D A O'Reilly

Summary

Country: UK

Publications

  1. ncbi Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis
    B Yang
    Molecular Medicine Research Group, Plymouth Postgraduate Medical School, ITTC Building, University of Plymouth, Tamar Science Park, Derriford Road, PL6 8BX, Plymouth, UK
    Alcohol 23:91-7. 2001
  2. ncbi Radiofrequency ablation of colorectal liver metastases: where are we really going?
    Graeme J Poston
    J Clin Oncol 23:1342-4. 2005
  3. doi Perioperative use of the LiMON method of indocyanine green elimination measurement for the prediction and early detection of post-hepatectomy liver failure
    N De Liguori Carino
    Supra Regional Hepatobiliary Unit, University Hospital Aintree, Liverpool, L9 7AL, UK
    Eur J Surg Oncol 35:957-62. 2009
  4. pmc The clinical course of acute pancreatitis and the inflammatory mediators that drive it
    Leena Kylanpaa
    Department of Surgery, Helsinki University Central Hospital, Haartmaninkatu 4, 00290 Helsinki, Finland
    Int J Inflam 2012:360685. 2012
  5. doi The SPINK1 N34S variant is associated with acute pancreatitis
    Derek A O'Reilly
    Department of Surgery, Derriford Hospital, University of Plymouth, Plymouth, UK
    Eur J Gastroenterol Hepatol 20:726-31. 2008
  6. ncbi The Oncosurge strategy for the management of colorectal liver metastases - an external validation study
    D A O'Reilly
    Department of Surgery, University Hospital Aintree, Lower Lane, Liverpool, L9 7AL, UK
    Eur J Surg Oncol 34:538-40. 2008
  7. ncbi Colorectal liver metastases: current and future perspectives
    Derek A O'Reilly
    Liverpool Supra Regional Hepato Biliary Centre, University Hospital Aintree, Liverpool, L9 7AL, UK
    Future Oncol 2:525-31. 2006
  8. ncbi Heat shock factor-1 and nuclear factor-kappaB are systemically activated in human acute pancreatitis
    Derek A O'Reilly
    Department of Surgery, Derriford Hospital, Plymouth, United Kingdom
    JOP 7:174-84. 2006
  9. ncbi Tumour necrosis factor microsatellite haplotypes are associated with chronic pancreatitis
    Derek A O'Reilly
    Department of Surgery, Derriford Hospital, Plymouth, United Kingdom
    JOP 7:14-26. 2006
  10. ncbi NFkappaB polymorphisms and susceptibility to type 1 diabetes
    D M Hegazy
    Department of Molecular Medicine, Postgraduate Medical School, University of Plymouth, Plymouth PL6 8BX, UK
    Genes Immun 2:304-8. 2001

Detail Information

Publications23

  1. ncbi Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis
    B Yang
    Molecular Medicine Research Group, Plymouth Postgraduate Medical School, ITTC Building, University of Plymouth, Tamar Science Park, Derriford Road, PL6 8BX, Plymouth, UK
    Alcohol 23:91-7. 2001
    ..Therefore, our study results suggest to us that the polymorphisms investigated in the CYP2E1 gene are unlikely to be involved in the susceptibility and pathogenesis of alcoholic pancreatitis...
  2. ncbi Radiofrequency ablation of colorectal liver metastases: where are we really going?
    Graeme J Poston
    J Clin Oncol 23:1342-4. 2005
  3. doi Perioperative use of the LiMON method of indocyanine green elimination measurement for the prediction and early detection of post-hepatectomy liver failure
    N De Liguori Carino
    Supra Regional Hepatobiliary Unit, University Hospital Aintree, Liverpool, L9 7AL, UK
    Eur J Surg Oncol 35:957-62. 2009
    ..The aim was to assess the relationship between pre and post-operative ICG plasma disappearance rate (ICG PDR %/min) values and the onset of post-hepatectomy liver dysfunction...
  4. pmc The clinical course of acute pancreatitis and the inflammatory mediators that drive it
    Leena Kylanpaa
    Department of Surgery, Helsinki University Central Hospital, Haartmaninkatu 4, 00290 Helsinki, Finland
    Int J Inflam 2012:360685. 2012
    ..Also, increasing the understanding of the pathogenesis of systemic inflammation and the development of organ dysfunction may provide us with future treatment modalities...
  5. doi The SPINK1 N34S variant is associated with acute pancreatitis
    Derek A O'Reilly
    Department of Surgery, Derriford Hospital, University of Plymouth, Plymouth, UK
    Eur J Gastroenterol Hepatol 20:726-31. 2008
    ..The aim of this study was to investigate the prevalence of genetic variants of the trypsin inhibitor, SPINK1, in acute pancreatitis...
  6. ncbi The Oncosurge strategy for the management of colorectal liver metastases - an external validation study
    D A O'Reilly
    Department of Surgery, University Hospital Aintree, Lower Lane, Liverpool, L9 7AL, UK
    Eur J Surg Oncol 34:538-40. 2008
    ....
  7. ncbi Colorectal liver metastases: current and future perspectives
    Derek A O'Reilly
    Liverpool Supra Regional Hepato Biliary Centre, University Hospital Aintree, Liverpool, L9 7AL, UK
    Future Oncol 2:525-31. 2006
    ....
  8. ncbi Heat shock factor-1 and nuclear factor-kappaB are systemically activated in human acute pancreatitis
    Derek A O'Reilly
    Department of Surgery, Derriford Hospital, Plymouth, United Kingdom
    JOP 7:174-84. 2006
    ..Both are attractive therapeutic targets, undergoing investigation in other acute inflammatory conditions, such as sepsis...
  9. ncbi Tumour necrosis factor microsatellite haplotypes are associated with chronic pancreatitis
    Derek A O'Reilly
    Department of Surgery, Derriford Hospital, Plymouth, United Kingdom
    JOP 7:14-26. 2006
    ..However, as only a minority of alcoholics develop either chronic pancreatitis or alcoholic liver disease, there are clearly genetic or environmental cofactors that determine individual susceptibility to these diseases...
  10. ncbi NFkappaB polymorphisms and susceptibility to type 1 diabetes
    D M Hegazy
    Department of Molecular Medicine, Postgraduate Medical School, University of Plymouth, Plymouth PL6 8BX, UK
    Genes Immun 2:304-8. 2001
    ..8, P < 0.00000). These results demonstrate that the NFkappaB gene may play a role in the susceptibility to type 1 diabetes: individuals with the A10 allele may be more likely to develop diabetes compared with the A14 allele...
  11. ncbi Mutations of the cationic trypsinogen gene in hereditary and non-hereditary pancreatitis
    D A O'Reilly
    Department of Surgery, Derriford Hospital and University of Plymouth, UK
    Digestion 64:54-60. 2001
    ..This study investigates the prevalence of the R122H, N29I, A16V and -28delTCC mutations in the common, non-hereditary forms of chronic pancreatitis and in a HP family...
  12. pmc The prognostic significance of the preoperative full blood count after resection of colorectal liver metastases
    K Dajani
    Department of Surgery, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UK
    HPB Surg 2009:425065. 2009
    ..Our aim was to investigate the relationship between overall or disease-free survival after resection of CRLM and the preoperative haematological parameters...
  13. pmc Extensive necrosis of visceral melanoma metastases after immunotherapy
    David Stoeter
    The Department of Hepatobiliary Surgery, Aintree University Hospital NHS Foundation Trust, Lower Lane, Fazakerley, Liverpool, L9 7AL, UK
    World J Surg Oncol 6:30. 2008
    ..A toll-like receptor 9 agonist, PF-3512676 (formerly known as CPG 7909) is currently being evaluated for its potential...
  14. ncbi Muir-Torre syndrome: a case for surveillance of the ampulla of Vater
    J J Matthews
    Department of Surgery, Derriford Hospital, Plymouth, UK
    Dig Surg 19:65-6. 2002
    ..As an ampullary carcinoma is potentially amenable to surgical resection, particularly when detected early, patients with MTS should undergo regular endoscopic surveillance of the ampulla of Vater...
  15. ncbi Surgical strategies for colorectal liver metastases
    Graeme J Poston
    Liverpool Supra Regional Hepato Biliary Center, University Hospital, Aintree, Liverpool L9, UK Royal Liverpool University Hospital, Liverpool, UK
    Surg Oncol 13:125-36. 2004
    ..Therefore, in 2004 nearly one third of patients with disease confined to the liver can now look forward to possibly curative liver surgery...
  16. doi Staging of advanced colorectal cancer
    Graeme J Poston
    Division of Digestive Diseases, Critical Care and Anesthesia, Center for Digestive Diseases, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UK
    Surg Oncol Clin N Am 17:503-17, viii. 2008
    ..This article discusses the merits of a number of proposals for a new, meaningful staging system for advanced colorectal cancer...
  17. doi Urgent need for a new staging system in advanced colorectal cancer
    Graeme J Poston
    Department of Surgery, University Hospital Aintree, Liverpool, L9 7AL, United Kingdom
    J Clin Oncol 26:4828-33. 2008
    ....
  18. doi Liver resection for colorectal liver metastases in older patients
    Nicola De Liguori Carino
    Supra Regional Hepatobiliary Unit, University Hospital Aintree, Liverpool L97AL, UK
    Crit Rev Oncol Hematol 67:273-8. 2008
    ..This study was conducted to investigate both the feasibility, and short- and long-term outcomes of liver resection for colorectal liver metastases in elderly patients...
  19. ncbi Biopsy of solid liver tumors: adverse consequences
    Dhya Al-Leswas
    Department of Surgery, University Hospital Aintree, Lower Lane, Liverpool, L9 7AL, UK
    Hepatobiliary Pancreat Dis Int 7:325-7. 2008
    ..While it has an undoubted role in the investigation and management of acute and chronic inflammatory conditions of the liver, its role in hepatic oncology is doubtful and probably dangerous...
  20. ncbi OncoSurge: a strategy for improving resectability with curative intent in metastatic colorectal cancer
    Graeme J Poston
    Department of Surgery, Royal Liverpool University Hospital, Liverpool L7 8XP, UK
    J Clin Oncol 23:7125-34. 2005
    ..Since treatment strategy is frequently dependent on the response to earlier treatments, our aim was to create a therapeutic decision model identifying appropriate procedure sequences...
  21. pmc Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial
    Bernard Nordlinger
    centre hospitalier universitaire Ambroise Paré, Assistance Publique Hopitaux de Paris, Departments of Surgery and Oncology, Boulogne Billancourt, France
    Lancet 371:1007-16. 2008
    ..We assessed the combination of perioperative chemotherapy and surgery compared with surgery alone for patients with initially resectable liver metastases from colorectal cancer...
  22. ncbi Decision making for patients with colorectal cancer liver metastases
    Graeme J Poston
    Ann Surg Oncol 13:10-1. 2006