Jens Noraberg

Summary

Country: UK

Publications

  1. ncbi request reprint The developmental expression of fluorescent proteins in organotypic hippocampal slice cultures from transgenic mice and its use in the determination of excitotoxic neurodegeneration
    Jens Noraberg
    Anatomy and Neurobiology, University of Southern Denmark, Odense, Denmark
    Altern Lab Anim 35:61-70. 2007
  2. ncbi request reprint Long-term, repeated dose in vitro neurotoxicity of the glutamate receptor antagonist L-AP3, demonstrated in rat hippocampal slice cultures by using continuous propidium iodide incubation
    Bjarne W Kristensen
    Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Odense, Denmark
    Altern Lab Anim 35:211-21. 2007
  3. ncbi request reprint Organotypic brain slice cultures: an efficient and reliable method for neurotoxicological screening and mechanistic studies
    Jens Noraberg
    NeuroScreen ApS, Anatomy and Neurobiology, University of Southern Denmark, Winslowparken 21, 5000 Odense, Denmark
    Altern Lab Anim 32:329-37. 2004
  4. ncbi request reprint Neuroprotective effects of the AMPA antagonist PNQX in oxygen-glucose deprivation in mouse hippocampal slice cultures and global cerebral ischemia in gerbils
    Maria Montero
    Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winslowparken 21st, DK 5000 Odense C, Denmark
    Brain Res 1177:124-35. 2007
  5. ncbi request reprint Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures
    Maria Montero
    Department of Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winsløwparken 21 st, DK 5000 Odense C, Denmark
    Exp Neurol 204:106-17. 2007
  6. ncbi request reprint The GABAA receptor agonist THIP is neuroprotective in organotypic hippocampal slice cultures
    Bjarne W Kristensen
    Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winsløwparken 21, DK 5000 Odense C, Denmark
    Brain Res 973:303-6. 2003
  7. ncbi request reprint Colchicine induces apoptosis in organotypic hippocampal slice cultures
    Bjarne W Kristensen
    Department of Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winsløwparken 21, DK 5000 C, Odense, Denmark
    Brain Res 964:264-78. 2003
  8. ncbi request reprint Nuclear shrinkage and other markers of neuronal cell death after oxygen-glucose deprivation in rat hippocampal slice cultures
    Christian Bonde
    Anatomy and Neurobiology, University of Southern Denmark, Winslowparken 21, 5000 Odense C, Denmark
    Neurosci Lett 327:49-52. 2002
  9. doi request reprint Zbtb20-induced CA1 pyramidal neuron development and area enlargement in the cerebral midline cortex of mice
    Jakob V Nielsen
    Molecular Neurobiology Laboratory, Medical Biotechnology Center, Department of Molecular Medicine, University of Southern Denmark, J B Winslows Vej 25, DK 5000 Odense C, Denmark
    Cereb Cortex 20:1904-14. 2010
  10. ncbi request reprint Organotypic hippocampal slice cultures for studies of brain damage, neuroprotection and neurorepair
    Jens Noraberg
    Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Odense, Denmark
    Curr Drug Targets CNS Neurol Disord 4:435-52. 2005

Collaborators

Detail Information

Publications15

  1. ncbi request reprint The developmental expression of fluorescent proteins in organotypic hippocampal slice cultures from transgenic mice and its use in the determination of excitotoxic neurodegeneration
    Jens Noraberg
    Anatomy and Neurobiology, University of Southern Denmark, Odense, Denmark
    Altern Lab Anim 35:61-70. 2007
    ....
  2. ncbi request reprint Long-term, repeated dose in vitro neurotoxicity of the glutamate receptor antagonist L-AP3, demonstrated in rat hippocampal slice cultures by using continuous propidium iodide incubation
    Bjarne W Kristensen
    Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Odense, Denmark
    Altern Lab Anim 35:211-21. 2007
    ..It is concluded that continuous incubation of hippocampal slice cultures with PI is technically feasible for use in studies of inducible neuronal degeneration over time...
  3. ncbi request reprint Organotypic brain slice cultures: an efficient and reliable method for neurotoxicological screening and mechanistic studies
    Jens Noraberg
    NeuroScreen ApS, Anatomy and Neurobiology, University of Southern Denmark, Winslowparken 21, 5000 Odense, Denmark
    Altern Lab Anim 32:329-37. 2004
    ....
  4. ncbi request reprint Neuroprotective effects of the AMPA antagonist PNQX in oxygen-glucose deprivation in mouse hippocampal slice cultures and global cerebral ischemia in gerbils
    Maria Montero
    Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winslowparken 21st, DK 5000 Odense C, Denmark
    Brain Res 1177:124-35. 2007
    ..We conclude that, PNQX provided neuroprotection against both global cerebral ischemia in gerbils in vivo and oxygen-glucose deprivation in mouse hippocampal slice cultures...
  5. ncbi request reprint Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures
    Maria Montero
    Department of Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winsløwparken 21 st, DK 5000 Odense C, Denmark
    Exp Neurol 204:106-17. 2007
    ..Both EPO and CEPO significantly reduced formation of spectrin cleavage products in the OGD model. We conclude that CEPO is at least as efficient neuroprotectant as EPO when excitotoxicity is modeled in mouse hippocampal slice cultures...
  6. ncbi request reprint The GABAA receptor agonist THIP is neuroprotective in organotypic hippocampal slice cultures
    Bjarne W Kristensen
    Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winsløwparken 21, DK 5000 Odense C, Denmark
    Brain Res 973:303-6. 2003
    ..The results demonstrate that direct GABA(A) agonism can mediate neuroprotection in the hippocampus in vitro as previously suggested in vivo...
  7. ncbi request reprint Colchicine induces apoptosis in organotypic hippocampal slice cultures
    Bjarne W Kristensen
    Department of Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winsløwparken 21, DK 5000 C, Odense, Denmark
    Brain Res 964:264-78. 2003
    ..We conclude that colchicine induces caspase 3-dependent apoptotic cell death of dentate granule cells in hippocampal brain slice cultures, but the apoptotic cell death is highly dependent on the developmental stage of the cultures...
  8. ncbi request reprint Nuclear shrinkage and other markers of neuronal cell death after oxygen-glucose deprivation in rat hippocampal slice cultures
    Christian Bonde
    Anatomy and Neurobiology, University of Southern Denmark, Winslowparken 21, 5000 Odense C, Denmark
    Neurosci Lett 327:49-52. 2002
    ..We conclude that shrinkage of Hoechst 33342 stained neuronal nuclei detected by image analysis is an early and easily quantifiable indicator of neuronal degeneration in hippocampal slice cultures...
  9. doi request reprint Zbtb20-induced CA1 pyramidal neuron development and area enlargement in the cerebral midline cortex of mice
    Jakob V Nielsen
    Molecular Neurobiology Laboratory, Medical Biotechnology Center, Department of Molecular Medicine, University of Southern Denmark, J B Winslows Vej 25, DK 5000 Odense C, Denmark
    Cereb Cortex 20:1904-14. 2010
    ..They further suggest that Zbtb20 plays a role in arealization of the midline cortex...
  10. ncbi request reprint Organotypic hippocampal slice cultures for studies of brain damage, neuroprotection and neurorepair
    Jens Noraberg
    Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Odense, Denmark
    Curr Drug Targets CNS Neurol Disord 4:435-52. 2005
    ....
  11. ncbi request reprint 3-Nitropropionic acid neurotoxicity in hippocampal slice cultures: developmental and regional vulnerability and dependency on glucose
    Helle Noer
    Anatomy and Neurobiology, SDU Odense University, Denmark
    Exp Neurol 176:237-46. 2002
    ....
  12. ncbi request reprint Hippocampus-like corticoneurogenesis induced by two isoforms of the BTB-zinc finger gene Zbtb20 in mice
    Jakob V Nielsen
    Molecular Neurobiology Laboratory, Medical Biotechnology Center, University of Southern Denmark, J B Winslowsvej 25, DK 5000 Odense C, Denmark
    Development 134:1133-40. 2007
    ..Overall, our in vivo data suggest that Zbtb20 functions as a molecular switch for a pathway that induces invariant pyramidal neuron morphogenesis and suppression of cell fate transitions in newborn neurons...
  13. ncbi request reprint Quantitative on-line monitoring of hippocampus glucose and lactate metabolism in organotypic cultures using biosensor technology
    Jan Bert Gramsbergen
    Department of Anatomy and Neurobiology, SDU Odense University, Odense, Denmark
    J Neurochem 85:399-408. 2003
    ..The data show that maintaining Na+ and K+ gradients consumed much of the energy but do not support the hypothesis that l-glutamate stimulates glycolysis in hippocampal slice cultures...
  14. ncbi request reprint Changes in extracellular action potential detect kainic acid and trimethyltin toxicity in hippocampal slice preparations earlier than do MAP2 density measurements
    Raffaella Melani
    Department of Neuroscience, Ophthalmology and Genetics, University of Genoa, Via De Toni 5, 16132 Genoa, Italy
    Altern Lab Anim 33:379-86. 2005
    ..Electrophysiology could be a reliable and early indicator of neurotoxicity, which could improve our ability to test for neurotoxicity in vitro, thus further replacing the need for in vivo experimentation...
  15. ncbi request reprint The assessment of repeated dose toxicity in vitro: a proposed approach. The report and recommendations of ECVAM workshop 56
    Pilar Prieto
    ECVAM, Institute for Health and Consumer Protection, European Joint Research Centre, 21020 Ispra VA, Italy
    Altern Lab Anim 34:315-41. 2006