Stephen Westaby

Summary

Affiliation: Oxford Heart Centre
Country: UK

Publications

  1. doi request reprint Rotary blood pumps as definitive treatment for severe heart failure
    Stephen Westaby
    Oxford University Hospitals Trust, John Radcliffe Hospital, Department of Cardiac Surgery, Oxford, OX3 9DU, UK
    Future Cardiol 9:199-213. 2013
  2. doi request reprint Cardiogenic shock in ACS. Part 1: prediction, presentation and medical therapy
    Stephen Westaby
    Departments of Cardiothoracic Surgery, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Nat Rev Cardiol 9:158-71. 2012
  3. doi request reprint Cardiogenic shock in ACS. Part 2: Role of mechanical circulatory support
    Stephen Westaby
    Department of Cardiothoracic Surgery, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Nat Rev Cardiol 9:195-208. 2012
  4. pmc Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion
    Kyriakos Anastasiadis
    Department of Cardiothoracic Surgery, AHEPA Hospital, Thessaloniki, Greece
    J Transl Med 9:12. 2011
  5. doi request reprint Repair of type B interrupted aortic arch using aberrant right subclavian artery
    Stephen Westaby
    Department of Congenital Cardiac Surgery, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Interact Cardiovasc Thorac Surg 9:528-9. 2009
  6. ncbi request reprint Aortic root remodeling in atheromatous aneurysms: the role of selected sinus repair
    Stephen Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, The John Radcliffe Hospital, Headleyway, Headington, Oxford OX3 9DU, UK
    Eur J Cardiothorac Surg 21:459-64. 2002
  7. ncbi request reprint Acute type A dissection: conservative methods provide consistently low mortality
    Stephen Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Headington, England
    Ann Thorac Surg 73:707-13. 2002
  8. ncbi request reprint Postauricular percutaneous power delivery for permanent mechanical circulatory support
    Stephen Westaby
    Oxford Heart Centre, Oxford, United Kingdom
    J Thorac Cardiovasc Surg 123:977-83. 2002
  9. ncbi request reprint Circulatory support for long-term treatment of heart failure: experience with an intraventricular continuous flow pump
    Stephen Westaby
    Oxford Heart Centre, Oxford, UK
    Circulation 105:2588-91. 2002
  10. ncbi request reprint The Jarvik 2000 Heart. Clinical validation of the intraventricular position
    Stephen Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, The John Radcliffe Hospital, Headleyway, Headington, Oxford OX3 9DU, UK
    Eur J Cardiothorac Surg 22:228-32. 2002

Detail Information

Publications96

  1. doi request reprint Rotary blood pumps as definitive treatment for severe heart failure
    Stephen Westaby
    Oxford University Hospitals Trust, John Radcliffe Hospital, Department of Cardiac Surgery, Oxford, OX3 9DU, UK
    Future Cardiol 9:199-213. 2013
    ..Comprehensive healthcare systems must consider contemporary evidence and provide the most symptomatic of heart failure patients with effective care. Cardiac resynchronization therapy is no longer the ceiling for this...
  2. doi request reprint Cardiogenic shock in ACS. Part 1: prediction, presentation and medical therapy
    Stephen Westaby
    Departments of Cardiothoracic Surgery, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Nat Rev Cardiol 9:158-71. 2012
    ..When mean arterial pressure is <55 mmHg with serum lactate >11 mmol/l, death is likely and mechanical circulatory support becomes the only chance for survival...
  3. doi request reprint Cardiogenic shock in ACS. Part 2: Role of mechanical circulatory support
    Stephen Westaby
    Department of Cardiothoracic Surgery, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Nat Rev Cardiol 9:195-208. 2012
    ..Published series demonstrate that 50-75% of patients with profound shock can be salvaged either through native heart recovery, urgent transplantation, or switch to a long-term pump...
  4. pmc Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion
    Kyriakos Anastasiadis
    Department of Cardiothoracic Surgery, AHEPA Hospital, Thessaloniki, Greece
    J Transl Med 9:12. 2011
    ..The aforementioned hypothesis has to be tested with well-designed prospective multicentre studies...
  5. doi request reprint Repair of type B interrupted aortic arch using aberrant right subclavian artery
    Stephen Westaby
    Department of Congenital Cardiac Surgery, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Interact Cardiovasc Thorac Surg 9:528-9. 2009
    ..In order to gain the full length of this vessel it was mobilised from a left thoracotomy. The aberrant vessel provides autogenous patch material with which to enlarge the ascending aorta and left common carotid artery...
  6. ncbi request reprint Aortic root remodeling in atheromatous aneurysms: the role of selected sinus repair
    Stephen Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, The John Radcliffe Hospital, Headleyway, Headington, Oxford OX3 9DU, UK
    Eur J Cardiothorac Surg 21:459-64. 2002
    ..We studied the outcome after selective sinus replacement in 29 consecutive AAA patients between 1995 and 2001...
  7. ncbi request reprint Acute type A dissection: conservative methods provide consistently low mortality
    Stephen Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Headington, England
    Ann Thorac Surg 73:707-13. 2002
    ..In this high-risk setting, we believe that a conservative approach to the aortic root and the complete resection of the primary tear are important. We reviewed the results of this policy from our aortic surgery database...
  8. ncbi request reprint Postauricular percutaneous power delivery for permanent mechanical circulatory support
    Stephen Westaby
    Oxford Heart Centre, Oxford, United Kingdom
    J Thorac Cardiovasc Surg 123:977-83. 2002
    ..We have now used this method in patients implanted with the Jarvik 2000 heart (Jarvik Heart, Inc, New York, NY) as destination therapy for end-stage (New York Heart Association class IV) heart failure...
  9. ncbi request reprint Circulatory support for long-term treatment of heart failure: experience with an intraventricular continuous flow pump
    Stephen Westaby
    Oxford Heart Centre, Oxford, UK
    Circulation 105:2588-91. 2002
    ..After extensive laboratory testing, we began clinical trials with an axial flow pump for long-term treatment of New York Heart Association class IV, transplant-ineligible patients...
  10. ncbi request reprint The Jarvik 2000 Heart. Clinical validation of the intraventricular position
    Stephen Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, The John Radcliffe Hospital, Headleyway, Headington, Oxford OX3 9DU, UK
    Eur J Cardiothorac Surg 22:228-32. 2002
    ..After extensive laboratory experience we sought to evaluate the intraventricular Jarvik 2000 Heart in patients with endstage heart failure...
  11. pmc Comparison of hospital episode statistics and central cardiac audit database in public reporting of congenital heart surgery mortality
    Stephen Westaby
    Department of Cardiac Surgery, Oxford Radcliffe Hospital NHS Trust, Oxford OX3 9DU
    BMJ 335:759. 2007
    ..To verify or refute the value of hospital episode statistics (HES) in determining 30 day mortality after open congenital cardiac surgery in infants nationally in comparison with central cardiac audit database (CCAD) information...
  12. ncbi request reprint Coronary revascularization in ischemic cardiomyopathy
    Stephen Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Surg Clin North Am 84:179-99, x. 2004
    ..The outcome following revascularization in the heart failure patient, the results of revascularization, and the time course of functional recovery after coronary artery bypass graft are also covered...
  13. ncbi request reprint The longest functioning heart valve prosthesis?
    Stephen Westaby
    Department of Cardiac Surgery, John Radcliffe Hospital, Oxford, United Kingdom
    J Thorac Cardiovasc Surg 134:1049-50. 2007
  14. ncbi request reprint Advanced heart failure--an "off-the-shelf" solution?
    Stephen Westaby
    Oxford Heart Centre, Oxford OX3 9DU, UK
    Lancet 371:1898-900. 2008
  15. pmc Houston and oxford: a celebration of international fellowship
    Stephen Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Tex Heart Inst J 32:303-17. 2005
  16. doi request reprint Destination therapy with a rotary blood pump and novel power delivery
    Stephen Westaby
    Department of Cardiothoracic Surgery, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Eur J Cardiothorac Surg 37:350-6. 2010
    ..We tested the hypothesis that a miniaturised axial flow pump with infection-resistant power delivery could improve longevity and quality of life (QOL) in advanced heart failure patients deemed unsuitable for transplantation...
  17. ncbi request reprint Surgical options in heart failure
    Stephen Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Headington, United Kingdom
    Surg Clin North Am 84:xv-xix. 2004
  18. ncbi request reprint Ventricular assist devices as destination therapy
    Stephen Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Surg Clin North Am 84:91-123. 2004
    ..Further clinical trials of destination therapy are indicated and must use more reliable blood pumps implanted before terminal decline into multiorgan failure...
  19. ncbi request reprint Lifetime circulatory support must not be restricted to transplant centers
    Stephen Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Oxford, UK
    Heart Fail Clin 3:369-75. 2007
    ..User-friendly blood pumps with proven durability already exist. Rotary blood pumps must be made available in centers other than those involved in transplantation. The mystique must be removed from this relatively simple intervention...
  20. ncbi request reprint First permanent implant of the Jarvik 2000 Heart
    S Westaby
    Oxford Heart Centre, John Radcliffe Hospital, UK
    Lancet 356:900-3. 2000
    ..The availability of donor hearts is severely limited, therefore an alternative approach is necessary. We have explored the use of a new type of left-ventricular assist device intended as a long-term solution to end-stage heart failure...
  21. ncbi request reprint Infant partial left ventriculectomy for failure to wean from cardiopulmonary bypass
    S Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, United Kingdom
    Ann Thorac Surg 71:717-9. 2001
    ..We performed partial left ventriculectomy (Batista procedure) that halved left atrial pressure and enabled discontinuation of bypass. Postoperative recovery was then uneventful...
  22. ncbi request reprint Survival advantage of stentless aortic bioprostheses
    S Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, Headington, United Kingdom
    Ann Thorac Surg 70:785-90; discussion 790-1. 2000
    ..Stentless BPs offer established hemodynamic benefits. We sought to determine whether these advantages translate into improved survival...
  23. ncbi request reprint Mechanical bridge to recovery in fulminant myocarditis
    S Westaby
    Department of Cardiac Surgery, John Radcliffe Hospital Oxford, England
    Ann Thorac Surg 70:278-82; discussion 282-3. 2000
    ..Widespread application of this method depends on the availability of an inexpensive user friendly blood pump, appropriate weaning protocols and emerging strategies to promote sustainable myocardial recovery...
  24. ncbi request reprint Aortic root replacement with coronary button re-implantation: low risk and predictable outcome
    S Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Headley Way, Headington, Oxford, UK
    Eur J Cardiothorac Surg 17:259-65. 2000
    ..We analyzed a 10 year experience of all root replacement operations by one surgeon to determine the incidence of coronary complications and risk factors for early mortality...
  25. ncbi request reprint Direct repair of giant right coronary aneurysm
    S Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, The John Radcliffe Hospital, England
    Ann Thorac Surg 68:1401-3. 1999
    ..Instead of aneurysm ligation and coronary bypass we mobilized the inflow and outflow and performed end-to-end anastomosis. This preserved the native vessel. Restudy in both patients confirmed the effectiveness of this technique...
  26. ncbi request reprint Implant technique for the Jarvik 2000 Heart
    Stephen Westaby
    Oxford Heart Centre and The Heart Hospital, London, United Kingdom
    Ann Thorac Surg 73:1337-40. 2002
    ..A vascular graft offloads to the descending thoracic aorta so that only the left pleural cavity is opened. Power supply is through an abdominal drive line or postauricular titanium pedestal according to the treatment strategy...
  27. ncbi request reprint Maximizing survival potential in very high risk cardiac surgery
    Stephen Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Oxford, UK
    Heart Fail Clin 3:159-80. 2007
    ..In the absence of the transplant option, more innovative circulatory support strategies are required to improve survival in the postcardiotomy setting...
  28. ncbi request reprint Reoperation after type A dissection repair
    S Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Headington, United Kingdom
    J Card Surg 17:26-34. 2002
  29. ncbi request reprint Is there a relationship between cognitive dysfunction and systemic inflammatory response after cardiopulmonary bypass?
    S Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Oxford, England
    Ann Thorac Surg 71:667-72. 2001
    ..The aim of the present study was to evaluate the relationship between the SIR and postoperative cognitive performance at 5 days and 3 months...
  30. ncbi request reprint Systemic levels of endothelin correlate with systemic inflammation and not with myocardial injury or left ventricular ejection fraction in patients undergoing percutaneous coronary intervention and on-pump coronary artery bypass grafting
    Florim Cuculi
    Oxford Heart Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Interact Cardiovasc Thorac Surg 13:585-9. 2011
    ..44, P = 0.0002). ET-1 rise is more pronounced in on-pump CABG and ET-1 production could be driven by periprocedural inflammatory reaction...
  31. doi request reprint Effects of left ventricular volume overload on mitochondrial and death-receptor-mediated apoptotic pathways in the transition to heart failure
    Narain Moorjani
    Department of Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford, United Kingdom
    Am J Cardiol 103:1261-8. 2009
    ..Mitochondrial (Bax, p53, caspase 9) and death-receptor mediated (TNFR1, caspase 8) pathways are upregulated but without completion of DNA fragmentation...
  32. ncbi request reprint Transventricular pulmonary valve implantation in corrected truncus arteriosus
    Suvitesh Luthra
    Department of Cardiothoracic Surgery, John Radcliffe Hospital, Oxford, United Kingdom
    Ann Thorac Surg 93:660-1. 2012
    ..We describe a safe, alternative hybrid transapical approach from the right ventricle that avoids the extensive dissection and potential complications of revision surgery...
  33. ncbi request reprint Elective transfer from cardiopulmonary bypass to centrifugal blood pump support in very high-risk cardiac surgery
    Stephen Westaby
    John Radcliffe Hospital, Oxford, UK
    J Thorac Cardiovasc Surg 133:577-8. 2007
  34. ncbi request reprint Upregulation of Bcl-2 proteins during the transition to pressure overload-induced heart failure
    Narain Moorjani
    Department of Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford OX3 9DY, United Kingdom
    Int J Cardiol 116:27-33. 2007
    ..In this study, activity of the Bcl-2 family of mitochondrial apoptotic proteins and their regulator (p53) were assessed during the transition to heart failure...
  35. ncbi request reprint Early diagnosis of perioperative myocardial infarction after coronary bypass grafting: a study using biomarkers and cardiac magnetic resonance imaging
    Chris C S Lim
    Oxford Heart Centre, John Radcliffe Hospital, Oxford, United Kingdom
    Ann Thorac Surg 92:2046-53. 2011
    ..This study characterized early changes in biomarkers after revascularization injury during on-pump CABG...
  36. ncbi request reprint Mechanical bridge to recovery in pheochromocytoma myocarditis
    Stephen Westaby
    Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK stephen westaby orh nhs uk
    Nat Rev Cardiol 6:482-7. 2009
    ..Apart from a family history of coronary artery disease there was no other medical history of note...
  37. ncbi request reprint Circulatory support with attenuated pulse pressure alters human aortic wall morphology
    Stephen Westaby
    Oxford Heart Center, John Radcliffe Hospital, Department of Cardiothoracic Surgery, Oxford, Oxfordshire, United Kingdom
    J Thorac Cardiovasc Surg 133:575-6. 2007
  38. ncbi request reprint Activation of apoptotic caspase cascade during the transition to pressure overload-induced heart failure
    Narain Moorjani
    Department of Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford, England
    J Am Coll Cardiol 48:1451-8. 2006
    ..A pressure overload model was developed to simulate aortic stenosis and assess caspase activity during the transition to heart failure...
  39. ncbi request reprint Stentless bioprostheses in aortic root disease
    S Westaby
    Oxford Heart Centre, The John Radcliffe Hospital, Headington, Oxford, UK
    Semin Thorac Cardiovasc Surg 13:273-82. 2001
    ..CONCLUSIONS: Stentless bioprostheses are no longer confined to AVR alone. Experience supports the use of stentless bioprostheses where aortic homografts were previously applied. With availability in a wide range of sizes...
  40. pmc Myocardial perfusion and oxygenation are impaired during stress in severe aortic stenosis and correlate with impaired energetics and subclinical left ventricular dysfunction
    Masliza Mahmod
    Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford Centre for Clinical Magnetic Resonance Research OCMR, Oxford OX3 9DU, UK
    J Cardiovasc Magn Reson 16:29. 2014
    ..We aimed to assess myocardial oxygenation in severe AS without obstructive coronary artery disease, and to investigate its association with myocardial energetics and function...
  41. ncbi request reprint Myocardial steatosis and left ventricular contractile dysfunction in patients with severe aortic stenosis
    Masliza Mahmod
    Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford Centre for Clinical Magnetic Resonance Research, Oxford, United Kingdom
    Circ Cardiovasc Imaging 6:808-16. 2013
    ..Aortic stenosis (AS) leads to left ventricular (LV) hypertrophy and dysfunction. We hypothesized that cardiac steatosis is involved in the pathophysiology and also assessed whether it is reversible after aortic valve replacement...
  42. ncbi request reprint Ventricular septal rupture following abciximab infusion
    Jayanth R Arnold
    Department of Cardiology, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Eur J Echocardiogr 9:60-2. 2008
    ..We report a case of rupture of the ventricular septum occurring after treatment with the glycoprotein IIb-IIIa receptor blocker abciximab, in the absence of thrombolysis...
  43. ncbi request reprint Spontaneous echocardiographic contrast in the ascending aorta mimicking the appearance of aortic dissection in a patient with a left ventricular assist device
    Dermot G Nicolson
    Department of Cardiology, John Radcliffe Hospital, Oxford, UK
    Echocardiography 21:193-5. 2004
    ..As patients with LVAD are increasing in number, clinicians should be aware of this possible effect...
  44. doi request reprint Chronic atrial fibrillation is associated with reduced survival after aortic and double valve replacement
    Richard Schulenberg
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford, United Kingdom
    Ann Thorac Surg 89:738-44. 2010
    ..This study investigated long-term outcome in valve prosthesis patients with or without AF...
  45. ncbi request reprint Myocardial perfusion imaging after coronary artery bypass surgery using cardiovascular magnetic resonance: a validation study
    J Ranjit Arnold
    University of Oxford Centre for Clinical Magnetic Resonance Research, John Radcliffe Hospital, Oxford, United Kingdom
    Circ Cardiovasc Imaging 4:312-8. 2011
    ..The objective of this study was to test whether absolute quantification of perfusion with cardiovascular magnetic resonance systematically underestimates MBF in segments subtended by bypass grafts...
  46. ncbi request reprint Does the use of a stentless bioprosthesis increase surgical risk?
    S Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Headington, Oxford, UK
    Semin Thorac Cardiovasc Surg 13:143-7. 2001
    ..During the learning curve selective use of SBPs increased hospital mortality for AVR +/- CABG. Consecutive use dispelled the difference and the literature now suggests that SBPs may reduce hospital mortality for high-risk patients...
  47. ncbi request reprint Surgery for heart failure: now something for everyone?
    Stephen Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Headington, Oxford, UK
    Heart Fail Clin 3:139-57. 2007
    ..The recent remarkable developments in blood pump bioengineering provide an alternative approach and a platform on which to base genetic or stem cell therapies...
  48. ncbi request reprint Isolated ventricular noncompaction with left ventricular thrombus
    Jonathan Timperley
    The Oxford Heart Centre, The John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom
    Echocardiography 22:51-2. 2005
  49. ncbi request reprint A pressure overload model to track the molecular biology of heart failure
    Narain Moorjani
    Department of Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford OX3 9DY, UK
    Eur J Cardiothorac Surg 24:920-5. 2003
    ..To investigate this, we developed an ovine model of pressure overload-induced heart failure, in which serial left ventricular biopsies were obtained...
  50. ncbi request reprint Pericardial and porcine stentless aortic valves: are they hemodynamically different?
    X Y Jin
    Department of Cardiac Surgery, Oxford Heart Centre, Oxford Radcliffe Hospitals, United Kingdom
    Ann Thorac Surg 71:S311-4. 2001
    ..We sought to compare the early hemodynamic performance of pericardial stentless aortic valves with that of well-established porcine stentless aortic prostheses...
  51. doi request reprint Destination therapy: time for real progress
    Stephen Westaby
    Oxford Radcliffe NHS Trust, Oxford, UK
    Nat Clin Pract Cardiovasc Med 5:477-83. 2008
    ..Anecdotal evidence from 7.5 years of event-free survival in the first patient to receive a 'destination' axial flow pump permits justifiable optimism about the future of this approach. It is now time for real progress...
  52. ncbi request reprint Fifty years of thoracic aortic surgery: lessons learned and future directions
    Stephen Westaby
    Department of Cardiac Surgery, John Radcliffe Hospital, Oxford, United Kingdom
    Ann Thorac Surg 83:S832-4; discussion S846-50. 2007
    ..These are less intimidating for the patient but have unsolved risks with uncertain long-term outcome. In the future, an evidence-based balance between conventional surgical procedures versus interventional strategies is required...
  53. ncbi request reprint In vivo hemodynamic characteristics of porcine stentless aortic valves
    X Y Jin
    Department of Cardiac Surgery, Oxford Heart Centre, Oxford Radcliffe Hospitals, Oxford, UK
    Semin Thorac Cardiovasc Surg 13:67-74. 2001
    ..Ultimately, the variations in aortic root anatomy, surgical experience and their interactions are likely to become major determinants of in vivo performance of stentless aortic valves...
  54. ncbi request reprint Proximal aortic perfusion with passive cerebral flow: a method to prevent cerebral embolism in the arch and descending aortic operation
    T Katsumata
    Department of Cardiac Surgery, Oxford Heart Centre, The John Radcliffe Hospital, Headington, England
    J Card Surg 14:194-6. 1999
    ..It minimizes the risk of embolization into the brachiocephalic arteries of debris and malperfusion of the dissected aorta...
  55. ncbi request reprint Mycotic false aneurysm of the ascending aorta
    Satoshi Saito
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford, United Kingdom
    Ann Thorac Surg 75:1331. 2003
  56. doi request reprint With the "universal definition," measurement of creatine kinase-myocardial band rather than troponin allows more accurate diagnosis of periprocedural necrosis and infarction after coronary intervention
    Chris C S Lim
    Oxford Heart Centre, John Radcliffe Hospital, United Kingdom
    J Am Coll Cardiol 57:653-61. 2011
    ..We aimed to assess the differential implications of creatine kinase-myocardial band (CK-MB) and troponin measurement with the universal definition of periprocedural injury after percutaneous coronary intervention...
  57. doi request reprint Rupture of a left sinus of valsalva aneurysm with coronary compression: a rare cause of ischemic chest pain
    Florim Cuculi
    Department of Cardiology, Oxford Radcliffe Hospitals, Oxford, United Kingdom
    Ann Thorac Surg 92:e97-9. 2011
    ..This case report demonstrates the difficulty dealing with the minority of patients presenting with presumed ST elevation myocardial infarction, but for whom the life-saving treatment is surgery...
  58. ncbi request reprint Endovascular stent placement is an acceptable alternative to reoperation in selected infants with residual or recurrent aortic arch obstruction
    Jamie Bentham
    Department of Paediatric Cardiology and Cardiothoracic Surgery, John Radcliffe Hospital, Oxford, United Kingdom
    Catheter Cardiovasc Interv 76:852-9. 2010
    ..To describe endovascular stent placement in infants as a technically feasible option in circumstances where surgery is considered less favorable...
  59. doi request reprint Cardiac development after salvage partial left ventriculectomy in an infant with anomalous left coronary artery from the pulmonary artery
    Stephen Westaby
    Department of Cardiothoracic Surgery, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Thorac Cardiovasc Surg 136:784-5. 2008
  60. ncbi request reprint Operation of mid-arch coarctation
    T Katsumata
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, England
    Ann Thorac Surg 67:1386-90. 1999
    ..Coarctation occurring within the aortic arch is rare and may present difficulties during surgical repair. We describe the operative technique and outcome in 6 patients with this unusual anomaly...
  61. ncbi request reprint Replacement of the thoracic aorta with collagen-impregnated woven Dacron grafts. Early results
    S Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Headington, England
    J Thorac Cardiovasc Surg 106:427-33. 1993
    ..Needle holes self-seal rapidly. Medium-term follow-up by clinical, angiographic, computed tomographic, and magnetic resonance imaging techniques showed no late graft complications--specifically, no dilatation or thrombus formation...
  62. ncbi request reprint Pericardial stentless aortic valves: effects of sizing on hemodynamics and root geometry
    X Y Jin
    Department of Cardiac Surgery, Oxford Heart Centre, Oxford Radcliffe Hospitals, Oxford, UK
    Semin Thorac Cardiovasc Surg 13:55-9. 2001
    ..Pericardial stentless valves may be of advantage in elderly patients with significant geometric root mismatch...
  63. ncbi request reprint Anomalous left coronary artery from the pulmonary artery: a simple method for aortic implantation with autogenous arterial tissue
    T Katsumata
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, England
    Ann Thorac Surg 68:1090-1. 1999
    ..Both autogenous aortic and pulmonary arterial flaps create an extended left main stem without the disadvantages of standard rerouting techniques and full potential for growth remains...
  64. ncbi request reprint Stentless xenograft repair of excavating aortic root sepsis
    T Katsumata
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, Headington, United Kingdom
    J Card Surg 13:440-4. 1998
    ..As an alternative we used a stentless porcine xenograft root (Medtronic Freestyle valve) to manage this problem...
  65. ncbi request reprint Surgical restoration of the failing left ventricle
    Stephen Westaby
    Department of Cardiac Surgery, Oxford Heart Centre, The John Radcliffe Hospital, Oxford Radcliffe NHS Trust, Headington, Oxford, United Kingdom
    Med Clin North Am 87:523-52, xiii. 2003
    ..Consequently, there is a need to evaluate new surgical options for the deteriorating HF patient...
  66. doi request reprint Induction by left ventricular overload and left ventricular failure of the human Jumonji gene (JARID2) encoding a protein that regulates transcription and reexpression of a protective fetal program
    Esta Bovill
    Department of Medicine, University College London, London, UK
    J Thorac Cardiovasc Surg 136:709-16. 2008
    ....
  67. ncbi request reprint Allograft carotid artery as a systemic-to-pulmonary conduit
    Betsy Jane Evans
    John Radcliffe Hospital, Cardiac Surgery, Oxford, UK
    J Thorac Cardiovasc Surg 133:1367-8. 2007
  68. doi request reprint Diabetic and nondiabetic patients with left main and/or 3-vessel coronary artery disease: comparison of outcomes with cardiac surgery and paclitaxel-eluting stents
    Adrian P Banning
    Cardiology Department, John Radcliffe Hospital, Oxford, UK
    J Am Coll Cardiol 55:1067-75. 2010
    ....
  69. ncbi request reprint Neurological and cognitive disorders after coronary artery bypass grafting
    D P Taggart
    Oxford Heart Centre, John Radcliffe Hospital, Oxford OX3 9DU, England
    Curr Opin Cardiol 16:271-6. 2001
    ..The use of composite arterial grafts performed on the beating heart may be the most effective way of minimizing the risk of cerebral injury associated with CABG...
  70. ncbi request reprint Postcardiac surgery mediastinitis mimicking acute inferior myocardial infarction
    P A Catarino
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, England
    J Card Surg 15:309-12. 2000
    ..We describe a case of poststernotomy mediastinitis which produced electrocardiographic changes mimicking an acute inferior myocardial infarction...
  71. doi request reprint Cannulation techniques for temporary right and left ventricular support: simple solutions for a difficult problem
    Ravi J De Silva
    The Oxford Heart Centre, The John Radcliffe Hospital, Headington, Oxford, UK
    Eur J Cardiothorac Surg 42:728-30. 2012
    ..The modern cardiac surgeon needs to have a safe strategy for dealing with these complex cases. We report two cases that illustrate simple and safe cannulation techniques for temporary left and right ventricular failure...
  72. ncbi request reprint Diagnosis and management of aortoesophageal fistula caused by a foreign body
    Giuseppe S Sica
    Department of Surgery, Oxford, United Kingdom
    Ann Thorac Surg 77:2217-8. 2004
    ..A case of aortoesophageal fistula caused by a swallowed fish bone leading to respiratory arrest is reported. The clinical presentation was unusual. The successful treatment required the use of hypothermic circulatory arrest...
  73. ncbi request reprint Reliable long-term non-pulsatile circulatory support without anticoagulation
    S Saito
    Oxford Heart Centre, John Radcliffe Hospital, Headley Way, Headington, OX3 9DU, Oxford, UK
    Eur J Cardiothorac Surg 19:678-83. 2001
    ..Mechanical reliability and biocompatibility were demonstrated. Organ function remained within normal limits during continuous non-pulsatile flow...
  74. ncbi request reprint Iliac vein replacement with a descending aortic homograft
    A Handa
    Department of Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, United Kingdom
    Ann Thorac Surg 72:957-8. 2001
    ..We describe successful replacement of the iliac vein using a descending aortic homograft. The ilio femoral system was avulsed after recannulation of the femoral vein during a third cardiac reoperation...
  75. ncbi request reprint Dental bar tracheopexy in a neonate
    P A Catarino
    Department of Cardiac Surgery, Oxford Heart Centre, John Radcliffe Hospital, United Kingdom
    Ann Thorac Surg 72:943-4. 2001
    ..We report here the use of a dental bar as an external splint for tracheopexy in a neonate. Follow-up to 18 months shows good tracheal growth and no erosion...
  76. ncbi request reprint Heart failure surgery: a speciality in itself
    S Westaby
    Oxford Heart Centre, John Radcliffe Hospital, Department of Cardiothoracic Surgery, Oxford, UK
    Scand J Surg 96:140-53. 2007
  77. ncbi request reprint Pioneers of cardiology: Stephen Westaby, BSc, MS, PhD, FRCS, FESC. Interview by Mark Nicholls
    Stephen Westaby
    Circulation 115:f115-7. 2007
  78. ncbi request reprint Current diagnostic strategies in heart failure
    Manel Ballester-Rodes
    Service of Cardiology, Hospital Universitari Arnau de Vilanova, Department of Medicine, Faculty of Medicine, University of Lleida Catalunya, Spain
    J Nucl Cardiol 9:31S-39S. 2002
  79. ncbi request reprint Initial clinical experience with the Jarvik 2000 implantable axial-flow left ventricular assist system
    O H Frazier
    Cullen Cardiovascular Surgical Research Laboratories, Texas Heart Institute, Houston, USA
    Circulation 105:2855-60. 2002
    ..Seven patients underwent transplantation and 3 died during support. No device thrombosis was observed at explantation...
  80. pmc Use of the Jarvik 2000 left ventricular assist system as a bridge to heart transplantation or as destination therapy for patients with chronic heart failure
    O H Frazier
    Texas Heart Institute at St Luke s Episcopal Hospital, PO Box 20345, Houston, TX 77225 0345, USA
    Ann Surg 237:631-6; discussion 636-7. 2003
    ..To evaluate the Jarvik 2000 axial flow left ventricular assist system (LVAS) as a bridge to transplant and as destination therapy...
  81. ncbi request reprint Clinical experience with an implantable, intracardiac, continuous flow circulatory support device: physiologic implications and their relationship to patient selection
    O H Frazier
    Texas Heart Institute at St Luke s Episcopal Hospital, Houston, Texas 77225 0345, USA
    Ann Thorac Surg 77:133-42. 2004
    ..Subsequently, a decade of animal experiments with a larger, longer-term continuous-flow pump (the Jarvik 2000) confirmed the safety and efficacy of intraventricular placement, leading to its clinical application...
  82. ncbi request reprint Surgical management of valvular heart disease 2004
    W R Eric Jamieson
    St Paul s Hospital, Vancouver, British Columbia
    Can J Cardiol 20:7E-120E. 2004
  83. pmc Surgical mortality: Media attack
    Stephen Westaby
    BMJ 335:839; author reply 839-40. 2007
  84. doi request reprint The Peter Houghton legacy
    Stephen Westaby
    Artif Organs 32:363-5. 2008
  85. ncbi request reprint Anterior approach to implant the Jarvik 2000 with retroauricular power supply
    Michael P Siegenthaler
    Department of Cardiovascular Surgery, University of Freiburg, Freiburg, Germany
    Ann Thorac Surg 80:745-7. 2005
    ..If the outflow graft to the ascending aorta indeed reduces aortic stasis and thromboembolic events, the anterior approach with retroauricular power delivery might evolve into a standard procedure...
  86. ncbi request reprint Advanced heart failure: feasibility study of long-term continuous axial flow pump support
    Michael P Siegenthaler
    Center for Cardiovascular Disease, University of Freiburg Medical Center, Hugstetterstrasse 55, 79106 Freiburg, Germany
    Eur Heart J 26:1031-8. 2005
    ..We tested the hypothesis that a new continuous flow circulatory assist device could be employed safely to relieve symptoms of heart failure and evaluated the potential to prolong life...
  87. ncbi request reprint Hemodynamics of chronic nonpulsatile flow: implications for LVAD development
    Satoshi Saito
    Tokyo Women s Medical University, Japan
    Surg Clin North Am 84:61-74. 2004
    ..Their reliability and user-friendly status may soon allow implantation at an earlier stage of cardiac deterioration. Doubts about the feasibility of long-term pulseless circulation are disappearing...
  88. ncbi request reprint Six years of continuous mechanical circulatory support
    Stephen Westaby
    N Engl J Med 355:325-7. 2006
  89. ncbi request reprint Pulmonary-artery dissection in patients with Eisenmenger's syndrome
    Stephen Westaby
    N Engl J Med 356:2110-2. 2007
  90. pmc Mechanical circulatory support in the UK
    Stephen Westaby
    BMJ 334:167-8. 2007
  91. pmc To stent or not to stent?: A sterile debate
    Stephen Westaby
    BMJ 335:111. 2007
  92. doi request reprint Aprotinin: twenty-five years of claim and counterclaim
    Stephen Westaby
    J Thorac Cardiovasc Surg 135:487-91. 2008
  93. pmc Penetrating cardiac injury
    Elias Degiannis
    Trauma Department, Chris Hani Baragwanath Hospital, University of Witwatersrand Medical School, Johannesburg, South Africa
    Ann R Coll Surg Engl 87:61-3. 2005
  94. ncbi request reprint End-organ function during chronic nonpulsatile circulation
    Satoshi Saito
    Oxford Heart Centre and Department of Cellular Pathology, United Kingdom
    Ann Thorac Surg 74:1080-5. 2002
    ..We established consistently nonpulsatile blood flow in a sheep model using the Terumo magnetically suspended centrifugal pump. We then compared end-organ function between pulseless and control animals...
  95. ncbi request reprint Mechanical reliability of the Jarvik 2000 Heart
    Michael P Siegenthaler
    Center for Cardiovascular Disease, University of Freiburg, Freiburg, Germany
    Ann Thorac Surg 81:1752-8; discussion 1758-9. 2006
    ..Device failure is a limitation of permanent mechanical circulatory support. We studied the mechanical reliability of the Jarvik 2000 Heart, an axial flow pump with ceramic bearings designed to provide more than 10 years' durability...