J Robert Sneyd

Summary

Affiliation: Peninsula Medical School
Country: UK

Publications

  1. doi request reprint First human administration of MR04A3: a novel water-soluble nonbenzodiazepine sedative
    J Robert Sneyd
    Peninsula Medical School, University of Plymouth, Plymouth, United Kingdom
    Anesthesiology 116:385-95. 2012
  2. doi request reprint Inhalational or total intravenous anaesthesia: is total intravenous anaesthesia useful and are there economic benefits?
    J Robert Sneyd
    Peninsula Medical School, University of Plymouth, UK
    Curr Opin Anaesthesiol 24:182-7. 2011
  3. pmc First administration to man of Org 25435, an intravenous anaesthetic: A Phase 1 Clinical Trial
    Ann E Rigby-Jones
    Peninsula College of Medicine and Dentistry, University of Plymouth, The John Bull Building, Research Way, Tamar Science Park, Plymouth PL6 8BU, UK
    BMC Anesthesiol 10:10. 2010
  4. ncbi request reprint Multicentre evaluation of the adenosine agonist GR79236X in patients with dental pain after third molar extraction
    J R Sneyd
    Anaesthesia Research Group, Peninsula Medical School, The John Bull Building, Tamar Science Park, Drake Circus, Plymouth PL6 8BU, and Department of Anaesthesia, Northwick Park Hospital, Harrow, UK
    Br J Anaesth 98:672-6. 2007
  5. ncbi request reprint Comparison of propofol/remifentanil and sevoflurane/remifentanil for maintenance of anaesthesia for elective intracranial surgery
    J R Sneyd
    Peninsula Medical School, C310 Portland Square, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK
    Br J Anaesth 94:778-83. 2005
  6. ncbi request reprint Recent advances in intravenous anaesthesia
    J R Sneyd
    Peninsula Medical School, Portland Square, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK
    Br J Anaesth 93:725-36. 2004
  7. ncbi request reprint Drugs in anaesthesia
    Robert Sneyd
    Plymouth Hospitals NHS Trust, Derriford, UK
    Anaesthesia 58:1183-6. 2003
  8. ncbi request reprint A single exposure to hyperbaric oxygen does not cause oxidative stress in isolated platelets: no effect on superoxide dismutase, catalase, or cellular ATP
    Frances L Shaw
    Institute of Biomedical and Clinical Science, Peninsula Medical School, Exeter, EX1 2LU, UK
    Clin Biochem 38:722-6. 2005
  9. ncbi request reprint Remifentanil and fentanyl during anaesthesia for major abdominal and gynaecological surgery. An open, comparative study of safety and efficacy
    J R Sneyd
    Department of Anaesthesia, Derriford Hospital, Plymouth, PL6 8DH, Devon, UK
    Eur J Anaesthesiol 18:605-14. 2001
  10. doi request reprint Propofol and children--what we know and what we do not know
    Ann E Rigby-Jones
    Anaesthesia Research Group, Peninsula Medical School, Peninsula College of Medicine and Dentistry, University of Plymouth, Plymouth, UK
    Paediatr Anaesth 21:247-54. 2011

Collaborators

Detail Information

Publications14

  1. doi request reprint First human administration of MR04A3: a novel water-soluble nonbenzodiazepine sedative
    J Robert Sneyd
    Peninsula Medical School, University of Plymouth, Plymouth, United Kingdom
    Anesthesiology 116:385-95. 2012
    ..49, is a novel isoindoline water-soluble benzodiazepine receptor agonist with favorable anesthetic/sedative properties in animals. MR04A3 is a 1% aqueous presentation of JM-1232(-)...
  2. doi request reprint Inhalational or total intravenous anaesthesia: is total intravenous anaesthesia useful and are there economic benefits?
    J Robert Sneyd
    Peninsula Medical School, University of Plymouth, UK
    Curr Opin Anaesthesiol 24:182-7. 2011
    ..In practice, studies using easier to measure proxy endpoints dominate - even though the limitations of such research are well known...
  3. pmc First administration to man of Org 25435, an intravenous anaesthetic: A Phase 1 Clinical Trial
    Ann E Rigby-Jones
    Peninsula College of Medicine and Dentistry, University of Plymouth, The John Bull Building, Research Way, Tamar Science Park, Plymouth PL6 8BU, UK
    BMC Anesthesiol 10:10. 2010
    ..This study aimed to assess the safety, tolerability and efficacy of Org 25435 and to obtain preliminary pharmacodynamic and pharmacokinetic data...
  4. ncbi request reprint Multicentre evaluation of the adenosine agonist GR79236X in patients with dental pain after third molar extraction
    J R Sneyd
    Anaesthesia Research Group, Peninsula Medical School, The John Bull Building, Tamar Science Park, Drake Circus, Plymouth PL6 8BU, and Department of Anaesthesia, Northwick Park Hospital, Harrow, UK
    Br J Anaesth 98:672-6. 2007
    ..Adenosine is analgesic in humans, and the selective adenosine A1 receptor agonist GR79236X has significant anti-nociceptive activity in an animal pain model of inflammatory pain...
  5. ncbi request reprint Comparison of propofol/remifentanil and sevoflurane/remifentanil for maintenance of anaesthesia for elective intracranial surgery
    J R Sneyd
    Peninsula Medical School, C310 Portland Square, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK
    Br J Anaesth 94:778-83. 2005
    ..Propofol and sevoflurane are suitable agents for maintenance of anaesthesia during neurosurgical procedures. We have prospectively compared these agents in combination with the short-acting opioid, remifentanil...
  6. ncbi request reprint Recent advances in intravenous anaesthesia
    J R Sneyd
    Peninsula Medical School, Portland Square, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK
    Br J Anaesth 93:725-36. 2004
    ..It may be useful in subhypnotic doses for postsurgical patients with pain refractory to morphine administration...
  7. ncbi request reprint Drugs in anaesthesia
    Robert Sneyd
    Plymouth Hospitals NHS Trust, Derriford, UK
    Anaesthesia 58:1183-6. 2003
  8. ncbi request reprint A single exposure to hyperbaric oxygen does not cause oxidative stress in isolated platelets: no effect on superoxide dismutase, catalase, or cellular ATP
    Frances L Shaw
    Institute of Biomedical and Clinical Science, Peninsula Medical School, Exeter, EX1 2LU, UK
    Clin Biochem 38:722-6. 2005
    ..The aim of the study was to investigate whether a single hyperbaric oxygen exposure causes oxidative stress in isolated platelets...
  9. ncbi request reprint Remifentanil and fentanyl during anaesthesia for major abdominal and gynaecological surgery. An open, comparative study of safety and efficacy
    J R Sneyd
    Department of Anaesthesia, Derriford Hospital, Plymouth, PL6 8DH, Devon, UK
    Eur J Anaesthesiol 18:605-14. 2001
    ..8% isoflurane (end-tidal concentration) for major abdominal and gynaecological surgery, and the efficacy and safety of remifentanil for pain management in the immediate postoperative period...
  10. doi request reprint Propofol and children--what we know and what we do not know
    Ann E Rigby-Jones
    Anaesthesia Research Group, Peninsula Medical School, Peninsula College of Medicine and Dentistry, University of Plymouth, Plymouth, UK
    Paediatr Anaesth 21:247-54. 2011
    ..K(eo) half-lives have been determined for pediatric kinetic models using time to peak effect techniques but are not currently incorporated into commercially available target-controlled infusion pumps...
  11. ncbi request reprint Pharmacokinetics of propofol infusions in critically ill neonates, infants, and children in an intensive care unit
    Ann E Rigby-Jones
    Department of Pharmacy, Derriford Hospital, Plymouth Postgraduate Medical School, Plymouth, UK
    Anesthesiology 97:1393-400. 2002
    ..Few data have described propofol kinetics in critically ill children...
  12. doi request reprint New drugs and technologies, intravenous anaesthesia is on the move (again)
    J R Sneyd
    Anaesthesia Research Group, Peninsula Medical School, University of Plymouth, The John Bull Building, Research Way, Tamar Science Park, Plymouth PL6 8BU, UK
    Br J Anaesth 105:246-54. 2010
    ..Computer-controlled drug administration offers the ability to automatically implement infusion schemes too complex for manual use and the possibility of linking patient monitoring to administration to enhance patient safety...
  13. ncbi request reprint Oxidative metabolism in platelets, platelet aggregation, and hematology in patients undergoing multiple hyperbaric oxygen exposures
    R D Handy
    School of Biological Sciences, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK
    Undersea Hyperb Med 32:327-40. 2005
    ..Overall, we found no evidence that 20 HBO2 sessions caused adverse effects on platelet aggregation or oxidative metabolism in platelets, red or white cell counts, or total antioxidant status of the plasma...
  14. ncbi request reprint Remifentanil-midazolam sedation for paediatric patients receiving mechanical ventilation after cardiac surgery
    A E Rigby-Jones
    Anaesthesia Research Group, Peninsula Medical School, Plymouth, UK
    Br J Anaesth 99:252-61. 2007
    ..This study aimed to determine the pharmacokinetics of remifentanil in children requiring ventilation after cardiac surgery...