Alison N Jeffery

Summary

Affiliation: Peninsula Medical School
Country: UK

Publications

  1. pmc Age before stage: insulin resistance rises before the onset of puberty: a 9-year longitudinal study (EarlyBird 26)
    Alison N Jeffery
    University Medicine, Peninsula Medical School, Plymouth, UK
    Diabetes Care 35:536-41. 2012
  2. ncbi request reprint Little evidence for early programming of weight and insulin resistance for contemporary children: EarlyBird Diabetes Study report 19
    Alison N Jeffery
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth, United Kingdom
    Pediatrics 118:1118-23. 2006
  3. pmc Ethical dilemmas: feeding back results to members of a longitudinal cohort study
    A Jeffery
    EarlyBird Study, Children s Day Beds, Level 12, Derriford Hospital, Plymouth PL6 8DH, UK
    J Med Ethics 31:153. 2005
  4. pmc Parents' awareness of overweight in themselves and their children: cross sectional study within a cohort (EarlyBird 21)
    A N Jeffery
    Peninsula Medical School, University Medicine, Derriford Hospital, Plymouth PL6 8DH
    BMJ 330:23-4. 2005
  5. doi request reprint Adiponectin in childhood
    Alison N Jeffery
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, UK
    Int J Pediatr Obes 3:130-40. 2008
  6. ncbi request reprint Behavior of insulin resistance and its metabolic correlates in prepubertal children: a longitudinal study (EarlyBird 32)
    Alison N Jeffery
    Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, Plymouth, UK
    Diabetes Care 30:2962-4. 2007
  7. ncbi request reprint Preventable factors in childhood that lead to insulin resistance, diabetes mellitus and the metabolic syndrome: the EarlyBird diabetes study 1
    Linda D Voss
    The EarlyBird Research Centre, Peninsula Medical School, Plymouth, UK
    J Pediatr Endocrinol Metab 16:1211-24. 2003
  8. doi request reprint Changes in resting energy expenditure and their relationship to insulin resistance and weight gain: a longitudinal study in pre-pubertal children (EarlyBird 17)
    Joanne Hosking
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, Plymouth, UK
    Clin Nutr 29:448-52. 2010
  9. doi request reprint Trends, associations and predictions of insulin resistance in prepubertal children (EarlyBird 29)
    Daphne S L Gardner
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, Plymouth, UK
    Pediatr Diabetes 9:214-20. 2008
  10. ncbi request reprint The impact of pregnancy weight and glucose on the metabolic health of mother and child in the south west of the UK
    Alison N Jeffery
    Peninsula Medical School, Plymouth Campus, UK
    Midwifery 20:281-9. 2004

Collaborators

Detail Information

Publications24

  1. pmc Age before stage: insulin resistance rises before the onset of puberty: a 9-year longitudinal study (EarlyBird 26)
    Alison N Jeffery
    University Medicine, Peninsula Medical School, Plymouth, UK
    Diabetes Care 35:536-41. 2012
    ..We sought to establish from longitudinal data its relationship to pubertal onset, and interactions with age, sex, adiposity, and IGF-1...
  2. ncbi request reprint Little evidence for early programming of weight and insulin resistance for contemporary children: EarlyBird Diabetes Study report 19
    Alison N Jeffery
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth, United Kingdom
    Pediatrics 118:1118-23. 2006
    ..The aim of this study was to evaluate whether adaptive responses made to the uterine or very early infant environment are affecting the current metabolic health of young children in the United Kingdom...
  3. pmc Ethical dilemmas: feeding back results to members of a longitudinal cohort study
    A Jeffery
    EarlyBird Study, Children s Day Beds, Level 12, Derriford Hospital, Plymouth PL6 8DH, UK
    J Med Ethics 31:153. 2005
  4. pmc Parents' awareness of overweight in themselves and their children: cross sectional study within a cohort (EarlyBird 21)
    A N Jeffery
    Peninsula Medical School, University Medicine, Derriford Hospital, Plymouth PL6 8DH
    BMJ 330:23-4. 2005
  5. doi request reprint Adiponectin in childhood
    Alison N Jeffery
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, UK
    Int J Pediatr Obes 3:130-40. 2008
    ..However, adiponectin's role as a predictor of metabolic dysfunction in healthy, normal-weight youngsters is less clear...
  6. ncbi request reprint Behavior of insulin resistance and its metabolic correlates in prepubertal children: a longitudinal study (EarlyBird 32)
    Alison N Jeffery
    Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, Plymouth, UK
    Diabetes Care 30:2962-4. 2007
  7. ncbi request reprint Preventable factors in childhood that lead to insulin resistance, diabetes mellitus and the metabolic syndrome: the EarlyBird diabetes study 1
    Linda D Voss
    The EarlyBird Research Centre, Peninsula Medical School, Plymouth, UK
    J Pediatr Endocrinol Metab 16:1211-24. 2003
    ..It situates the anthropometric, physical activity and dietary status of the EarlyBird children and provides a detailed metabolic profile of the British 5 year-old in the year 2000...
  8. doi request reprint Changes in resting energy expenditure and their relationship to insulin resistance and weight gain: a longitudinal study in pre-pubertal children (EarlyBird 17)
    Joanne Hosking
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, Plymouth, UK
    Clin Nutr 29:448-52. 2010
    ..Little is known of these associations in children. Our aim was to test the hypothesis that long-term weight gain in children is met with adaptive changes in resting energy expenditure, mediated by insulin resistance and/or leptin...
  9. doi request reprint Trends, associations and predictions of insulin resistance in prepubertal children (EarlyBird 29)
    Daphne S L Gardner
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, Plymouth, UK
    Pediatr Diabetes 9:214-20. 2008
    ..Rising obesity has been observed in all age groups. Anthropometric cut-points have been used to predict metabolic risk in children, although they are not based on known outcomes...
  10. ncbi request reprint The impact of pregnancy weight and glucose on the metabolic health of mother and child in the south west of the UK
    Alison N Jeffery
    Peninsula Medical School, Plymouth Campus, UK
    Midwifery 20:281-9. 2004
    ..to explore relationships between maternal pre-pregnancy weight, third trimester glucose, baby birth weight, weight and metabolic health of the mother and child 5 years after birth...
  11. doi request reprint Resting energy expenditure, adiponectin and changes in body composition of young children (EarlyBird 34)
    Joanne Hosking
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, UK
    Int J Pediatr Obes 3:46-51. 2008
    ..REE is not a significant predictor of future weight gain or adverse change in body composition and, although the period of follow-up was limited, adiponectin seems unlikely to confound such a relationship in healthy young children...
  12. doi request reprint The relationship of height and body fat to gender-assortative weight gain in children. A longitudinal cohort study (EarlyBird 44)
    Olubukola Ajala
    Department of Endocrinology and Metabolism, Peninsula College of Medicine and Dentistry Plymouth Campus, UK
    Int J Pediatr Obes 6:223-8. 2011
    ..Height, body fat and body mass index (BMI) are correlated in children, so we hypothesized that the gender-assortative associations in BMI recently reported in contemporary children might extend to their height and body fat...
  13. doi request reprint Little impact of resting energy expenditure on childhood weight and body composition: a longitudinal study (EarlyBird 47)
    Joanne Hosking
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, UK
    Nutr Res 31:9-13. 2011
    ..Resting energy expenditure does not appear to provide an explanation for childhood obesity...
  14. pmc Objectively measured physical activity and its association with adiponectin and other novel metabolic markers: a longitudinal study in children (EarlyBird 38)
    Brad S Metcalf
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, Plymouth, UK
    Diabetes Care 32:468-73. 2009
    ..Recent evidence suggests that, in children, traditional markers of metabolic disturbance are related only weakly to physical activity. We therefore sought to establish the corresponding relationships with newer metabolic markers...
  15. doi request reprint Direction of causality between body fat and insulin resistance in children--a longitudinal study (EarlyBird 51)
    Joanne Hosking
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, UK
    Int J Pediatr Obes 6:428-33. 2011
    ..To investigate the direction of causality in the association between adiposity and insulin resistance in children...
  16. doi request reprint Contribution of early weight gain to childhood overweight and metabolic health: a longitudinal study (EarlyBird 36)
    Daphne S L Gardner
    Department of Endocrinology and Metabolism, Peninsula College of Medicine and Dentistry, Plymouth Campus, Plymouth, UK
    Pediatrics 123:e67-73. 2009
    ..There is a scarcity of longitudinal studies in contemporary children reporting the impact of early weight gain on metabolic health...
  17. ncbi request reprint The relative contributions of birth weight, weight change, and current weight to insulin resistance in contemporary 5-year-olds: the EarlyBird Study
    Terence J Wilkin
    Department of Medicine, The Peninsula Medical School, Plymouth Campus, U K Department Clinical Chemistry, Derriford Hospital, Plymouth PL6 8DH, U K
    Diabetes 51:3468-72. 2002
    ..89 and 0.88 units, respectively, P = 0.96; girls 1.26 and 1.13 units, P = 0.41). Insulin resistance in contemporary children seems to be a function of excess current weight rather than of low birth weight or change in weight...
  18. ncbi request reprint Validation of foot-to-foot bioelectrical impedance analysis with dual-energy X-ray absorptiometry in the assessment of body composition in young children: the EarlyBird cohort
    Joanne Hosking
    Department of Endocrinology and Metabolism, Peninsula Medical School, Plymouth Campus, Plymouth, UK
    Br J Nutr 96:1163-8. 2006
    ..Therefore, BIA may be useful for large-scale studies but is not interchangeable with DEXA and should be interpreted with caution in individuals...
  19. ncbi request reprint Sex differences in resting energy expenditure and their relation to insulin resistance in children (EarlyBird 13)
    Jo Kirkby
    Peninsula Medical School, Plymouth, United Kingdom
    Am J Clin Nutr 80:430-5. 2004
    ..Resting energy expenditure (REE) is variable among individuals and is one of many factors controlling body mass...
  20. doi request reprint Consistency of children's dietary choices: annual repeat measures from 5 to 13 years (EarlyBird 49)
    Alissa E Frémeaux
    Department of Endocrinology and Metabolism, Peninsula College of Medicine and Dentistry, University Medicine, Level 7, Derriford Hospital, Plymouth PL6 8DH, UK
    Br J Nutr 106:725-31. 2011
    ..The quality of diet diminished over time in 29 % of the children and improved in only 14 %. Dietary habits appear to be set early and seldom improve spontaneously...
  21. pmc A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses
    Michael N Weedon
    Institute of Biomedical and Clinical Science, Peninsula Medical School, Exeter, EX1 2LU, UK
    Am J Hum Genet 79:991-1001. 2006
    ..In conclusion, a comprehensive analysis of common variation of the glucokinase gene shows that this is the first gene to be reproducibly associated with fasting glucose and fetal growth...
  22. doi request reprint Distribution of adiponectin, leptin, and metabolic correlates of insulin resistance: a longitudinal study in British children; 1: Prepuberty (EarlyBird 15)
    Michael J Murphy
    Division of Pathology and Neuroscience, University of Dundee, Dundee, UK
    Clin Chem 54:1298-306. 2008
    ..We sought to establish age- and sex-specific distributions of metabolic correlates of insulin resistance in healthy prepubertal children...
  23. ncbi request reprint Does lean rather than fat mass provide the link between birth weight, BMI, and metabolic risk? EarlyBird 23
    Michael J Murphy
    Division of Pathology and Neuroscience, University of Dundee, Dundee, UK
    Pediatr Diabetes 7:211-4. 2006
    ..This apparent paradox might be explained if high birth weight programmed a greater proportion of subsequent lean mass, which carries less cardiovascular risk than fat tissue...
  24. ncbi request reprint Girls at five are intrinsically more insulin resistant than boys: The Programming Hypotheses Revisited--The EarlyBird Study (EarlyBird 6)
    Michael J Murphy
    Department of Molecular and Cellular Pathology, University of Dundee, Dundee, United Kingdom
    Pediatrics 113:82-6. 2004
    ..Girls are more insulin resistant than boys. We aimed in the present report to establish how much of the sex difference in insulin resistance is intrinsic...