J E Osborne

Summary

Country: UK

Publications

  1. doi request reprint Demographic and clinical correlates of extent of psoriasis during stable disease and during flares in chronic plaque psoriasis
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester, U K
    Br J Dermatol 158:721-6. 2008
  2. ncbi request reprint Skin cancer screening and surveillance
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
    Br J Dermatol 146:745-54. 2002
  3. ncbi request reprint Vitamin D and systemic cancer: is this relevant to malignant melanoma?
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    Br J Dermatol 147:197-213. 2002
  4. ncbi request reprint The importance of accurate dosage of topical agents: a method of estimating involved area and application to calcipotriol treatment failures
    J E Osborne
    The Department of Dermatology, Leicester Royal Infirmary, UK
    J Eur Acad Dermatol Venereol 16:367-73. 2002
  5. ncbi request reprint Comparison of diagnostic accuracy for cutaneous malignant melanoma between general dermatology, plastic surgery and pigmented lesion clinics
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    Br J Dermatol 148:252-8. 2003
  6. ncbi request reprint Vitamin D receptor gene polymorphisms, particularly the novel A-1012G promoter polymorphism, are associated with vitamin D3 responsiveness and non-familial susceptibility in psoriasis
    J A Halsall
    Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK
    Pharmacogenet Genomics 15:349-55. 2005
  7. ncbi request reprint Clinical correlates of Breslow thickness of malignant melanoma
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester, LE1 5WW U.K
    Br J Dermatol 144:476-83. 2001
  8. ncbi request reprint A follow-up study to investigate the efficacy of initial treatment of lentigo maligna with surgical excision
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester, UK
    Br J Plast Surg 55:611-5. 2002
  9. pmc A novel polymorphism in the 1A promoter region of the vitamin D receptor is associated with altered susceptibilty and prognosis in malignant melanoma
    J A Halsall
    Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK
    Br J Cancer 91:765-70. 2004
  10. ncbi request reprint Loss of beta-catenin expression is associated with disease progression in malignant melanoma
    J E Osborne
    Br J Dermatol 146:1104. 2002

Collaborators

Detail Information

Publications15

  1. doi request reprint Demographic and clinical correlates of extent of psoriasis during stable disease and during flares in chronic plaque psoriasis
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester, U K
    Br J Dermatol 158:721-6. 2008
    ..Following a previous population-based study, we define a common psoriatic phenotype (A) with a limited area of involvement of stable disease but extensive flares and a less common phenotype (B) with consistently widespread disease...
  2. ncbi request reprint Skin cancer screening and surveillance
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
    Br J Dermatol 146:745-54. 2002
  3. ncbi request reprint Vitamin D and systemic cancer: is this relevant to malignant melanoma?
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    Br J Dermatol 147:197-213. 2002
    ..Meanwhile, it would seem mandatory to ensure an adequate vitamin D3 status if sun exposure were seriously curtailed, certainly in relation to carcinoma of breast, prostate and colon and probably also MM...
  4. ncbi request reprint The importance of accurate dosage of topical agents: a method of estimating involved area and application to calcipotriol treatment failures
    J E Osborne
    The Department of Dermatology, Leicester Royal Infirmary, UK
    J Eur Acad Dermatol Venereol 16:367-73. 2002
    ..0001). The frequency distribution of the PASI reduction defined responsive (70% of patients) and poorly responsive groups (30%), with mean PASI reduction of 60% and 17%, respectively...
  5. ncbi request reprint Comparison of diagnostic accuracy for cutaneous malignant melanoma between general dermatology, plastic surgery and pigmented lesion clinics
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    Br J Dermatol 148:252-8. 2003
    ..Since the 1980s there have been dedicated pigmented lesion clinics (PLCs) in the U.K. Important considerations when comparing the efficacy of the PLC with other referral clinics include diagnostic accuracy...
  6. ncbi request reprint Vitamin D receptor gene polymorphisms, particularly the novel A-1012G promoter polymorphism, are associated with vitamin D3 responsiveness and non-familial susceptibility in psoriasis
    J A Halsall
    Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK
    Pharmacogenet Genomics 15:349-55. 2005
    ..In conclusion, the A-1012G, Fok1 and Taq1 VDR polymorphisms were associated with response to calcipotriol. A-1012G and Fok1 were associated with susceptibility to non-familial psoriasis...
  7. ncbi request reprint Clinical correlates of Breslow thickness of malignant melanoma
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester, LE1 5WW U.K
    Br J Dermatol 144:476-83. 2001
    ....
  8. ncbi request reprint A follow-up study to investigate the efficacy of initial treatment of lentigo maligna with surgical excision
    J E Osborne
    Department of Dermatology, Leicester Royal Infirmary, Leicester, UK
    Br J Plast Surg 55:611-5. 2002
    ..The high rate calls into question the accuracy of the routine histological assessment of clearance. The development of LMM was rare following surgery...
  9. pmc A novel polymorphism in the 1A promoter region of the vitamin D receptor is associated with altered susceptibilty and prognosis in malignant melanoma
    J A Halsall
    Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK
    Br J Cancer 91:765-70. 2004
    ..025) and the Fok 1 variant enhanced the effect of the A allele of the A-1012G polymorphism on metastasis, the probability of metastasis for AAff at 5 years follow-up being 57%, CI 24-92%...
  10. ncbi request reprint Loss of beta-catenin expression is associated with disease progression in malignant melanoma
    J E Osborne
    Br J Dermatol 146:1104. 2002
  11. ncbi request reprint Longitudinal melanonychia and pseudo-Hutchinson sign associated with amlodipine
    M J Sladden
    Br J Dermatol 153:219-20. 2005
  12. ncbi request reprint Fumaric acid esters for severe psoriasis: the Leicestershire experience
    M J Sladden
    Br J Dermatol 155:843-4. 2006
  13. ncbi request reprint In silico analysis of the 5' region of the Vitamin D receptor gene: functional implications of evolutionary conservation
    J A Halsall
    Department of Cancer Studies and Molecular Medicine, University of Leicester, Level 3, Robert Kilpatrick Clinical Sciences Building, Leicester LE2 7LX, UK
    J Steroid Biochem Mol Biol 103:352-6. 2007
    ..No significant clusters of conserved sites were observed in the 1c promoter region, despite reports of 1c promoter activity...
  14. ncbi request reprint Do we need a revised public health policy on sun exposure?
    P E Hutchinson
    Br J Dermatol 156:786-8; author reply 788. 2007
  15. ncbi request reprint Palatal surgery for snoring: objective long-term evaluation
    E Z Osman
    Department of Otolaryngology, Glan Clwyd Hospital, Rhyl, Denbighshire, UK
    Clin Otolaryngol Allied Sci 28:257-61. 2003
    ..This study is the first to use postoperative objective assessment in the home and to demonstrate that snoring reduction is maintained for several years after snoring surgery...