G D Perkins

Summary

Country: UK

Publications

  1. ncbi Kerbs von Lungren 6 antigen is a marker of alveolar inflammation but not of infection in patients with acute respiratory distress syndrome
    Nazim Nathani
    Lung Injury and Fibrosis Treatment Program, Department of Medical Sciences, The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Crit Care 12:R12. 2008
  2. ncbi Teaching recognition of agonal breathing improves accuracy of diagnosing cardiac arrest
    Gavin D Perkins
    Division of Medical Sciences, University of Birmingham, Lung Investigation Unit, Queen Elizabeth Hospital, Birmingham B15 2TT, UK
    Resuscitation 70:432-7. 2006
  3. ncbi The beta-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial
    Gavin D Perkins
    Department of Intensive Care Medicine, Birmingham Heartlands Hospital, UK
    Am J Respir Crit Care Med 173:281-7. 2006
  4. ncbi In-water resuscitation: a pilot evaluation
    Gavin D Perkins
    Division of Medical Sciences, University of Birmingham, Birmingham, UK
    Resuscitation 65:321-4. 2005
  5. ncbi Cardiopulmonary collapse associated with malpositioning of an adjustable flange tracheostomy tube
    Gavin D Perkins
    Department of Respiratory and Critical Care Medicine, University of Birmingham, Birmingham B15 2TT, United Kingdom
    Resuscitation 69:357-8. 2006
  6. ncbi Effects of a backboard, bed height, and operator position on compression depth during simulated resuscitation
    Gavin D Perkins
    University of Birmingham, Division of Medical Sciences, B15 2TT Birmingham, UK
    Intensive Care Med 32:1632-5. 2006
  7. ncbi CPREzy: an evaluation during simulated cardiac arrest on a hospital bed
    Gavin D Perkins
    Division of Medical Sciences, University of Birmingham, Birmingham B152TT, UK
    Resuscitation 64:103-8. 2005
  8. ncbi Simulation in resuscitation training
    Gavin D Perkins
    Warwick Medical School, University of Warwick, Coventry CV4 4AL, United Kingdom
    Resuscitation 73:202-11. 2007
  9. ncbi Advanced life support cardiac arrest scenario test evaluation
    Gavin D Perkins
    Warwick Medical School, University of Warwick, Warwick CV4 4AL, United Kingdom
    Resuscitation 75:484-90. 2007
  10. ncbi In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury
    G D Perkins
    Lung Investigation Unit, Nuffield House, Queen Elizabeth Hospital, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Thorax 62:36-42. 2007

Collaborators

Detail Information

Publications59

  1. ncbi Kerbs von Lungren 6 antigen is a marker of alveolar inflammation but not of infection in patients with acute respiratory distress syndrome
    Nazim Nathani
    Lung Injury and Fibrosis Treatment Program, Department of Medical Sciences, The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Crit Care 12:R12. 2008
    ..We hypothesized that the elevation of KL-6 in ARDS is dependent upon the severity of neutrophilic inflammation. Furthermore we were interested in the relationship between significant alveolar infection and KL-6 levels...
  2. ncbi Teaching recognition of agonal breathing improves accuracy of diagnosing cardiac arrest
    Gavin D Perkins
    Division of Medical Sciences, University of Birmingham, Lung Investigation Unit, Queen Elizabeth Hospital, Birmingham B15 2TT, UK
    Resuscitation 70:432-7. 2006
    ..The aim of this study was to test the hypothesis that specific tuition on agonal breathing improves the accuracy of checking for signs of circulation as a diagnostic test for cardiac arrest...
  3. ncbi The beta-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial
    Gavin D Perkins
    Department of Intensive Care Medicine, Birmingham Heartlands Hospital, UK
    Am J Respir Crit Care Med 173:281-7. 2006
    ..Experimental data suggest that manipulation of alveolar fluid clearance with beta-agonists can accelerate the resolution of alveolar edema and improve survival...
  4. ncbi In-water resuscitation: a pilot evaluation
    Gavin D Perkins
    Division of Medical Sciences, University of Birmingham, Birmingham, UK
    Resuscitation 65:321-4. 2005
    ..Recent studies have suggested that commencing resuscitative efforts with the victim still in the water may be beneficial. The aim of this pilot study was to evaluate the feasibility and efficacy of in-water unsupported rescue breathing...
  5. ncbi Cardiopulmonary collapse associated with malpositioning of an adjustable flange tracheostomy tube
    Gavin D Perkins
    Department of Respiratory and Critical Care Medicine, University of Birmingham, Birmingham B15 2TT, United Kingdom
    Resuscitation 69:357-8. 2006
  6. ncbi Effects of a backboard, bed height, and operator position on compression depth during simulated resuscitation
    Gavin D Perkins
    University of Birmingham, Division of Medical Sciences, B15 2TT Birmingham, UK
    Intensive Care Med 32:1632-5. 2006
    ..To investigate the effect of a backboard, cardiopulmonary resuscitation (CPR) provider body position and bed height on the quality of chest compression during simulated in-hospital resuscitation...
  7. ncbi CPREzy: an evaluation during simulated cardiac arrest on a hospital bed
    Gavin D Perkins
    Division of Medical Sciences, University of Birmingham, Birmingham B152TT, UK
    Resuscitation 64:103-8. 2005
    ..Further animal and clinical studies are required to validate this finding in vivo and to see if it translates to an improvement in outcome in human victims of cardiac arrest...
  8. ncbi Simulation in resuscitation training
    Gavin D Perkins
    Warwick Medical School, University of Warwick, Coventry CV4 4AL, United Kingdom
    Resuscitation 73:202-11. 2007
    ..The role of task trainers, high and low fidelity patient simulators and computer assisted simulation as teaching tools are discussed...
  9. ncbi Advanced life support cardiac arrest scenario test evaluation
    Gavin D Perkins
    Warwick Medical School, University of Warwick, Warwick CV4 4AL, United Kingdom
    Resuscitation 75:484-90. 2007
    ..The aim of this study was to establish equivalence between the four different CASTest scenarios and investigate the impact of profession, candidate order and course centre on the pass rate...
  10. ncbi In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury
    G D Perkins
    Lung Investigation Unit, Nuffield House, Queen Elizabeth Hospital, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Thorax 62:36-42. 2007
    ..Intravenous salbutamol (albuterol) reduces lung water in patients with the acute respiratory distress syndrome (ARDS). Experimental data show that it also reduces pulmonary neutrophil accumulation or activation and inflammation in ARDS...
  11. ncbi Quality of CPR during advanced resuscitation training
    Gavin D Perkins
    Clinical Trials Unit, Warwick Medical School, University of Warwick, CV4 7AL, United Kingdom
    Resuscitation 77:69-74. 2008
    ..This study investigated whether poor quality CPR during advanced life support training could be contributing to poor performance in clinical practice...
  12. ncbi Birmingham assessment of breathing study (BABS)
    Gavin D Perkins
    Division of Medical Sciences, University of Birmingham, Birmingham B152TT, UK
    Resuscitation 64:109-13. 2005
    ..The aim of this study was to test the ability of medical students to discriminate between simulated normal and abnormal breathing patterns and select the correct treatment...
  13. ncbi Variability in the assessment of advanced life support skills
    G D Perkins
    Department of Intensive Care Medicine, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK
    Resuscitation 50:281-6. 2001
    ..Validation of the assessment tools for the rapidly growing number of life support courses is required with urgent steps to improve reliability where required...
  14. ncbi Safety and tolerability of nonbronchoscopic lavage in ARDS
    Gavin D Perkins
    MB ChB, Clinical Research Block, University of Birmingham, Birmingham, UK, B15 2TT
    Chest 127:1358-63. 2005
    ..This study compared the safety profiles of bronchoscopic lavage with nonbronchoscopic lavage in the investigation of patients with acute lung injury (ALI) or ARDS...
  15. ncbi A comparison between over-the-head and standard cardiopulmonary resuscitation
    Gavin D Perkins
    Intensive Care Unit, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK
    Resuscitation 61:155-61. 2004
    ..The aim of this study was to investigate the technique of over-the-head CPR (OTH CPR), where the CPR provider kneels above the casualty and performs chest compressions OTH of the casualty...
  16. ncbi In vivo and in vitro effects of salbutamol on alveolar epithelial repair in acute lung injury
    G D Perkins
    Warwick Medical School, University of Warwick, Coventry, UK
    Thorax 63:215-20. 2008
    ..One possible explanation for the delay in change in extravascular lung water is the time required for salbutamol to stimulate alveolar epithelial repair...
  17. ncbi The effect of pre-course e-learning prior to advanced life support training: a randomised controlled trial
    Gavin D Perkins
    University of Warwick, Warwick Medical School, Warwick, United Kingdom
    Resuscitation 81:877-81. 2010
    ....
  18. ncbi What is the optimal duration of ventilation in the prone position in acute lung injury and acute respiratory distress syndrome?
    D F McAuley
    Intensive Care Unit, Birmingham Heartlands Teaching Hospital, Bordesley Green East, Birmingham B9 5SS, UK
    Intensive Care Med 28:414-8. 2002
    ....
  19. ncbi Regulation of vascular endothelial growth factor bioactivity in patients with acute lung injury
    G D Perkins
    Intensive Care Unit, Birmingham Heartlands Hospital, Birmingham, UK
    Thorax 60:153-8. 2005
    ..CONCLUSION: This study shows for the first time the presence of sVEGFR-1 in the BAL fluid of patients with ARDS. This may explain the presence of reduced bioactive VEGF in patients early in the course of ARDS...
  20. ncbi Does Dual Operator CPR help minimize interruptions in chest compressions?
    Jon F Fallaha
    The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Resuscitation 80:1011-4. 2009
    ..This study aims to determine if Dual Operator CPR reduces no-flow duration compared to Single Operator CPR...
  21. ncbi Neutrophil chemotaxis in granulomatosis with polyangiitis (Wegener's) and idiopathic pulmonary fibrosis
    A G Richter
    Lung Injury and Fibrosis Treatment Programme, Dept of Medical Sciences, University ofBirmingham, Birmingham, UK
    Eur Respir J 38:1081-8. 2011
    ..001). Our study confirms a neutrophilia and pro-inflammatory alveolar milieu that persists in clinical remission. CXCL8 and IL-1β appear to play important roles in the neutrophil chemotactic response to BALF...
  22. ncbi Role of nonbronchoscopic lavage for investigating alveolar inflammation and permeability in acute respiratory distress syndrome
    Gavin D Perkins
    Intensive Care Unit, Birmingham Heartlands Hospital, Birmingham, UK
    Crit Care Med 34:57-64. 2006
    ..CONCLUSIONS: Nonbronchoscopic lavage is not comparable to bronchoscopic lavage and as such cannot be used as an alternative to bronchoscopic lavage for assessing alveolar inflammation in patients with ARDS...
  23. ncbi The impact of manual defibrillation technique on no-flow time during simulated cardiopulmonary resuscitation
    Gavin D Perkins
    University of Birmingham, Birmingham B15 2TT, United Kingdom
    Resuscitation 73:109-14. 2007
    ....
  24. ncbi Recall after cardiac arrest scenario testing
    Robin P Davies
    Birmingham Heartlands Hospital, Birmingham B9 5SS, UK
    Resuscitation 68:239-42. 2006
    ..These findings provide some reassurance that the likelihood of successful collusion improving subsequent candidates performance is likely to be small as recall of the scenario progression is limited...
  25. ncbi Validation for a scoring system of the ALS cardiac arrest simulation test (CASTest)
    Fiona Napier
    Warwick Medical School, Gibbett Hill, Warwick CV4 7AL, United Kingdom
    Resuscitation 80:1034-8. 2009
    ..The aim of this study is to validate an alternative scoring system for measuring individual candidate performance during research involving the CASTest...
  26. ncbi Basic life support training for health care students
    G D Perkins
    Department of Medicine, Birmingham Heartlands Hospital, UK
    Resuscitation 41:19-23. 1999
    ..It forms part of an overall strategy for improving resuscitation training for undergraduates from all disciplines...
  27. ncbi The effect of differing support surfaces on the efficacy of chest compressions using a resuscitation manikin model
    M Tweed
    Respiratory Medicine, Leicester Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
    Resuscitation 51:179-83. 2001
    ..Air-filled support surfaces are deflated for cardiopulmonary resuscitation, with little evidence to substantiate this. We investigated the effect that differing support surfaces had on ECC efficacy using a CPR manikin model...
  28. ncbi Peer assessment of resuscitation skills
    Vittoria Bucknall
    The Medical School, University of Birmingham, UK
    Resuscitation 77:211-5. 2008
    ..The aim of this study was to test the expansion of the peer tuition model to include peer assessment of performance. The study also sought to establish the attitudes towards peer assessment among the course students and tutors...
  29. ncbi Compression feedback devices over estimate chest compression depth when performed on a bed
    Gavin D Perkins
    Warwick Medical School, University of Warwick, Warwick CV4 7AL, United Kingdom
    Resuscitation 80:79-82. 2009
    ..A secondary aim was to evaluate if placing a backboard beneath the victim would alter the degree of mattress compression...
  30. ncbi Use of advanced life support skills
    Jonathan Hulme
    Intensive Care Unit, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK
    Resuscitation 58:59-63. 2003
    ....
  31. ncbi The Acute Care Undergraduate TEaching (ACUTE) Initiative: consensus development of core competencies in acute care for undergraduates in the United Kingdom
    Gavin D Perkins
    Division of Medical Sciences, University of Birmingham, Birmingham, UK
    Intensive Care Med 31:1627-33. 2005
    ..The aim of this study was to use consensus techniques to identify the core competencies in the care of acutely ill or arrested adult patients that medical students should possess at the point of graduation...
  32. ncbi Do different mattresses affect the quality of cardiopulmonary resuscitation?
    Gavin D Perkins
    Department of Intensive Care Medicine, Birmingham Heartlands Hospital, B9 5SS, Birmingham, UK
    Intensive Care Med 29:2330-5. 2003
    ..To determine the effect of different mattresses on cardiopulmonary resuscitation performance and establish whether emergency deflation of an inflatable mattress improves the quality of resuscitation...
  33. ncbi Pulmonary manifestations of anti-neutrophil cytoplasmic antibody (ANCA)-positive vasculitis
    D R Thickett
    Lung Injury and Fibrosis Treatment Programme, Department of Medical Sciences, Division of Infection and Immunity, Medical School, University of Birmingham, Birmingham, UK
    Rheumatology (Oxford) 45:261-8. 2006
  34. ncbi Delays in defibrillation: influence of different monitoring techniques
    G D Perkins
    Department of Intensive Care Medicine, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK
    Br J Anaesth 89:405-8. 2002
    ..We recommend that initial monitoring through leads be discontinued in favour of hands-free adhesive pads or defibrillator paddles/gel pads...
  35. ncbi Bench-to-bedside review: beta2-Agonists and the acute respiratory distress syndrome
    Gavin D Perkins
    Consultant, Intensive Care Unit, Birmingham Heartlands Hospital, Birmingham, UK
    Crit Care 8:25-32. 2004
    ..The present review examines the evidence supporting a role for beta2-agonists as a specific pharmacological intervention in patients with ARDS...
  36. ncbi Mechanical chest-compression devices: current and future roles
    Gavin D Perkins
    University of Warwick, UK
    Curr Opin Crit Care 16:203-10. 2010
    ..Mechanical chest-compression devices provide an alternative to manual CPR. This review will consider the evidence and current indications for the use of these devices...
  37. ncbi Peer-led resuscitation training for healthcare students: a randomised controlled study
    Gavin D Perkins
    Department of Intensive Care Medicine, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK
    Intensive Care Med 28:698-700. 2002
    ..To determine the efficacy of a peer-led tuition model for training healthcare students in basic life support compared to tuition delivered by clinical tutors...
  38. ncbi An evaluation of objective feedback in basic life support (BLS) training
    Brendan B Spooner
    Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
    Resuscitation 73:417-24. 2007
    ..This study investigates the effects of continuous feedback from a manikin on chest compression and ventilation techniques during training compared to instructor feedback alone...
  39. ncbi Critically injured patients, inaccessible airways, and laryngeal mask airways
    J Hulme
    University Hospital Birmingham NHS Trust, Selly Oak Hospital, Birmingham, UK
    Emerg Med J 22:742-4. 2005
    ....
  40. ncbi Does the prophylactic administration of magnesium sulphate to patients undergoing thoracotomy prevent postoperative supraventricular arrhythmias? A randomized controlled trial
    T Saran
    Academic Department of Anaesthesia, Critical Care and Pain, Heart of England NHS Foundation Trust, Birmingham B9 5SS, UK
    Br J Anaesth 106:785-91. 2011
    ..This prospective, randomized, double-blind, placebo-controlled trial examined the effects of perioperative magnesium on the development of postoperative SVA...
  41. ncbi Advanced life support update
    Natalie Husselbee
    Warwick Medical School, University of Warwick, Coventry, UK
    Br Med Bull 89:79-91. 2009
    ..This review provides an update on the current treatment guidelines and identifies areas where these may be strengthened...
  42. ncbi The use of CPR feedback/prompt devices during training and CPR performance: A systematic review
    Joyce Yeung
    University of Warwick, UK
    Resuscitation 80:743-51. 2009
    ..In lay persons and health care providers performing cardiopulmonary resuscitation (CPR), does the use of CPR feedback/prompt devices when compared to no device improve CPR skill acquisition, retention, and real life performance?..
  43. ncbi Undergraduate training in the care of the acutely ill patient: a literature review
    Christopher M Smith
    Division of Medical Sciences, University of Birmingham, B15 2TT, Birmingham, UK
    Intensive Care Med 33:901-7. 2007
    ..To characterise the problem of teaching acute care skills to undergraduates and to look for potential solutions...
  44. ncbi Do changes in pulse oximeter oxygen saturation predict equivalent changes in arterial oxygen saturation?
    Gavin D Perkins
    Intensive Care Unit, Birmingham Heartlands and Solihull NHS Trust Teaching, Birmingham Heartlands Hospital, Birmingham, UK
    Crit Care 7:R67. 2003
    ....
  45. ncbi Discrepancies between clinical and postmortem diagnoses in critically ill patients: an observational study
    Gavin D Perkins
    Anaesthesia and Intensive Care Medicine, Intensive Care Unit, Birmingham Heartlands and Solihull NHS Trust (Teaching, Birmingham Heartlands Hospital, Birmingham, UK
    Crit Care 7:R129-32. 2003
    ..Recognition of the diagnoses missed before death may improve outcome or avoid unnecessary prolongation of life where terminal disease is present...
  46. ncbi Type XVIII collagen degradation products in acute lung injury
    Gavin D Perkins
    Lung Injury and Fibrosis Treatment Program LIFT, Department of Medical Sciences, The Medical School University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    Crit Care 13:R52. 2009
    ....
  47. ncbi Skill deployment and the ILS course
    Gavin D Perkins
    Resuscitation 64:245-6. 2005
  48. ncbi CPR and pressure care
    Mike Tweed
    J Wound Care 13:393. 2004
  49. ncbi In hospital cardiac arrest: missing links in the chain of survival
    Gavin D Perkins
    Resuscitation 66:253-5. 2005
  50. ncbi European Resuscitation Council guidelines for resuscitation 2005. Section 2. Adult basic life support and use of automated external defibrillators
    Anthony J Handley
    Resuscitation 67:S7-23. 2005
  51. ncbi The immediate life support course
    Jasmeet Soar
    Consultant in Anaesthesia and Intensive Care Medicine, North Bristol NHS Trust, BS10 5NB, Bristol, UK
    Resuscitation 57:21-6. 2003
    ..We also present the first year's results and discuss possible future developments. It is hoped that this course may become established in counties in continental Europe through the European Resuscitation Council...
  52. ncbi Chest-compression-only or full cardiopulmonary resuscitation?
    Gavin D Perkins
    Lancet 369:1926. 2007
  53. ncbi Study on respiratory rate
    Michael Tweed
    Respir Med 96:1045. 2002
  54. ncbi Over-the-head CPR
    Gavin D Perkins
    Anesth Analg 103:498; author reply 498-9. 2006
  55. ncbi Training in the management of the acutely ill medical patient
    Danny McAuley
    Birmingham Heartlands Teaching Hospital
    Clin Med 2:323-6. 2002
    ..This article identifies ways in which the recognised deficiencies in the care of the acutely ill medical patient can be improved...
  56. ncbi European Resuscitation Council guidelines for resuscitation 2005. Section 7. Cardiac arrest in special circumstances
    Jasmeet Soar
    Resuscitation 67:S135-70. 2005
  57. ncbi A role for heme oxygenase-1 in alveolar repair after wood smoke exposure?
    David R Thickett
    Crit Care Med 36:2697-8. 2008
  58. ncbi The assessment tool is only as good as the assessors
    Gavin D Perkins
    Med Educ 36:589-90. 2002
  59. ncbi Does MMP-12 play a role in human lung fibrosis?
    David R Thickett
    Am J Respir Cell Mol Biol 38:247; author reply 247. 2008