Matthew H Todd

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. ncbi request reprint Computer-aided organic synthesis
    Matthew H Todd
    Department of Chemistry, Queen Mary, University of London, Mile End Road, London, UKE1 4NS
    Chem Soc Rev 34:247-66. 2005
  2. ncbi request reprint Amino acid derived heterocycles: lewis acid catalyzed and radical cyclizations from peptide acetals
    Matthew H Todd
    Center for New Directions in Organic Synthesis, Department of Chemistry, University of California, Berkeley 94720 1460, USA
    J Org Chem 67:3985-8. 2002
  3. ncbi request reprint Design and synthesis of new tetrazolyl- and carboxy-biphenylylmethyl-quinazolin-4-one derivatives as angiotensin II AT1 receptor antagonists
    Mohamed A H Ismail
    Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, ElKhalifa ElMaamoon St, 11566, Abbasseya, Cairo, Egypt
    J Med Chem 49:1526-35. 2006

Collaborators

Detail Information

Publications3

  1. ncbi request reprint Computer-aided organic synthesis
    Matthew H Todd
    Department of Chemistry, Queen Mary, University of London, Mile End Road, London, UKE1 4NS
    Chem Soc Rev 34:247-66. 2005
    ..Here the analogy between synthesis and chess is outlined. Achievements in the 35-year history of computer-aided synthetic design are described, followed by some more recent developments...
  2. ncbi request reprint Amino acid derived heterocycles: lewis acid catalyzed and radical cyclizations from peptide acetals
    Matthew H Todd
    Center for New Directions in Organic Synthesis, Department of Chemistry, University of California, Berkeley 94720 1460, USA
    J Org Chem 67:3985-8. 2002
    ..Additional versatility in this process was demonstrated by efficient synthesis of a different fused ring system, represented by the antihelmintic praziquantel, 8...
  3. ncbi request reprint Design and synthesis of new tetrazolyl- and carboxy-biphenylylmethyl-quinazolin-4-one derivatives as angiotensin II AT1 receptor antagonists
    Mohamed A H Ismail
    Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, ElKhalifa ElMaamoon St, 11566, Abbasseya, Cairo, Egypt
    J Med Chem 49:1526-35. 2006
    ..To obtain a highly active compound from a candidate set of only eight tested compounds illustrates the power and utility of our pharmacophore model...