Roger Corder

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. ncbi request reprint Comparison of red wine extract and polyphenol constituents on endothelin-1 synthesis by cultured endothelial cells
    Noorafza Q Khan
    William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, U K
    Clin Sci (Lond) 103:72S-75S. 2002
  2. doi request reprint Red wine, chocolate and vascular health: developing the evidence base
    Roger Corder
    Heart 94:821-3. 2008
  3. ncbi request reprint The procyanidin-induced pseudo laminar shear stress response: a new concept for the reversal of endothelial dysfunction
    Roger Corder
    William Harvey Research Institute, Barts and The London, Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Clin Sci (Lond) 107:513-7. 2004
  4. doi request reprint Regulation of vascular endothelial function by procyanidin-rich foods and beverages
    Paul W Caton
    Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK
    J Agric Food Chem 58:4008-13. 2010
  5. ncbi request reprint Homocysteine-induced endothelin-1 release is dependent on hyperglycaemia and reactive oxygen species production in bovine aortic endothelial cells
    Amarjit S Sethi
    Department of Experimental Therapeutics, William Harvey Research Institute, London, UK
    J Vasc Res 43:175-83. 2006
  6. doi request reprint Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism
    Paul W Caton
    Department of Translational Medicine and Therapeutics, Bart s and The London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, UK
    J Endocrinol 208:273-83. 2011
  7. ncbi request reprint A role for increased mRNA stability in the induction of endothelin-1 synthesis by lipopolysaccharide
    Julie A Douthwaite
    Department of Experimental Therapeutics, William Harvey Research Institute, St Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, EC1M 6BQ, London, UK
    Biochem Pharmacol 66:589-94. 2003
  8. doi request reprint Metformin suppresses hepatic gluconeogenesis through induction of SIRT1 and GCN5
    Paul W Caton
    Bart s and The London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University, London, UK
    J Endocrinol 205:97-106. 2010
  9. ncbi request reprint Factor VIIa stimulates endothelin-1 synthesis in TNF-primed endothelial cells by activation of protease-activated receptor 2
    Amarjit S Sethi
    Department of Experimental Therapeutics, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Clin Sci (Lond) 108:255-63. 2005
  10. doi request reprint Endotoxin induced hyperlactatemia and hypoglycemia is linked to decreased mitochondrial phosphoenolpyruvate carboxykinase
    Paul W Caton
    William Harvey Research Institute, Bart s and The London, Queen Mary s School of Medicine and Dentistry, London EC1M 6BQ, United Kingdom
    Life Sci 84:738-44. 2009

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Comparison of red wine extract and polyphenol constituents on endothelin-1 synthesis by cultured endothelial cells
    Noorafza Q Khan
    William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, U K
    Clin Sci (Lond) 103:72S-75S. 2002
    ..Thus inhibition of endothelin-1 synthesis by red wine may reduce the development of atherosclerosis, and hence decrease coronary heart disease...
  2. doi request reprint Red wine, chocolate and vascular health: developing the evidence base
    Roger Corder
    Heart 94:821-3. 2008
  3. ncbi request reprint The procyanidin-induced pseudo laminar shear stress response: a new concept for the reversal of endothelial dysfunction
    Roger Corder
    William Harvey Research Institute, Barts and The London, Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Clin Sci (Lond) 107:513-7. 2004
    ....
  4. doi request reprint Regulation of vascular endothelial function by procyanidin-rich foods and beverages
    Paul W Caton
    Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK
    J Agric Food Chem 58:4008-13. 2010
    ..Future investigations of procyanidin-rich products should assess the role KLF2 induction plays in the beneficial vascular effects of high flavonoid consumption...
  5. ncbi request reprint Homocysteine-induced endothelin-1 release is dependent on hyperglycaemia and reactive oxygen species production in bovine aortic endothelial cells
    Amarjit S Sethi
    Department of Experimental Therapeutics, William Harvey Research Institute, London, UK
    J Vasc Res 43:175-83. 2006
    ..The objective of this study was to investigate whether Hcy either alone or in high glucose conditions induces endothelin-1 (ET-1) synthesis via the production of reactive oxygen species (ROS)...
  6. doi request reprint Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism
    Paul W Caton
    Department of Translational Medicine and Therapeutics, Bart s and The London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, UK
    J Endocrinol 208:273-83. 2011
    ..These results highlight the need for a greater understanding of the role of SIRT1 in metabolic regulation and indicate the potential for adverse effects of SIRT1 activators if used therapeutically...
  7. ncbi request reprint A role for increased mRNA stability in the induction of endothelin-1 synthesis by lipopolysaccharide
    Julie A Douthwaite
    Department of Experimental Therapeutics, William Harvey Research Institute, St Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, EC1M 6BQ, London, UK
    Biochem Pharmacol 66:589-94. 2003
    ..These effects of LPS on mRNA stability may be a key mechanism in vascular pathologies through which many proteins are induced in response to infection...
  8. doi request reprint Metformin suppresses hepatic gluconeogenesis through induction of SIRT1 and GCN5
    Paul W Caton
    Bart s and The London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University, London, UK
    J Endocrinol 205:97-106. 2010
    ..In conclusion, induction of GCN5 and SIRT1 potentially represents a critical mechanism of action of metformin. In addition, these data identify induction of hepatic GCN5 as a potential therapeutic strategy for treatment of T2DM...
  9. ncbi request reprint Factor VIIa stimulates endothelin-1 synthesis in TNF-primed endothelial cells by activation of protease-activated receptor 2
    Amarjit S Sethi
    Department of Experimental Therapeutics, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Clin Sci (Lond) 108:255-63. 2005
    ..In summary, FVIIa can stimulate ET-1 synthesis in endothelial cells by activating PAR2, demonstrating a potential link between thrombotic processes and endothelial cell dysfunction...
  10. doi request reprint Endotoxin induced hyperlactatemia and hypoglycemia is linked to decreased mitochondrial phosphoenolpyruvate carboxykinase
    Paul W Caton
    William Harvey Research Institute, Bart s and The London, Queen Mary s School of Medicine and Dentistry, London EC1M 6BQ, United Kingdom
    Life Sci 84:738-44. 2009
    ..Previous studies of gluconeogenesis in endotoxemia have focused solely on PCK1. We investigated the relative roles of the two isoforms in hepatic and renal gluconeogenesis in a rat model of endotoxic shock, and in cultured hepatocytes...
  11. ncbi request reprint New hope for the treatment of diabetic complications
    Roger Corder
    William Harvey Research Institute, Barts and The London, Queen Mary s School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, U K
    Clin Sci (Lond) 103:323-4. 2002
  12. ncbi request reprint Evaluation of endothelin-converting enzyme inhibitors using cultured cells
    Roger Corder
    Department of Experimental Therapeutics, William Harvey Research Institute, St Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Methods Mol Biol 206:147-64. 2002
  13. ncbi request reprint Quantitative measurement of mRNA levels by RT-PCR. Studies of ECE-1 isoforms
    Delphine M Lees
    Department of Experimental Therapeutics, William Harvey Research Institute, St Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Methods Mol Biol 206:125-45. 2002
  14. ncbi request reprint Inhibitory effect of adrenomedullin on basal and tumour necrosis factor alpha-stimulated endothelin-1 synthesis in bovine aortic endothelial cells is independent of cyclic AMP
    Stewart Barker
    The William Harvey Research Institute, St Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary, University of London, EC1M 6BQ, London, UK
    Biochem Pharmacol 63:149-56. 2002
    ..The high sensitivity of this inhibition implicates ADM as an important physiological regulator of endothelial ET-1 production...