Scott A Akker

Summary

Affiliation: Queen Mary
Country: UK

Publications

  1. ncbi request reprint Pre-spliceosomal binding of U1 small nuclear ribonucleoprotein (RNP) and heterogenous nuclear RNP E1 is associated with suppression of a growth hormone receptor pseudoexon
    Scott A Akker
    Department of Endocrinology, 5th Floor, King George V Block, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, United Kingdom
    Mol Endocrinol 21:2529-40. 2007
  2. doi request reprint Long-term remission and recurrence rates in Cushing's disease: predictive factors in a single-centre study
    Krystallenia I Alexandraki
    Department of Endocrinology, St Bartholomew s Hospital, Barts and The London NHS Trust, Barts and the London School of Medicine, London, UK
    Eur J Endocrinol 168:639-48. 2013
  3. doi request reprint Contrasting clinical manifestations of SDHB and VHL associated chromaffin tumours
    Umasuthan Srirangalingam
    Department of Endocrinology, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    Endocr Relat Cancer 16:515-25. 2009
  4. doi request reprint A prospective evaluation of postural stimulation testing, computed tomography and adrenal vein sampling in the differential diagnosis of primary aldosteronism
    Jeshen H G Lau
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 76:182-8. 2012
  5. doi request reprint The prevalence and characteristic features of cyclicity and variability in Cushing's disease
    Krystallenia I Alexandraki
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, UK
    Eur J Endocrinol 160:1011-8. 2009
  6. doi request reprint Assessment of serum-free cortisol levels in patients with adrenocortical carcinoma treated with mitotane: a pilot study
    Krystallenia I Alexandraki
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 72:305-11. 2010
  7. doi request reprint Clinical manifestations of familial paraganglioma and phaeochromocytomas in succinate dehydrogenase B (SDH-B) gene mutation carriers
    Umasuthan Srirangalingam
    Department of Endocrinology, St Bartholomew s Hospital, West Smithfield, London, UK
    Clin Endocrinol (Oxf) 69:587-96. 2008
  8. doi request reprint Diagnosis and localisation of insulinoma: the value of modern magnetic resonance imaging in conjunction with calcium stimulation catheterisation
    Maralyn R Druce
    Department of Endocrinology, Barts and the London Medical School, St Bartholomew s Hospital, London, UK
    Eur J Endocrinol 162:971-8. 2010
  9. ncbi request reprint Putting some spine into alternative splicing
    Bernard Khoo
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, UK
    Trends Biotechnol 21:328-30. 2003
  10. doi request reprint Evaluation of an enzyme immunoassay for plasma-free metanephrines in the diagnosis of catecholamine-secreting tumors
    Michel Procopiou
    Department of Endocrinology, St Bartholomew s Hospital, West Smithfield, London EC1A7BE, UK
    Eur J Endocrinol 161:131-40. 2009

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Pre-spliceosomal binding of U1 small nuclear ribonucleoprotein (RNP) and heterogenous nuclear RNP E1 is associated with suppression of a growth hormone receptor pseudoexon
    Scott A Akker
    Department of Endocrinology, 5th Floor, King George V Block, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, United Kingdom
    Mol Endocrinol 21:2529-40. 2007
    ..Immunoprecipitation experiments with three other pseudoexons suggested that pre-spliceosomal binding of U1 snRNP is a potential general mechanism of suppression of pseudoexons...
  2. doi request reprint Long-term remission and recurrence rates in Cushing's disease: predictive factors in a single-centre study
    Krystallenia I Alexandraki
    Department of Endocrinology, St Bartholomew s Hospital, Barts and The London NHS Trust, Barts and the London School of Medicine, London, UK
    Eur J Endocrinol 168:639-48. 2013
    ..To investigate the early and late outcomes of patients with Cushing's disease (CD) submitted to a neurosurgical procedure as first-line treatment...
  3. doi request reprint Contrasting clinical manifestations of SDHB and VHL associated chromaffin tumours
    Umasuthan Srirangalingam
    Department of Endocrinology, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    Endocr Relat Cancer 16:515-25. 2009
    ..VHL-related tumours tend to be adrenal phaeochromocytomas, frequently bilateral and associated with a milder phenotype...
  4. doi request reprint A prospective evaluation of postural stimulation testing, computed tomography and adrenal vein sampling in the differential diagnosis of primary aldosteronism
    Jeshen H G Lau
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 76:182-8. 2012
    ..Various series have reported the utility of postural stimulation testing (PST), cross-sectional imaging and adrenal vein sampling (AVS) in the assessment of PA, but most of these studies were retrospective...
  5. doi request reprint The prevalence and characteristic features of cyclicity and variability in Cushing's disease
    Krystallenia I Alexandraki
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, UK
    Eur J Endocrinol 160:1011-8. 2009
    ..The aim of the present study was to investigate the prevalence of cyclicity and variability in patients with Cushing's disease, and to identify putative distinctive features...
  6. doi request reprint Assessment of serum-free cortisol levels in patients with adrenocortical carcinoma treated with mitotane: a pilot study
    Krystallenia I Alexandraki
    Department of Endocrinology, St Bartholomew s Hospital, London, UK
    Clin Endocrinol (Oxf) 72:305-11. 2010
    ..Mitotane treatment in adrenocortical carcinoma (ACC) results in unreliable measurement of serum total cortisol (TC) levels because of an elevation in corticosteroid-binding globulin (CBG)...
  7. doi request reprint Clinical manifestations of familial paraganglioma and phaeochromocytomas in succinate dehydrogenase B (SDH-B) gene mutation carriers
    Umasuthan Srirangalingam
    Department of Endocrinology, St Bartholomew s Hospital, West Smithfield, London, UK
    Clin Endocrinol (Oxf) 69:587-96. 2008
    ..The aim of this study was to describe the clinical manifestations of subjects with SDH-B gene mutations...
  8. doi request reprint Diagnosis and localisation of insulinoma: the value of modern magnetic resonance imaging in conjunction with calcium stimulation catheterisation
    Maralyn R Druce
    Department of Endocrinology, Barts and the London Medical School, St Bartholomew s Hospital, London, UK
    Eur J Endocrinol 162:971-8. 2010
    ..Preoperative localisation of insulinoma improves cure rate and reduces complications, but may be challenging...
  9. ncbi request reprint Putting some spine into alternative splicing
    Bernard Khoo
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, UK
    Trends Biotechnol 21:328-30. 2003
    ..Two recent papers show that the defect in splicing of exon 7 of SMN2 is specifically corrected by small synthetic effectors. These new and specific approaches have potential in the treatment of diseases caused by defective splicing...
  10. doi request reprint Evaluation of an enzyme immunoassay for plasma-free metanephrines in the diagnosis of catecholamine-secreting tumors
    Michel Procopiou
    Department of Endocrinology, St Bartholomew s Hospital, West Smithfield, London EC1A7BE, UK
    Eur J Endocrinol 161:131-40. 2009
    ..To define the test characteristics of an enzyme immunoassay (EIA) for plasma-free metanephrines (metanephrine and normetanephrine) in the diagnosis of pheochromocytoma and paraganglioma...