Nathalie Percie du Sert

Summary

Country: UK

Publications

  1. pmc Predicting the emetic liability of novel chemical entities: a comparative study
    Nathalie Percie du Sert
    The National Centre for the Replacement, Refinement and Reduction of Animals in Research, London, UK
    Br J Pharmacol 165:1848-67. 2012
  2. doi request reprint The delayed phase of cisplatin-induced emesis is mediated by the area postrema and not the abdominal visceral innervation in the ferret
    Nathalie Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, Cranmer Terrace, London, SW17 0RE, UK
    Neurosci Lett 465:16-20. 2009

Detail Information

Publications3

  1. pmc Predicting the emetic liability of novel chemical entities: a comparative study
    Nathalie Percie du Sert
    The National Centre for the Replacement, Refinement and Reduction of Animals in Research, London, UK
    Br J Pharmacol 165:1848-67. 2012
    ..The aim of the study is to compare the response induced by emetic compounds across species and investigate whether dogs, ferrets and rats are all similarly predictive of humans...
  2. doi request reprint The delayed phase of cisplatin-induced emesis is mediated by the area postrema and not the abdominal visceral innervation in the ferret
    Nathalie Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, Cranmer Terrace, London, SW17 0RE, UK
    Neurosci Lett 465:16-20. 2009
    ..6R+V (p=0.009) were observed in APX animals. These data suggest that, in contrast to the acute emetic response triggered by cisplatin, the delayed phase does not rely on abdominal visceral afferents but is mediated via the area postrema...