J S Elborn

Summary

Affiliation: Northern Ireland
Country: UK

Publications

  1. ncbi Staphylococcus aureus enterotoxins induce IL-8 secretion by human nasal epithelial cells
    Garrett J O'Brien
    Respiratory Research Group, School of Medicine and Dentistry, Queen s University Belfast, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland, UK
    Respir Res 7:115. 2006
  2. ncbi Elective versus symptomatic antibiotic treatment in cystic fibrosis patients with chronic Pseudomonas infection of the lungs
    J S Elborn
    Thorax 55:355-8. 2000
  3. ncbi Practical management of cystic fibrosis
    J S Elborn
    Respiratory Medicine Group, Queens' University of Belfast, Belfast, N. Ireland
    Chron Respir Dis 3:161-5. 2006
  4. ncbi Implementation of European standards of care for cystic fibrosis--control and treatment of infection
    J S Elborn
    Respiratory Medicine Research Group, Queen s University, Belfast City Hospital, Ground Floor, Lisburn Rd, Belfast, BT9 7AB, UK
    J Cyst Fibros 8:211-7. 2009
  5. ncbi Implementation of European standards of care for cystic fibrosis - provision of care
    J S Elborn
    Centre for Infection an Immunity, Queen s University, Belfast City Hospital, UK
    J Cyst Fibros 8:348-55. 2009
  6. ncbi Non-tuberculous mycobacterial infection in adult patients with cystic fibrosis: comparison of three decontamination methods
    R W Jordan
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Lisburn Road, Belfast, Northern Ireland, UK
    Br J Biomed Sci 65:28-30. 2008
  7. ncbi Molecular epidemiology of Pseudomonas aeruginosa in adult patients with cystic fibrosis in Northern Ireland
    L Clarke
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK
    Br J Biomed Sci 65:18-21. 2008
  8. ncbi Improved cultural detection of Burkholderia cepacia from sputum in patients with cystic fibrosis
    R M Wright
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, Northern Ireland, UK
    J Clin Pathol 54:803-5. 2001
  9. ncbi PCR-based detection and identification of Burkholderia cepacia complex pathogens in sputum from cystic fibrosis patients
    A McDowell
    Molecular Epidemiology Research Unit, Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, United Kingdom BT9 7AB
    J Clin Microbiol 39:4247-55. 2001
  10. ncbi Molecular (PCR) detection of Pseudomonas spp. other than P. aeruginosa directly from the sputum of adults and children with cystic fibrosis
    J Xu
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Lisburn Road, Northern Ireland, UK
    Br J Biomed Sci 61:147-9. 2004

Collaborators

Detail Information

Publications70

  1. ncbi Staphylococcus aureus enterotoxins induce IL-8 secretion by human nasal epithelial cells
    Garrett J O'Brien
    Respiratory Research Group, School of Medicine and Dentistry, Queen s University Belfast, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland, UK
    Respir Res 7:115. 2006
    ..Staphylococcus aureus produces a set of proteins which act both as superantigens and toxins. Although their mode of action as superantigens is well understood, little is known about their effects on airway epithelial cells...
  2. ncbi Elective versus symptomatic antibiotic treatment in cystic fibrosis patients with chronic Pseudomonas infection of the lungs
    J S Elborn
    Thorax 55:355-8. 2000
    ..The results of a prospective multicentre study to compare the effects on pulmonary function and mortality of three monthly elective anti-pseudomonal antibiotic treatment with conventional symptomatic treatment are reported...
  3. ncbi Practical management of cystic fibrosis
    J S Elborn
    Respiratory Medicine Group, Queens' University of Belfast, Belfast, N. Ireland
    Chron Respir Dis 3:161-5. 2006
  4. ncbi Implementation of European standards of care for cystic fibrosis--control and treatment of infection
    J S Elborn
    Respiratory Medicine Research Group, Queen s University, Belfast City Hospital, Ground Floor, Lisburn Rd, Belfast, BT9 7AB, UK
    J Cyst Fibros 8:211-7. 2009
    ..Several guidelines on infection control and treatment of infection exist for cystic fibrosis (CF) caregivers, although the extent of implementation is variable...
  5. ncbi Implementation of European standards of care for cystic fibrosis - provision of care
    J S Elborn
    Centre for Infection an Immunity, Queen s University, Belfast City Hospital, UK
    J Cyst Fibros 8:348-55. 2009
    ..Several guidelines for cystic fibrosis (CF) caregivers exist, but information about their implementation is lacking...
  6. ncbi Non-tuberculous mycobacterial infection in adult patients with cystic fibrosis: comparison of three decontamination methods
    R W Jordan
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Lisburn Road, Belfast, Northern Ireland, UK
    Br J Biomed Sci 65:28-30. 2008
  7. ncbi Molecular epidemiology of Pseudomonas aeruginosa in adult patients with cystic fibrosis in Northern Ireland
    L Clarke
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK
    Br J Biomed Sci 65:18-21. 2008
    ..Resulting banding patterns showed a high degree of genetic heterogeneity among all isolates from the patients examined, suggesting a non-clonal relationship between isolates from these patients, when employing this genotyping technique...
  8. ncbi Improved cultural detection of Burkholderia cepacia from sputum in patients with cystic fibrosis
    R M Wright
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, Northern Ireland, UK
    J Clin Pathol 54:803-5. 2001
    ..However, its present limited commercial availability in the UK may delay its use in routine diagnostic laboratories because of complications with media preparation and quality control...
  9. ncbi PCR-based detection and identification of Burkholderia cepacia complex pathogens in sputum from cystic fibrosis patients
    A McDowell
    Molecular Epidemiology Research Unit, Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, United Kingdom BT9 7AB
    J Clin Microbiol 39:4247-55. 2001
    ..cepacia complex genomovars directly from sputum. Where the sensitivity of the assay proves a limitation, sputum samples can be analyzed by selective culturing followed by recA-based analysis of the isolate...
  10. ncbi Molecular (PCR) detection of Pseudomonas spp. other than P. aeruginosa directly from the sputum of adults and children with cystic fibrosis
    J Xu
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Lisburn Road, Northern Ireland, UK
    Br J Biomed Sci 61:147-9. 2004
  11. ncbi Non-coding small (micro) RNAs of Pseudomonas aeruginosa isolated from clinical isolates from adult patients with cystic fibrosis
    J R Rao
    Molecular Diagnostics and Environmental Health, Agri Food and Biosciehces Institute, Belfast, Northern Ireland, UK
    Br J Biomed Sci 67:126-32. 2010
    ....
  12. ncbi Predictors of mortality in adults with cystic fibrosis
    J M Courtney
    Adult Cystic Fibrosis Unit, Belfast City Hospital, Belfast, Northern Ireland, Ireland
    Pediatr Pulmonol 42:525-32. 2007
    ..aeruginosa or B.cepacia complex. FEV(1)% and infection with P.aeruginosa or B.cepacia complex were the most significant predictors of survival in adults with CF...
  13. ncbi Bacterial contaminants in cosmetic products from a patient with cystic fibrosis
    J Xu
    Northern Ireland Public Health Laboratory, Department of Bacteriology, The Queen's University of Belfast, Respiratory Medicine, Belfast City Hospital, Lisburn Road, Belfast, Northern Ireland BT9 7AB
    Br J Biomed Sci 63:141-2. 2006
  14. ncbi A comparison of pulmonary exacerbations with single and multiple organisms in patients with cystic fibrosis and chronic Burkholderia cepacia infection
    T E Mc Manus
    Belfast City Hospital, Lisburn Road Belfast, Northern Ireland, BT9 7AB
    J Infect 46:56-9. 2003
    ..To compare pulmonary exacerbations with single and multiple organisms in patients with chronic Burkholderia cepacia infection...
  15. ncbi Quality of life and inflammation in exacerbations of bronchiectasis
    J M Courtney
    Respiratory Research Centre, Belfast City Hospital, Belfast, Northern Ireland
    Chron Respir Dis 5:161-8. 2008
    ..The improvements in QoL scores could not be explained by the improvements in lung function or inflammatory markers...
  16. ncbi Sputum antibiotic concentrations: implications for treatment of cystic fibrosis lung infection
    T F Moriarty
    The Clinical and Practice Research Group, School of Pharmacy, Queen s University Belfast, Belfast, UK
    Pediatr Pulmonol 42:1008-17. 2007
    ....
  17. ncbi Reduction in neutrophil elastase concentration by recombinant alphal-antitrypsin (recAAT) does not alter bacterial loading in the sputum of cystic fibrosis patients
    J E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Northern Ireland, UK
    Br J Biomed Sci 61:146-7. 2004
  18. ncbi Cytokine concentrations and neutrophil elastase activity in bronchoalveolar lavage and induced sputum from patients with cystic fibrosis, mild asthma and healthy volunteers
    L P A McGarvey
    Department of Respiratory Medicine, Level 8, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, Northern Ireland, UK
    J Cyst Fibros 1:269-75. 2002
    ..The aim of this study was to compare both methods in patients with cystic fibrosis (CF). The possible differences between subjects with CF, mild asthma and healthy volunteers (HV) was also assessed...
  19. ncbi Rapid characterization of the genomovars of the Burkholderia cepacia complex by PCR-single-stranded conformational polymorphism (PCR-SSCP) analysis
    J E Moore
    Department of Bacteriology, Northern Ireland Public Health Laboratory, Belfast, BT9 7AD, UK
    J Hosp Infect 48:129-34. 2001
    ..SSCP analysis was demonstrated to be simple, rapid and cost effective and may prove a useful method of genomovar typing of B. cepacia complex organisms from cystic fibrosis patients in busy diagnostic laboratories...
  20. ncbi Molecular detection and identification of Cryptosporidium species in lettuce employing nested small-subunit rRNA PCR and direct automated sequencing
    M Shigematsu
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland
    Br J Biomed Sci 64:133-5. 2007
  21. ncbi Development of a genus-specific PCR assay for the molecular detection, confirmation and identification of Fusobacterium spp
    Y Nagano
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, UK
    Br J Biomed Sci 64:74-7. 2007
    ..in the faeces of eight (10%) out of 80 patients with suspected gastrointestinal infection. This assay may be used for the genus-specific detection of Fusobacterium spp. from clinical specimens and for subsequent species identification...
  22. ncbi Association of airway cathepsin B and S with inflammation in cystic fibrosis
    S L Martin
    School of Pharmacy, Queen s University, Belfast, UK
    Pediatr Pulmonol 45:860-8. 2010
    ..This data indicates that cathepsin B and S may have important roles in the pathophysiology of CF lung disease and could have potential as markers of inflammation in future studies...
  23. ncbi Long-term preservation of strains of Burkholderia cepacia, Pseudomonas spp. and Stenotrophomonas maltophilia isolated from patients with cystic fibrosis
    J E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, UK
    Lett Appl Microbiol 33:82-3. 2001
    ..An effective and cheap storage method using debrinated blood and maintenance at -80 degrees C is described...
  24. ncbi Development of a Gram-negative selective agar (GNSA) for the detection of Gram-negative microflora in sputa in patients with cystic fibrosis
    J E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, UK
    J Appl Microbiol 95:160-6. 2003
    ..To develop a selective agar medium to help detect and quantify Gram-negative flora in the sputum of patients with cystic fibrosis (CF)...
  25. ncbi Occurrence of Burkholderia cepacia in foods and waters: clinical implications for patients with cystic fibrosis
    J E Moore
    Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK
    J Food Prot 64:1076-8. 2001
    ..In addition to the associated risk of infection from fecal pathogens, patients with cystic fibrosis should therefore avoid the consumption of raw unpasteurized milk to minimize the risk of becoming infected with this organism...
  26. ncbi Aquagenic wrinkling of the palms in an adult cystic fibrosis population
    J P Tolland
    Department of Dermatology, Ulster Hospital, Dundonald, Belfast, UK
    Dermatology 221:326-30. 2010
    ..It has frequently been associated with cystic fibrosis (CF). Early reports of AWP have only been case reports or small case series; there has only been one reported prevalence study of AWP in a CF population...
  27. ncbi Clinical phenotype of cystic fibrosis patients with the G551D mutation
    D M Comer
    Regional Adult Cystic Fibrosis Centre, Belfast City Hospital, Belfast, N Ireland, Antrim BT9 7AB, UK
    QJM 102:793-8. 2009
    ..Data on whether the phenotype of cystic fibrosis (CF) patients with compound heterozygocity for G551D (Gly551Asp) differs from patients with F508del (Phe508del) homozygous mutations is divergent...
  28. ncbi Effect of oxygen limitation on the in vitro antimicrobial susceptibility of clinical isolates of Pseudomonas aeruginosa grown planktonically and as biofilms
    T R Field
    Clinical and Practice Research Group, School of Pharmacy, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, BT9 7BL, UK
    Eur J Clin Microbiol Infect Dis 24:677-87. 2005
    ..These results show that oxygen limitation may reduce, in a strain-dependent manner, the susceptibility to tobramycin of P. aeruginosa grown planktonically and as biofilms...
  29. ncbi Clinical outcome of Burkholderia cepacia complex infection in cystic fibrosis adults
    J M Courtney
    Adult Cystic Fibrosis Centre, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, North Ireland, UK
    J Cyst Fibros 3:93-8. 2004
    ..Infection with a single B. cenocepacia strain was associated with a more rapid decline in lung function than those infected with either B. multivorans or P. aeruginosa...
  30. ncbi Atypical mycobacterial infection in patients with cystic fibrosis: update on clinical microbiology methods
    P W Jordan
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK
    Lett Appl Microbiol 44:459-66. 2007
    ....
  31. ncbi Occurrence of Cryptosporidium parvum and bacterial pathogens in faecal material in the red fox (Vulpes vulpes) population
    Y Nagano
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, UK
    Vet Res Commun 31:559-64. 2007
  32. ncbi Cytokines and inflammatory mediators in cystic fibrosis
    J M Courtney
    Adult Cystic Fibrosis Centre, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, Northern Ireland, UK
    J Cyst Fibros 3:223-31. 2004
    ..However, the relationship between this unbalanced cytokine production, the mutations in CFTR and its actual consequence for pathogenesis need further investigation...
  33. ncbi Development of primary human nasal epithelial cell cultures for the study of cystic fibrosis pathophysiology
    F de Courcey
    Centre for Infection and Immunity, Queen s University Belfast, Health Sciences Building, Belfast, UK
    Am J Physiol Cell Physiol 303:C1173-9. 2012
    ..Thus nasal epithelial cells from patients with CF can be grown from nasal brushings and used in electrophysiological and mediator release studies in CF research...
  34. ncbi Proposed definitions of community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA)
    B C Millar
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, UK
    J Hosp Infect 67:109-13. 2007
    ..The aim of this article is to highlight the differences between HA-MRSA and CA-MRSA and to propose standard definitions of the various subgroups of CA-MRSA...
  35. ncbi Neutrophil apoptosis, proinflammatory mediators and cell counts in bronchiectasis
    A P Watt
    Respiratory Research Group, Centre for Infection, Inflammation and Repair, The Queen s University of Belfast, Belfast, UK
    Thorax 59:231-6. 2004
    ..The aim of this study was to investigate the effects of antibiotic treatment for exacerbations on neutrophil apoptosis and necrosis...
  36. ncbi Misidentification of a genomovar of Burkholderia cepacia by recA restriction fragment length polymorphism
    J E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast BT9 7AD, Northern Ireland, UK
    J Clin Pathol 55:309-11. 2002
    ....
  37. ncbi Employment of 16 S rDNA gene sequencing techniques to identify culturable environmental eubacteria in a tertiary referral hospital
    J Xu
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Northern Ireland, UK
    J Hosp Infect 57:52-8. 2004
    ..Where molecular identification methods are justified, partial 16 S rDNA PCR and sequencing employing the novel universal primer XB4, is a valuable and reliable technique...
  38. ncbi Self-management in bronchiectasis: the patients' perspective
    K Lavery
    Dept of Respiratory Medicine, Belfast City Hospital, UK
    Eur Respir J 29:541-7. 2007
    ..The present study has provided information from the patients' perspective of elements which need to be included in a successful disease-specific self-management programme...
  39. ncbi Obesity and the lung: 1. Epidemiology
    K M McClean
    Queen s University of Belfast, Belfast, UK
    Thorax 63:649-54. 2008
    ..Healthcare planners should consider the impact of obesity for future resources in respiratory care...
  40. ncbi Admissions with chronic obstructive pulmonary disease after publication of national guidelines
    M G Kelly
    Department of Respiratory Medicine, Belfast City Hospital, Belfast, Northern Ireland
    Ir J Med Sci 171:16-9. 2002
    ..The British Thoracic Society (BTS) published guidelines on managing acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in 1997...
  41. ncbi Effect of pH on the antimicrobial susceptibility of planktonic and biofilm-grown clinical Pseudomonas aeruginosa isolates
    T F Moriarty
    Clinical and Practice Research Group, School of Pharmacy, Queen s University Belfast, Northern Ireland
    Br J Biomed Sci 64:101-4. 2007
    ..These results show that growth in an acidic environment may reduce the susceptibility of clinical P. aeruginosa isolates to tobramycin...
  42. ncbi Exacerbations in cystic fibrosis: 3--Management
    A Smyth
    Department of Child Health, University of Nottingham, Nottingham, UK
    Thorax 63:180-4. 2008
    ..The aetiology of these exacerbations is discussed, together with the options for treatment and the evidence to support treatment choices...
  43. ncbi Inflammatory related changes in bone mineral content in adults with cystic fibrosis
    C S Haworth
    Department of Medicine, University of Manchester, Manchester Royal Infirmary, Manchester M13 9WL, UK
    Thorax 59:613-7. 2004
    ..011) were independently significant predictors of annual change in BMC. CONCLUSIONS: These data suggest a pathophysiological mechanism by which chronic pulmonary infection results in bone loss in patients with cystic fibrosis...
  44. ncbi Occurrence of Burkholderia cepacia in the hospital environment
    J E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Northern Ireland
    Ir J Med Sci 171:131-3. 2002
    ..To determine the prevalence of Burkholderia cepacia from the environment in a regional adult cystic fibrosis (CF) care centre...
  45. ncbi Comparison of in vitro susceptibilities to levofloxacin and ciprofloxacin with Pseudomonas aeruginosa and Stenotrophomonas maltophilia isolated from cystic fibrosis patients in Northern Ireland
    A J McKnight
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Northern Ireland
    Br J Biomed Sci 62:30-2. 2005
  46. ncbi Cystic fibrosis genotype and bacterial infection: a possible connection
    T E McManus
    Regional Adult Cystic Fibrosis Centre, Regional Genetics Laboratories Belfast City Hospital, Belfast, Northern Ireland BT9 7AB
    Br J Biomed Sci 62:85-8. 2005
    ..aeruginosa, with increased numbers of positive sputum cultures and infecting organisms. Those with the R117H mutation are less likely to be colonised by Gram-negative organisms...
  47. ncbi Inflammatory markers in cystic fibrosis patients with transmissible Pseudomonas aeruginosa
    A M Jones
    Manchester Adult Cystic Fibrosis Centre, South Manchester University Hospitals NHS Trust, Manchester, UK
    Eur Respir J 22:503-6. 2003
    ..At times of clinical stability, cystic fibrosis patients infected with transmissible Pseudomonas aeruginosa do not have a heightened inflammatory response above that of those harbouring sporadic strains...
  48. ncbi Burkholderia cepacia from a sink drain
    J E Moore
    J Hosp Infect 50:235-7. 2002
  49. ncbi Burkholderia cepacia and cystic fibrosis--50 years on
    J E Moore
    Northern Ireland Regional Adult Cystic Fibrosis Centre, Belfast City Hospital
    Commun Dis Public Health 4:114-6. 2001
    ..This brief review highlights the transmission of B. cepacia through the cystic fibrosis patient population and looks at possible treatments and current patient management approaches...
  50. ncbi Clinical outcome after acquisition of Burkholderia cepacia in patients with cystic fibrosis
    M McCloskey
    Adult Cystic Fibrosis Unit, Belfast City Hospital, Northern Ireland
    Ir J Med Sci 170:28-31. 2001
    ..cepacia acquisition date was known was 6.1% per year versus 1.55% in Group 2 patients (p<0.05). CONCLUSIONS: Acquisition of B. cepacia may be a cause of, rather than a marker for, a decrease in pulmonary function...
  51. ncbi Total energy expenditure in stable patients with cystic fibrosis
    M McCloskey
    Adult and Paediatric Cystic Fibrosis Centres Belfast City Hospital and Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland
    Clin Nutr 20:235-41. 2001
    ....
  52. ncbi Consensus on the use and interpretation of cystic fibrosis mutation analysis in clinical practice
    C Castellani
    Cystic Fibrosis Centre, Ospedale Civile Maggiore, Verona, Italy
    J Cyst Fibros 7:179-96. 2008
    ..The importance of communication between clinicians and medical genetic laboratories is emphasized. The results of testing and their implications should be reported in a manner understandable to the clinicians caring for CF patients...
  53. ncbi Incontinence in adult females with cystic fibrosis: a Northern Ireland survey
    F Moran
    School of Rehabilitation Sciences, University of Ulster, Newtownabbey, UK
    Int J Clin Pract 57:182-3. 2003
    ..This study highlights that patients with CF are reluctant to seek treatment for incontinence despite the impact this condition can have...
  54. ncbi Cystic fibrosis and guidelines to assess significance of new colonisers?
    L Garske
    Ir J Med Sci 171:116-7. 2002
  55. ncbi Microbial ecology of the cystic fibrosis lung: does microflora type influence microbial loading?
    J E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Ireland
    Br J Biomed Sci 62:175-8. 2005
    ..Ultimately, a greater understanding of such interactions may allow the opportunity to manipulate the ecology of the lung to control otherwise problematic pathogens..
  56. ncbi "CF asthma": what is it and what do we do about it?
    I M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London SW3 6NP, UK
    Thorax 57:742-8. 2002
    ..This may not matter, however; the relevance lies in the possible approaches to treatment...
  57. ncbi Incidence of Pseudomonas aeruginosa in recreational and hydrotherapy pools
    J E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast BT9 7AD
    Commun Dis Public Health 5:23-6. 2002
    ..aeruginosa for susceptible patient groups, including patients with cystic fibrosis and bronchiectasis. This may vary depending on amenity type and public/private ownership of such amenities...
  58. ncbi Environmental persistence of Pseudomonas aeruginosa and Burkholderia multivorans in sea water: preliminary evidence of a viable but non-culturable state
    J E Moore
    Northern Ireland Public Health Laboratory, Department of Bacteriology
    Br J Biomed Sci 64:129-31. 2007
  59. ncbi Effect of reduced pH on inorganic polyphosphate accumulation by Burkholderia cepacia complex isolates
    T F Moriarty
    Clinical and Practice Research Group, School of Pharmacy, Queen's University Belfast, Belfast, Northern Ireland
    Lett Appl Microbiol 42:617-23. 2006
    ..SIGNIFICANCE AND IMPACT OF THE STUDY: Growth of Bcc in an acidic environment, such as that found in the lungs of CF patients may be influenced in part by polyP accumulation...
  60. ncbi Antibiotic resistance and identification of uncommon Gram-negative bacteria isolated from sputum of adult patients with cystic fibrosis
    C Gillow
    Northern Ireland Public Health Laboratory, Department of Bacteriology, UK
    Br J Biomed Sci 63:22-5. 2006
  61. ncbi Neutrophil cell death, activation and bacterial infection in cystic fibrosis
    A P Watt
    Respiratory Research Group, The Queen s University of Belfast, Grosvenor Road, Belfast BT12 6BJ, UK
    Thorax 60:659-64. 2005
    ..Neutrophil apoptosis is essential for the resolution of inflammation. This study assessed the relationship between levels of neutrophil apoptosis and sputum microbiology in matched clinically stable patients with CF...
  62. ncbi Difficult bacteria, antibiotic resistance and transmissibility in cystic fibrosis
    J S Elborn
    Thorax 59:914-5. 2004
  63. ncbi Glucocorticoids as an adjuvant treatment to intravenous antibiotics for cystic fibrosis pulmonary exacerbations: a UK Survey
    K L M Hester
    Adult CF Centre, Bristol Royal Infirmary, Bristol BS2 8HW, United Kingdom
    J Cyst Fibros 6:311-3. 2007
    ..This survey highlighted the need for a RCT which would examine the role of adjuvant corticosteroids to IV antibiotics in CF P EX...
  64. ncbi Pulmonary exacerbations in cystic fibrosis and bronchiectasis
    J S Elborn
    Thorax 62:288-90. 2007
  65. ncbi Flight assessment in patients with respiratory disease: hypoxic challenge testing vs. predictive equations
    S E Martin
    Health and Rehabilitation Sciences Research Institute, School of Health Sciences, University of Ulster, UK
    QJM 100:361-7. 2007
    ..Predictive equations have been proposed as a simpler alternative to hypoxic challenge testing (HCT) for determining the risk of in-flight hypoxia...
  66. ncbi Acapella versus 'usual airway clearance' during acute exacerbation in bronchiectasis: a randomized crossover trial
    J E Patterson
    Regional Respiratory Centre, Belfast City Hospital, and Physiotherapy, Health and Rehabilitation Sciences Research Institute, School of Health Sciences, University of Ulster, Northern Ireland
    Chron Respir Dis 4:67-74. 2007
    ..There were no significant between group differences in changes in lung function. This study demonstrates that the Acapella device may offer an acceptable, user-friendly method of airway clearance in patients with bronchiectasis...
  67. ncbi Detection of mycobacterial DNA from sputum of patients with cystic fibrosis
    M Devine
    Northern Ireland Public Health Laboratory, The Royal Belfast Hospital for Sick Children, Northern Ireland
    Ir J Med Sci 173:96-8. 2004
    ..Enhanced molecular screening will contribute in understanding their role as opportunistic pathogens in patients with worsening lung function...
  68. ncbi Low incidence of Neisseria meningitidis serogroups B and C in lower respiratory tract secretions in patients with cystic fibrosis
    K Dunbar
    Br J Biomed Sci 60:233. 2003
  69. ncbi Inquilinus limosus isolated from a cystic fibrosis patient: first UK report
    R P D Cooke
    Department of Medical Microbiology, District General Hospital, Eastbourne, East Sussex
    Br J Biomed Sci 64:127-9. 2007
  70. ncbi Diagnosing CF: sweat, blood and years
    J S Elborn
    Thorax 61:556-7. 2006