention
    David S Wald
    Institute of Preventive Medicine, and London Chest Hospital Barts and The London, Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London
    Clin Med 7:392-6. 2007
  19. doi request reprint A 16-week, randomized, double-blind, placebo-controlled, crossover trial to quantify the combined effect of an angiotensin-converting enzyme inhibitor and a beta-blocker on blood pressure reduction
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, University of London, London, United Kingdom
    Clin Ther 30:2030-9. 2008
    ..Although beta-blockers and angiotensin-converting enzyme (ACE) inhibitors are often used together, there is a lack of quantitative evidence for the efficacy of this combination in reducing blood pressure (BP)...
  20. ncbi request reprint The dose-response relation between serum homocysteine and cardiovascular disease: implications for treatment and screening
    David S Wald
    Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1 M 6BQ, UK
    Eur J Cardiovasc Prev Rehabil 11:250-3. 2004
    ..It is uncertain whether treatment is best directed at those with high homocysteine or those at high risk irrespective of initial homocysteine...
  21. ncbi request reprint Long-term continuation on cardiovascular drug treatment in patients with coronary heart disease
    David S Wald
    Wolfson Institute of Preventive Medicine, London, England
    Ann Pharmacother 41:1644-7. 2007
    ..Combination therapy to reduce risk factors is effective in preventing recurrent cardiovascular disease events in patients with coronary heart disease (CHD), but medications need to be continued indefinitely to maximize the benefits...
  22. pmc Folate and risk of cardiovascular disease. Study results were misinterpreted
    David S Wald
    BMJ 326:1035; author reply 1035. 2003
  23. ncbi request reprint Serum homocysteine and the severity of coronary artery disease
    David S Wald
    Department of Cardiology, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
    Thromb Res 111:55-7. 2003
  24. ncbi request reprint Vitamin supplementation and risk of stroke
    David S Wald
    JAMA 291:2191; author reply 2191-2. 2004
  25. doi request reprint Meta-analysis audit trail
    Nicholas J Wald
    Lancet 371:558. 2008
  26. ncbi request reprint Mortality from hypertrophic cardiomyopathy in England and Wales: clinical and screening implications
    David S Wald
    Department of Cardiology, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
    Int J Cardiol 97:479-84. 2004
    ....
  27. ncbi request reprint Carney complex
    Rayhaneh G Zahedi
    Southampton University Hospital, Southampton, Hampshire, United Kingdom
    Ann Thorac Surg 82:320-2. 2006
    ..The importance of regular life-long echocardiographic screening and surveillance in all family members of affected cases is emphasized...
  28. pmc Problems with performance related pay in primary care
    David S Wald
    BMJ 335:523. 2007
  29. pmc Familial hypercholesterolaemia: screening needs a fresh approach
    David S Wald
    BMJ 335:1007-8. 2007
  30. pmc Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis
    David S Wald
    Department of Cardiology, Southampton General Hospital, Southampton SO16 6YD
    BMJ 325:1202. 2002
    ....