Dianne Cooper

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. ncbi request reprint Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow
    Dianne Cooper
    William Harvey Research Institute, Barts and The London, School of Medicine and Dentistry, Charterhouse Square, London, UK
    J Leukoc Biol 83:1459-66. 2008
  2. doi request reprint The effect of galectins on leukocyte trafficking in inflammation: sweet or sour?
    Dianne Cooper
    William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, United Kingdom
    Ann N Y Acad Sci 1253:181-92. 2012
  3. ncbi request reprint Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization
    Samia Yazid
    William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, United Kingdom
    Arterioscler Thromb Vasc Biol 30:1718-24. 2010
  4. ncbi request reprint Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature
    Magali Pederzoli-Ribeil
    William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK
    Blood 116:4288-96. 2010
  5. ncbi request reprint Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles
    Jesmond Dalli
    The William Harvey Research Institute, Barts and the London Medical School, London, United Kingdom
    Blood 112:2512-9. 2008
  6. pmc Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect
    Asif J Iqbal
    The William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom
    Am J Pathol 178:1201-9. 2011
  7. pmc Endogenous galectin-1 exerts tonic inhibition on experimental arthritis
    Asif J Iqbal
    William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom
    J Immunol 191:171-7. 2013
  8. doi request reprint Endogenous galectins and the control of the host inflammatory response
    Lucy V Norling
    Barts and the London School of Medicine, The William Harvey Research Institute, Centre for Biochemical Pharmacology, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
    J Endocrinol 201:169-84. 2009
  9. pmc Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes
    Suchita Nadkarni
    William Harvey Research Institute, Barts, United Kingdom
    Arterioscler Thromb Vasc Biol 31:2749-59. 2011
  10. ncbi request reprint Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow
    Paula Urquhart
    William Harvey Research Institute, London, UK
    J Pharmacol Exp Ther 321:656-62. 2007

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow
    Dianne Cooper
    William Harvey Research Institute, Barts and The London, School of Medicine and Dentistry, Charterhouse Square, London, UK
    J Leukoc Biol 83:1459-66. 2008
    ..These findings indicate that Gal-1 functions to limit neutrophil recruitment onto a TNF-treated endothelium, a property that may underline its inhibitory effects in acute inflammation...
  2. doi request reprint The effect of galectins on leukocyte trafficking in inflammation: sweet or sour?
    Dianne Cooper
    William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, United Kingdom
    Ann N Y Acad Sci 1253:181-92. 2012
    ..A better understanding of the function of this family of endogenous lectins will open new avenues for innovative drug discovery...
  3. ncbi request reprint Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization
    Samia Yazid
    William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, United Kingdom
    Arterioscler Thromb Vasc Biol 30:1718-24. 2010
    ..To determine whether the inhibitory action of the antiallergic cromone "mast cell stabilizing" drugs on polymorphonuclear leukocyte (PMN) trafficking is mediated through an annexin-A1 (Anx-A1) dependent mechanism...
  4. ncbi request reprint Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature
    Magali Pederzoli-Ribeil
    William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK
    Blood 116:4288-96. 2010
    ....
  5. ncbi request reprint Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles
    Jesmond Dalli
    The William Harvey Research Institute, Barts and the London Medical School, London, United Kingdom
    Blood 112:2512-9. 2008
    ....
  6. pmc Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect
    Asif J Iqbal
    The William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom
    Am J Pathol 178:1201-9. 2011
    ..Collectively, these data indicate that the absence of endogenous Gal-1 results in an abrogated response during the second phase of the edema reaction...
  7. pmc Endogenous galectin-1 exerts tonic inhibition on experimental arthritis
    Asif J Iqbal
    William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom
    J Immunol 191:171-7. 2013
    ..We have also highlighted the importance of endogenous Gal-1 in regulating T cell reactivity during experimental arthritis...
  8. doi request reprint Endogenous galectins and the control of the host inflammatory response
    Lucy V Norling
    Barts and the London School of Medicine, The William Harvey Research Institute, Centre for Biochemical Pharmacology, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
    J Endocrinol 201:169-84. 2009
    ..Gal-1, Gal-3 and Gal-9 are emerging as pertinent players in the modulation of acute and chronic inflammatory diseases, autoimmunity and cancer, and thus being increasingly recognised as molecular targets for innovative drug discovery...
  9. pmc Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes
    Suchita Nadkarni
    William Harvey Research Institute, Barts, United Kingdom
    Arterioscler Thromb Vasc Biol 31:2749-59. 2011
    ..In the present study, we addressed whether estrogen could activate vasculoprotective mechanisms via annexin A1 (AnxA1) mobilization in human polymorphonuclear cells (PMNs)...
  10. ncbi request reprint Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow
    Paula Urquhart
    William Harvey Research Institute, London, UK
    J Pharmacol Exp Ther 321:656-62. 2007
    ..In conclusion, we have reported that CORM-3 possesses acute anti-inflammatory effects in vivo and that these are probably the result of targeting PMN activation and rolling upon the endothelium...
  11. ncbi request reprint Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking
    Lucy V Norling
    The William Harvey Research Institute, Barts, and The London, Charterhouse Square, London EC1M 6BQ, UK
    FASEB J 22:682-90. 2008
    ..In conclusion, mimicking endothelial Gal-1 actions would be a novel strategy for controlling aberrant T-cell trafficking, hence for the development of innovative anti-inflammatory therapeutics...
  12. pmc The peritoneal tumour microenvironment of high-grade serous ovarian cancer
    D Andrew Leinster
    Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M6BQ, UK
    J Pathol 227:136-45. 2012
    ..We conclude that the multiple peritoneal tumour deposits found in HGSC patients can be modelled in the mouse. The techniques described here may be useful for assessing treatments that target the disseminated stage of this disease...
  13. ncbi request reprint Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate
    Dianne Cooper
    The William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom
    Methods Enzymol 480:199-244. 2010
    ....
  14. ncbi request reprint Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement
    Richard P G Hayhoe
    Centre for Biochemical Pharmacology, The William Harvey Research Institute, London, United Kingdom
    Blood 107:2123-30. 2006
    ..These findings demonstrate for the first time distinct mechanisms of action for ANXA1 and its N-terminal peptide Ac2-26...
  15. pmc 15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation
    Mark J Paul-Clark
    Department of Biochemical Pharmacology, William Harvey Research Institute, St Bartholomew s Hospital and the Royal London School of Medicine and Dentistry, Charterhouse Sq, London EC1M 6BQ, England, UK
    J Exp Med 200:69-78. 2004
    ..This aspirin-elicited NO exerts antiinflammatory effects in the microcirculation by inhibiting leukocyte-endothelium interactions...
  16. pmc Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation
    Hongmei Fu
    Centre for Biochemical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
    Nat Commun 5:3436. 2014
    ..We also show that, once in the tissue, Tregs inhibit Teff recruitment, further enabling a Teff:Treg ratio optimal for regulation. ..
  17. ncbi request reprint Angiotensin II type 1 receptors and the intestinal microvascular dysfunction induced by ischemia and reperfusion
    Thomas Petnehazy
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, 71130, USA
    Am J Physiol Gastrointest Liver Physiol 290:G1203-10. 2006
    ....
  18. ncbi request reprint Platelet-vessel wall interactions in the microcirculation
    Anitaben Tailor
    Department of Molecular and Cellular Physiology, Louisiana State University Health Science Center, Shreveport, 71130, USA
    Microcirculation 12:275-85. 2005
    ..The interactions between platelets and the walls of microscopic blood vessels appear to have important implications in the initiation and/or progression of tissue injury associated with different experimental models of human disease...
  19. ncbi request reprint Platelet-leukocyte-endothelial cell interactions after middle cerebral artery occlusion and reperfusion
    Mami Ishikawa
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130 3932, USA
    J Cereb Blood Flow Metab 24:907-15. 2004
    ..These findings implicate a major role for both platelet-associated and endothelial cell-associated P-selectin, as well as neutrophils in the inflammatory and prothrombogenic responses in the microcirculation after focal cerebral I/R...
  20. ncbi request reprint Leukocyte dependence of platelet adhesion in postcapillary venules
    Dianne Cooper
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130 3932, USA
    Am J Physiol Heart Circ Physiol 286:H1895-900. 2004
    ..These results are consistent with leukocytes playing a major role in supporting I/R-induced platelet adhesion...
  21. ncbi request reprint Molecular determinants of the prothrombogenic and inflammatory phenotype assumed by the postischemic cerebral microcirculation
    Mami Ishikawa
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, 1501 Kings Hwy, Shreveport, LA 71130 3932, USA
    Stroke 34:1777-82. 2003
    ..The objective of this study was to define the magnitude and molecular determinants of the platelet- and leukocyte-endothelial cell adhesive interactions induced by I/R in the mouse brain...
  22. ncbi request reprint Oxidative stress promotes blood cell-endothelial cell interactions in the microcirculation
    Dianne Cooper
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, LA 71130 3932, USA
    Cardiovasc Toxicol 2:165-80. 2002
    ....
  23. ncbi request reprint Superoxide mediates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules
    Wolfgang H Cerwinka
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport 71130 3932, USA
    Am J Physiol Heart Circ Physiol 284:H535-41. 2003
    ..These findings indicate that neutrophil-derived superoxide plays a major role in the modulation of endotoxin-induced P/E adhesion...
  24. ncbi request reprint Nitric oxide modulates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules
    Wolfgang H Cerwinka
    Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130 3932, USA
    Am J Physiol Heart Circ Physiol 282:H1111-7. 2002
    ..These findings indicate that 1) eNOS-derived NO attenuates endotoxin-induced P/E adhesion and 2) sGC is responsible for the antiadhesive action of NO...