Malcolm R Law

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. ncbi A change in paradigm: lowering blood pressure in everyone over a certain age
    Malcolm Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Ann Med 44:S30-5. 2012
  2. ncbi Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies
    M R Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ
    BMJ 338:b1665. 2009
  3. ncbi Vitamin D supplementation and the prevention of fractures and falls: results of a randomised trial in elderly people in residential accommodation
    Malcolm Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Age Ageing 35:482-6. 2006
  4. ncbi Statin safety: a systematic review
    Malcolm Law
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, London, United Kingdom
    Am J Cardiol 97:52C-60C. 2006
  5. ncbi Headaches and the treatment of blood pressure: results from a meta-analysis of 94 randomized placebo-controlled trials with 24,000 participants
    Malcolm Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts, UK
    Circulation 112:2301-6. 2005
  6. ncbi The prevention of neonatal group B streptococcal disease: a report by a working group of the Medical Screening Society
    M R Law
    Wolfson Institute of Preventive Medicine, Barts and The London Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1 M 6BQ, UK
    J Med Screen 12:60-8. 2005
  7. ncbi Changes in atopy over a quarter of a century, based on cross sectional data at three time periods
    Malcolm Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, London EC1M 6BQ
    BMJ 330:1187-8. 2005
  8. ncbi Risk factor thresholds: their existence under scrutiny
    M R Law
    Wolfson Institute of Preventive Medicine, Department of Environmental and Preventive Medicine, Barts and The London, Queen Mary's School of Medicine and Dentistry, London EC1M 6BQ
    BMJ 324:1570-6. 2002
  9. ncbi The underlying risk of death after myocardial infarction in the absence of treatment
    Malcolm R Law
    Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Queen Mary s School of Medicine and Dentistry, University of London, Charterhouse Square, London EC1M 6BQ, England
    Arch Intern Med 162:2405-10. 2002
  10. ncbi Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis
    M R Law
    Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, University of London, London EC1M 6BQ
    BMJ 326:1423. 2003

Detail Information

Publications19

  1. ncbi A change in paradigm: lowering blood pressure in everyone over a certain age
    Malcolm Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Ann Med 44:S30-5. 2012
    ..In primary prevention, basing treatment on age alone rather than overall absolute risk entails little loss of efficacy and may be preferred on the basis of simplicity and avoidance of anxiety in telling people they are at elevated risk...
  2. ncbi Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies
    M R Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ
    BMJ 338:b1665. 2009
    ..To determine the quantitative efficacy of different classes of blood pressure lowering drugs in preventing coronary heart disease (CHD) and stroke, and who should receive treatment...
  3. ncbi Vitamin D supplementation and the prevention of fractures and falls: results of a randomised trial in elderly people in residential accommodation
    Malcolm Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Age Ageing 35:482-6. 2006
    ..To determine whether vitamin D supplementation reduces the risk of fracture or falls in elderly people in care home accommodation...
  4. ncbi Statin safety: a systematic review
    Malcolm Law
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, London, United Kingdom
    Am J Cardiol 97:52C-60C. 2006
    ..No change in cognitive function was found in randomized trials of statins in elderly patients...
  5. ncbi Headaches and the treatment of blood pressure: results from a meta-analysis of 94 randomized placebo-controlled trials with 24,000 participants
    Malcolm Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts, UK
    Circulation 112:2301-6. 2005
    ..Uncertainty exists over whether blood pressure-lowering drugs prevent headache...
  6. ncbi The prevention of neonatal group B streptococcal disease: a report by a working group of the Medical Screening Society
    M R Law
    Wolfson Institute of Preventive Medicine, Barts and The London Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1 M 6BQ, UK
    J Med Screen 12:60-8. 2005
    ....
  7. ncbi Changes in atopy over a quarter of a century, based on cross sectional data at three time periods
    Malcolm Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, London EC1M 6BQ
    BMJ 330:1187-8. 2005
  8. ncbi Risk factor thresholds: their existence under scrutiny
    M R Law
    Wolfson Institute of Preventive Medicine, Department of Environmental and Preventive Medicine, Barts and The London, Queen Mary's School of Medicine and Dentistry, London EC1M 6BQ
    BMJ 324:1570-6. 2002
  9. ncbi The underlying risk of death after myocardial infarction in the absence of treatment
    Malcolm R Law
    Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Queen Mary s School of Medicine and Dentistry, University of London, Charterhouse Square, London EC1M 6BQ, England
    Arch Intern Med 162:2405-10. 2002
    ..The underlying risk of death in the absence of treatment after a myocardial infarction (MI) is poorly documented...
  10. ncbi Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis
    M R Law
    Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, University of London, London EC1M 6BQ
    BMJ 326:1423. 2003
    ..To determine by how much statins reduce serum concentrations of low density lipoprotein (LDL) cholesterol and incidence of ischaemic heart disease (IHD) events and stroke, according to drug, dose, and duration of treatment...
  11. ncbi Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials
    M R Law
    Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, University of London, London EC1M 6BQ
    BMJ 326:1427. 2003
    ....
  12. ncbi The performance of blood pressure and other cardiovascular risk factors as screening tests for ischaemic heart disease and stroke
    M R Law
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ
    J Med Screen 11:3-7. 2004
    ..Among persons with no history of cardiovascular disease, age is a better screening test than the reversible risk factors, and the best policy is to offer treatment to all persons above a specified age such as 55 years...
  13. ncbi Folic acid, homocysteine, and cardiovascular disease: judging causality in the face of inconclusive trial evidence
    David S Wald
    Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary's School of Medicine and Dentistry, London EC1M 6BQ
    BMJ 333:1114-7. 2006
  14. ncbi Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials
    David S Wald
    Wolfson Institute of Preventive Medicine at Barts and The London Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London, United Kingdom
    Am J Med 122:290-300. 2009
    ....
  15. ncbi Environmental tobacco smoke and ischemic heart disease
    Malcolm R Law
    Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary's School of Medicine and Dentistry, University of London, London, UK
    Prog Cardiovasc Dis 46:31-8. 2003
    ..In experimental studies passive and active smoking have similar effects on platelet aggregation. The collective evidence supports a significant effect of low dose tobacco smoke exposure in causing ischaemic heart disease...
  16. ncbi A 16-week, randomized, double-blind, placebo-controlled, crossover trial to quantify the combined effect of an angiotensin-converting enzyme inhibitor and a beta-blocker on blood pressure reduction
    David S Wald
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, University of London, London, United Kingdom
    Clin Ther 30:2030-9. 2008
    ..Although beta-blockers and angiotensin-converting enzyme (ACE) inhibitors are often used together, there is a lack of quantitative evidence for the efficacy of this combination in reducing blood pressure (BP)...
  17. ncbi The dose-response relation between serum homocysteine and cardiovascular disease: implications for treatment and screening
    David S Wald
    Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1 M 6BQ, UK
    Eur J Cardiovasc Prev Rehabil 11:250-3. 2004
    ..It is uncertain whether treatment is best directed at those with high homocysteine or those at high risk irrespective of initial homocysteine...
  18. ncbi Blood pressure and the global burden of disease 2000. Part II: estimates of attributable burden
    Carlene M M Lawes
    Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand
    J Hypertens 24:423-30. 2006
    ..To provide estimates of the global burden of disease attributable to non-optimal blood pressure by age and sex for adults aged > or = 30 years, by WHO subregion...
  19. ncbi Blood pressure and the global burden of disease 2000. Part 1: estimates of blood pressure levels
    Carlene M M Lawes
    Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand
    J Hypertens 24:413-22. 2006
    ..To provide global estimates of blood pressure by age and sex for adults aged > or = 30 years, by WHO subregion...