Deborah Ashby

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. ncbi request reprint Bayesian statistics in medicine: a 25 year review
    Deborah Ashby
    Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, University of London, Charterhouse Square, London EC1M 6BQ, UK
    Stat Med 25:3589-631. 2006
  2. pmc TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: a randomised controlled trial with patient preference study. [ISRCTN79353052]
    Pamela L Cross
    Centre for Health Sciences, Barts and The London, Queen Mary s School of Medicine and Dentistry, Whitechapel, London E1 2AT, UK
    BMC Musculoskelet Disord 6:55. 2005
  3. pmc Managing Injuries of the Neck Trial (MINT): design of a randomised controlled trial of treatments for whiplash associated disorders
    Sarah E Lamb
    Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
    BMC Musculoskelet Disord 8:7. 2007
  4. ncbi request reprint Where's the utility in Bayesian data-monitoring of clinical trials?
    Deborah Ashby
    Wolfson Institute of Preventive Medicine, Queen Mary, University of London, London, UK
    Clin Trials 2:197-205; discussion 205-8. 2005
  5. doi request reprint Establishing causality in the assessment of safety of medicines for children
    Deborah Ashby
    Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Acta Paediatr 97:1611-6. 2008
  6. pmc Advice to use topical or oral ibuprofen for chronic knee pain in older people: randomised controlled trial and patient preference study
    Martin Underwood
    Centre for Health Sciences, Barts and The London, Queen Mary, University of London, London E1 2AT
    BMJ 336:138-42. 2008
  7. ncbi request reprint A systematic review of pain drawing literature: should pain drawings be used for psychologic screening?
    Dawn Carnes
    Institute of Health Sciences Education, Barts and The London, Queen Mary s School of Medicine and Dentistry, London, UK
    Clin J Pain 22:449-57. 2006
  8. ncbi request reprint Sample size for cluster randomized trials: effect of coefficient of variation of cluster size and analysis method
    Sandra M Eldridge
    Centre for Health Sciences, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK
    Int J Epidemiol 35:1292-300. 2006
  9. ncbi request reprint Lessons for cluster randomized trials in the twenty-first century: a systematic review of trials in primary care
    Sandra M Eldridge
    Centre for General Practice and Primary Care, Institute of Community Health Sciences, Bar and the London, Queen Mary, University of London, Mile End Road, London E1 4NS, UK
    Clin Trials 1:80-90. 2004
  10. pmc Chronic fatigue syndrome in an ethnically diverse population: the influence of psychosocial adversity and physical inactivity
    Kamaldeep S Bhui
    Centre for Psychiatry, Wolson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    BMC Med 9:26. 2011

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Bayesian statistics in medicine: a 25 year review
    Deborah Ashby
    Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, University of London, Charterhouse Square, London EC1M 6BQ, UK
    Stat Med 25:3589-631. 2006
    ....
  2. pmc TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: a randomised controlled trial with patient preference study. [ISRCTN79353052]
    Pamela L Cross
    Centre for Health Sciences, Barts and The London, Queen Mary s School of Medicine and Dentistry, Whitechapel, London E1 2AT, UK
    BMC Musculoskelet Disord 6:55. 2005
    ..Patient preferences may influence the comparative effectiveness of drugs delivered via different routes...
  3. pmc Managing Injuries of the Neck Trial (MINT): design of a randomised controlled trial of treatments for whiplash associated disorders
    Sarah E Lamb
    Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
    BMC Musculoskelet Disord 8:7. 2007
    ..use of The Whiplash Book versus usual advice when patients first attend the emergency department; 2. referral to physiotherapy versus reinforcement of advice for patients with continuing symptoms at three weeks...
  4. ncbi request reprint Where's the utility in Bayesian data-monitoring of clinical trials?
    Deborah Ashby
    Wolfson Institute of Preventive Medicine, Queen Mary, University of London, London, UK
    Clin Trials 2:197-205; discussion 205-8. 2005
    ..A natural statistical framework for evidence-based medicine is a Bayesian approach to decision-making that incorporates an integrated summary of the available evidence and associated uncertainty with assessment of utilities...
  5. doi request reprint Establishing causality in the assessment of safety of medicines for children
    Deborah Ashby
    Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Acta Paediatr 97:1611-6. 2008
    ..Data on safety of medicines in children typically arises from various sources, rendering assessment of causality challenging...
  6. pmc Advice to use topical or oral ibuprofen for chronic knee pain in older people: randomised controlled trial and patient preference study
    Martin Underwood
    Centre for Health Sciences, Barts and The London, Queen Mary, University of London, London E1 2AT
    BMJ 336:138-42. 2008
    ..To determine whether older patients with chronic knee pain should be advised to use topical or oral non-steroidal anti-inflammatory drugs (NSAIDs)...
  7. ncbi request reprint A systematic review of pain drawing literature: should pain drawings be used for psychologic screening?
    Dawn Carnes
    Institute of Health Sciences Education, Barts and The London, Queen Mary s School of Medicine and Dentistry, London, UK
    Clin J Pain 22:449-57. 2006
    ..We systematically reviewed the literature that directly compared pain drawing scoring systems with measures of psychologic state...
  8. ncbi request reprint Sample size for cluster randomized trials: effect of coefficient of variation of cluster size and analysis method
    Sandra M Eldridge
    Centre for Health Sciences, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK
    Int J Epidemiol 35:1292-300. 2006
    ..This can affect trial power, but standard sample size formulae for these trials ignore this. Previous studies addressing this issue have mostly focused on continuous outcomes or methods that are sometimes difficult to use in practice...
  9. ncbi request reprint Lessons for cluster randomized trials in the twenty-first century: a systematic review of trials in primary care
    Sandra M Eldridge
    Centre for General Practice and Primary Care, Institute of Community Health Sciences, Bar and the London, Queen Mary, University of London, Mile End Road, London E1 4NS, UK
    Clin Trials 1:80-90. 2004
    ..There is little recent research on the methodologic quality of cluster randomized trials and none focuses on primary health care where these trials are increasingly common...
  10. pmc Chronic fatigue syndrome in an ethnically diverse population: the influence of psychosocial adversity and physical inactivity
    Kamaldeep S Bhui
    Centre for Psychiatry, Wolson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    BMC Med 9:26. 2011
    ..This paper reports the prevalence of chronic fatigue (CF) and CFS in an ethnically diverse population sample and tests whether prevalence varies by social adversity, social support, physical inactivity, anxiety and depression...
  11. ncbi request reprint Lack of effect of influenza immunisation on anticoagulant control in patients on long-term warfarin
    Peter MacCallum
    Department of Haematology, Barts and The London NHS Trust, London, UK
    Pharmacoepidemiol Drug Saf 16:786-9. 2007
    ..We therefore prospectively evaluated the effect of influenza vaccination on International Normalised Ratio (INR) control in patients on long-term warfarin...
  12. pmc Internal and external validity of cluster randomised trials: systematic review of recent trials
    Sandra Eldridge
    Centre for Health Sciences, Barts and the London School of Medicine and Dentistry, London E1 2AT
    BMJ 336:876-80. 2008
    ..To assess aspects of the internal validity of recently published cluster randomised trials and explore the reporting of information useful in assessing the external validity of these trials...
  13. doi request reprint A systematic review of chronic fatigue, its syndromes and ethnicity: prevalence, severity, co-morbidity and coping
    Sokratis Dinos
    Centre for Psychiatry, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Int J Epidemiol 38:1554-70. 2009
    ..If there are convincing differences in prevalence and risk factors across all or some ethnic groups, investigating the causes of these can help unravel the pathophysiology of CFS...
  14. ncbi request reprint Thrombosis prevention trial: compliance with warfarin treatment and investigation of a retained effect
    Alicja R Rudnicka
    Department of Environmental and Preventive Medicine, Medical Research Council Epidemiology and Medical Care Unit, Wolfson Institute of Preventive Medicine, London, England
    Arch Intern Med 163:1454-60. 2003
    ..This article examines compliance (duration of treatment) with warfarin treatment and whether warfarin has a retained effect...
  15. ncbi request reprint Smooth muscle cholinergic denervation hypersensitivity in diverticular disease
    Mark Golder
    Academic Department of Surgery, Barts and the London School of Medicine and Dentistry, Whitechapel, London, UK
    Lancet 361:1945-51. 2003
    ..We aimed to investigate the role of smooth muscle and neural cholinergic activity in the pathogenesis of this disease...
  16. pmc Financial incentives to improve adherence to anti-psychotic maintenance medication in non-adherent patients - a cluster randomised controlled trial (FIAT)
    Stefan Priebe
    Unit for Social and Community Psychiatry, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Newham Centre for Mental Health, London, UK
    BMC Psychiatry 9:61. 2009
    ....
  17. ncbi request reprint Informed patient consent to participation in cluster randomized trials: an empirical exploration of trials in primary care
    Sandra M Eldridge
    Centre for General Practice and Primary Care, Institute of Community Health Sciences, Queen Mary, University of London, UK
    Clin Trials 2:91-8. 2005
    ..A more public debate may clarify the general acceptability of not obtaining consent in certain situations...
  18. ncbi request reprint Variations in primary open-angle glaucoma prevalence by age, gender, and race: a Bayesian meta-analysis
    Alicja R Rudnicka
    Division of Community Health Sciences, St George s, University of London, UK
    Invest Ophthalmol Vis Sci 47:4254-61. 2006
    ..To quantify the variation in primary open-angle glaucoma (OAG) prevalence with age, gender, race, year of publication, and survey methodology...
  19. pmc Oral protein energy supplements for children with cystic fibrosis: CALICO multicentre randomised controlled trial
    Vanessa J Poustie
    University of Liverpool Division of Child Health, Royal Liverpool Children s Hospital, Liverpool L12 2AP
    BMJ 332:632-6. 2006
    ..To determine whether oral protein energy supplements, used long term in children with cystic fibrosis who are moderately malnourished, improve nutritional and other outcomes...
  20. ncbi request reprint High prevalence but low impact of data extraction and reporting errors were found in Cochrane systematic reviews
    Ashley P Jones
    Alder Hey Children s Hospital, The University of Liverpool, Institute of Child Health, Eaton Road, Liverpool, L12 2AP, England
    J Clin Epidemiol 58:741-2. 2005
    ..Incorrect data extraction can lead to false conclusions. The objective of this study was to retrospectively repeat the data extraction in all systematic reviews conducted by the Cochrane Cystic Fibrosis and Genetic Disorders Group...
  21. ncbi request reprint Attenuated Salmonella typhimurium SL3261 as a vaccine vector for recombinant antigen in rabbits
    Deborah Ashby
    Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada
    J Immunol Methods 299:153-64. 2005
    ..ducreyi infection, and is suitable for pre-clinical evaluation of Salmonella vector-based H. ducreyi vaccine antigen candidates...
  22. pmc Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: nested case-control study
    Carlos Martinez
    General Practice Research Database Division, Medicines and Healthcare products Regulatory Agency, London SW8 5NQ
    BMJ 330:389. 2005
    ....
  23. pmc Selective serotonin reuptake inhibitors (SSRIs) and suicide in adults: meta-analysis of drug company data from placebo controlled, randomised controlled trials submitted to the MHRA's safety review
    David Gunnell
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 330:385. 2005
    ..To investigate whether selective serotonin reuptake inhibitor (SSRI) antidepressants are associated with an increased risk of suicide related outcomes in adults...
  24. pmc Systematic reviews and lifelong diseases
    Heather E Elphick
    University of Liverpool Institute of Child Health, Alder Hey Children s Hospital, Liverpool L12 2AP
    BMJ 325:381-4. 2002
  25. ncbi request reprint Diet and colorectal cancer: an investigation of the lectin/galactose hypothesis
    Richard C Evans
    Department of Medicine, University of Liverpool, England
    Gastroenterology 122:1784-92. 2002
    ..This study tests the hypothesis that galactose, which is variably plentiful in fruit and vegetable but not cereal fibers, might prevent cancer by binding and inhibiting such lectins...