Anwar Padhani

Summary

Affiliation: Paul Strickland Scanner Centre
Country: UK

Publications

  1. ncbi Reproducibility of dynamic contrast-enhanced MRI in human muscle and tumours: comparison of quantitative and semi-quantitative analysis
    Susan M Galbraith
    Gray Cancer Institute, Mount Vernon Hospital, Middlesex HA6 2JR, UK
    NMR Biomed 15:132-42. 2002
  2. pmc Imaging oxygenation of human tumours
    Anwar R Padhani
    Paul Strickland Scanner Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex, HA6 2RN, UK
    Eur Radiol 17:861-72. 2007
  3. ncbi Angiogenesis imaging in the management of prostate cancer
    Anwar R Padhani
    Paul Strickland Scanner Centre based at Mount Vernon Hospital, Middlesex, UK
    Nat Clin Pract Urol 2:596-607. 2005
  4. ncbi Prediction of clinicopathologic response of breast cancer to primary chemotherapy at contrast-enhanced MR imaging: initial clinical results
    Anwar R Padhani
    Cancer Research UK Clinical Magnetic Resonance Research Group and the Breast Unit, Institute of Cancer Research and the Royal Marsden NHS Trust, Surrey, England
    Radiology 239:361-74. 2006
  5. ncbi Antivascular cancer treatments: functional assessments by dynamic contrast-enhanced magnetic resonance imaging
    A R Padhani
    Paul Strickland Scanner Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex HA6 2RN, United Kingdom
    Abdom Imaging 30:324-41. 2005
  6. pmc PET imaging of tumour hypoxia
    Anwar Padhani
    Paul Strickland Scanner Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex, HA6 2RN, UK
    Cancer Imaging 6:S117-21. 2006
  7. doi Science to practice: what does MR oxygenation imaging tell us about human breast cancer hypoxia?
    Anwar Padhani
    Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Rickmansworth Road, Northwood, Middlesex HA6 2RN UK
    Radiology 254:1-3. 2010
  8. doi Clinical utility of diffusion-weighted magnetic resonance imaging in prostate cancer
    Asim Afaq
    Department of Diagnostic Imaging, Royal Marsden Hospital, London, UK
    BJU Int 108:1716-22. 2011
  9. ncbi 18fluorodeoxyglucose positron emission tomography in the prediction of relapse in patients with high-risk, clinical stage I nonseminomatous germ cell tumors: preliminary report of MRC Trial TE22--the NCRI Testis Tumour Clinical Study Group
    Robert A Huddart
    Academic Radiotherapy, Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, UK
    J Clin Oncol 25:3090-5. 2007
  10. ncbi Bayesian methods for pharmacokinetic models in dynamic contrast-enhanced magnetic resonance imaging
    Volker J Schmid
    Institute of Biomedical Engineering, Imperial College, London SW7 2AZ, UK
    IEEE Trans Med Imaging 25:1627-36. 2006

Collaborators

Detail Information

Publications39

  1. ncbi Reproducibility of dynamic contrast-enhanced MRI in human muscle and tumours: comparison of quantitative and semi-quantitative analysis
    Susan M Galbraith
    Gray Cancer Institute, Mount Vernon Hospital, Middlesex HA6 2JR, UK
    NMR Biomed 15:132-42. 2002
    ..Pixel analyses slightly improve reproducibility estimates and retain information about spatial heterogeneity. Reproducibility studies are recommended when treatment effects are being monitored...
  2. pmc Imaging oxygenation of human tumours
    Anwar R Padhani
    Paul Strickland Scanner Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex, HA6 2RN, UK
    Eur Radiol 17:861-72. 2007
    ..We discuss where developments are required for hypoxia imaging to become clinically useful and explore potential new uses for hypoxia imaging techniques including biological conformal radiotherapy...
  3. ncbi Angiogenesis imaging in the management of prostate cancer
    Anwar R Padhani
    Paul Strickland Scanner Centre based at Mount Vernon Hospital, Middlesex, UK
    Nat Clin Pract Urol 2:596-607. 2005
    ..Ultimately, local availability, expertise and the need to minimize patients' radiation burden will influence which technique is used in prostatic evaluations...
  4. ncbi Prediction of clinicopathologic response of breast cancer to primary chemotherapy at contrast-enhanced MR imaging: initial clinical results
    Anwar R Padhani
    Cancer Research UK Clinical Magnetic Resonance Research Group and the Breast Unit, Institute of Cancer Research and the Royal Marsden NHS Trust, Surrey, England
    Radiology 239:361-74. 2006
    ....
  5. ncbi Antivascular cancer treatments: functional assessments by dynamic contrast-enhanced magnetic resonance imaging
    A R Padhani
    Paul Strickland Scanner Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex HA6 2RN, United Kingdom
    Abdom Imaging 30:324-41. 2005
    ..Such developments will be essential for multicenter trials in which it will be necessary to establish effective cross-site standardization of measurements and evaluation...
  6. pmc PET imaging of tumour hypoxia
    Anwar Padhani
    Paul Strickland Scanner Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex, HA6 2RN, UK
    Cancer Imaging 6:S117-21. 2006
    ....
  7. doi Science to practice: what does MR oxygenation imaging tell us about human breast cancer hypoxia?
    Anwar Padhani
    Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Rickmansworth Road, Northwood, Middlesex HA6 2RN UK
    Radiology 254:1-3. 2010
    ..The ability of air breathing R2* measurements to reflect tissue hypoxia appears to be tumor type-specific, which should prompt further exploration of this image contrast mechanism in both human and animal tumors...
  8. doi Clinical utility of diffusion-weighted magnetic resonance imaging in prostate cancer
    Asim Afaq
    Department of Diagnostic Imaging, Royal Marsden Hospital, London, UK
    BJU Int 108:1716-22. 2011
    ..This mini-review concisely summarises, for clinical managing patients with prostate cancer, the clinical utility of diffusion weighted MRI...
  9. ncbi 18fluorodeoxyglucose positron emission tomography in the prediction of relapse in patients with high-risk, clinical stage I nonseminomatous germ cell tumors: preliminary report of MRC Trial TE22--the NCRI Testis Tumour Clinical Study Group
    Robert A Huddart
    Academic Radiotherapy, Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, UK
    J Clin Oncol 25:3090-5. 2007
    ....
  10. ncbi Bayesian methods for pharmacokinetic models in dynamic contrast-enhanced magnetic resonance imaging
    Volker J Schmid
    Institute of Biomedical Engineering, Imperial College, London SW7 2AZ, UK
    IEEE Trans Med Imaging 25:1627-36. 2006
    ....
  11. ncbi Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening study
    Ruth M L Warren
    Department of Radiology, Addenbrooke s Hospital, Cambridge, England, and Department of Radiology, University of Aberdeen, Aberdeen, Scotland
    Radiology 239:677-85. 2006
    ..To evaluate prospectively the accuracy of a lesion classification system designed for use in a magnetic resonance (MR) imaging high-breast-cancer-risk screening study...
  12. ncbi Statistical analysis of pharmacokinetic models in dynamic contrast-enhanced magnetic resonance imaging
    Volker J Schmid
    Institute for Biomedical Engineering, Suite 5, Sherfield Building, Imperial College, South Kensington, London SW7 2AZ, United Kingdom
    Med Image Comput Comput Assist Interv 8:886-93. 2005
    ..Further analysis has also shown that Bayesian methods are more accurate and do not suffer from convergence problems, but at a higher computational cost...
  13. ncbi Functional imaging of colorectal cancer angiogenesis
    Vicky Goh
    Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
    Lancet Oncol 8:245-55. 2007
    ..Their comparability with other imaging techniques, in particular ultrasound, and their limitations are also addressed...
  14. ncbi Dynamic contrast enhanced MRI in prostate cancer
    Roberto Alonzi
    Marie Curie Research Wing, Mount Vernon Cancer Centre, Rickmansworth Road, Northwood, Middlesex, HA6 2RN, United Kingdom
    Eur J Radiol 63:335-50. 2007
    ..Limitations include inadequate lesion characterisation particularly differentiating prostatitis from cancer, and in distinguishing between BPH and central gland tumours...
  15. pmc Imaging tumour angiogenesis
    Tony Jeswani
    Department of Radiology, Royal Free Hospital, London, NW3 2QG, UK
    Cancer Imaging 5:131-8. 2005
    ....
  16. pmc Where are we with imaging oxygenation in human tumours?
    Anwar R Padhani
    Cancer Imaging 5:128-30. 2005
    ....
  17. ncbi Assessing changes in tumour vascular function using dynamic contrast-enhanced magnetic resonance imaging
    Carmel Hayes
    CRC Clinical Magnetic Resonance Research Group, The Institute of Cancer Research and The Royal Marsden NHS Trust, Downs Road, Sutton SM2 5PT, UK
    NMR Biomed 15:154-63. 2002
    ..Thus, for higher pre-treatment K(trans) values, a greater decrease was observed. Greater changes were observed in the upper extremes of the K(trans) histogram than in the median values after one course of treatment...
  18. ncbi Effects of 5,6-dimethylxanthenone-4-acetic acid on human tumor microcirculation assessed by dynamic contrast-enhanced magnetic resonance imaging
    Susan M Galbraith
    Department of Medical Oncology and Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, United Kingdom
    J Clin Oncol 20:3826-40. 2002
    ..Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) studies were performed in the phase I trials to examine changes related to blood flow and permeability in tumor and muscle...
  19. ncbi Perfusion MR imaging of extracranial tumor angiogenesis
    Anwar R Padhani
    Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
    Top Magn Reson Imaging 15:41-57. 2004
    ..For dynamic MRI to enter into widespread clinical practice, it will be necessary to develop standardized approaches to measurement and robust analysis approaches...
  20. ncbi Dynamic magnetic resonance imaging of tumor perfusion. Approaches and biomedical challenges
    David J Collins
    Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom
    IEEE Eng Med Biol Mag 23:65-83. 2004
  21. ncbi MRI in the detection and management of breast cancer
    Anwar R Padhani
    Mount Vernon Hospital, Paul Strickland Scanner Centre, Rickmansworth Road, Northwood, Middlesex HA6 2RN, UK
    Expert Rev Anticancer Ther 5:239-52. 2005
    ..This article will review both the technical aspects of performing and interpreting breast MRI, as well as the current and possible future roles of breast MRI, comparing its strengths and weaknesses with conventional imaging...
  22. ncbi Imaging breast cancer response during neoadjuvant systemic therapy
    Mark Beresford
    Mount Vernon Cancer Centre, Northwood, Middlesex, HA6 2RN, UK
    Expert Rev Anticancer Ther 5:893-905. 2005
    ..These techniques measure changes in tumor vasculature, metabolism or proliferation and may prove to be earlier and more sensitive measures of response to systemic therapy, thus enabling tailoring of an individual's treatment...
  23. ncbi Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging
    Susan M Galbraith
    Department of Medical Oncology, Mount Vernon Hospital, Northwood, Middlesex, United Kingdom
    J Clin Oncol 21:2831-42. 2003
    ..Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) studies were performed to examine changes in parameters related to blood flow and vascular permeability in tumor and normal tissue after CA4P treatment. Materials and..
  24. ncbi Dynamic MRI for imaging tumor microvasculature: comparison of susceptibility and relaxivity techniques in pelvic tumors
    Katharine J Lankester
    Department of Medical Oncology, Mount Vernon Hospital, Northwood, Middlesex, UK
    J Magn Reson Imaging 25:796-805. 2007
    ....
  25. ncbi Magnetic resonance imaging of induration in the irradiated breast
    Anwar R Padhani
    UKCR Clinical Magnetic Resonance Research Group, Institute of Cancer Research and the Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, UK
    Radiother Oncol 64:157-62. 2002
    ..The purpose of this study is to describe morphological magnetic resonance imaging (MRI) appearances and MRI-derived microvascular functional characteristics of the indurated breast several years post-treatment...
  26. doi Coupled modeling of blood perfusion in intravascular, interstitial spaces in tumor microvasculature
    Jie Wu
    Department of Mechanics and Engineering Science, Fudan University, Handan Road 220, Shanghai 200433, China
    J Biomech 41:996-1004. 2008
    ....
  27. doi Technology insight: water diffusion MRI--a potential new biomarker of response to cancer therapy
    Daniel M Patterson
    Department of Medical Oncology, Mount Vernon Hospital, Northwood, UK
    Nat Clin Pract Oncol 5:220-33. 2008
    ..The strength of evidence for adoption of DW-MRI as a biomarker for the assessment of tumor response is presented...
  28. ncbi Reproducibility of quantitative dynamic MRI of normal human tissues
    Anwar R Padhani
    CRC Clinical Magnetic Resonance Research Group, Institute of Cancer Research and the Royal Marsden NHS Trust, Downs Road, Sutton, Surrey SM2 5PT, UK
    NMR Biomed 15:143-53. 2002
    ..Reproducibility studies of normal and pathological tissues should be incorporated into clinical research protocols that measure treatment effects by DCE-MRI techniques...
  29. ncbi Tumor antivascular effects of radiotherapy combined with combretastatin a4 phosphate in human non-small-cell lung cancer
    Quan Sing Ng
    Marie Curie Research Wing, Mount Vernon Hospital, Middlesex, United Kingdom
    Int J Radiat Oncol Biol Phys 67:1375-80. 2007
    ....
  30. ncbi Acute tumor vascular effects following fractionated radiotherapy in human lung cancer: In vivo whole tumor assessment using volumetric perfusion computed tomography
    Quan Sing Ng
    Marie Curie Research Wing, Mount Vernon Hospital, Northwood, United Kingdom
    Int J Radiat Oncol Biol Phys 67:417-24. 2007
    ..To quantitatively assess the in vivo acute vascular effects of fractionated radiotherapy for human non-small-cell lung cancer using volumetric perfusion computed tomography (CT)...
  31. ncbi Dynamic contrast-enhanced MRI in clinical oncology: current status and future directions
    Anwar R Padhani
    Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK
    J Magn Reson Imaging 16:407-22. 2002
    ..Ongoing challenges faced by DCE-MRI as clinical and research tools will be explored...
  32. ncbi Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy
    James L Tatum
    National Cancer Institute, Executive Plaza North, Room 6000, 6130 Executive Boulevard, Rockville, MD 20852 7440, USA
    Int J Radiat Biol 82:699-757. 2006
    ....
  33. ncbi Dynamic MRI of breast hardness following radiation treatment
    Anwar R Padhani
    CRUK Clinical Magnetic Resonance Research Group, Institute of Cancer Research and the Royal Marsden Hospital, Downs Road, Sutton, UK
    J Magn Reson Imaging 17:427-34. 2003
    ..To evaluate functional microvascular characteristics of breast induration several years after radiation treatment using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) techniques...
  34. ncbi Inter- and intraobserver variability in the evaluation of dynamic breast cancer MRI
    Mark J Beresford
    Mount Vernon Cancer Centre, Northwood, United Kingdom
    J Magn Reson Imaging 24:1316-25. 2006
    ..To quantify variations within and between observers ascribable to manual region of interest (ROI) placement in patients with breast cancer undergoing dynamic MRI...
  35. ncbi Quantitative assessment of lung cancer perfusion using MDCT: does measurement reproducibility improve with greater tumor volume coverage?
    Quan Sing Ng
    Marie Curie Research Wing, Mount Vernon Hospital, Northwood, Middlesex, United Kingdom
    AJR Am J Roentgenol 187:1079-84. 2006
    ..We aimed to determine if greater z-axis tumor coverage improves the reproducibility of perfusion CT measurements in lung cancer...
  36. ncbi A test of performance of breast MRI interpretation in a multicentre screening study
    Ruth Warren
    Department of Radiology, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Magn Reson Imaging 24:917-29. 2006
    ..The aim of this study was to assess the consistency and performance of radiologists interpreting breast magnetic resonance imaging (MRI) examinations...
  37. ncbi Lung cancer perfusion at multi-detector row CT: reproducibility of whole tumor quantitative measurements
    Quan Sing Ng
    Marie Curie Research Wing and Paul Strickland Scanner Centre, Mount Vernon Hospital, Rickmansworth Rd, Northwood, Middlesex, England
    Radiology 239:547-53. 2006
    ..Coefficient of variation of 9.49% for permeability and 26.31% for blood volume and inter- and intraobserver variability ranging between 3.30% and 6.34% indicate reliable assessment with this whole tumor technique...
  38. ncbi Dynamic contrast-enhanced magnetic resonance imaging of radiation therapy-induced microcirculation changes in rectal cancer
    Quido G de Lussanet
    Department of Radiology, Maastricht University Hospital, Maastricht, The Netherlands
    Int J Radiat Oncol Biol Phys 63:1309-15. 2005
    ..This study evaluated radiation therapy related microvascular changes in locally advanced rectal cancer by DCE-MRI and histology...
  39. ncbi Informatics in Radiology (infoRAD): Magnetic Resonance Imaging Workbench: analysis and visualization of dynamic contrast-enhanced MR imaging data
    James A d'Arcy
    Cancer Research UK Clinical MR Research Group, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey, United Kingdom SM2 5PT
    Radiographics 26:621-32. 2006
    ..MRIW is written in IDL, enabling it to be used on a variety of computer systems...