Rupert M Pearse

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. pmc Mortality after surgery in Europe: a 7 day cohort study
    Rupert M Pearse
    Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Lancet 380:1059-65. 2012
  2. pmc Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial
    Shaman Jhanji
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, Turner Street, London E1 2AD, UK
    Crit Care 14:R151. 2010
  3. doi request reprint Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications
    Shaman Jhanji
    William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK
    Intensive Care Med 35:671-7. 2009
  4. doi request reprint Early microvascular changes in sepsis and severe sepsis
    Angeliki Spanos
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, London, United Kingdom
    Shock 33:387-91. 2010
  5. pmc Comparison of three methods of extravascular lung water volume measurement in patients after cardiac surgery
    Benjamin Maddison
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, Royal London Hospital, London E1 1BB, UK
    Crit Care 13:R107. 2009
  6. pmc Use of inotropes and vasopressor agents in critically ill patients
    Mansoor N Bangash
    William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK
    Br J Pharmacol 165:2015-33. 2012
  7. doi request reprint The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock
    Shaman Jhanji
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, London, United Kingdom
    Crit Care Med 37:1961-6. 2009
  8. pmc The incidence of myocardial injury following post-operative Goal Directed Therapy
    Rupert M Pearse
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, UK
    BMC Cardiovasc Disord 7:10. 2007
  9. pmc Extending the role of lactate measurement into the prehospital environment
    Rupert M Pearse
    Intensive Care Unit, Royal London Hospital, Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, London, UK
    Crit Care 13:115. 2009
  10. doi request reprint Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry
    Benjamin Maddison
    Intensive Care Unit, Royal London Hospital, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Intensive Care Med 34:2106-11. 2008

Detail Information

Publications13

  1. pmc Mortality after surgery in Europe: a 7 day cohort study
    Rupert M Pearse
    Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Lancet 380:1059-65. 2012
    ..The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe...
  2. pmc Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial
    Shaman Jhanji
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, Turner Street, London E1 2AD, UK
    Crit Care 14:R151. 2010
    ....
  3. doi request reprint Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications
    Shaman Jhanji
    William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK
    Intensive Care Med 35:671-7. 2009
    ..To evaluate the relationship between global oxygen delivery (DO(2)I), microvascular flow and tissue oxygenation in patients who did and did not develop complications following major abdominal surgery...
  4. doi request reprint Early microvascular changes in sepsis and severe sepsis
    Angeliki Spanos
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, London, United Kingdom
    Shock 33:387-91. 2010
    ..These abnormalities are more marked in the most severely ill patients. Further research is required to fully characterize the effects of sepsis on microvascular function...
  5. pmc Comparison of three methods of extravascular lung water volume measurement in patients after cardiac surgery
    Benjamin Maddison
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, Royal London Hospital, London E1 1BB, UK
    Crit Care 13:R107. 2009
    ..Measurement of extravascular lung water (EVLW) by using the lithium-thermal (Li-thermal) and single-thermal indicator dilution methods was compared with the indocyanine green-thermal (ICG-thermal) method in humans...
  6. pmc Use of inotropes and vasopressor agents in critically ill patients
    Mansoor N Bangash
    William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK
    Br J Pharmacol 165:2015-33. 2012
    ..The purpose of this article is to describe the pharmacology and clinical applications of inotropic and vasopressor agents in critically ill patients...
  7. doi request reprint The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock
    Shaman Jhanji
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, London, United Kingdom
    Crit Care Med 37:1961-6. 2009
    ..To investigate the effect of escalating doses of norepinephrine, aimed at achieving incremental increases in mean arterial pressure (MAP), on microvascular flow and tissue oxygenation in patients with septic shock...
  8. pmc The incidence of myocardial injury following post-operative Goal Directed Therapy
    Rupert M Pearse
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, UK
    BMC Cardiovasc Disord 7:10. 2007
    ..However, there is concern that pre-emptive use of inotropic therapy may lead to an increased incidence of myocardial ischaemia and infarction...
  9. pmc Extending the role of lactate measurement into the prehospital environment
    Rupert M Pearse
    Intensive Care Unit, Royal London Hospital, Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, London, UK
    Crit Care 13:115. 2009
    ..Larger observational and interventional trials are needed to confirm the clinical value of serum lactate measurement in the prehospital environment...
  10. doi request reprint Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry
    Benjamin Maddison
    Intensive Care Unit, Royal London Hospital, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Intensive Care Med 34:2106-11. 2008
    ....
  11. doi request reprint Do integrated care pathways have a place in critical care?
    Stephen R Ford
    Adult Critical Care Unit, Royal London Hospital, Whitechapel, London, UK
    Curr Opin Crit Care 18:683-7. 2012
    ..Within other specialities, integrated care pathways (ICPs) have been advocated as an effective means of improving practice. We review the published research regarding their efficacy and potential role in critical care...
  12. doi request reprint The use of early intervention to prevent postoperative complications
    Shaman Jhanji
    Barts and the London School of Medicine and Dentistry, Queen Mary s University of London, London, UK
    Curr Opin Crit Care 15:349-54. 2009
    ..Patients who develop complications suffer a reduction in long-term survival. This review aims to explore recent advances in the management of surgical patients aimed at preventing postoperative complications...
  13. pmc Identification and characterisation of the high-risk surgical population in the United Kingdom
    Rupert M Pearse
    William Harvey Research Institute, Queen Mary s School of Medicine and Dentistry, London, UK
    Crit Care 10:R81. 2006
    ..The aim of the present study was to estimate the size of the high-risk general surgical population and to describe the outcome and intensive care unit (ICU) resource use...