D R Livingstone

Summary

Affiliation: Plymouth Marine Laboratory
Country: UK

Publications

  1. ncbi request reprint The fate of organic xenobiotics in aquatic ecosystems: quantitative and qualitative differences in biotransformation by invertebrates and fish
    D R Livingstone
    NERC Plymouth Marine Laboratory, Devon, UK
    Comp Biochem Physiol A Mol Integr Physiol 120:43-9. 1998
  2. ncbi request reprint Studies on biomarkers of copper exposure and toxicity in the marine amphipod Gammarus locusta (Crustacea): I. Induction of metallothionein and lipid peroxidation
    A D Correia
    IMAR Institute of Marine Research, Department of Environmental Sciences and Engineering, College of Sciences and Technology, Lisbon New University, 2829 516 Caparica, Portugal
    Biomarkers 7:422-37. 2002
  3. ncbi request reprint Development of hepatic CYP1A and blood vitellogenin in eel (Anguilla anguilla) for use as biomarkers in the Thames Estuary, UK
    D R Livingstone
    Centre for Coastal and Marine Sciences, Plymouth Marine Laboratory, Citadel Hill, Plymouth, Devon PL1 2PB, UK
    Mar Environ Res 50:367-71. 2000
  4. ncbi request reprint Increased potential for NAD(P)H-dependent reactive oxygen species production of hepatic subcellular fractions of fish species with in vivo exposure to contaminants
    D R Livingstone
    Centre for Coastal and Marine Sciences, Plymouth Marine Laboratory, Citadel Hill, Plymouth, Devon PL1 2PB, UK
    Mar Environ Res 50:57-60. 2000
  5. ncbi request reprint Hepatic 7-ethoxyresorufin O-deethylase activity in eel (Anguilla anguilla) from the Thames Estuary and comparisons with other United Kingdom Estuaries
    A Doyotte
    NERC Plymouth Marine Laboratory, Plymouth Devon, UK
    Mar Pollut Bull 42:1313-22. 2001
  6. ncbi request reprint Seasonal variation and estradiol-dependent elevation of Thames estuary eel Anguilla anguilla plasma vitellogenin levels and comparisons with other United Kingdom estuaries
    L D Peters
    Plymouth Marine Laboratory, UK
    Sci Total Environ 279:137-50. 2001
  7. ncbi request reprint Variation of antioxidant enzyme activities of sprat (Sprattus sprattus) larvae and organic contaminant levels in mixed zooplankton from the southern North Sea
    L D Peters
    NERC Plymouth Marine Laboratory, Devon, UK
    Mar Pollut Bull 42:1087-95. 2001
  8. ncbi request reprint Seasonal variation in cytochrome P450 immunopositive protein levels, lipid peroxidation and genetic toxicity in digestive gland of the mussel Mytilus edulis
    J P Shaw
    Plymouth Marine Laboratory, West Hoe, Devon, UK
    Aquat Toxicol 67:325-36. 2004
  9. ncbi request reprint Elevation of cytochrome P450-immunopositive protein and DNA damage in mussels (Mytilus edulis) transplanted to a contaminated site
    J P Shaw
    NERC Plymouth Marine Laboratory, Devon, UK
    Mar Environ Res 54:505-9. 2002
  10. ncbi request reprint NADPH-, NADH- and cumene hydroperoxide-dependent metabolism of benzo[a]pyrene by pyloric caeca microsomes of the sea star Asterias rubens L. (Echinodermata: Asteroidea)
    P J Den Besten
    NERC Plymouth Marine Laboratory, Citadel Hill, UK
    Xenobiotica 24:989-1001. 1994

Collaborators

Detail Information

Publications12

  1. ncbi request reprint The fate of organic xenobiotics in aquatic ecosystems: quantitative and qualitative differences in biotransformation by invertebrates and fish
    D R Livingstone
    NERC Plymouth Marine Laboratory, Devon, UK
    Comp Biochem Physiol A Mol Integr Physiol 120:43-9. 1998
    ....
  2. ncbi request reprint Studies on biomarkers of copper exposure and toxicity in the marine amphipod Gammarus locusta (Crustacea): I. Induction of metallothionein and lipid peroxidation
    A D Correia
    IMAR Institute of Marine Research, Department of Environmental Sciences and Engineering, College of Sciences and Technology, Lisbon New University, 2829 516 Caparica, Portugal
    Biomarkers 7:422-37. 2002
    ..It is concluded that MT and LP offer potential for application as biomarkers in G. locusta...
  3. ncbi request reprint Development of hepatic CYP1A and blood vitellogenin in eel (Anguilla anguilla) for use as biomarkers in the Thames Estuary, UK
    D R Livingstone
    Centre for Coastal and Marine Sciences, Plymouth Marine Laboratory, Citadel Hill, Plymouth, Devon PL1 2PB, UK
    Mar Environ Res 50:367-71. 2000
    ..mol. wt. (recognised by antibodies to vitellogenin of Morone saxatilis), but putative vitellogenin could not be detected in A. anguilla from selected sites in the Thames Estuary...
  4. ncbi request reprint Increased potential for NAD(P)H-dependent reactive oxygen species production of hepatic subcellular fractions of fish species with in vivo exposure to contaminants
    D R Livingstone
    Centre for Coastal and Marine Sciences, Plymouth Marine Laboratory, Citadel Hill, Plymouth, Devon PL1 2PB, UK
    Mar Environ Res 50:57-60. 2000
    ..Overall the data indicate increased potential for ROS production in liver of fish exposed to field pollution, and support the hypothesis of oxidative stress as a mechanism of contaminant-mediated disease in fish...
  5. ncbi request reprint Hepatic 7-ethoxyresorufin O-deethylase activity in eel (Anguilla anguilla) from the Thames Estuary and comparisons with other United Kingdom Estuaries
    A Doyotte
    NERC Plymouth Marine Laboratory, Plymouth Devon, UK
    Mar Pollut Bull 42:1313-22. 2001
    ..However, the highest level of EROD activity was observed in fish from the Weston Canal (Merseyside)...
  6. ncbi request reprint Seasonal variation and estradiol-dependent elevation of Thames estuary eel Anguilla anguilla plasma vitellogenin levels and comparisons with other United Kingdom estuaries
    L D Peters
    Plymouth Marine Laboratory, UK
    Sci Total Environ 279:137-50. 2001
    ..These results indicate inter-species variation between the plasma vitellogenin concentrations of A. anguilla and other published fish studies undertaken along the same estuaries...
  7. ncbi request reprint Variation of antioxidant enzyme activities of sprat (Sprattus sprattus) larvae and organic contaminant levels in mixed zooplankton from the southern North Sea
    L D Peters
    NERC Plymouth Marine Laboratory, Devon, UK
    Mar Pollut Bull 42:1087-95. 2001
    ..Larval antioxidant enzyme activities are discussed in relation to potential processes affecting them including plankton contaminant level distributions...
  8. ncbi request reprint Seasonal variation in cytochrome P450 immunopositive protein levels, lipid peroxidation and genetic toxicity in digestive gland of the mussel Mytilus edulis
    J P Shaw
    Plymouth Marine Laboratory, West Hoe, Devon, UK
    Aquat Toxicol 67:325-36. 2004
    ..The study highlights the need to establish the relative contribution of DNA damage and DNA repair processes to the production of DNA strand breaks and emphasises the need to consider seasonal variation in interpretation of biomarkers...
  9. ncbi request reprint Elevation of cytochrome P450-immunopositive protein and DNA damage in mussels (Mytilus edulis) transplanted to a contaminated site
    J P Shaw
    NERC Plymouth Marine Laboratory, Devon, UK
    Mar Environ Res 54:505-9. 2002
    ..8 fold greater (P < 0.05) than indigenous mussels at the transplant site. These changes were small but significant when compared to the observed temporal changes in the indigenous populations...
  10. ncbi request reprint NADPH-, NADH- and cumene hydroperoxide-dependent metabolism of benzo[a]pyrene by pyloric caeca microsomes of the sea star Asterias rubens L. (Echinodermata: Asteroidea)
    P J Den Besten
    NERC Plymouth Marine Laboratory, Citadel Hill, UK
    Xenobiotica 24:989-1001. 1994
    ..7. Incubations of pyloric caeca microsomes with BaP and a superoxide anion radical-generating system (xanthine/xanthine oxidase) produced putative protein adducts but no free metabolites...
  11. ncbi request reprint Immunochemical investigations of cytochrome P450 forms/epitopes (CYP1A, 2B, 2E, 3A and 4A) in digestive gland of Mytilus sp
    L D Peters
    NERC Plymouth Marine Laboratory, Citadel Hill, Plymouth, UK
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 121:361-9. 1998
    ..05), indicative of independent regulation of different CYP forms. Overall, the apparent molecular weight and field studies indicate at least five different digestive gland CYP forms...
  12. ncbi request reprint Effect of exposure to benzo[a]pyrene on SODs, CYP1A1/1A2- and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis
    M Monari
    Department of Biochemistry G Moruzzi, University of Bologna, Via Tolara di Sopra 50, 40064 Ozzano Emilia, Bologna, Italy
    Mar Environ Res 63:200-18. 2007
    ..Redox cycling of the diones may also have contributed to ROS production, leading to the increased SOD activities...